Title: Panama Resorts & Hotels with Spas from $120 - Fully Refundable Options - Expedia.com

[Panama Travel Guide](https://expedia.com/Panama.dx142)[Panama Hotels](https://expedia.com/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Car Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides)

![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by PhotoJoy

![](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

## Top Cities in Panama

![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Panama City

[](https://expedia.com/Panama-City-Hotels-Spa-Hotel.0-0-d2897-tSpaHotel.Travel-Guide-Filter-Hotels)

![ISLA COLON BOCAS DEL TORO](https://images.trvl-media.com/place/6023445/f17b18cc-4a72-405d-ab41-dfd48c15b97d.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Bocas del Toro

[](https://expedia.com/Bocas-Del-Toro-Hotels-Spa-Hotel.0-0-d6023445-tSpaHotel.Travel-Guide-Filter-Hotels)

![Idyllic Sunset at Playa Blanca, Panama](https://images.trvl-media.com/place/6246042/058a4e01-e481-4197-9791-26c53b4ee917.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Rio Hato

[](https://expedia.com/Rio-Hato-Hotels-Spa-Hotel.0-0-d6246042-tSpaHotel.Travel-Guide-Filter-Hotels)

![Sunrise with a view at Volcán Barú in Panama](https://images.trvl-media.com/place/500194/a9fdba1c-ad36-4683-90ac-2cdb584e103b.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Boquete

[](https://expedia.com/Boquete-Hotels-Spa-Hotel.0-0-d500194-tSpaHotel.Travel-Guide-Filter-Hotels)

![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Colon

[](https://expedia.com/Colon-Hotels-Spa-Hotel.0-0-d601867-tSpaHotel.Travel-Guide-Filter-Hotels)

![Panoramic view of El Valle de Anton town surrounded by mountains in Panama](https://images.trvl-media.com/place/6053180/c16502d5-7d2c-4d59-91a1-745c940461bf.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### El Valle de Anton

[](https://expedia.com/El-Valle-De-Anton-Hotels-Spa-Hotel.0-0-d6053180-tSpaHotel.Travel-Guide-Filter-Hotels)

## Check availability on Panama Resorts & Hotels with Spas

Tonight

[Apr 2 - Apr 3](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-02&endDate=2026-04-03&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Apr 3 - Apr 4](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-03&endDate=2026-04-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-03&endDate=2026-04-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-10&endDate=2026-04-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Panama hotels with a spa

![Steam room, body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/9e776b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/86e96c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/ab95ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms, City View | View from room](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/d12ffdbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

[](https://www.expedia.com/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,003 reviews)

- Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.

$169 nightly

$186 total

Apr 4 - Apr 5

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/757e8465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/5f648ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Crowne Plaza Panama Airport by IHG

[](https://www.expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)

Tocumen

8.6/10

Excellent

(2,504 reviews)

$133 nightly

$146 total

Apr 28 - Apr 29

Total with taxes and fees

[](https://www.expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)

![Couples treatment rooms, steam room, Turkish bath, body treatments](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/0b681c03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c579d87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/db85bc00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

[](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information)

Juan Diaz

9.6/10

Exceptional

(682 reviews)

- Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape.

$245 nightly

$270 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information)

![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/7bb8f38a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marriott Panama Hotel

[](https://www.expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

Panama City

9.0/10

Wonderful

(1,006 reviews)

$152 nightly

$167 total

Apr 25 - Apr 26

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/80d0e2a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/86dd447e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bristol Panama, a Registry Collection Hotel

[](https://www.expedia.com/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information)

Bella Vista

9.4/10

Exceptional

(1,005 reviews)

- Immerse in luxurious tranquility at this Art Deco hotel with 6 treatment rooms and an outdoor pool for a rejuvenating retreat.

$194 nightly

$213 total

May 1 - May 2

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/79004c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Urban Suite,1 King, Partial City view | In-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/0b373179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/8f2104c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/1175365b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### W Panama

[](https://www.expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,000 reviews)

- Revitalize at this luxury hotel with three hot tubs, yoga classes, and rejuvenating massage services in a serene garden setting.

$269 nightly

$296 total

May 2 - May 3

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Couples treatment rooms, Turkish bath, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/e77a4c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/1a303895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/53f67005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Radisson Colon 2,000 Hotel & Casino

[](https://www.expedia.com/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information)

Barrio Sur

8.2/10

Very Good

(887 reviews)

- Rejuvenate at this waterfront hotel featuring couples spa treatments, an outdoor pool, and hot stone massages for a serene escape.

$109 nightly

$120 total

Apr 4 - Apr 5

Total with taxes and fees

[](https://www.expedia.com/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information)

![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/8d3d5a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/88416317.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, swim-up bar, poolside bar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/83d16a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ccd122a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sofitel Legend Casco Viejo, Panama City 

[](https://www.expedia.com/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information)

Casco Viejo

9.8/10

Exceptional

(628 reviews)

- Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.

$347 nightly

$381 total

Apr 27 - Apr 28

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information)

![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/f95b4a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (PAB 21 per person)](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/22409c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/58ea7ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sheraton Grand Panama

[](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

San Francisco

8.6/10

Excellent

(1,003 reviews)

- Immerse in tranquility at this Art Deco resort with two treatment rooms for couples and a Turkish bath, where expert spa therapists await.

$134 nightly

$148 total

May 1 - May 2

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/124fc0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/99beffbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/37502420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch served; American cuisine](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/eb1560c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Panama

[](https://www.expedia.com/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,003 reviews)

- Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.

$234 nightly

$257 total

May 1 - May 2

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Panama Hotel Reviews

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg)

### Hotel Riu Plaza Panama

10/10 Excellent

"Room was great, clean, friendly staff, and very convenient location."

[](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg)

### Waymore Hotel Spa & Casino

8/10 Good

"I didnt use the breakfast nor parking, but the casino was ok."

[](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information)

![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg)

### The Executive Hotel

8/10 Good

"Overall, our stay was fine for the one night we stayed. The hotel arranged transportation from & to the airport but were a little difficult to contact. We ended up calling them from the US to make the arrangements. The breakfast was good. It's a city location. The room set off my dust mite allergy from either the bedding, wall to wall carpet or drapes or all three."

[](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information)

![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg)

### Sheraton Grand Panama

10/10 Excellent

"Great breakfast great spa"

[](https://expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![Ramada Plaza by Wyndham Panama Punta Pacifica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b_y.jpg)

### Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent

"Clean and beautiful room. Comfortable beds. Breakfast was good. Wished there was another choice of protein besides pork, not everyone eats pork."

[](https://expedia.com/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information)

![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg)

### Courtyard by Marriott Panama Multiplaza Mall

6/10 Okay

"It’s very convenient for shopping "

[](https://expedia.com/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information)

![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg)

### Dreams Playa Bonita Panama - All Inclusive

6/10 Okay

"The Room Service was pretty much non-existent. They said they always had a 40-minute wait. I gave up on them for the trip. The restaurants were very limited, and the food was just ok. Some of the staff seemed like they needed more training. The resort is dated. The AC did work though and we never went hungry. The staff was nice."

[](https://expedia.com/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information)

![Hotel Riu Playa Blanca - All Inclusive](https://images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/737d5dbd_y.jpg)

### Hotel Riu Playa Blanca - All Inclusive

10/10 Excellent

"The staff was amazing, the food was great, and it was a very family friendly experience!!! Couldn't recommend higher!!!"

[](https://expedia.com/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information)

![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg)

### Principe Hotel and Suites

10/10 Excellent

"I really enjoyed my stay. I went there on the 24th of march and left today, which is the 31st of march 2026\. There restaurants where so near by and a food store next door the pool was good the rooms where very nice. The only thing was missing was having a microwave in the rooms other wise the rooms met my expectations. "

[](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information)

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