Clio Vacations from $559

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The Latest Clio vacation packages

Price found within the past 48 hours. Click for updated prices.
The Inn at the Crossroads

The Inn at the Crossroads

2 out of 5
Price was $627, price is now $559 per person
$559
per person
Jun 27 - Jul 1
found 4 hours ago
Roundtrip flight included
New York (NYC) to Florence (FLO)
9.4/10 Exceptional! (868 reviews)
Could have a better breakfast. Everything was nice and clean

Reviewed on Apr 10, 2026

The Mantissa Hotel

The Mantissa Hotel

3 out of 5
Price was $1,094, price is now $991 per person
$991
per person
Jun 18 - Jun 22
found 1 day ago
Roundtrip non-stop flight included
Jackson (JAN) to Florence (FLO)
9.2/10 Wonderful! (280 reviews)
This hotel was truly a gem. I was so surprised to see the size of the room and the suite amenities . The linens and bedding were super nice and clean. The living space was large and had the feeling of being at home. A cute Boutique surprise when I walked into the room. Highly recommend!!

Reviewed on Apr 10, 2026

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 out of 5
Price was $1,017, price is now $924 per person
$924
per person
Jun 18 - Jun 22
found 1 day ago
Roundtrip non-stop flight included
Jackson (JAN) to Florence (FLO)
9.2/10 Wonderful! (1,004 reviews)
Loved it … breakfast options great as well

Reviewed on Mar 29, 2026

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

2.5 out of 5
Price was $1,011, price is now $920 per person
$920
per person
Jun 18 - Jun 22
found 1 day ago
Roundtrip non-stop flight included
Jackson (JAN) to Florence (FLO)
8.6/10 Excellent! (1,001 reviews)
The hotel was in a convenient location, right off of I-95, and had ample, safe parking. The staff was nice and helpful. The breakfast was good on the day we stayed. It included cheese omelette, a variety of breads, muffins, cinnamon roll, cereals, yogurts, hard boiled eggs, biscuits & mushroom gravy. The coffee was excellent, they have a machine that grinds beans every time it brews a cup of coffee. My only issue is that breakfast was until 9:30a.m. and by 9:15 there was only one cheese omelette left and the staff said no more items will be made, so several people were upset that the main breakfast offering was gone with 15 min left for breakfast. They should work to fix that problem because many folks like me pick hotels based on breakfast offerings and it is dissapointing to not have options with time left on the clock.

Reviewed on Apr 1, 2026

Springhill Suites by Marriott Cheraw

Springhill Suites by Marriott Cheraw

3 out of 5
Price was $1,028, price is now $937 per person
$937
per person
Jun 18 - Jun 22
found 1 day ago
Roundtrip non-stop flight included
Jackson (JAN) to Florence (FLO)
9.4/10 Exceptional! (309 reviews)
Front desk staff was wonderful. Room was very nice.

Reviewed on Mar 20, 2026

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Clio Hotel Deals

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

2.5 out of 5
2101 Florence Harllee Blvd Florence SC
Fully refundable
$130 nightly
The price is $146 total per night from May 3 to May 4
$146 total
May 3 - May 4
Total with taxes and fees
8.6/10 Excellent! (1,002 reviews)
One night stay

Reviewed on Apr 11, 2026

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Red Roof Inn Dillon, SC

Red Roof Inn Dillon, SC

2 out of 5
810 Radford Boulevard Dillon SC
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $65 total per night from Apr 14 to Apr 15
$65 total
Apr 14 - Apr 15
Total with taxes and fees
6.4/10 (1,006 reviews)
Yes

Reviewed on Apr 11, 2026

Red Roof Inn Dillon, SC
Best Western Executive Inn

Best Western Executive Inn

2.5 out of 5
1534 Highway 38 W Latta SC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $116 total per night from Apr 19 to Apr 20
$116 total
Apr 19 - Apr 20
Total with taxes and fees
8.2/10 Very Good! (981 reviews)
Carpet dirty every floor, the breakfast not up to par. No staff, front desk nice. Last 2 visit under renovations, really. Wouldn’t stay there again!

Reviewed on Apr 12, 2026

Best Western Executive Inn
See all 56 properties in Clio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Clio Vacation Packages

Clio Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Florence Regional Airport (FLO)
Population
690

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Frequently asked questions

How much does a Clio vacation package cost?
You can pick up a vacation package to this popular destination from $559 on Expedia. But how much your vacation to Clio costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Clio?
You can generally find lower prices and better availability in January, June and October. Take a look at our cheap Clio vacation packages and you could get some great off-season deals.
How many days is enough for Clio?
With a well-organized schedule, you can easily visit the top Clio sights in a few days. But if you want to discover hidden gems or go on day trips, think about booking your Clio vacation for longer.
How to find the best Clio package deals?
Use Expedia's filters to help you find some great Clio package deals. When you begin your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or look for Clio package deals in the off-season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package as soon as possible.
Is it cheaper to book a Clio vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your car rental, hotel and flight into one great-value price and enjoy significant savings. You'll generally get a better deal than booking each component separately. And you'll still get the freedom to create a customized Clio vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Clio?
If you're considering a spur-of-the-moment Clio adventure, check out our last-minute deals that can be booked up to a week before you go. Prefer not to wait until the last minute? You can find sensational deals on your flights and hotels by booking ahead.
Does Expedia offer Book Now, Pay Later Clio vacation packages?
Your Clio break should be a relaxing escape from your daily routine, not a source of money worries. So to allow you extra flexibility, we've teamed up with online lender Affirm to offer our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.