Chillicothe Vacations from $281

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Your Chillicothe Vacation

With a vacation package to Chillicothe, say goodbye to endless planning and hello to an effortless adventure. Every detail of your escape has been taken care of before you go, so you can enjoy each moment discovering this interesting city. A trip to Chillicothe wouldn't be complete without seeing some major attractions, like Cedar Creek Golf Course. Check out Expedia's wide range of travel options and start planning your perfect vacation to Chillicothe now.

The Latest Chillicothe vacation packages

Price found within the past 48 hours. Click for updated prices.
My Place Hotel - Ankeny/ Des Moines, IA

My Place Hotel - Ankeny/ Des Moines, IA

3 out of 5
Price was $343, price is now $281 per person
$281
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
9/10 Wonderful! (758 reviews)
The rooms are clean, quiet and dog friendly. Everything we need for an overnight stay on our way through town.

Reviewed on Dec 31, 2025

Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
Downtown Des Moines
Price was $395, price is now $316 per person
$316
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
8/10 Very Good! (1,001 reviews)
Hotel was good option for walking to Casey Center for Paul McCartney concert. Lobby was filled with concert goers end of evening, and it took hotel over 30 minutes to open stairwell. People were piled up in lobby, security was nowhere to be found, and front desk didn't have keys to open stairwell. People were tired, had to use bathroom, etc, and it took too long to accommodate the guests needs.

Reviewed on Nov 16, 2025

Wildwood Lodge

Wildwood Lodge

3 out of 5
Price was $384, price is now $309 per person
$309
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
9.6/10 Exceptional! (1,194 reviews)
This place is gorgeous. Rustic lodge look. Beautiful fireplaces inside and out. Rooms were spacious and nice. The only reason I didn’t give five stars is our toilet kept running and you had to fiddle with the tank each time. But staff were very responsive when we first said something. Other than that, I was impressed! I will definitely stay here again!

Reviewed on Jan 15, 2026

Hilton Des Moines Downtown

Hilton Des Moines Downtown

3.5 out of 5
Downtown Des Moines
Price was $646, price is now $521 per person
$521
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
9/10 Wonderful! (1,000 reviews)
It was quick and easy to get airport transportation!

Reviewed on Jan 18, 2026

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
Downtown Des Moines
Price was $399, price is now $330 per person
$330
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
9.6/10 Exceptional! (1,037 reviews)
The staff was amazing--I had booked for the wrong week and showed up. I did a chat with Expedia and they got on the phone with the staff at the hotel. There was room at the inn--so they switched the booking for me for no extra charge. I was thrilled! the staff of the hotel greeted us each day, brought up a remote for the tv when we couldn't find it, lent us an umbrella (a nice bubble one too)--we couldn't have asked for anything more! The bathroom shower was amazing too.

Reviewed on Jan 20, 2026

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Chillicothe Hotel Deals

EverSpring Inn & Suites

EverSpring Inn & Suites

2.5 out of 5
2401 A Ave West Oskaloosa IA
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $111 total per night from Jan 23 to Jan 24
$111 total
Jan 23 - Jan 24
Total with taxes and fees
8/10 Very Good! (664 reviews)
I didnt have any breakfast and disnt venture into the food area. Parking wa more than satisfactory. Sink in the bathroom eas clogged and filled with water at every use.

Reviewed on Jan 13, 2026

EverSpring Inn & Suites
Cobblestone Hotel & Suites - Ottumwa

Cobblestone Hotel & Suites - Ottumwa

2.5 out of 5
108 Church St Ottumwa IA
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $108 total per night from Jan 24 to Jan 25
$108 total
Jan 24 - Jan 25
Total with taxes and fees
9.2/10 Wonderful! (249 reviews)
Always a great stay!

Reviewed on Jan 13, 2026

Cobblestone Hotel & Suites - Ottumwa
Fairfield Inn & Suites by Marriott Oskaloosa

Fairfield Inn & Suites by Marriott Oskaloosa

2.5 out of 5
2325 COAL MINE LOOP Oskaloosa IA
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $161 total per night from Jan 25 to Jan 26
$161 total
Jan 25 - Jan 26
Total with taxes and fees
9.2/10 Wonderful! (231 reviews)
Always clean and comfortable. Good complimentary breakfast options.

Reviewed on Jan 15, 2026

Fairfield Inn & Suites by Marriott Oskaloosa
See all 37 properties in Chillicothe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Chillicothe Vacation Packages

Chillicothe Essential Information

Language
English
Currency
U.S dollars
Top Sights
Wapello County Historical Museum, Airpower Museum and Memorial Park

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Frequently asked questions

How much does a Chillicothe vacation package cost?
You'll find cheap prices from $281 on Expedia for your Chillicothe getaway. However, factors like the season, length of stay and your choice of hotel will determine how much your vacation to Chillicothe costs.
What are the cheapest months to go to Chillicothe?
You're likely to find reduced prices and greater availability in February, July and December. Take a look at our cheap Chillicothe vacation packages and you could score some great off-season deals.
How many days is enough for Chillicothe?
The ideal duration of your Chillicothe vacation depends on what you'd like to see. Usually, a few days to a week will give you plenty of time to go to all the top attractions and explore some hidden spots along the way.
How to find the best Chillicothe package deals?
Use Expedia's filters to find some of the best Chillicothe package deals. When you start your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or look for Chillicothe package deals in the off-peak season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to book your vacation package as early as possible.
Is it cheaper to book a Chillicothe vacation as a package?
You can enjoy significant savings on your Chillicothe retreat by booking a tailored vacation package. Click on the "Package" heading, then select your destination and travel dates to see some great airfares and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Chillicothe?
Score incredible bargains by reserving your flights early with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for an impromptu Chillicothe break.
Does Expedia offer Book Now, Pay Later Chillicothe vacation packages?
Secure your ideal getaway to Chillicothe with help from our Book Now, Pay Later vacations. No need to save up or hold off until the next payday — we've joined forces with online lender Affirm to give you more flexibility and choice. Our vacation packages with payment plans mean you can spread the cost across 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stay on budget and snap up travel deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.