Title: Best Apartments in Panama for Your Vacation from $96 | Expedia.com [Panama Travel Guide](https://expedia.com/Panama.dx142)[Panama Hotels](https://expedia.com/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Things to do in Panama](https://expedia.com/Things-To-Do-In-Panama.d142.Travel-Guide-Activities)[Car Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides) ![Panama featuring landscape views, tropical scenes and island images](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy ![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 17 - Jul 19](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Cities in Panama ![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.com/Panama-City-Apartments.d2897-aaApartments.Travel-Guide-Accommodation) ![ISLA COLON BOCAS DEL TORO](https://images.trvl-media.com/place/6023445/f17b18cc-4a72-405d-ab41-dfd48c15b97d.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Bocas del Toro [](https://expedia.com/Bocas-Del-Toro-Apartments.d6023445-aaApartments.Travel-Guide-Accommodation) ![Idyllic Sunset at Playa Blanca, Panama](https://images.trvl-media.com/place/6246042/058a4e01-e481-4197-9791-26c53b4ee917.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Rio Hato [](https://expedia.com/Rio-Hato-Apartments.d6246042-aaApartments.Travel-Guide-Accommodation) ![Sunrise with a view at Volcán Barú in Panama](https://images.trvl-media.com/place/500194/a9fdba1c-ad36-4683-90ac-2cdb584e103b.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Boquete [](https://expedia.com/Boquete-Apartments.d500194-aaApartments.Travel-Guide-Accommodation) ![Traditional dances of the state of Veracruz Mexico, typical clothes.](https://images.trvl-media.com/place/6360124/8b5bd5dc-d1e8-4f62-8efa-6c53ea07e013.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Veracruz [](https://expedia.com/Veracruz-Apartments.d6360124-aaApartments.Travel-Guide-Accommodation) ![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Colon [](https://expedia.com/Colon-Apartments.d601867-aaApartments.Travel-Guide-Accommodation) ## Our top choices for Panama apartments ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/362ba912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Balcony](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/97c51ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/7cba0a34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/a4be5f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panama [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) Bella Vista 7.6/10 Good (267 reviews) "Great central location! Great price. Clean. Nice pool." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Armin $129 nightly $141 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7fec4ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/83a9c463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/c6184862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/2f5f574e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panamá by Boutique Apartments [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) Bella Vista 8.0/10 Very Good (72 reviews) "Great Apartment clean, excellent ocean view. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $216 nightly $223 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/4fefbf57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Television](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/e5394f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/6445192b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/34a0b683.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) San Francisco 7.6/10 Good (174 reviews) "The best place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julio $178 nightly $195 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Apartment, 3 Bedrooms (4B) | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/edb72763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms (4B) | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/17257b2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1C) | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/dc6d18df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3B) | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/3372238d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donovan By Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) Casco Viejo 8.2/10 Very Good (57 reviews) "Excellent room and good location. I did not receive security door or room code . Another hotel ckerk was able to reach then fir me at 8pm at night when i arrived. The place as a tiny sign in black that yu will miss. Otherwise great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tashi $115 nightly $123 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) ![Premier Suite, 1 King Bed, Garden View | Premium bedding, down comforters, individually decorated](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/f5f9cdd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/876ac108.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Suite, 1 King Bed, Mountain View | Private kitchen | Fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/98fdcd03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Suite, 1 King Bed, Garden View | Living area | 43-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/91357f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cielo by Villa Alejandro [](https://www.expedia.com/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) Boquete 9.4/10 Exceptional (103 reviews) "Everything was perfect! The room was comfortable and clean. The proximity to town was great!Communication with the hosts was excellent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lee $107 nightly $118 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) ![Apartment (1D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/c78eb228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3D) | Private kitchen | Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/bf9924b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (3C) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/5b122387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/1cdad385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa La Costa By Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) Casco Viejo 8.4/10 Very Good (26 reviews) "Great location. At the border of renovated areas but an extremely go deal for this great property. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William $129 nightly $143 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) ![Apartment, 2 Bedrooms (1B) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/9e77777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Private kitchen | Coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/04577a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1D) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/3f9c0f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1C) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/7717b8f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Love by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) Casco Viejo 9.0/10 Wonderful (24 reviews) "Large, clean rooms, lots of space. Great bathroom. Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joette $109 nightly $120 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (10C) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/ea03f013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/f99400a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/4bc61653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) San Francisco 7.6/10 Good (35 reviews) "The place was clean nice an its comfortable an the view is to kill for amazing ‼️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Odaine $133 nightly $146 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Apartment, 2 Bedrooms (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/42608a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1C) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/50831da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/9a31f88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/0447e43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Lefevre By Wynwood House [](https://www.expedia.com/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) Casco Viejo 9.2/10 Wonderful (9 reviews) "Staff was courteous, and the room was very beautiful. Would stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Selam $165 nightly $182 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) ![Deluxe Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/0a2a9e4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Balcony](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/3c59dc38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97957e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Soundproofing, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/b8edc80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Moderna by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) Casco Viejo 7.4/10 Good (45 reviews) "Great area. Close proximity to everything in Casco Viejo Water escapes from shower area to flood bathroom area while showering. Property could do with some landscaping. An overall fair experience. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aujae $119 nightly $131 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) ![Comfort Suite, 1 Queen Bed with Sofa bed | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/2462f537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/53efba5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/6bfa829b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Palma Aparta Suite [](https://www.expedia.com/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) Amador 8.4/10 Very Good (7 reviews) "All ways clean and ready to used ,no buddy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto $88 nightly $96 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) ![Superior Suite, 1 King Bed, Valley View, Mountainside | Private spa tub](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/6e28a490.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/4310cfd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed, Valley View, Mountainside | Laptop workspace, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/7ab9b645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed, Kitchenette, Valley View | Laptop workspace, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/112000000/111500000/111493100/111493077/13fd7cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Reina by Villa Alejandro [](https://www.expedia.com/Boquete-Hotels-Casa-Reina-By-Villa-Alejandro.h111493077.Hotel-Information) Boquete 8.6/10 Excellent (19 reviews) "The property is outside of the town proper, so is quiet and it is possible to see wildlife. The room was extremely clean and comfortable, and the staff was welcoming and friendly. The view from the balcony was amazing!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Catherine $92 nightly $102 total Apr 22 - Apr 23 Total with taxes and fees [](https://www.expedia.com/Boquete-Hotels-Casa-Reina-By-Villa-Alejandro.h111493077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/94d2f2bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/7c635746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/600a3940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Private kitchen](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/ac3f0393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Apartment Piso 35 with City View [](https://www.expedia.com/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) Bella Vista 10/10 Exceptional (1 review) "I had a wonderful stay at this property The property was exceptionally clean, and the staff went above and beyond to make sure I felt welcome. Early check in. Highly recommended." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre [](https://www.expedia.com/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) ![Apartment, 2 Bedrooms (CC2A) | Premium bedding, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/a1353e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1A) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/bb5e8873.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC4A) | Balcony](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/90de29d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1B) | Living area | 100-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/w2000h1310x0y0-5cea16ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Contemporanea by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) Casco Viejo 8.2/10 Very Good (21 reviews) "Cute place, well located. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Stephanie $157 nightly $170 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/7731b155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/5ace70c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/16f7b9a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/95000000/94630000/94627400/94627351/b23e7852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Apartamento [](https://www.expedia.com/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information) Bella Vista 9.2/10 Wonderful (17 reviews) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jimmy Lee $128 nightly $141 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Yoo-Apartamento.h94627351.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/w1023h982x0y0-cbf9c42c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/698dc46b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/f77ce1e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83100000/83097700/83097642/8b11030c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Apartment With Private Beach And Sea View [](https://www.expedia.com/Veracruz-Hotels-Luxury-Apartment-With-Private-Beach-And-Sea-View.h83097642.Hotel-Information) Panama City 10/10 Exceptional (13 reviews) "Property was beautiful and really enjoyed the Pearl Club" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra C. [](https://www.expedia.com/Veracruz-Hotels-Luxury-Apartment-With-Private-Beach-And-Sea-View.h83097642.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/fe2a6d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/53709432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/e3d1e67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106500000/106499100/106499044/cf6fd2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza Catedral Views by AcoModo [](https://www.expedia.com/Panama-City-Hotels-2-Bdr-2-Bthr-Apartment-In-Casco-Viejo-Near-Sites-Of-Interest.h106499044.Hotel-Information) Casco Viejo 10/10 Exceptional (3 reviews) "We came back after 3 weeks of our first stay. We loved this place so much that we could not resist to use it again. We used the stove and all kitchen facilities this time and we enjoyed our stay even more. Having breakfast in the appartment with the central park view is just priceless.I traveled with my mother of 80 years old and although I was concerned about the stairs, this was never an issue. This place is clean, safe, has a wonderful location if you use Uber to go around and it... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lilliam V. $153 nightly $153 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-2-Bdr-2-Bthr-Apartment-In-Casco-Viejo-Near-Sites-Of-Interest.h106499044.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/335c377d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/b0b19c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/cbf3f070.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/91000000/90710000/90707400/90707371/6ab36353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Location, 2 bed, 2baths, High Speed Internet [](https://www.expedia.com/Panama-City-Hotels-Best-Location.h90707371.Hotel-Information) Bella Vista 9.2/10 Wonderful (9 reviews) "City hop on hop off is just around the corner." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nilesh J. $145 nightly $145 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Best-Location.h90707371.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/124000000/123400000/123391100/123391056/9be05c26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/124000000/123400000/123391100/123391056/561c9910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/124000000/123400000/123391100/123391056/149e0043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/124000000/123400000/123391100/123391056/f1779383.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 2br Close to Panama Old Town [](https://www.expedia.com/Panama-City-Hotels-Cozy-2br-Close-To-Panama-Old-Town.h123391056.Hotel-Information) San Francisco $257 nightly $257 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Cozy-2br-Close-To-Panama-Old-Town.h123391056.Hotel-Information) ![Apartment (10D) | Balcony](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/50a5594d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (10D) | Living area | 55-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/61f602f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/6c30f1dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Elite Apartment (08D) | Living area | 55-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/8545438c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Francisco by Wynwood House [](https://www.expedia.com/Panama-City-Hotels-Living-By-Wynwood-House.h100525493.Hotel-Information) San Francisco 9.2/10 Wonderful (56 reviews) "Clean and walkable location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamera [](https://www.expedia.com/Panama-City-Hotels-Living-By-Wynwood-House.h100525493.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-06&endDate=2026-04-07®ionId=142&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Villas [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=VILLA) Cabins [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=CABIN) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=VACATION_HOME) Apartments [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=APARTMENT) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=APART_HOTEL) Houseboats [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=HOUSE_BOAT) Condos [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=CONDO) Cottages [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=COTTAGE) Chalets [](https://www.expedia.com/Hotel-Search?destination=Panama®ionId=142&latLong=8.537972%2C-80.782123&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanama-Apartments.d142-aaApartments.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanama-Apartments.d142-aaApartments.Travel-Guide-Accommodation) ## Top Panama Hotel Reviews ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 2/10 Terrible "This hotel was a nightmare. I arrived at Panama City from Ecuador at 8:30pm, but NO Shuttle was available as they advertised on Expedia, and even worse, there was no one to answer the phone at all. I emailed, texted, and called the hotel right after I received the book confirmation from Expedia and the day BEFORE my arrival because it was my first time to visit Panama. The property NEVER responded, so I had to call Expedia at the airport after my arrival. Long story short, Expedia could NOT reach them, either, and told me to take Taxi to get to the hotel almost midnight. I did not know whether there was anyone to check in at that time, so I had to request to cancel the booking and get refund. I am very disappointed with Expedia's listing recently because I had a few unpleasant experiences with bookings on Expedia. I wish Expedia had a system to validate the listings and knew the properties' advertisement is honest." [](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 6/10 Okay "The shuttle runs a specific time from the hotel (at every hour o'clock) and from the hotel ()" [](https://expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg) ### The Executive Hotel 10/10 Excellent "Great find! So happy with the hotel" [](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The breakfast was great, I only wish it opened at 6am (even in limited form) as we were only able to fully partake 1/3 days that we were there because of excursions and flights. Room was clean and comfortable. Would have liked to have an extra pillow available instead of only 3 on the bed. Views were great and the pool area had fun vibes!" [](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Hotel Ojos del Rio](https://images.trvl-media.com/lodging/11000000/10540000/10538500/10538417/dddd2643_y.jpg) ### Hotel Ojos del Rio 2/10 Terrible "Terrible on hair on the bed toilet seat was broken bed linen was old and yellow supposed to be white this places is an old building that needs loss of work and repair very disappoint I walked out of there and didn’t go a refund 3/14/2026 p" [](https://expedia.com/Panama-City-Hotels-Hotel-Ojos-Del-Rio.h10538417.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Clean rooms, beautiful propery " [](https://expedia.com/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/bd4cfae6_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "The BEST!" [](https://expedia.com/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 6/10 Okay "The spa was clean and relaxing " [](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "=)" [](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ## Price trends for hotels in Panama | Less expensive | More expensive | Next month | | -------------- | -------------- | ---------- | | May | April | $112 | | Month | Price | | --------- | ----- | | January | $92 | | February | $91 | | March | $91 | | April | $112 | | May | $89 | | June | $99 | | July | $99 | | August | $99 | | September | $97 | | October | $101 | | November | $91 | | December | $107 | Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed Apartments in Panama. Select dates and complete search for nightly totals inclusive of taxes and fees. ## Find out more about Panama ## Panama Apartments information | Number of reviews | 958 | | ----------------- | --------------- | | Accommodation | 1681 Apartments | | Lowest Price | $96 | | Highest Price | $257 | ## Explore a world of travel with Expedia - Lodging - Packages - Cars - [Hotels near Sante Fe National Park ](https://www.expedia.com/Sante-Fe-National-Park-Hotels.0-l553248635976022317-0.Travel-Guide-Filter-Hotels) - [Sante Fe National Park ](https://www.expedia.com/Sante-Fe-National-Park-Panama.d553248635976022317.Vacation-Attraction) - [Car rentals near Sante Fe National Park ](https://www.expedia.com/Car-Rentals-In-Sante-Fe-National-Park.d553248635976022317.Car-Rental-Guide)