Title: Panama Resorts & Hotels with Spas from $120 - Fully Refundable Options - Expedia.com

[Panama Travel Guide](https://expedia.com/Panama.dx142)[Panama Hotels](https://expedia.com/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Car Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides)

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## Top Cities in Panama

![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Panama City

[](https://expedia.com/Panama-City-Hotels-Spa-Hotel.0-0-d2897-tSpaHotel.Travel-Guide-Filter-Hotels)

![ISLA COLON BOCAS DEL TORO](https://images.trvl-media.com/place/6023445/f17b18cc-4a72-405d-ab41-dfd48c15b97d.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Bocas del Toro

[](https://expedia.com/Bocas-Del-Toro-Hotels-Spa-Hotel.0-0-d6023445-tSpaHotel.Travel-Guide-Filter-Hotels)

![Idyllic Sunset at Playa Blanca, Panama](https://images.trvl-media.com/place/6246042/058a4e01-e481-4197-9791-26c53b4ee917.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Rio Hato

[](https://expedia.com/Rio-Hato-Hotels-Spa-Hotel.0-0-d6246042-tSpaHotel.Travel-Guide-Filter-Hotels)

![Sunrise with a view at Volcán Barú in Panama](https://images.trvl-media.com/place/500194/a9fdba1c-ad36-4683-90ac-2cdb584e103b.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Boquete

[](https://expedia.com/Boquete-Hotels-Spa-Hotel.0-0-d500194-tSpaHotel.Travel-Guide-Filter-Hotels)

![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Colon

[](https://expedia.com/Colon-Hotels-Spa-Hotel.0-0-d601867-tSpaHotel.Travel-Guide-Filter-Hotels)

![Panoramic view of El Valle de Anton town surrounded by mountains in Panama](https://images.trvl-media.com/place/6053180/c16502d5-7d2c-4d59-91a1-745c940461bf.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### El Valle de Anton

[](https://expedia.com/El-Valle-De-Anton-Hotels-Spa-Hotel.0-0-d6053180-tSpaHotel.Travel-Guide-Filter-Hotels)

## Check availability on Panama Resorts & Hotels with Spas

Tonight

[Apr 6 - Apr 7](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-06&endDate=2026-04-07&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Apr 7 - Apr 8](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-07&endDate=2026-04-08&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-10&endDate=2026-04-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-17&endDate=2026-04-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Panama hotels with a spa

![Steam room, body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/9e776b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/ab95ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/86e96c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

[](https://www.expedia.com/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,000 reviews)

- Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.

$169 nightly

$186 total

May 2 - May 3

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/757e8465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/5f648ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/2f37bae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Crowne Plaza Panama Airport by IHG

[](https://www.expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)

Tocumen

8.6/10

Excellent

(2,495 reviews)

$133 nightly

$146 total

Apr 28 - Apr 29

Total with taxes and fees

[](https://www.expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)

![Couples treatment rooms, steam room, Turkish bath, body treatments](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/0b681c03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c579d87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ea9ff933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

[](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information)

Juan Diaz

9.6/10

Exceptional

(685 reviews)

- Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape.

$269 nightly

$296 total

May 2 - May 3

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information)

![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/860def94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marriott Panama Hotel

[](https://www.expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

Panama City

9.0/10

Wonderful

(1,002 reviews)

$152 nightly

$167 total

Apr 25 - Apr 26

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/80d0e2a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/620cc150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/86dd447e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bristol Panama, a Registry Collection Hotel

[](https://www.expedia.com/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information)

Bella Vista

9.4/10

Exceptional

(1,008 reviews)

- Immerse in luxurious tranquility at this Art Deco hotel with 6 treatment rooms and an outdoor pool for a rejuvenating retreat.

$194 nightly

$213 total

May 7 - May 8

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/79004c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, local cuisine](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/8f2104c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Urban Suite,1 King, Partial City view | In-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/0b373179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### W Panama

[](https://www.expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,009 reviews)

- Revitalize at this luxury hotel with three hot tubs, yoga classes, and rejuvenating massage services in a serene garden setting.

$239 nightly

$263 total

May 2 - May 3

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Couples treatment rooms, Turkish bath, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/1a303895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/e77a4c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/53f67005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Radisson Colon 2,000 Hotel & Casino

[](https://www.expedia.com/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information)

Barrio Sur

8.2/10

Very Good

(892 reviews)

- Rejuvenate at this waterfront hotel featuring couples spa treatments, an outdoor pool, and hot stone massages for a serene escape.

$109 nightly

$120 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information)

![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/8d3d5a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/88416317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, swim-up bar, poolside bar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/83d16a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ccd122a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sofitel Legend Casco Viejo, Panama City 

[](https://www.expedia.com/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information)

Casco Viejo

9.8/10

Exceptional

(630 reviews)

- Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.

$347 nightly

$381 total

Apr 27 - Apr 28

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information)

![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/f95b4a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/58ea7ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (PAB 21 per person)](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/22409c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sheraton Grand Panama

[](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

San Francisco

8.6/10

Excellent

(1,008 reviews)

- Immerse in tranquility at this Art Deco resort with two treatment rooms for couples and a Turkish bath, where expert spa therapists await.

$134 nightly

$148 total

May 1 - May 2

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/124fc0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/37502420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch served; American cuisine](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/eb1560c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Panama

[](https://www.expedia.com/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,002 reviews)

- Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.

$233 nightly

$256 total

May 1 - May 2

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Panama Hotel Reviews

![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg)

### Waymore Hotel Spa & Casino

10/10 Excellent

"It's very homly . Very relaxing "

[](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information)

![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg)

### Sheraton Grand Panama

10/10 Excellent

"Everything was excellent Highly recommend this property "

[](https://expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg)

### Dreams Playa Bonita Panama - All Inclusive

4/10 Poor

"The rooms needs upgrading "

[](https://expedia.com/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information)

![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg)

### JW Marriott Panama

8/10 Good

"Modern facilities that is clean. Elevators suboptimal, with potential long waits during busy hours and stopping at multiple levels inexplicably with no one coming on or off. Setup of shower and toilet is very strange."

[](https://expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information)

![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg)

### The Executive Hotel

10/10 Excellent

"Good location and value"

[](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information)

![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg)

### W Panama

8/10 Good

"I think some items in the rooms could be updated "

[](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Hyatt Regency Panama City](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/616200e0_y.jpg)

### Hyatt Regency Panama City

10/10 Excellent

"Very nice and clean hotel the manager in the front was very good"

[](https://expedia.com/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information)

![Renaissance Panama City Hotel ](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/4235e7f0_y.jpg)

### Renaissance Panama City Hotel 

10/10 Excellent

"Great location close to downtown, in a quite and nice area. "

[](https://expedia.com/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information)

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg)

### Hotel Riu Plaza Panama

8/10 Good

"Breakfast was really good 5 stars only negative was the pool bar and face cloths. Other than that property is beyond nice "

[](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

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