Title: The Best 5 Star Hotels in Mount Pleasant  | Expedia.com

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## Check availability on Mount Pleasant 5 Star Hotels

Tonight

[Feb 26 - Feb 27](https://www.expedia.com/Hotel-Search?regionId=6084665&startDate=2026-02-26&endDate=2026-02-27&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 27 - Feb 28](https://www.expedia.com/Hotel-Search?regionId=6084665&startDate=2026-02-27&endDate=2026-02-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6084665&startDate=2026-02-27&endDate=2026-03-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6084665&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Top Mount Pleasant Hotel Reviews

## Find out more about Mount Pleasant

There's nothing wrong with enjoying the finer things in life. Add further luxury on your next trip to Mount Pleasant by treating yourself to the best of the best when it comes to accommodation. It's an ideal pairing. There's no reason to delay a getaway to Mount Pleasant any longer. You'll join the multitudes of vacationers who have made Mount Pleasant so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Book one of Expedia's luxurious 5-star hotels in Mount Pleasant and get ready to enjoy the getaway of a lifetime.

### 5-Star Hotels in Mount Pleasant

You'll have a fantastic time at one of these 5-star hotels. High-end restaurants, concierges, and pillow-fluffing are all at the ready. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What kind of amenities will make your stay a wonderful one? A deep-tissue massage to help your cares fall away? A concierge to help you suggest the next attraction to visit? Beautiful furniture, piping hot coffees, and even spectacular views...these hotels have it all. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. 

Yearning for experiences outside your hotel room? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Mount Pleasant are waiting for you to relax after a busy day.

### Make Your Escape

The results are in, and Mount Pleasant 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Don't put off your dream vacation any longer -- Expedia can help you land a great deal on accommodation. Decide on one of the 5-star hotels in Mount Pleasant today and settle down in the lap of luxury tomorrow.

## Explore a world of travel with Expedia

- Flights
- Cars

- [Flights from New York (JFK) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/jfk/mpn/new-york-to-mount-pleasant)
- [Flights from Santiago (SCL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/scl/mpn/santiago-to-mount-pleasant)
- [Flights from Dallas (DFW) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/dfw/mpn/dallas-to-mount-pleasant)
- [Flights from Punta Arenas (PUQ) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/puq/mpn/punta-arenas-to-mount-pleasant)
- [Flights from Los Angeles (LAX) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/lax/mpn/los-angeles-to-mount-pleasant)
- [Flights from London (LHR) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/lhr/mpn/london-to-mount-pleasant)
- [Flights from Tampa (TPA) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/tpa/mpn/tampa-to-mount-pleasant)
- [Flights from Buenos Aires (EZE) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/eze/mpn/buenos-aires-to-mount-pleasant)
- [Flights from Rio Gallegos (RGL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/rgl/mpn/rio-gallegos-to-mount-pleasant)
- [Flights from Mount Pleasant ](https://www.expedia.com/lp/airports/mpn/flights-from-mount-pleasant-airport)
- [Flights from Saginaw (MBS) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/mbs/mpn/saginaw-to-mount-pleasant)
- [Flights from San Francisco (SFO) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/sfo/mpn/san-francisco-to-mount-pleasant)
- [Flights from Brize Norton (BZZ) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/bzz/mpn/brize-norton-to-mount-pleasant)
- [Flights from Chicago (ORD) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/ord/mpn/chicago-to-mount-pleasant)
- [Flights from Denver (DEN) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/den/mpn/denver-to-mount-pleasant)
- [Flights from Seattle (SEA) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/sea/mpn/seattle-to-mount-pleasant)
- [Flights from São Paulo (GRU) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/gru/mpn/sao-paulo-to-mount-pleasant)
- [Flights from Minneapolis (MSP) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/msp/mpn/minneapolis-to-mount-pleasant)
- [Flights from Atlanta (ATL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/atl/mpn/atlanta-to-mount-pleasant)
- [Flights from Philadelphia (PHL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/phl/mpn/philadelphia-to-mount-pleasant)
- [Flights from Boston (BOS) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/bos/mpn/boston-to-mount-pleasant)
- [Flights from Houston (IAH) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/iah/mpn/houston-to-mount-pleasant)
- [Flights from Auckland (AKL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/akl/mpn/auckland-to-mount-pleasant)
- [Flights from Portland (PDX) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/pdx/mpn/portland-to-mount-pleasant)
- [Flights from Miami (MIA) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/mia/mpn/miami-to-mount-pleasant)
- [Flights from Raleigh (RDU) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/rdu/mpn/raleigh-to-mount-pleasant)
- [Flights from Baltimore (BWI) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/bwi/mpn/baltimore-to-mount-pleasant)
- [Flights from Lansing (LAN) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/lan/mpn/lansing-to-mount-pleasant)
- [Flights from Charleston (CHS) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/chs/mpn/charleston-to-mount-pleasant)
- [Flights from Kansas City (MCI) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/mci/mpn/kansas-city-to-mount-pleasant)
- [Flights from Orlando (MCO) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/mco/mpn/orlando-to-mount-pleasant)
- [Flights from Pittsburgh (PIT) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/pit/mpn/pittsburgh-to-mount-pleasant)
- [Flights from San Diego (SAN) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/san/mpn/san-diego-to-mount-pleasant)
- [Flights from Charlotte (CLT) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/clt/mpn/charlotte-to-mount-pleasant)
- [Flights from Salt Lake City (SLC) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/slc/mpn/salt-lake-city-to-mount-pleasant)
- [Flights from Johannesburg (JNB) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/jnb/mpn/johannesburg-to-mount-pleasant)
- [Flights from Ushuaia (USH) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/ush/mpn/ushuaia-to-mount-pleasant)
- [Flights from Montevideo (MVD) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/mvd/mpn/montevideo-to-mount-pleasant)
- [Flights from New Orleans (MSY) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/msy/mpn/new-orleans-to-mount-pleasant)
- [Flights from Washington (IAD) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/iad/mpn/washington-to-mount-pleasant)
- [Flights from New York (NYC) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/nyc/mpn/new-york-to-mount-pleasant)
- [Flights from New York (LGA) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/lga/mpn/new-york-to-mount-pleasant)
- [Flights from Detroit (DTW) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/dtw/mpn/detroit-to-mount-pleasant)
- [Flights from Dubai (DXB) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/dxb/mpn/dubai-to-mount-pleasant)
- [Flights from St. Louis (STL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/stl/mpn/st-louis-to-mount-pleasant)
- [Flights from Sydney (SYD) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/syd/mpn/sydney-to-mount-pleasant)
- [Flights from Zürich (ZRH) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/zrh/mpn/zurich-to-mount-pleasant)
- [Flights from Memphis (MEM) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/mem/mpn/memphis-to-mount-pleasant)
- [Flights from Sao Paulo (SAO) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/sao/mpn/sao-paulo-to-mount-pleasant)
- [Flights from Omaha (OMA) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/oma/mpn/omaha-to-mount-pleasant)
- [Flights from Asheville (AVL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/avl/mpn/asheville-to-mount-pleasant)
- [Flights from Las Vegas (LAS) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/las/mpn/las-vegas-to-mount-pleasant)
- [Flights from Little Rock (LIT) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/lit/mpn/little-rock-to-mount-pleasant)
- [Flights from Buenos Aires (AEP) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/aep/mpn/buenos-aires-to-mount-pleasant)
- [Flights from Phoenix (PHX) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/phx/mpn/phoenix-to-mount-pleasant)
- [Flights from Kuala Lumpur (KUL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/kul/mpn/kuala-lumpur-to-mount-pleasant)
- [Flights from Bogotá (BOG) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/bog/mpn/bogota-to-mount-pleasant)
- [Flights from Corpus Christi (CRP) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/crp/mpn/corpus-christi-to-mount-pleasant)
- [Flights from West Palm Beach (PBI) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/pbi/mpn/west-palm-beach-to-mount-pleasant)
- [Flights from San Antonio (SAT) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/sat/mpn/san-antonio-to-mount-pleasant)
- [Flights from Córdoba (COR) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/cor/mpn/cordoba-to-mount-pleasant)
- [Flights from Tel Aviv (TLV) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/tlv/mpn/tel-aviv-to-mount-pleasant)
- [Flights from Panama City (PTY) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/pty/mpn/panama-city-to-mount-pleasant)
- [Flights from Buenos Aires (BUE) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/bue/mpn/buenos-aires-to-mount-pleasant)
- [Flights from Fort Lauderdale (FLL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/fll/mpn/fort-lauderdale-to-mount-pleasant)
- [Flights from Oslo (OSL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/osl/mpn/oslo-to-mount-pleasant)
- [Flights from Nassau (NAS) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/nas/mpn/nassau-to-mount-pleasant)
- [Flights from Quito (UIO) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/uio/mpn/quito-to-mount-pleasant)
- [Flights from Lima (LIM) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/lim/mpn/lima-to-mount-pleasant)
- [Flights from Warsaw (WAW) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/waw/mpn/warsaw-to-mount-pleasant)
- [Flights from Austin (AUS) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/aus/mpn/austin-to-mount-pleasant)
- [Flights from Buffalo (BUF) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/buf/mpn/buffalo-to-mount-pleasant)
- [Flights from Doha (DOH) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/doh/mpn/doha-to-mount-pleasant)
- [Flights from Munich (MUC) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/muc/mpn/munich-to-mount-pleasant)
- [Flights from Nairobi (NBO) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/nbo/mpn/nairobi-to-mount-pleasant)
- [Flights from Frankfurt (FRA) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/fra/mpn/frankfurt-to-mount-pleasant)
- [Flights from Gold Coast (OOL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/ool/mpn/gold-coast-to-mount-pleasant)
- [Flights from Hancock (CMX) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/cmx/mpn/hancock-to-mount-pleasant)
- [Flights from Delhi (DEL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/del/mpn/delhi-to-mount-pleasant)
- [Flights from Latrobe (LBE) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/lbe/mpn/latrobe-to-mount-pleasant)
- [Flights from Addis Ababa (ADD) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/add/mpn/addis-ababa-to-mount-pleasant)
- [Flights from Mendoza (MDZ) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/mdz/mpn/mendoza-to-mount-pleasant)
- [Flights from Guatemala City (GUA) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/gua/mpn/guatemala-city-to-mount-pleasant)
- [Flights from Knoxville (TYS) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/tys/mpn/knoxville-to-mount-pleasant)
- [Flights from Yuma (YUM) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/yum/mpn/yuma-to-mount-pleasant)
- [Flights from Perth (PER) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/per/mpn/perth-to-mount-pleasant)
- [Flights from Vienna (VIE) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/vie/mpn/vienna-to-mount-pleasant)
- [Flights from Louisville (SDF) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/sdf/mpn/louisville-to-mount-pleasant)
- [Flights from Baton Rouge (BTR) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/btr/mpn/baton-rouge-to-mount-pleasant)
- [Flights from Macon (MCN) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/mcn/mpn/macon-to-mount-pleasant)
- [Flights from Lafayette (LFT) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/lft/mpn/lafayette-to-mount-pleasant)
- [Flights from Indianapolis (IND) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/ind/mpn/indianapolis-to-mount-pleasant)
- [Flights from Peoria (PIA) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/pia/mpn/peoria-to-mount-pleasant)
- [Flights from Orange County (SNA) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/sna/mpn/orange-county-to-mount-pleasant)
- [Flights from Montreal (YUL) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/yul/mpn/montreal-to-mount-pleasant)
- [Flights from Paris (CDG) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/cdg/mpn/paris-to-mount-pleasant)
- [Flights from Birmingham (BHX) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/bhx/mpn/birmingham-to-mount-pleasant)
- [Flights from Edinburgh (EDI) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/edi/mpn/edinburgh-to-mount-pleasant)
- [Flights from Accra (ACC) to Mount Pleasant (MPN) ](https://www.expedia.com/lp/flights/acc/mpn/accra-to-mount-pleasant)

- [Car rental Mount Pleasant Airport (MPN) ](https://www.expedia.com/Car-Rentals-In-Mount-Pleasant.d6024687.Car-Rental-Guide)