Clio Vacations from $366

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The Latest Clio vacation packages

Price found within the past 48 hours. Click for updated prices.
Florence Inn and Suites

Florence Inn and Suites

2.5 out of 5
Price was $408, price is now $366 per person
$366
per person
Jan 16 - Jan 19
found 22 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Florence (FLO)
6.4/10 (323 reviews)
The staff was very nice and helpful.

Reviewed on Nov 20, 2025

Quality Inn & Suites Lake City

Quality Inn & Suites Lake City

2.5 out of 5
Price was $539, price is now $473 per person
$473
per person
Jan 16 - Jan 19
found 22 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Florence (FLO)
7.2/10 Good! (164 reviews)
Number 1 it was overpriced, the room wash all that the first one was half cleaned...they moved me to another ...breakfast...the cereal area wasnt clean enough for me and they had a gallon of milk which is unsanitary to me...for breakfast u only get cereal or a plain ass waffle

Reviewed on Oct 23, 2025

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
Price was $516, price is now $458 per person
$458
per person
Jan 16 - Jan 19
found 22 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Florence (FLO)
9.2/10 Wonderful! (1,145 reviews)
Easy check in. Room was very clean. Easy on site parking.

Reviewed on Dec 10, 2025

Quality Inn Mullins - Marion

Quality Inn Mullins - Marion

2.5 out of 5
Price was $482, price is now $431 per person
$431
per person
Jan 16 - Jan 19
found 22 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Florence (FLO)
7.6/10 Good! (369 reviews)
It was ok clean would stay there again.

Reviewed on Dec 3, 2025

The Mantissa Hotel

The Mantissa Hotel

3 out of 5
Price was $640, price is now $573 per person
$573
per person
Jan 16 - Jan 19
found 22 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Florence (FLO)
9.2/10 Wonderful! (268 reviews)
Excellent and accommodating staff. Great and spacious room. We would definitely return.

Reviewed on Nov 23, 2025

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Clio Hotel Deals

Red Roof Inn Dillon, SC

Red Roof Inn Dillon, SC

2 out of 5
810 Radford Boulevard Dillon SC
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $62 total per night from Dec 14 to Dec 15
$62 total
Dec 14 - Dec 15
Total with taxes and fees
6.2/10 (969 reviews)
Very nice 👍

Reviewed on Dec 2, 2025

Red Roof Inn Dillon, SC
Days Inn by Wyndham Dillon

Days Inn by Wyndham Dillon

2 out of 5
823 Radford Blvd Dillon SC
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $67 total per night from Dec 14 to Dec 15
$67 total
Dec 14 - Dec 15
Total with taxes and fees
5.4/10 (868 reviews)
Really enjoyed my stay

Reviewed on Dec 6, 2025

Days Inn by Wyndham Dillon
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
817 Radford Blvd Dillon SC
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $87 total per night from Jan 11 to Jan 12
$87 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
7.2/10 Good! (757 reviews)
Staff was courteous and the room was clean.

Reviewed on Nov 11, 2025

Quality Inn & Suites
See all 52 properties in Clio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Clio Vacation Packages

Clio Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Florence Regional Airport (FLO)
Population
690

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Frequently asked questions

How much does a Clio vacation package cost?
You can pick up a vacation package to this popular destination from $366 on Expedia. But how much your vacation to Clio costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Clio?
You can generally find lower prices and better availability in January, June and October. Take a look at our cheap Clio vacation packages and you could get some great off-season deals.
How many days is enough for Clio?
With a well-organized schedule, you can easily visit the top Clio sights in a few days. But if you want to discover hidden gems or go on day trips, think about booking your Clio vacation for longer.
How to find the best Clio package deals?
Use Expedia's filters to help you find some great Clio package deals. When you begin your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or look for Clio package deals in the off-season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package as soon as possible.
Is it cheaper to book a Clio vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your car rental, hotel and flight into one great-value price and enjoy significant savings. You'll generally get a better deal than booking each component separately. And you'll still get the freedom to create a customized Clio vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Clio?
If you're considering a spur-of-the-moment Clio adventure, check out our last-minute deals that can be booked up to a week before you go. Prefer not to wait until the last minute? You can find sensational deals on your flights and hotels by booking ahead.
Does Expedia offer Book Now, Pay Later Clio vacation packages?
Your Clio break should be a relaxing escape from your daily routine, not a source of money worries. So to allow you extra flexibility, we've teamed up with online lender Affirm to offer our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.