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Luxury Hotels in Panama from $131

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Top Cities in Panama

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Panama City

Panama City

Check availability on Panama Luxury Hotels

Tonight
Nov 26 - Nov 27
Tomorrow
Nov 27 - Nov 28
This weekend
Nov 28 - Nov 30
Next weekend
Dec 5 - Dec 7

Pick from 67 Panama Luxury Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

4 outdoor pools, free cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

5.0 star property
San Francisco
  • Ocean-view dining
  • 24-hour gym
  • Poolside bar
  • Concierge services
9.0 out of 10, Wonderful, (1009)
Panoramic vistas complement upscale amenities at this waterfront haven. Guests savor Latin American cuisine at the ocean-view restaurant, unwind with poolside cocktails, and enjoy pampering spa services. Spacious rooms feature premium bedding, designer toiletries, and private balconies overlooking the scenic surroundings.
$212 nightly
The price is $233
Dec 7 - Dec 8
Total with taxes and fees
JW Marriott Panama
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5.0 star property
Bella Vista
  • 2 bars
  • Full-service spa
  • Poolside bar
  • Concierge services
9.2 out of 10, Wonderful, (1007)
Sumptuous spa treatments await at this art deco retreat where pillowtop beds and Egyptian cotton sheets create havens of comfort. Steps from Calle 50, guests savor international cuisine at the restaurant while enjoying attentive service in refined surroundings.
$179 nightly
The price is $196
Dec 19 - Dec 20
Total with taxes and fees
Bristol Panama, a Registry Collection Hotel
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

5.0 star property
Bella Vista
  • 2 restaurants
  • Full-service spa
  • Poolside bar
  • Concierge services
9.0 out of 10, Wonderful, (1004)
Sophisticated luxury awaits at this Panama City retreat where spa indulgence meets refined hospitality. Savor exceptional cuisine at 2 restaurants, unwind with champagne service, or relax poolside with attentive service. Steps from shopping and cultural landmarks.
$171 nightly
The price is $189
Dec 6 - Dec 7
Total with taxes and fees
Waldorf Astoria Panama
Front of property - evening/night
American Trade Hotel

American Trade Hotel

4.5 star property
Casco Viejo
  • Outdoor pool
  • Concierge services
9.4 out of 10, Exceptional, (593)
Champagne service and massage treatments elevate stays at this colonial masterpiece. Guests swim in the 24-hour outdoor pool, dine on praised cuisine in the elegant restaurant, and sleep on Frette Italian sheets after exploring nearby museums.
$232 nightly
The price is $257
Dec 3 - Dec 4
Total with taxes and fees
American Trade Hotel
Meeting facility
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 star property
Bella Vista
  • Full-service spa
  • Poolside bar
  • Concierge services
8.8 out of 10, Excellent, (1004)
Sophisticated relaxation awaits at this luxury Panama retreat. The 10-treatment-room Sortis Spa offers Ayurvedic therapies, body wraps, and facials, while the outdoor pool provides sun-drenched serenity. Casino gaming and exceptional dining complete the upscale experience.
$159 nightly
The price is $175
Nov 30 - Dec 1
Total with taxes and fees
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Outdoor pool
Hilton Panama

Hilton Panama

5.0 star property
Bella Vista
  • 4 restaurants
  • Full-service spa
  • Poolside bar
  • Concierge services
8.8 out of 10, Excellent, (1002)
Sophisticated relaxation defines this Panama City retreat where an attached winery complements 4 restaurants and 2 bars. Eforea Spa pampers with 8 treatment rooms, aromatherapy services, and hot stone massages, while the casino and outdoor pool create a complete luxury experience.
$185 nightly
The price is $204
Dec 7 - Dec 8
Total with taxes and fees
Hilton Panama
View from property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

5.0 star property
San Francisco
  • 4 restaurants
  • Full-service spa
  • Poolside bar
  • Concierge services
8.4 out of 10, Very Good, (1001)
Sophisticated relaxation unfolds at this 5-star retreat's spa with 10 treatment rooms offering Swedish massages and aromatherapy. Guests delight in 4 restaurants, 4 stylish bars, and 2 hot tubs. The casino, nightclub, and poolside service complete this lavish Panama City experience.
Megapolis Hotel Panamá
12 outdoor pools, cabanas (surcharge), pool umbrellas
The Buenaventura Golf & Beach Resort Panama, Autograph Collection

The Buenaventura Golf & Beach Resort Panama, Autograph Collection

5.0 star property
El Chiru
  • On private beach
  • Beachfront dining
  • Full-service spa
  • 2 poolside bars
  • Concierge services
9.2 out of 10, Wonderful, (679)
Coastal luxury unfolds across this expansive Panama retreat, where 12 magnificent pools sparkle under tropical skies. Indulgent spa treatments await in 5 dedicated rooms, while 7 restaurants serve delectable cuisine. Black sand beaches, meticulously maintained gardens, and championship golf complete the sophisticated escape.
$164 nightly
The price is $180
Dec 14 - Dec 15
Total with taxes and fees
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4.0 star property
San Francisco
  • Full-service spa
  • Indoor pool
  • Concierge services
9.0 out of 10, Wonderful, (1023)
Luxurious relaxation defines this upscale retreat. Sona Spa and Wellness offers daily pampering treatments, while an indoor pool, sauna, and fitness center provide recreational sanctuaries. Premium dining experiences await at the restaurant, complemented by a stylish bar for evening unwinding.
$118 nightly
The price is $131
Dec 6 - Dec 7
Total with taxes and fees
Las Americas Golden Tower Panama
Terrace/patio
Marriott Panama Hotel

Marriott Panama Hotel

4.0 star property
Panama City
  • 2 restaurants
  • 24-hour gym
  • Poolside bar
  • Concierge services
9.0 out of 10, Wonderful, (1011)
Marble bathrooms and plush bedding welcome travelers at this Panama City sanctuary. Overlooking the cityscape, the rooftop pool provides refreshing respite after exploring nearby museums or shopping at Albrook Mall. Both restaurants serve international cuisine with impeccable attention to detail.
$142 nightly
The price is $156
Dec 7 - Dec 8
Total with taxes and fees
Marriott Panama Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

10/10 Excellent
"Easy parking. Lots of noise from the road"
Heather 1-night trip
Posted 2 days ago
Plaza Paitilla Inn Hotel