Title: Panama Resorts & Hotels with Spas from $120 - Fully Refundable Options - Expedia.com

[Panama Travel Guide](https://expedia.com/Panama.dx142)[Panama Hotels](https://expedia.com/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Car Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides)

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## Top Cities in Panama

![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Panama City

[](https://expedia.com/Panama-City-Hotels-Spa-Hotel.0-0-d2897-tSpaHotel.Travel-Guide-Filter-Hotels)

![ISLA COLON BOCAS DEL TORO](https://images.trvl-media.com/place/6023445/f17b18cc-4a72-405d-ab41-dfd48c15b97d.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Bocas del Toro

[](https://expedia.com/Bocas-Del-Toro-Hotels-Spa-Hotel.0-0-d6023445-tSpaHotel.Travel-Guide-Filter-Hotels)

![Idyllic Sunset at Playa Blanca, Panama](https://images.trvl-media.com/place/6246042/058a4e01-e481-4197-9791-26c53b4ee917.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Rio Hato

[](https://expedia.com/Rio-Hato-Hotels-Spa-Hotel.0-0-d6246042-tSpaHotel.Travel-Guide-Filter-Hotels)

![Sunrise with a view at Volcán Barú in Panama](https://images.trvl-media.com/place/500194/a9fdba1c-ad36-4683-90ac-2cdb584e103b.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Boquete

[](https://expedia.com/Boquete-Hotels-Spa-Hotel.0-0-d500194-tSpaHotel.Travel-Guide-Filter-Hotels)

![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Colon

[](https://expedia.com/Colon-Hotels-Spa-Hotel.0-0-d601867-tSpaHotel.Travel-Guide-Filter-Hotels)

![Panoramic view of El Valle de Anton town surrounded by mountains in Panama](https://images.trvl-media.com/place/6053180/c16502d5-7d2c-4d59-91a1-745c940461bf.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### El Valle de Anton

[](https://expedia.com/El-Valle-De-Anton-Hotels-Spa-Hotel.0-0-d6053180-tSpaHotel.Travel-Guide-Filter-Hotels)

## Check availability on Panama Resorts & Hotels with Spas

Tonight

[Mar 28 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-03-28&endDate=2026-03-29&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 29 - Mar 30](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-03-29&endDate=2026-03-30&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-03&endDate=2026-04-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-10&endDate=2026-04-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Panama hotels with a spa

![Steam room, body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/9e776b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/86e96c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/ab95ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

[](https://www.expedia.com/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,000 reviews)

"The hotel in general was great and the restaurants were excellent."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Hazem

$169 nightly

$186 total

Apr 4 - Apr 5

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/757e8465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/5f648ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/2f37bae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Crowne Plaza Panama Airport by IHG

[](https://www.expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)

Tocumen

8.6/10

Excellent

(2,486 reviews)

"Very clean and comfortable stay, beautiful lobby and restaurant."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

EL Heru

$127 nightly

$140 total

Apr 27 - Apr 28

Total with taxes and fees

[](https://www.expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)

![Couples treatment rooms, steam room, Turkish bath, body treatments](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/0b681c03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c579d87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ea9ff933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

[](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information)

Juan Diaz

9.6/10

Exceptional

(680 reviews)

"As usual the stay was amazing in this hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jose

$249 nightly

$274 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information)

![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/860def94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/7bb8f38a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marriott Panama Hotel

[](https://www.expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

Panama City

9.0/10

Wonderful

(1,000 reviews)

"Had a great time. This hotel is great "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Genette

$161 nightly

$177 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/80d0e2a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/620cc150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/86dd447e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bristol Panama, a Registry Collection Hotel

[](https://www.expedia.com/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information)

Bella Vista

9.4/10

Exceptional

(1,001 reviews)

"Excellent Spa."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

$194 nightly

$213 total

Mar 31 - Apr 1

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/79004c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Urban Suite,1 King, Partial City view | In-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/0b373179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/8f2104c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, local cuisine](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### W Panama

[](https://www.expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

Bella Vista

9.0/10

Wonderful

(1,004 reviews)

"Very nice and cozy hotel I like this place a lot"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shahram Sean

$319 nightly

$351 total

Apr 3 - Apr 4

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Couples treatment rooms, Turkish bath, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/e77a4c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/1a303895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/665077af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Radisson Colon 2,000 Hotel & Casino

[](https://www.expedia.com/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information)

Barrio Sur

8.2/10

Very Good

(884 reviews)

"Friendly staff, great for cruises departing from colon"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kathy-Ann M

$109 nightly

$120 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information)

![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/8d3d5a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/c28c4592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ccd122a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/88416317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sofitel Legend Casco Viejo, Panama City 

[](https://www.expedia.com/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information)

Casco Viejo

9.8/10

Exceptional

(624 reviews)

"Had a lovely stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Olly

$351 nightly

$386 total

Apr 27 - Apr 28

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information)

![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/f95b4a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/c780324d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/58ea7ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (PAB 21 per person)](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sheraton Grand Panama

[](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

San Francisco

8.6/10

Excellent

(1,005 reviews)

"Breakfast was great , clean room and staff was nice "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Pauline

$140 nightly

$153 total

Apr 4 - Apr 5

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/124fc0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch served; American cuisine](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch served; American cuisine](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/eb1560c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Panama

[](https://www.expedia.com/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,002 reviews)

"Attentive and polite staff Good views Very clean"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

rich steven

$237 nightly

$261 total

Apr 25 - Apr 26

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information)

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## Top Panama Hotel Reviews

![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg)

### Courtyard by Marriott Panama Multiplaza Mall

8/10 Good

"Great hotel and good customer services "

[](https://expedia.com/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information)

![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg)

### Waymore Hotel Spa & Casino

10/10 Excellent

"Great buffet"

[](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information)

![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg)

### Principe Hotel and Suites

10/10 Excellent

"Thank you for the nice stay. We’re looking forward to returning this weekend. This will be easy as our go-to place when traveling through Panama City for overnights. Thanks for a decent room at a reasonable price. Breakfast is not in the hotel but a 30 foot walk to next door. Just for those expecting that to be in the hotel, it’s only available next door and give yourself some time to get it as the service is a bit slower for hot meals."

[](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information)

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg)

### Hotel Riu Plaza Panama

10/10 Excellent

"Amazing breakfast selection a large variety very friendly and pleasant staff"

[](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

![Ramada Plaza by Wyndham Panama Punta Pacifica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b_y.jpg)

### Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent

"The staff was excellent and the overall facility was very clean and inviting "

[](https://expedia.com/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information)

![Hotel Riu Playa Blanca - All Inclusive](https://images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/737d5dbd_y.jpg)

### Hotel Riu Playa Blanca - All Inclusive

10/10 Excellent

"Great resort with fantastic activities! The beach was beautiful with plenty of loungers around both the beach area and pools. Nice rooms and friendly staff. "

[](https://expedia.com/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information)

![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg)

### Sheraton Grand Panama

10/10 Excellent

"the hotel was close to both the airport and the places of interest"

[](https://expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e50f6f0f_y.jpg)

### The Westin Playa Bonita Panama

10/10 Excellent

"Property is beautiful, just a small tad dated but lovely nonetheless. That’s the reason for the 4 stars. The buffet breakfast is phenomenal, the restaurants onsite are fantastic. All of the food was great! The amenities were amazing! Hands down a magnificent resort on the west side of Panama. One slight warning, the traffic to the hotel is ridiculous, most times of day. If you are planning on staying out, you are fine, but if planning to go back and forth to Panama City, be forewarned. Could take three times the time due to the traffic to cross the bridge. "

[](https://expedia.com/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information)

![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg)

### The Executive Hotel

8/10 Good

"I didn't stay that long, only a few hours, so I didn't have time to go explore the surroundings. "

[](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information)

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