Cherokee Vacations from $460

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Your Cherokee Vacation

Our vacation packages to Cherokee allow you to create your own adventure. Tailor your journey to suit your interests and needs and make the most of your time in this exciting city. If taking in sights is on the to-do list during your trip to Cherokee, stop by major attractions like East Tennessee State University, Freedom Hall Civic Center and Johnson City Mall. No matter your travel plans or budget, organizing your ultimate tailored Cherokee vacation is a piece of cake with Expedia.

The Latest Cherokee vacation packages

Price found within the past 48 hours. Click for updated prices.
Americourt Hotel

Americourt Hotel

2.5 out of 5
Price was $540, price is now $460 per person
$460
per person
Sep 18 - Sep 20
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Tri-Cities (TRI)
6.6/10 (541 reviews)
Very welcoming to pets. And yes, the parking may be feel safe.

Reviewed on Mar 23, 2026

Motel 6 Kingsport, TN

Motel 6 Kingsport, TN

2 out of 5
Price was $783, price is now $668 per person
$668
per person
Sep 18 - Sep 20
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Tri-Cities (TRI)
8.2/10 Very Good! (1,005 reviews)
The motel was pleasant. The room was clean but very small to have a king sized bed. Staff was very friendly.

Reviewed on Jun 14, 2026

Travel Inn Bristol near State St

Travel Inn Bristol near State St

2.5 out of 5
Price was $958, price is now $828 per person
$828
per person
Sep 18 - Sep 20
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Tri-Cities (TRI)
5/10 (144 reviews)
AC worked well. Staff was helpful. Room was so,so.

Reviewed on Jun 4, 2026

Econo Lodge Kingsport East

Econo Lodge Kingsport East

2 out of 5
Price was $767, price is now $676 per person
$676
per person
Sep 18 - Sep 20
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Tri-Cities (TRI)
7.6/10 Good! (538 reviews)
The room was clean and the staff was very friendly.

Reviewed on Jun 13, 2026

Days Inn & Suites by Wyndham Johnson City

Days Inn & Suites by Wyndham Johnson City

3 out of 5
Price was $669, price is now $595 per person
$595
per person
Sep 18 - Sep 20
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Tri-Cities (TRI)
6/10 (1,004 reviews)
As described. Friendly and helpful staff!

Reviewed on Jun 22, 2026

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Discover the most popular places to visit in Cherokee

Bull Elk in Great Smokey Mountain National Park.

Winged Deer Park

4.5/5(19 reviews)

Explore the great outdoors at Winged Deer Park, a lovely green space in Johnson City. While you're here, you can savor the top-notch restaurants.

Winged Deer Park
Bones and remains of ancient animals in the museum on a glass shelf

Gray Fossil Museum

4/5(14 reviews)

You can spend time studying the exhibits at Gray Fossil Museum in Johnson City. Check out the top-notch restaurants or lively bars in this romantic area.

Gray Fossil Museum

East Tennessee State University

4.5/5(128 reviews)

Take a campus tour or just explore the area of East Tennessee State University, during your travels in Johnson City. While you're here, you can savor the top-notch restaurants.

East Tennessee State University

Cherokee Hotel Deals

Carnegie Hotel & Spa

Carnegie Hotel & Spa

4 out of 5
1216 W State Of Franklin Rd Johnson City TN
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $185 total per night from Jul 5 to Jul 6
$185 total
Jul 5 - Jul 6
Total with taxes and fees
9.8/10 Exceptional! (1,415 reviews)
"The Carnegie is a beautiful hotel with a vintage atmosphere. Rooms are spacious and clean. It's located near shopping and restaurants. We always stay at the Carnegie when we are in town."

Reviewed on Jun 20, 2026

Carnegie Hotel & Spa
Sleep Inn & Suites Johnson City

Sleep Inn & Suites Johnson City

2.5 out of 5
2020 Franklin Terrace Court Johnson City TN
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $94 total per night from Jul 13 to Jul 14
$94 total
Jul 13 - Jul 14
Total with taxes and fees
8.4/10 Very Good! (958 reviews)
"Room was clean. We have stayed at Sleep Inn several times over the years ands have always been happy with our stay."

Reviewed on Jun 22, 2026

Sleep Inn & Suites Johnson City
Echo Suites Extended Stay By Wyndham Johnson City Medical Cr

Echo Suites Extended Stay By Wyndham Johnson City Medical Cr

2 out of 5
1100 Clinchfield Street Johnson City TN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $93 total per night from Jun 28 to Jun 29
$93 total
Jun 28 - Jun 29
Total with taxes and fees
8.8/10 Excellent! (331 reviews)
"The bad: My bed frame sounded like I stepped on a cat anytime I moved. Refrigerator was louder than the TV. I did not get a good night sleep here. The good: clean, very clean. Close to the VA Hospital."

Reviewed on Jun 23, 2026

Echo Suites Extended Stay By Wyndham Johnson City Medical Cr
See all 533 properties in Cherokee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Cherokee Vacation Packages

Cherokee Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Tri-Cities Regional Airport (TRI)
Top Sights
Gray Fossil Museum, Johnson City Family Skatecenter and Wallabies

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Frequently asked questions

How much does a Cherokee vacation package cost?
You'll find cheap prices from $460 on Expedia for your Cherokee escape. However, factors like the length of stay, hotel choice and season will influence how much your vacation to Cherokee costs.
What are the cheapest months to go to Cherokee?
January, September and December are great times to search for cheap Cherokee vacation packages. Opting to travel in less busy periods means you can generally find better prices on hotels and flights.
How many days is enough for Cherokee?
Generally, a handful of days is enough to visit the top sights during your Cherokee vacation. However, if you want to have time to relax or go on day trips, think about extending your trip.
How to find the best Cherokee package deals?
Start your search for a Cherokee package deal by entering your travel dates and destination under our "Packages" tab. Then apply a few filters, like "Property type" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the ideal Cherokee package deal right away, simply play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Cherokee getaway off to a flying start.
Is it cheaper to book a Cherokee vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your car rental, flight and hotel into one great-value price and you could save hundreds of dollars. You'll usually snag a better deal than booking each component individually. And you'll still enjoy the flexibility to create a customized Cherokee vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Cherokee?
If you're considering a spur-of-the-moment Cherokee trip, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score amazing deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Cherokee vacation packages?
Set off on your dream trip to Cherokee with Expedia's Book Now, Pay Later vacations. There's no need to save like crazy or hold off until your next paycheck — we've teamed up with online lender Affirm to offer you financial flexibility. Our vacation packages with payment plans mean you can spread the total cost over 3, 6 or 12 months. With no hidden charges or late payment fees, it's easy to budget for your trip and snap up travel deals before they disappear.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.