Resorts & Hotels with Spas in Panama from $128

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Top Cities in Panama

Check availability on Panama Resorts & Hotels with Spas

This weekend
Next weekend

Our top choices for Panama hotels with a spa

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,007 reviews)
  • cleanliness
    Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.
$159 nightly
The price is $175
May 9 - May 10
Total with taxes and fees
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
Tocumen
8.6 out of 10, Excellent, (2,510 reviews)
$128 nightly
The price is $141
May 30 - May 31
Total with taxes and fees
Crowne Plaza Panama Airport by IHG

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (690 reviews)
  • cleanliness
    Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape.
$247 nightly
The price is $271
May 15 - May 16
Total with taxes and fees
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1,001 reviews)
$161 nightly
The price is $177
May 9 - May 10
Total with taxes and fees
Marriott Panama Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Immerse in luxurious tranquility at this Art Deco hotel with 6 treatment rooms and an outdoor pool for a rejuvenating retreat.
$179 nightly
The price is $198
May 8 - May 9
Total with taxes and fees
Bristol Panama, a Registry Collection Hotel

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Revitalize at this luxury hotel with three hot tubs, yoga classes, and rejuvenating massage services in a serene garden setting.
$179 nightly
The price is $197
May 30 - May 31
Total with taxes and fees
W Panama

Radisson Colon 2,000 Hotel & Casino

Radisson Colon 2,000 Hotel & Casino
4.0 star property
Barrio Sur
8.2 out of 10, Very Good, (911 reviews)
  • cleanliness
    Rejuvenate at this waterfront hotel featuring couples spa treatments, an outdoor pool, and hot stone massages for a serene escape.
$116 nightly
The price is $128
May 16 - May 17
Total with taxes and fees
Radisson Colon 2,000 Hotel & Casino

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (645 reviews)
  • cleanliness
    Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.
$306 nightly
The price is $337
Jun 1 - Jun 2
Total with taxes and fees
Sofitel Legend Casco Viejo, Panama City

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,006 reviews)
  • cleanliness
    Immerse in tranquility at this Art Deco resort with two treatment rooms for couples and a Turkish bath, where expert spa therapists await.
$134 nightly
The price is $148
May 8 - May 9
Total with taxes and fees
Sheraton Grand Panama

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.
$237 nightly
The price is $261
May 31 - Jun 1
Total with taxes and fees
Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Panama Hotel Reviews