Title: Best Apartments in Panama for Your Vacation from $76 | Expedia.com [Panama Travel Guide](https://expedia.com/Panama.dx142)[Panama Hotels](https://expedia.com/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Things to do in Panama](https://expedia.com/Things-To-Do-In-Panama.d142.Travel-Guide-Activities)[Car Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 24 - Jul 26](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-07-24&endDate=2026-07-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Cities in Panama ![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.com/Panama-City-Apartments.d2897-aaApartments.Travel-Guide-Accommodation) ![ISLA COLON BOCAS DEL TORO](https://images.trvl-media.com/place/6023445/f17b18cc-4a72-405d-ab41-dfd48c15b97d.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.com/Bocas-Del-Toro-Apartments.d6023445-aaApartments.Travel-Guide-Accommodation) ![Idyllic Sunset at Playa Blanca, Panama](https://images.trvl-media.com/place/6246042/058a4e01-e481-4197-9791-26c53b4ee917.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Rio Hato [](https://expedia.com/Rio-Hato-Apartments.d6246042-aaApartments.Travel-Guide-Accommodation) ![Sunrise with a view at Volcán Barú in Panama](https://images.trvl-media.com/place/500194/a9fdba1c-ad36-4683-90ac-2cdb584e103b.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Boquete [](https://expedia.com/Boquete-Apartments.d500194-aaApartments.Travel-Guide-Accommodation) ![Traditional dances of the state of Veracruz Mexico, typical clothes.](https://images.trvl-media.com/place/6360124/8b5bd5dc-d1e8-4f62-8efa-6c53ea07e013.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Veracruz [](https://expedia.com/Veracruz-Apartments.d6360124-aaApartments.Travel-Guide-Accommodation) ![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Colon [](https://expedia.com/Colon-Apartments.d601867-aaApartments.Travel-Guide-Accommodation) ## Our top choices for Panama apartments ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/362ba912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/7cba0a34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/a4be5f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Balcony](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/97c51ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panama [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) Bella Vista 7.6/10 Good (273 reviews) "Great location and good amenities for 1st time travellers Pool view is amazing... " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) nikita $132 nightly $144 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7fec4ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/83a9c463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7d5bd8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/2f5f574e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panamá by Boutique Apartments [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) Bella Vista 8.0/10 Very Good (81 reviews) "The stay was wonderful. Highly recommend. Great value. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Joseph $198 nightly $204 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/4fefbf57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/c45dedaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Television](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/e5394f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/6445192b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) San Francisco 7.4/10 Good (180 reviews) "Would recommend this stay to anyone I know who is visiting Panama. We loved our room and also the check in process was easy! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrena $178 nightly $195 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Apartment, 3 Bedrooms (4B) | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/edb72763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (2C) | Balcony](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/273fe814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms (4B) | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/17257b2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3B) | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/3372238d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donovan By Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) Casco Viejo 8.2/10 Very Good (58 reviews) "Excellent room and good location. I did not receive security door or room code . Another hotel ckerk was able to reach then fir me at 8pm at night when i arrived. The place as a tiny sign in black that yu will miss. Otherwise great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tashi $141 nightly $152 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) ![Premier Suite, 1 King Bed, Garden View | Premium bedding, down comforters, individually decorated](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/f5f9cdd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Suite, 1 King Bed, Mountain View | Private kitchen | Fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/98fdcd03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/876ac108.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Garden View | Living area | 43-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/a6c217b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cielo by Villa Alejandro [](https://www.expedia.com/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) Boquete 9.4/10 Exceptional (106 reviews) "Everything was perfect! The room was comfortable and clean. The proximity to town was great!Communication with the hosts was excellent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lee $87 nightly $96 total May 3 - May 4 Total with taxes and fees [](https://www.expedia.com/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) ![Apartment (1D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/c78eb228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/569ccb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/1cdad385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3D) | Private kitchen | Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/bf9924b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa La Costa By Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) Casco Viejo 8.6/10 Excellent (27 reviews) "Location was beautiful. Cleanliness, not so good. The bed was rock hard with lumps and it was a very loud location, between a bar and the upstairs unit had a lot of people or parties. Great for the view, not so much for sleeping." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley $138 nightly $152 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) ![Apartment, 2 Bedrooms (1B) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/9e77777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Private kitchen | Coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/04577a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/4443ba1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1C) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/7717b8f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Love by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) Casco Viejo 9.0/10 Wonderful (24 reviews) "Large, clean rooms, lots of space. Great bathroom. Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joette $140 nightly $154 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) ![Apartment, 2 Bedrooms (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/42608a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/fc090f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/0447e43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1C) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/50831da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Lefevre By Wynwood House [](https://www.expedia.com/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) Casco Viejo 9.4/10 Exceptional (11 reviews) "Staff was courteous, and the room was very beautiful. Would stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Selam $180 nightly $198 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (10C) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/ea03f013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/f99400a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/2fdde3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) San Francisco 7.6/10 Good (35 reviews) "The place was clean nice an its comfortable an the view is to kill for amazing ‼️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Odaine $140 nightly $153 total May 3 - May 4 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Deluxe Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/0a2a9e4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Balcony](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/3c59dc38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/6f82906f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/b8edc80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Moderna by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) Casco Viejo 7.4/10 Good (45 reviews) "Great area. Close proximity to everything in Casco Viejo Water escapes from shower area to flood bathroom area while showering. Property could do with some landscaping. An overall fair experience. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aujae $114 nightly $125 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) ![Luxury Apartment | View from room](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/ead1ae24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/9bcaeb29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/f778c834.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/e6079dcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Surfside Beachfront Suites by Playa Caracol Resorts [](https://www.expedia.com/Punta-Chame-Hotels-Playa-Caracol-Residences-Vacation-Rental.h39130628.Hotel-Information) Punta Chame 7.6/10 Good (37 reviews) "Love this trip your own private paradise we are definitely going again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Solomon $195 nightly $215 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Punta-Chame-Hotels-Playa-Caracol-Residences-Vacation-Rental.h39130628.Hotel-Information) ![Comfort Suite, 1 Queen Bed with Sofa bed | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/2462f537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/6bfa829b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/53efba5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Palma Experience [](https://www.expedia.com/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) Amador 8.4/10 Very Good (7 reviews) "All ways clean and ready to used ,no buddy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto $69 nightly $76 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) ![Superior Suite, 1 King Bed, Valley View, Mountainside | Private spa tub](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/6e28a490.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed, Valley View, Mountainside | Laptop workspace, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/7ab9b645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed, Kitchenette, Valley View | Laptop workspace, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/aae728ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/4310cfd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Reina by Villa Alejandro [](https://www.expedia.com/Boquete-Hotels-Casa-Reina-By-Villa-Alejandro.h111493077.Hotel-Information) Boquete 8.6/10 Excellent (19 reviews) "Be aware the road, or trail more like it, to the hotel is very rough, only 1 lane in same areas. Check in took 15 minutes, with remote concierge. Views from balcony is great. Grounds are well kept. lots of small birds singing. Room is large and king bed is comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim $83 nightly $92 total Apr 30 - May 1 Total with taxes and fees [](https://www.expedia.com/Boquete-Hotels-Casa-Reina-By-Villa-Alejandro.h111493077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/94d2f2bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/600a3940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![15 outdoor pools](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/bee413e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Private kitchen](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/ac3f0393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Apartment Piso 35 with City View [](https://www.expedia.com/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) Bella Vista 10/10 Exceptional (1 review) "I had a wonderful stay at this property The property was exceptionally clean, and the staff went above and beyond to make sure I felt welcome. Early check in. Highly recommended." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre [](https://www.expedia.com/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) ![Apartment, 2 Bedrooms (CC2A) | Premium bedding, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/a1353e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC2B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/86dc292b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC4A) | Balcony](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/90de29d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/w2000h1310x0y0-5cea16ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Contemporanea by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) Casco Viejo 8.2/10 Very Good (22 reviews) "Cute place, well located. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Stephanie $177 nightly $192 total Apr 15 - Apr 16 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) ![Apartment, 3 Bedrooms (CM5) | Living room | 55-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/67865bff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/932f3bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CM1) | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/776d053a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/c3f1232b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Mallet by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) Casco Viejo 9.8/10 Exceptional (27 reviews) "It was amazing! Staff was easy to contact. Very clean apartment and great location with shops and restuarants nearby. Patio with chairs to overlook the area. Couldnt have had a better stay. Excellent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chisina [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/7731b155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch TV with cable channels](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/24c4ebfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/16f7b9a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/5ace70c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Apartamento [](https://www.expedia.com/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information) Bella Vista 9.2/10 Wonderful (17 reviews) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jimmy Lee $128 nightly $141 total Apr 22 - Apr 23 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/w1023h982x0y0-cbf9c42c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/f77ce1e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/0a183484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/8b11030c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Apartment With Private Beach And Sea View [](https://www.expedia.com/Veracruz-Hotels-Luxury-Apartment-With-Private-Beach-And-Sea-View.h83097642.Hotel-Information) Panama City 10/10 Exceptional (13 reviews) "Property was beautiful and really enjoyed the Pearl Club" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra C. [](https://www.expedia.com/Veracruz-Hotels-Luxury-Apartment-With-Private-Beach-And-Sea-View.h83097642.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/fe2a6d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/e3d1e67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/cf6fd2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/3a92f4c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza Catedral Views by AcoModo [](https://www.expedia.com/Panama-City-Hotels-2-Bdr-2-Bthr-Apartment-In-Casco-Viejo-Near-Sites-Of-Interest.h106499044.Hotel-Information) Casco Viejo 8.0/10 Very Good (4 reviews) "We came back after 3 weeks of our first stay. We loved this place so much that we could not resist to use it again. We used the stove and all kitchen facilities this time and we enjoyed our stay even more. Having breakfast in the appartment with the central park view is just priceless.I traveled with my mother of 80 years old and although I was concerned about the stairs, this was never an issue. This place is clean, safe, has a wonderful location if you use Uber to go around and it... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lilliam V. $148 nightly $148 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-2-Bdr-2-Bthr-Apartment-In-Casco-Viejo-Near-Sites-Of-Interest.h106499044.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/335c377d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/6ab36353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/cbf3f070.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/b0b19c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Location, 2 bed, 2baths, High Speed Internet [](https://www.expedia.com/Panama-City-Hotels-Best-Location.h90707371.Hotel-Information) Bella Vista 9.2/10 Wonderful (9 reviews) "City hop on hop off is just around the corner." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nilesh J. [](https://www.expedia.com/Panama-City-Hotels-Best-Location.h90707371.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-18&endDate=2026-04-19®ionId=142&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Villas [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-03&d1=2026-07-03&endDate=2026-07-06&d2=2026-07-06&lodging=VILLA) Cabins [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-03&d1=2026-07-03&endDate=2026-07-06&d2=2026-07-06&lodging=CABIN) Apartments [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-03&d1=2026-07-03&endDate=2026-07-06&d2=2026-07-06&lodging=APARTMENT) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-03&d1=2026-07-03&endDate=2026-07-06&d2=2026-07-06&lodging=VACATION_HOME) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-03&d1=2026-07-03&endDate=2026-07-06&d2=2026-07-06&lodging=APART_HOTEL) Condos [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-03&d1=2026-07-03&endDate=2026-07-06&d2=2026-07-06&lodging=CONDO) Houseboats [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-03&d1=2026-07-03&endDate=2026-07-06&d2=2026-07-06&lodging=HOUSE_BOAT) Cottages [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-03&d1=2026-07-03&endDate=2026-07-06&d2=2026-07-06&lodging=COTTAGE) Chalets [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-03&d1=2026-07-03&endDate=2026-07-06&d2=2026-07-06&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanama-Apartments.d142-aaApartments.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanama-Apartments.d142-aaApartments.Travel-Guide-Accommodation) ## Top Panama Hotel Reviews ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "Was excellent all the staff " [](https://expedia.com/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg) ### The Executive Hotel 10/10 Excellent "We like this hotel because it’s not as big as other hotels. Clean rooms. Nice pool. Within walking distance of several great restaurants. " [](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 8/10 Good "Good " [](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The staff was very nice and helpful the room was beautiful " [](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Stay was great as ever." [](https://expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg) ### Waymore Hotel Spa & Casino 6/10 Okay "We chose to stay at the Waymore for our honeymoon to Panama. The best thing about this hotel is the location. There were a lot of food options and souvenir shops within walking distance of the hotel. I was sad to find out that the pool was closed for remodeling-they did not inform us of this prior to our stay. Hotel staff did offer the option to go to a nearby hotel 15 minutes away and use their pool and even offered a complimentary shuttle service to get there. Breakfast was only okay. They offered the same thing every single day. The hotel advertised a chef to prepare eggs on the spot- I never found this. The hot lamps didn't keep the food hot, instead it tasted soggy and slightly warm. When we first checked into the room, the soap dispenser on the wall was practically empty and this was NEVER refilled during our 8 night stay. The water pressure in the shower was very spotty sometimes would barely drip out. The water wasn't wasn't always hot and we found ourselves showering with cold water at times. I think one of the biggest complaints of our stay is that there was a maintenance worker on a scaffold right outside of our window and mind you we were staying on like the 12th floor. The maintenance worker was outside our window at like 10 AM when our curtains were wide open and I had just gotten out of the shower and was trying to get dressed. The hotel room had 1 singular light in the ceiling which barely provided any lighting- so we had to close the shades. " [](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Place is great and staff is awesome " [](https://expedia.com/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Excellent and convenient location, very clean, and equipped with complete amenities. Ideal for business stays. The staff could be a bit friendlier, though I later realized this seems to be the norm in the country." [](https://expedia.com/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Hotel Riu Playa Blanca - All Inclusive](https://images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/737d5dbd_y.jpg) ### Hotel Riu Playa Blanca - All Inclusive 10/10 Excellent "Best value for your buck! Had no issues, enjoyed the place—great evening entertainment, which we appreciated. The beach is nice, and we never struggled to find seats by the pool or on the beach, as some previous reviews mentioned. The food was great; however, I didn't find the special restaurants worth the hassle of getting in. All in all, I recommend it for the nice weather, the great beach, and the nice staff. The staff can also do a better job of responding to room requests. We had to do some back-and-forth on replacement items. " [](https://expedia.com/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information) ## Find out more about Panama ## Panama Apartments information | Number of reviews | 865 | | ----------------- | --------------- | | Accommodation | 1681 Apartments | | Lowest Price | $76 | | Highest Price | $286 | ## Explore a world of travel with Expedia - Lodging - Packages - Cars - [Hotels near Sante Fe National Park ](https://www.expedia.com/Sante-Fe-National-Park-Hotels.0-l553248635976022317-0.Travel-Guide-Filter-Hotels) - [Sante Fe National Park ](https://www.expedia.com/Sante-Fe-National-Park-Panama.d553248635976022317.Vacation-Attraction) - [Car rentals near Sante Fe National Park ](https://www.expedia.com/Car-Rentals-In-Sante-Fe-National-Park.d553248635976022317.Car-Rental-Guide)