Title: Panama Resorts & Hotels with Spas from $120 - Fully Refundable Options - Expedia.com

[Panama Travel Guide](https://expedia.com/Panama.dx142)[Panama Hotels](https://expedia.com/Destinations-In-Panama.d142.Hotel-Destinations)[Vacation Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Vacation-Rental-Destinations)[Panama Flights](https://expedia.com/Destinations-In-Panama.d142.Flight-Destinations)[Car Rentals in Panama](https://expedia.com/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.com/Panama.d142.Destination-Travel-Guides)

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## Top Cities in Panama

![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Panama City

[](https://expedia.com/Panama-City-Hotels-Spa-Hotel.0-0-d2897-tSpaHotel.Travel-Guide-Filter-Hotels)

![ISLA COLON BOCAS DEL TORO](https://images.trvl-media.com/place/6023445/f17b18cc-4a72-405d-ab41-dfd48c15b97d.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Bocas del Toro

[](https://expedia.com/Bocas-Del-Toro-Hotels-Spa-Hotel.0-0-d6023445-tSpaHotel.Travel-Guide-Filter-Hotels)

![Idyllic Sunset at Playa Blanca, Panama](https://images.trvl-media.com/place/6246042/058a4e01-e481-4197-9791-26c53b4ee917.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Rio Hato

[](https://expedia.com/Rio-Hato-Hotels-Spa-Hotel.0-0-d6246042-tSpaHotel.Travel-Guide-Filter-Hotels)

![Sunrise with a view at Volcán Barú in Panama](https://images.trvl-media.com/place/500194/a9fdba1c-ad36-4683-90ac-2cdb584e103b.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Boquete

[](https://expedia.com/Boquete-Hotels-Spa-Hotel.0-0-d500194-tSpaHotel.Travel-Guide-Filter-Hotels)

![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Colon

[](https://expedia.com/Colon-Hotels-Spa-Hotel.0-0-d601867-tSpaHotel.Travel-Guide-Filter-Hotels)

![Panoramic view of El Valle de Anton town surrounded by mountains in Panama](https://images.trvl-media.com/place/6053180/c16502d5-7d2c-4d59-91a1-745c940461bf.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### El Valle de Anton

[](https://expedia.com/El-Valle-De-Anton-Hotels-Spa-Hotel.0-0-d6053180-tSpaHotel.Travel-Guide-Filter-Hotels)

## Check availability on Panama Resorts & Hotels with Spas

Tonight

[Apr 7 - Apr 8](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-07&endDate=2026-04-08&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Apr 8 - Apr 9](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-08&endDate=2026-04-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-10&endDate=2026-04-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=142&startDate=2026-04-17&endDate=2026-04-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Panama hotels with a spa

![Steam room, body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/9e776b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/86e96c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/ab95ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

[](https://www.expedia.com/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,004 reviews)

- Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.

$159 nightly

$175 total

May 9 - May 10

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/757e8465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/5f648ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Crowne Plaza Panama Airport by IHG

[](https://www.expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)

Tocumen

8.6/10

Excellent

(2,497 reviews)

$137 nightly

$151 total

Apr 28 - Apr 29

Total with taxes and fees

[](https://www.expedia.com/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information)

![Couples treatment rooms, steam room, Turkish bath, body treatments](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/0b681c03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ea9ff933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/db85bc00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

[](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information)

Juan Diaz

9.6/10

Exceptional

(685 reviews)

- Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape.

$269 nightly

$296 total

May 2 - May 3

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information)

![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/7bb8f38a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/860def94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marriott Panama Hotel

[](https://www.expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

Panama City

9.0/10

Wonderful

(1,005 reviews)

$161 nightly

$177 total

Apr 17 - Apr 18

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/80d0e2a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/86dd447e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8e0cdd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bristol Panama, a Registry Collection Hotel

[](https://www.expedia.com/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information)

Bella Vista

9.4/10

Exceptional

(1,011 reviews)

- Immerse in luxurious tranquility at this Art Deco hotel with 6 treatment rooms and an outdoor pool for a rejuvenating retreat.

$194 nightly

$213 total

May 7 - May 8

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/79004c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Urban Suite,1 King, Partial City view | In-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/0b373179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, local cuisine](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/1175365b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### W Panama

[](https://www.expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,006 reviews)

- Revitalize at this luxury hotel with three hot tubs, yoga classes, and rejuvenating massage services in a serene garden setting.

$223 nightly

$246 total

May 9 - May 10

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Couples treatment rooms, Turkish bath, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/1a303895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/665077af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/e77a4c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Radisson Colon 2,000 Hotel & Casino

[](https://www.expedia.com/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information)

Barrio Sur

8.2/10

Very Good

(892 reviews)

- Rejuvenate at this waterfront hotel featuring couples spa treatments, an outdoor pool, and hot stone massages for a serene escape.

$109 nightly

$120 total

Apr 9 - Apr 10

Total with taxes and fees

[](https://www.expedia.com/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information)

![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/8d3d5a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down comforters, pillowtop beds, minibar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/ccd122a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, swim-up bar, poolside bar](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/83d16a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/73000000/72990000/72981200/72981169/c28c4592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sofitel Legend Casco Viejo, Panama City 

[](https://www.expedia.com/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information)

Casco Viejo

9.8/10

Exceptional

(630 reviews)

- Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.

$347 nightly

$381 total

Apr 27 - Apr 28

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information)

![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/f95b4a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/c780324d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/22409c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/58ea7ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sheraton Grand Panama

[](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

San Francisco

8.6/10

Excellent

(1,001 reviews)

- Immerse in tranquility at this Art Deco resort with two treatment rooms for couples and a Turkish bath, where expert spa therapists await.

$127 nightly

$139 total

May 1 - May 2

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![Sports facility](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/124fc0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch served; American cuisine](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/eb1560c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch served; American cuisine](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/17d1dc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5940000/5938200/5938139/37502420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Panama

[](https://www.expedia.com/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information)

Bella Vista

8.8/10

Excellent

(1,002 reviews)

- Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.

$234 nightly

$257 total

May 1 - May 2

Total with taxes and fees

[](https://www.expedia.com/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information)

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## Top Panama Hotel Reviews

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg)

### Hotel Riu Plaza Panama

10/10 Excellent

"Most amazing breakfast ever"

[](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg)

### The Executive Hotel

10/10 Excellent

"The staff were very helpful and friendly. The rooms were always clean, especially the washroom area."

[](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information)

![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg)

### Sheraton Grand Panama

10/10 Excellent

"Excellent "

[](https://expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg)

### Principe Hotel and Suites

10/10 Excellent

"Exactly how it looks. No coffee"

[](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information)

![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg)

### Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent

"First of alll this hotel is under rated this is near 5 star , just a few minor touch up and get rid of the moist smell nd it’s perfect "

[](https://expedia.com/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information)

![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg)

### Waymore Hotel Spa & Casino

10/10 Excellent

"The property was good, but I could still smell mold on floor 7, and when you order the food at the pool, it reaches you cold"

[](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information)

![Hotel Riu Playa Blanca - All Inclusive](https://images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/60f3aac3_y.jpg)

### Hotel Riu Playa Blanca - All Inclusive

10/10 Excellent

"Great stay, the food excellent "

[](https://expedia.com/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information)

![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg)

### W Panama

10/10 Excellent

"Yes everything met my needs the only thing I didn’t like is that the beds are kinda stiff and I have even seen reviews online about the beds but other than that I enjoyed my time and can’t wait to be back hopefully in December."

[](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Hotel Ojos del Rio](https://images.trvl-media.com/lodging/11000000/10540000/10538500/10538417/dddd2643_y.jpg)

### Hotel Ojos del Rio

10/10 Excellent

"Todo perfecto, ubicación inmejorable, es mi hotel en Cuidad de Panamá"

[](https://expedia.com/Panama-City-Hotels-Hotel-Ojos-Del-Rio.h10538417.Hotel-Information)

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