Title: Best Apartments in Panama for Your Vacation from $83 | Expedia.com [Panama Travel Guide](https://expedia.com/Panama.dx142)[Panama Hotels](https://expedia.com/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Things to do in Panama](https://expedia.com/Things-To-Do-In-Panama.d142.Travel-Guide-Activities)[Car Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 24 - Jul 26](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-07-24&endDate=2026-07-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Cities in Panama ![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.com/Panama-City-Apartments.d2897-aaApartments.Travel-Guide-Accommodation) ![ISLA COLON BOCAS DEL TORO](https://images.trvl-media.com/place/6023445/f17b18cc-4a72-405d-ab41-dfd48c15b97d.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.com/Bocas-Del-Toro-Apartments.d6023445-aaApartments.Travel-Guide-Accommodation) ![Idyllic Sunset at Playa Blanca, Panama](https://images.trvl-media.com/place/6246042/058a4e01-e481-4197-9791-26c53b4ee917.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Rio Hato [](https://expedia.com/Rio-Hato-Apartments.d6246042-aaApartments.Travel-Guide-Accommodation) ![Sunrise with a view at Volcán Barú in Panama](https://images.trvl-media.com/place/500194/a9fdba1c-ad36-4683-90ac-2cdb584e103b.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Boquete [](https://expedia.com/Boquete-Apartments.d500194-aaApartments.Travel-Guide-Accommodation) ![Traditional dances of the state of Veracruz Mexico, typical clothes.](https://images.trvl-media.com/place/6360124/8b5bd5dc-d1e8-4f62-8efa-6c53ea07e013.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Veracruz [](https://expedia.com/Veracruz-Apartments.d6360124-aaApartments.Travel-Guide-Accommodation) ![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Colon [](https://expedia.com/Colon-Apartments.d601867-aaApartments.Travel-Guide-Accommodation) ## Our top choices for Panama apartments ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/362ba912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/7cba0a34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/737ceca4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Balcony](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/97c51ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panama [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) Bella Vista 7.6/10 Good (273 reviews) "Great location and good amenities for 1st time travellers Pool view is amazing... " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) nikita $136 nightly $149 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7fec4ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/83a9c463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/c6184862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7d5bd8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panamá by Boutique Apartments [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) Bella Vista 8.0/10 Very Good (78 reviews) "The stay was wonderful. Highly recommend. Great value. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Joseph $216 nightly $223 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/4fefbf57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/6445192b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/c45dedaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Television](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/e5394f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) San Francisco 7.6/10 Good (178 reviews) "Would recommend this stay to anyone I know who is visiting Panama. We loved our room and also the check in process was easy! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrena $178 nightly $195 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Apartment, 3 Bedrooms (4B) | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/edb72763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3B) | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/3372238d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1C) | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/dc6d18df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms (4B) | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/17257b2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donovan By Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) Casco Viejo 8.2/10 Very Good (58 reviews) "Excellent room and good location. I did not receive security door or room code . Another hotel ckerk was able to reach then fir me at 8pm at night when i arrived. The place as a tiny sign in black that yu will miss. Otherwise great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tashi $141 nightly $152 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) ![Premier Suite, 1 King Bed, Garden View | Premium bedding, down comforters, individually decorated](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/f5f9cdd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Garden View | Living area | 43-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/a6c217b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/876ac108.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Suite, 1 King Bed, Mountain View | Private kitchen | Fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/98fdcd03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cielo by Villa Alejandro [](https://www.expedia.com/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) Boquete 9.4/10 Exceptional (105 reviews) "Everything was perfect! The room was comfortable and clean. The proximity to town was great!Communication with the hosts was excellent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lee $88 nightly $96 total May 3 - May 4 Total with taxes and fees [](https://www.expedia.com/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) ![Apartment (1D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/c78eb228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/1cdad385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/569ccb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3D) | Private kitchen | Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/bf9924b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa La Costa By Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) Casco Viejo 8.6/10 Excellent (27 reviews) "Location was beautiful. Cleanliness, not so good. The bed was rock hard with lumps and it was a very loud location, between a bar and the upstairs unit had a lot of people or parties. Great for the view, not so much for sleeping." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley $138 nightly $152 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) ![Apartment, 2 Bedrooms (1B) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/9e77777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1D) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/3f9c0f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Private kitchen | Coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/04577a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/4443ba1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Love by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) Casco Viejo 9.0/10 Wonderful (24 reviews) "Large, clean rooms, lots of space. Great bathroom. Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joette $131 nightly $144 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) ![Apartment, 2 Bedrooms (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/42608a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/9a31f88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1C) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/50831da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/fc090f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Lefevre By Wynwood House [](https://www.expedia.com/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) Casco Viejo 9.4/10 Exceptional (11 reviews) "Staff was courteous, and the room was very beautiful. Would stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Selam $180 nightly $198 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/4bc61653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/2fdde3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/f99400a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) San Francisco 7.6/10 Good (35 reviews) "The place was clean nice an its comfortable an the view is to kill for amazing ‼️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Odaine $140 nightly $153 total May 3 - May 4 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Deluxe Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/0a2a9e4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/6f82906f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Balcony](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/3c59dc38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97957e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Moderna by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) Casco Viejo 7.4/10 Good (45 reviews) "Great area. Close proximity to everything in Casco Viejo Water escapes from shower area to flood bathroom area while showering. Property could do with some landscaping. An overall fair experience. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aujae $106 nightly $117 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) ![Luxury Apartment | View from room](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/ead1ae24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/9bcaeb29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/e6079dcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/f778c834.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Surfside Beachfront Suites by Playa Caracol Resorts [](https://www.expedia.com/Punta-Chame-Hotels-Playa-Caracol-Residences-Vacation-Rental.h39130628.Hotel-Information) Punta Chame 7.6/10 Good (37 reviews) "Love this trip your own private paradise we are definitely going again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Solomon $195 nightly $215 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Punta-Chame-Hotels-Playa-Caracol-Residences-Vacation-Rental.h39130628.Hotel-Information) ![Comfort Suite, 1 Queen Bed with Sofa bed | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/2462f537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/6bfa829b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/53efba5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Palma Experience [](https://www.expedia.com/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) Amador 8.4/10 Very Good (7 reviews) "All ways clean and ready to used ,no buddy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto $76 nightly $83 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) ![Superior Suite, 1 King Bed, Valley View, Mountainside | Private spa tub](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/6e28a490.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed, Kitchenette, Valley View | Laptop workspace, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/13fd7cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/4310cfd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed, Valley View, Mountainside | Laptop workspace, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/7ab9b645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Reina by Villa Alejandro [](https://www.expedia.com/Boquete-Hotels-Casa-Reina-By-Villa-Alejandro.h111493077.Hotel-Information) Boquete 8.6/10 Excellent (19 reviews) "Be aware the road, or trail more like it, to the hotel is very rough, only 1 lane in same areas. Check in took 15 minutes, with remote concierge. Views from balcony is great. Grounds are well kept. lots of small birds singing. Room is large and king bed is comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim $83 nightly $92 total Apr 28 - Apr 29 Total with taxes and fees [](https://www.expedia.com/Boquete-Hotels-Casa-Reina-By-Villa-Alejandro.h111493077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/94d2f2bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/7c635746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/600a3940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![15 outdoor pools](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/bee413e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Apartment Piso 35 with City View [](https://www.expedia.com/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) Bella Vista 10/10 Exceptional (1 review) "I had a wonderful stay at this property The property was exceptionally clean, and the staff went above and beyond to make sure I felt welcome. Early check in. Highly recommended." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre [](https://www.expedia.com/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) ![Apartment, 2 Bedrooms (CC2A) | Premium bedding, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/a1353e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC2B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/86dc292b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/w2000h1310x0y0-5cea16ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC4A) | Balcony](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/90de29d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Contemporanea by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) Casco Viejo 8.2/10 Very Good (22 reviews) "Cute place, well located. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Stephanie $177 nightly $192 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) ![Apartment, 3 Bedrooms (CM5) | Living room | 55-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/67865bff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/1a0cf4a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CM1) | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/776d053a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/c3f1232b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Mallet by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) Casco Viejo 9.8/10 Exceptional (27 reviews) "It was amazing! Staff was easy to contact. Very clean apartment and great location with shops and restuarants nearby. Patio with chairs to overlook the area. Couldnt have had a better stay. Excellent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chisina [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/7731b155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch TV with cable channels](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/24c4ebfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/16f7b9a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/b23e7852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Apartamento [](https://www.expedia.com/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information) Bella Vista 9.2/10 Wonderful (17 reviews) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jimmy Lee $128 nightly $141 total Apr 22 - Apr 23 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/w1023h982x0y0-cbf9c42c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/698dc46b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/0a183484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/f77ce1e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Apartment With Private Beach And Sea View [](https://www.expedia.com/Veracruz-Hotels-Luxury-Apartment-With-Private-Beach-And-Sea-View.h83097642.Hotel-Information) Panama City 10/10 Exceptional (13 reviews) "Property was beautiful and really enjoyed the Pearl Club" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra C. [](https://www.expedia.com/Veracruz-Hotels-Luxury-Apartment-With-Private-Beach-And-Sea-View.h83097642.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/fe2a6d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/53709432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/cf6fd2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/3a92f4c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza Catedral Views by AcoModo [](https://www.expedia.com/Panama-City-Hotels-2-Bdr-2-Bthr-Apartment-In-Casco-Viejo-Near-Sites-Of-Interest.h106499044.Hotel-Information) Casco Viejo 8.0/10 Very Good (4 reviews) "We came back after 3 weeks of our first stay. We loved this place so much that we could not resist to use it again. We used the stove and all kitchen facilities this time and we enjoyed our stay even more. Having breakfast in the appartment with the central park view is just priceless.I traveled with my mother of 80 years old and although I was concerned about the stairs, this was never an issue. This place is clean, safe, has a wonderful location if you use Uber to go around and it... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lilliam V. $143 nightly $143 total Apr 28 - Apr 29 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-2-Bdr-2-Bthr-Apartment-In-Casco-Viejo-Near-Sites-Of-Interest.h106499044.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/335c377d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/b0b19c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/df336211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/cbf3f070.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Location, 2 bed, 2baths, High Speed Internet [](https://www.expedia.com/Panama-City-Hotels-Best-Location.h90707371.Hotel-Information) Bella Vista 9.2/10 Wonderful (9 reviews) "City hop on hop off is just around the corner." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nilesh J. [](https://www.expedia.com/Panama-City-Hotels-Best-Location.h90707371.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-16&endDate=2026-04-17®ionId=142&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Villas [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=VILLA) Cabins [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=CABIN) Apartments [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=APARTMENT) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=VACATION_HOME) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=APART_HOTEL) Condos [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=CONDO) Cottages [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=COTTAGE) Houseboats [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=HOUSE_BOAT) Chalets [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-01&d1=2026-07-01&endDate=2026-07-04&d2=2026-07-04&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanama-Apartments.d142-aaApartments.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanama-Apartments.d142-aaApartments.Travel-Guide-Accommodation) ## Top Panama Hotel Reviews ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg) ### Sheraton Grand Panama 8/10 Good "The breakfast menu was excellent. It covers ever taste." [](https://expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Staff were all very friendly Food was excellent Very clean everywhere" [](https://expedia.com/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg) ### The Executive Hotel 10/10 Excellent "Excellent breakfast. Modern and clean. Good location." [](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Room was great, clean, friendly staff, and very convenient location." [](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg) ### Waymore Hotel Spa & Casino 8/10 Good "I didnt use the breakfast nor parking, but the casino was ok." [](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Ramada Plaza by Wyndham Panama Punta Pacifica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b_y.jpg) ### Ramada Plaza by Wyndham Panama Punta Pacifica 10/10 Excellent "Clean and beautiful room. Comfortable beds. Breakfast was good. Wished there was another choice of protein besides pork, not everyone eats pork." [](https://expedia.com/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 6/10 Okay "It’s very convenient for shopping " [](https://expedia.com/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Hotel Riu Playa Blanca - All Inclusive](https://images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/737d5dbd_y.jpg) ### Hotel Riu Playa Blanca - All Inclusive 10/10 Excellent "The staff was amazing, the food was great, and it was a very family friendly experience!!! Couldn't recommend higher!!!" [](https://expedia.com/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "I really enjoyed my stay. I went there on the 24th of march and left today, which is the 31st of march 2026\. There restaurants where so near by and a food store next door the pool was good the rooms where very nice. The only thing was missing was having a microwave in the rooms other wise the rooms met my expectations. " [](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ## Find out more about Panama ## Panama Apartments information | Number of reviews | 863 | | ----------------- | --------------- | | Accommodation | 1681 Apartments | | Lowest Price | $83 | | Highest Price | $223 | ## Explore a world of travel with Expedia - Lodging - Packages - Cars - [Hotels near Sante Fe National Park ](https://www.expedia.com/Sante-Fe-National-Park-Hotels.0-l553248635976022317-0.Travel-Guide-Filter-Hotels) - [Sante Fe National Park ](https://www.expedia.com/Sante-Fe-National-Park-Panama.d553248635976022317.Vacation-Attraction) - [Car rentals near Sante Fe National Park ](https://www.expedia.com/Car-Rentals-In-Sante-Fe-National-Park.d553248635976022317.Car-Rental-Guide)