Title: Best Apartments in Panama for Your Vacation from $83 | Expedia.com [Panama Travel Guide](https://expedia.com/Panama.dx142)[Panama Hotels](https://expedia.com/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Things to do in Panama](https://expedia.com/Things-To-Do-In-Panama.d142.Travel-Guide-Activities)[Car Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 24 - Jul 26](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-07-24&endDate=2026-07-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Cities in Panama ![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.com/Panama-City-Apartments.d2897-aaApartments.Travel-Guide-Accommodation) ![ISLA COLON BOCAS DEL TORO](https://images.trvl-media.com/place/6023445/f17b18cc-4a72-405d-ab41-dfd48c15b97d.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.com/Bocas-Del-Toro-Apartments.d6023445-aaApartments.Travel-Guide-Accommodation) ![Idyllic Sunset at Playa Blanca, Panama](https://images.trvl-media.com/place/6246042/058a4e01-e481-4197-9791-26c53b4ee917.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Rio Hato [](https://expedia.com/Rio-Hato-Apartments.d6246042-aaApartments.Travel-Guide-Accommodation) ![Sunrise with a view at Volcán Barú in Panama](https://images.trvl-media.com/place/500194/a9fdba1c-ad36-4683-90ac-2cdb584e103b.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Boquete [](https://expedia.com/Boquete-Apartments.d500194-aaApartments.Travel-Guide-Accommodation) ![Traditional dances of the state of Veracruz Mexico, typical clothes.](https://images.trvl-media.com/place/6360124/8b5bd5dc-d1e8-4f62-8efa-6c53ea07e013.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Veracruz [](https://expedia.com/Veracruz-Apartments.d6360124-aaApartments.Travel-Guide-Accommodation) ![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Colon [](https://expedia.com/Colon-Apartments.d601867-aaApartments.Travel-Guide-Accommodation) ## Our top choices for Panama apartments ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/362ba912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/737ceca4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Balcony](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/97c51ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/7cba0a34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panama [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) Bella Vista 7.6/10 Good (274 reviews) "Great location and good amenities for 1st time travellers Pool view is amazing... " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) nikita $136 nightly $149 total Apr 15 - Apr 16 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7fec4ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/c6184862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7d5bd8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/83a9c463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panamá by Boutique Apartments [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) Bella Vista 8.0/10 Very Good (81 reviews) "The stay was wonderful. Highly recommend. Great value. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Joseph $216 nightly $223 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/4fefbf57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/6445192b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/34a0b683.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Television](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/e5394f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) San Francisco 7.4/10 Good (180 reviews) "Would recommend this stay to anyone I know who is visiting Panama. We loved our room and also the check in process was easy! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrena $178 nightly $195 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Apartment, 3 Bedrooms (4B) | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/edb72763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (2C) | Balcony](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/273fe814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3B) | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/3372238d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1C) | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/dc6d18df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donovan By Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) Casco Viejo 8.2/10 Very Good (58 reviews) "Excellent room and good location. I did not receive security door or room code . Another hotel ckerk was able to reach then fir me at 8pm at night when i arrived. The place as a tiny sign in black that yu will miss. Otherwise great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tashi $133 nightly $143 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) ![Premier Suite, 1 King Bed, Garden View | Premium bedding, down comforters, individually decorated](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/f5f9cdd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Suite, 1 King Bed, Garden View | Living area | 43-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/91357f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Suite, 1 King Bed, Mountain View | Private kitchen | Fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/98fdcd03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/876ac108.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cielo by Villa Alejandro [](https://www.expedia.com/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) Boquete 9.4/10 Exceptional (106 reviews) "Everything was perfect! The room was comfortable and clean. The proximity to town was great!Communication with the hosts was excellent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lee $87 nightly $96 total May 3 - May 4 Total with taxes and fees [](https://www.expedia.com/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) ![Apartment (1D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/c78eb228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/569ccb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3D) | Private kitchen | Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/bf9924b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (3C) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/5b122387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa La Costa By Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) Casco Viejo 8.6/10 Excellent (27 reviews) "Location was beautiful. Cleanliness, not so good. The bed was rock hard with lumps and it was a very loud location, between a bar and the upstairs unit had a lot of people or parties. Great for the view, not so much for sleeping." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley $125 nightly $138 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) ![Apartment, 2 Bedrooms (1B) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/9e77777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1C) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/7717b8f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/4443ba1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1D) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/3f9c0f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Love by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) Casco Viejo 9.0/10 Wonderful (24 reviews) "Large, clean rooms, lots of space. Great bathroom. Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joette $140 nightly $154 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) ![Apartment, 2 Bedrooms (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/42608a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1C) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/50831da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/fc090f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/0447e43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Lefevre By Wynwood House [](https://www.expedia.com/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) Casco Viejo 9.4/10 Exceptional (11 reviews) "Staff was courteous, and the room was very beautiful. Would stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Selam $167 nightly $184 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/2fdde3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/4bc61653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (10C) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/ea03f013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) San Francisco 7.6/10 Good (35 reviews) "The place was clean nice an its comfortable an the view is to kill for amazing ‼️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Odaine $140 nightly $153 total May 3 - May 4 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Deluxe Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/0a2a9e4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Balcony](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/3c59dc38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/b8edc80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/6f82906f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Moderna by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) Casco Viejo 7.4/10 Good (45 reviews) "Great area. Close proximity to everything in Casco Viejo Water escapes from shower area to flood bathroom area while showering. Property could do with some landscaping. An overall fair experience. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aujae $114 nightly $125 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) ![Luxury Apartment | View from room](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/ead1ae24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/9bcaeb29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/f778c834.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/40000000/39140000/39130700/39130628/e6079dcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Surfside Beachfront Suites by Playa Caracol Resorts [](https://www.expedia.com/Punta-Chame-Hotels-Playa-Caracol-Residences-Vacation-Rental.h39130628.Hotel-Information) Punta Chame 7.6/10 Good (37 reviews) "Love this trip your own private paradise we are definitely going again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Solomon $195 nightly $215 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Punta-Chame-Hotels-Playa-Caracol-Residences-Vacation-Rental.h39130628.Hotel-Information) ![Comfort Suite, 1 Queen Bed with Sofa bed | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/6bfa829b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/9f96d68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/53efba5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Palma Experience [](https://www.expedia.com/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) Amador 8.4/10 Very Good (7 reviews) "All ways clean and ready to used ,no buddy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto $76 nightly $83 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) ![Superior Suite, 1 King Bed, Valley View, Mountainside | Private spa tub](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/6e28a490.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/4310cfd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed, Valley View, Mountainside | Laptop workspace, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/7ab9b645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed, Kitchenette, Valley View | Laptop workspace, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/13fd7cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Reina by Villa Alejandro [](https://www.expedia.com/Boquete-Hotels-Casa-Reina-By-Villa-Alejandro.h111493077.Hotel-Information) Boquete 8.6/10 Excellent (19 reviews) "Be aware the road, or trail more like it, to the hotel is very rough, only 1 lane in same areas. Check in took 15 minutes, with remote concierge. Views from balcony is great. Grounds are well kept. lots of small birds singing. Room is large and king bed is comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim $83 nightly $91 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Boquete-Hotels-Casa-Reina-By-Villa-Alejandro.h111493077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/94d2f2bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/600a3940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Private kitchen](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/ac3f0393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/7c635746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Apartment Piso 35 with City View [](https://www.expedia.com/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) Bella Vista 10/10 Exceptional (1 review) "I had a wonderful stay at this property The property was exceptionally clean, and the staff went above and beyond to make sure I felt welcome. Early check in. Highly recommended." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre [](https://www.expedia.com/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) ![Apartment, 2 Bedrooms (CC2A) | Premium bedding, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/a1353e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/w2000h1310x0y0-5cea16ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC2B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/86dc292b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1A) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/bb5e8873.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Contemporanea by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) Casco Viejo 8.2/10 Very Good (22 reviews) "Cute place, well located. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Stephanie $177 nightly $192 total Apr 15 - Apr 16 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) ![Apartment, 3 Bedrooms (CM5) | Living room | 55-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/67865bff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/1a0cf4a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/932f3bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CM1) | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/776d053a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Mallet by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) Casco Viejo 9.8/10 Exceptional (27 reviews) "It was amazing! Staff was easy to contact. Very clean apartment and great location with shops and restuarants nearby. Patio with chairs to overlook the area. Couldnt have had a better stay. Excellent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chisina [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/7731b155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/5ace70c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/16f7b9a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/b23e7852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Apartamento [](https://www.expedia.com/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information) Bella Vista 9.2/10 Wonderful (17 reviews) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jimmy Lee $128 nightly $141 total Apr 22 - Apr 23 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/w1023h982x0y0-cbf9c42c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/f77ce1e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/8b11030c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/0a183484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Apartment With Private Beach And Sea View [](https://www.expedia.com/Veracruz-Hotels-Luxury-Apartment-With-Private-Beach-And-Sea-View.h83097642.Hotel-Information) Panama City 10/10 Exceptional (13 reviews) "Property was beautiful and really enjoyed the Pearl Club" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra C. [](https://www.expedia.com/Veracruz-Hotels-Luxury-Apartment-With-Private-Beach-And-Sea-View.h83097642.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/fe2a6d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/cf6fd2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/53709432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/e3d1e67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza Catedral Views by AcoModo [](https://www.expedia.com/Panama-City-Hotels-2-Bdr-2-Bthr-Apartment-In-Casco-Viejo-Near-Sites-Of-Interest.h106499044.Hotel-Information) Casco Viejo 8.0/10 Very Good (4 reviews) "We came back after 3 weeks of our first stay. We loved this place so much that we could not resist to use it again. We used the stove and all kitchen facilities this time and we enjoyed our stay even more. Having breakfast in the appartment with the central park view is just priceless.I traveled with my mother of 80 years old and although I was concerned about the stairs, this was never an issue. This place is clean, safe, has a wonderful location if you use Uber to go around and it... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lilliam V. [](https://www.expedia.com/Panama-City-Hotels-2-Bdr-2-Bthr-Apartment-In-Casco-Viejo-Near-Sites-Of-Interest.h106499044.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/335c377d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/6ab36353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/cbf3f070.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/b24b1e03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Location, 2 bed, 2baths, High Speed Internet [](https://www.expedia.com/Panama-City-Hotels-Best-Location.h90707371.Hotel-Information) Bella Vista 9.2/10 Wonderful (9 reviews) "City hop on hop off is just around the corner." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nilesh J. [](https://www.expedia.com/Panama-City-Hotels-Best-Location.h90707371.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-19&endDate=2026-04-20®ionId=142&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Villas [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-04&d1=2026-07-04&endDate=2026-07-07&d2=2026-07-07&lodging=VILLA) Cabins [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-04&d1=2026-07-04&endDate=2026-07-07&d2=2026-07-07&lodging=CABIN) Apartments [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-04&d1=2026-07-04&endDate=2026-07-07&d2=2026-07-07&lodging=APARTMENT) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-04&d1=2026-07-04&endDate=2026-07-07&d2=2026-07-07&lodging=VACATION_HOME) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-04&d1=2026-07-04&endDate=2026-07-07&d2=2026-07-07&lodging=APART_HOTEL) Condos [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-04&d1=2026-07-04&endDate=2026-07-07&d2=2026-07-07&lodging=CONDO) Houseboats [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-04&d1=2026-07-04&endDate=2026-07-07&d2=2026-07-07&lodging=HOUSE_BOAT) Cottages [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-04&d1=2026-07-04&endDate=2026-07-07&d2=2026-07-07&lodging=COTTAGE) Chalets [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-07-04&d1=2026-07-04&endDate=2026-07-07&d2=2026-07-07&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanama-Apartments.d142-aaApartments.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanama-Apartments.d142-aaApartments.Travel-Guide-Accommodation) ## Top Panama Hotel Reviews ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Breakfast was exceptional " [](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Ramada Plaza by Wyndham Panama Punta Pacifica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b_y.jpg) ### Ramada Plaza by Wyndham Panama Punta Pacifica 10/10 Excellent "Reception desk was very accommodating and helped me check in earlier than 3:00 pm as I was visibly exhausted by the commute from the airport to the hotel. Breakfast was good, byt the yogurt…. (to die for with REAL FRESH strawberries )" [](https://expedia.com/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "10/10 " [](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "My stay was the best!" [](https://expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Everything was excellent was close to the subway station " [](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 8/10 Good "Poor at 6am" [](https://expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Very clean room, excellent staff, breakfast wonderful and amazing shopping. " [](https://expedia.com/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg) ### The Executive Hotel 8/10 Good "The location of the property is great for getting around Panama especially by the bus or metro. Staff is very friendly and helpful even with a language barrier - I don't know much Spanish. Clean rooms with good amenities. Good buffet breakfast." [](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "Was excellent all the staff " [](https://expedia.com/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ## Find out more about Panama ## Panama Apartments information | Number of reviews | 866 | | ----------------- | --------------- | | Accommodation | 1681 Apartments | | Lowest Price | $83 | | Highest Price | $286 | ## Explore a world of travel with Expedia - Lodging - Packages - Cars - [Hotels near Sante Fe National Park ](https://www.expedia.com/Sante-Fe-National-Park-Hotels.0-l553248635976022317-0.Travel-Guide-Filter-Hotels) - [Sante Fe National Park ](https://www.expedia.com/Sante-Fe-National-Park-Panama.d553248635976022317.Vacation-Attraction) - [Car rentals near Sante Fe National Park ](https://www.expedia.com/Car-Rentals-In-Sante-Fe-National-Park.d553248635976022317.Car-Rental-Guide)