A tropical island with palm trees and a clear blue sky.

Resorts & Hotels with Spas in Panama from $128

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Top Cities in Panama

A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.
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Panama City

Panama City

Check availability on Panama Resorts & Hotels with Spas

This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Panama hotels with a spa

A modern reception area with a large window, a geometric patterned floor, and two potted plants.

1. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,001 reviews)
  • cleanliness
    Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.
$199 nightly
The price is $219
Sep 23 - Sep 24
Total with taxes and fees
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.

2. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
Tocumen Airport
8.6 out of 10, Excellent, (2,728 reviews)
$128 nightly
The price is $141
Oct 1 - Oct 2
Total with taxes and fees
Crowne Plaza Panama Airport by IHG
A spacious lobby with a reception desk, seating area, and decorative elements like a large painting and a plant.

3. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (752 reviews)
  • cleanliness
    Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape.
$269 nightly
The price is $296
Oct 15 - Oct 16
Total with taxes and fees
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern hotel lobby with a reception desk, seating area, and a hallway with decorative elements.

4. Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.2 out of 10, Wonderful, (1,003 reviews)
$178 nightly
The price is $196
Oct 10 - Oct 11
Total with taxes and fees
Marriott Panama Hotel
A hotel room with a large window offering a city view, a bed, a chair, and a small table with a tray.

5. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Immerse in luxurious tranquility at this Art Deco hotel with 6 treatment rooms and an outdoor pool for a rejuvenating retreat.
$199 nightly
The price is $220
Oct 9 - Oct 10
Total with taxes and fees
Bristol Panama, a Registry Collection Hotel
A modern lobby with a bar area, seating, and a colorful mural.

6. W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Revitalize at this luxury hotel with three hot tubs, yoga classes, and rejuvenating massage services in a serene garden setting.
$223 nightly
The price is $246
Oct 11 - Oct 12
Total with taxes and fees
W Panama
A room with a bed, a small table with candles, and a shelf with towels.

7. Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
4.0 star property
Barrio Sur
8.2 out of 10, Very good, (982 reviews)
  • cleanliness
    Rejuvenate at this waterfront hotel featuring couples spa treatments, an outdoor pool, and hot stone massages for a serene escape.
$116 nightly
The price is $128
Oct 5 - Oct 6
Total with taxes and fees
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
A hotel room with a checkered floor, a window with white curtains, and a lounge area with chairs and tables.

8. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (750 reviews)
  • cleanliness
    Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.
$356 nightly
The price is $391
Oct 6 - Oct 7
Total with taxes and fees
Sofitel Legend Casco Viejo, Panama City
A spa area with a hot tub, candles, and a curved bench.

9. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,003 reviews)
  • cleanliness
    Immerse in tranquility at this Art Deco resort with two treatment rooms for couples and a Turkish bath, where expert spa therapists await.
$176 nightly
The price is $193
Oct 1 - Oct 2
Total with taxes and fees
Sheraton Grand Panama
A reception desk with a logo, a patterned wall, and a potted plant.

10. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,005 reviews)
  • cleanliness
    Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.
$245 nightly
The price is $270
Oct 9 - Oct 10
Total with taxes and fees
Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

8/10 Good
"I have known this place when it was Veneto… Many years ago. They have done a great job renovating the hotel, casino and the all building! The ambiance and the spirit hasn’t come back. They had orchestras and bands, today they have karaoke."
Claude 1-night trip
Posted 3 hours ago
Waymore Hotel Spa & Casino

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