Butterknife Vacations from $314

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Your Butterknife Vacation

Take the fuss out of organizing your next break with a Butterknife vacation package. Immerse yourself in the sights and sounds of this enticing neighborhood and experience what it has to offer. Not sure where to go during your trip to Butterknife? Nearby attractions like Periwinkle Way, Sanibel Island Golf Club and Dunes Golf and Tennis Club are good places to start. Expedia is here to put your plans into action. Book your ideal Butterknife vacation now.

The Latest Butterknife Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina

3 out of 5
Price was $739, price is now $314 per person
$314
per person
Feb 5 - Feb 8
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
9.2/10 Wonderful! (1,001 reviews)
Very nice Staff is excellent.

Reviewed on Nov 24, 2025

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
Villas
Save 100% on your flight
Price was $620, price is now $316 per person
$316
per person
Feb 5 - Feb 8
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
8.6/10 Excellent! (1,002 reviews)
the place was nice but there was a cockroack in the bathroom.

Reviewed on Nov 20, 2025

The Perry Hotel Naples

The Perry Hotel Naples

4.5 out of 5
Save 100% on your flight
Price was $1,169, price is now $602 per person
$602
per person
Feb 5 - Feb 8
found 1 day ago
Roundtrip flight included
Boston (BOS) to Fort Myers (RSW)
9.6/10 Exceptional! (477 reviews)
The bed was very comfortable. The shower was clean and updated. We enjoyed the fire pits at night.

Reviewed on Nov 27, 2025

Innovation Hotel

Innovation Hotel

4 out of 5
Save 100% on your flight
Price was $1,985, price is now $1,106 per person
$1,106
per person
Feb 16 - Feb 21
found 21 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Fort Myers (RSW)
9.8/10 Exceptional! (527 reviews)
El personal súper amable y todo muy limpio,la habitación excelente

Reviewed on Nov 24, 2025

LaPlaya Beach & Golf Resort - A Noble House Resort

LaPlaya Beach & Golf Resort - A Noble House Resort

4.5 out of 5
Vanderbilt Beach
Save 100% on your flight
Price was $2,125, price is now $1,229 per person
$1,229
per person
Jan 9 - Jan 13
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Fort Myers (RSW)
9/10 Wonderful! (1,000 reviews)
Excellent Location and beach view. Excellent Restaurant. Room Toilet Plumbing issues continued although staff responded to the room quickly. Never seen a problem continuing to persist for our whole trip. Five separate times.

Reviewed on Nov 22, 2025

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Where to stay in Butterknife

Find the best Butterknife areas and neighborhoods for the activities you enjoy most. Learn more about Butterknife
Fort Myers featuring a sandy beach

West End

3 out of top 10 points of interest in this area

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

Find hotels in West End

Butterknife Hotel Deals

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
$204 nightly
The price is $228 total per night from Dec 17 to Dec 18
$228 total
Dec 17 - Dec 18
Total with taxes and fees
8.8/10 Excellent! (1,655 reviews)
This is a wonderful hotel, rooms are beautiful and amenities wonderful. We will definitely come back.

Reviewed on Nov 23, 2025

Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $181 total per night from Nov 30 to Dec 1
$181 total
Nov 30 - Dec 1
Total with taxes and fees
8.8/10 Excellent! (1,038 reviews)
Everything was perfect.

Reviewed on Nov 28, 2025

Lani Kai Beachfront Resort
Courtyard by Marriott Fort Myers Cape Coral

Courtyard by Marriott Fort Myers Cape Coral

3 out of 5
4455 Metro Pkwy Fort Myers FL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Dec 7 to Dec 8
$94 total
Dec 7 - Dec 8
Total with taxes and fees
8/10 Very Good! (1,007 reviews)
Nice front staff

Reviewed on Nov 21, 2025

Courtyard by Marriott Fort Myers Cape Coral
See all 14,665 properties in Butterknife
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Butterknife

Sanibel Island Southern Beach

Sanibel Island Southern Beach

4.5/5(171 reviews)

Why not spend a lazy afternoon at Sanibel Island Southern Beach during your trip to Sanibel?

Sanibel Island Southern Beach
Bowman\'s Beach which includes general coastal views and a sandy beach

Bowman's Beach

4.5/5(481 reviews)

Relax and revel in a visit to one of the area’s most beautiful beaches, great for swimming, fishing and finding special seashells.

Bowman's Beach
Sanibel Island Lighthouse which includes a beach, general coastal views and a sunset

Sanibel Island Lighthouse

4.5/5(1,092 reviews)

Although nobody knows how many shipwrecks it’s prevented, this lighthouse has been a welcome beacon for over a century. Visit it on an island that’s noted for shell collecting.

Sanibel Island Lighthouse

Things to do

Fort Myers Beach Sunset Excursion

Fort Myers Beach Sunset Excursion

$65
per adult
100% of travellers recommend
Fort Myers Beach Sunset Excursion
Southwest Florida Sunset Sail

Southwest Florida Sunset Sail

$70
per adult
100% of travellers recommend
Southwest Florida Sunset Sail
Dolphin and Sightseeing Tiki Cruise

Fort Myers Beach Dolphin & Sightseeing Tour Refreshments Included

$65
per adult
Fort Myers Beach Dolphin & Sightseeing Tour Refreshments Included
See all activities in Sanibel
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.