Resorts & Hotels with Spas in Panama from $97

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Check availability on Panama Resorts & Hotels with Spas

Pick from 275 Panama Resorts & Hotels with Spas with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Panama hotels with a spa

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 star property
8.8 out of 10, Excellent, (988)
"2nd stay at Sortis Hotel in Panama. Never disappoints. Breakfast Buffett incredible and staff pleasant and attentive! Will stay there again!"
$150 nightly
The price is $165
Sep 18 - Sep 19
Total with taxes and fees
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2228)
"Great hotel near the airport "
$116 nightly
The price is $128
Sep 20 - Sep 21
Total with taxes and fees
Crowne Plaza Panama Airport by IHG

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (607)
"Everything at this hotel was immaculate. From the service, to the food, the entire team was incredible and made our first time in Panama welcome."
$216 nightly
The price is $238
Oct 3 - Oct 4
Total with taxes and fees
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Marriott Panama Hotel

4.0 star property
9.0 out of 10, Wonderful, (1002)
"Had an amazing stay with my family "
$127 nightly
The price is $139
Sep 21 - Sep 22
Total with taxes and fees
Marriott Panama Hotel

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1006)
"A lovely hotel and excellent food and rooms and service. "
$176 nightly
The price is $194
Oct 18 - Oct 19
Total with taxes and fees
Bristol Panama, a Registry Collection Hotel

W Panama

5.0 star property
9.0 out of 10, Wonderful, (1005)
"Great hotel "
$179 nightly
The price is $197
Oct 17 - Oct 18
Total with taxes and fees
W Panama

Radisson Colon 2,000 Hotel & Casino

4.0 star property
8.2 out of 10, Very Good, (783)
"Always a great choice for stay!"
$88 nightly
The price is $97
Oct 3 - Oct 4
Total with taxes and fees
Radisson Colon 2,000 Hotel & Casino

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (508)
"Great stay"
$293 nightly
The price is $322
Oct 1 - Oct 2
Total with taxes and fees
Sofitel Legend Casco Viejo, Panama City

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (947)
"Great staff and beautiful hotel. Will definitely stay again!"
$134 nightly
The price is $148
Sep 26 - Sep 27
Total with taxes and fees
Sheraton Grand Panama

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1002)
"Great property You don’t go wrong Amenities are great Location is perfect area safe and walkable rooms are nice large clean modern "
$220 nightly
The price is $242
Oct 11 - Oct 12
Total with taxes and fees
Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews