Desoto Acres Vacations from $538

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Your Desoto Acres Vacation

Immerse yourself in all this neighborhood has to offer with a tailor-made Desoto Acres vacation package. However you see yourself spending your days here, you'll find endless opportunities for adventure, relaxation and fun. Your trip to Desoto Acres wouldn't be complete without a stop at popular attractions nearby such as Sarasota Jungle Gardens, University of South Florida Sarasota and John and Mable Ringling Museum of Art. Don't just wish for it — take action! Lock in your ideal Desoto Acres vacation with Expedia and enjoy traveling your way.

The Latest Desoto Acres Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Lemon Bay Motel

Lemon Bay Motel

2 out of 5
Price was $1,046, price is now $538 per person
$538
per person
Dec 7 - Dec 12
found 9 hours ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Sarasota (SRQ)
8.6/10 Excellent! (28 reviews)
A little down the way

Reviewed on Oct 5, 2025

Cedar Cove Resort and Cottages

Cedar Cove Resort and Cottages

3 out of 5
Price was $1,797, price is now $925 per person
$925
per person
Nov 12 - Nov 19
found 1 day ago
Roundtrip flight included
Boston (BOS) to Sarasota (SRQ)
9.2/10 Wonderful! (463 reviews)
Beautiful experience steps from the beach perfect weekend getaway

Reviewed on Oct 8, 2025

Ocean Club Treasure Island Hotel

Ocean Club Treasure Island Hotel

4 out of 5
Sunshine Beach
Save 100% on your flight
Price was $1,737, price is now $972 per person
$972
per person
Dec 22 - Dec 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Tampa (TPA)
9.6/10 Exceptional! (635 reviews)
The place is great, excellent location, close to many outdoor activities, amazing ocean view, staff is very good and attentive to our needs, hotel is clean, parking very convenient, rooms are very nice, clean and confortable. We’ll definitely come back and recommend Ocean Club.

Reviewed on Oct 13, 2025

voco Sarasota by IHG

voco Sarasota by IHG

3.5 out of 5
Central Sarasota
Save 100% on your flight
Price was $1,316, price is now $767 per person
$767
per person
Dec 22 - Dec 29
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Tampa (TPA)
9.2/10 Wonderful! (1,003 reviews)
It was nice to have a gym available and it was always empty. Shower was my favorite park, really big and open, bed was super comfy. The elevators were outnof order though and the coffee machine in the room didnt work, but over all it was a pretty nice hotel. One of the nicest ive been too.

Reviewed on Oct 4, 2025

Bali Hai Beachfront Resort and Spa

Bali Hai Beachfront Resort and Spa

3.5 out of 5
Save 100% on your flight
Price was $1,544, price is now $918 per person
$918
per person
Nov 12 - Nov 19
found 1 day ago
Roundtrip flight included
Boston (BOS) to Sarasota (SRQ)
8.6/10 Excellent! (606 reviews)
Super access to beautiful beach. Nice amenities on property...pool, casual restaurant/bar, spa.

Reviewed on Oct 8, 2025

Where to stay in Desoto Acres

Find the best Desoto Acres areas and neighborhoods for the activities you enjoy most. Learn more about Desoto Acres
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South Sarasota

While visiting South Sarasota, you might make a stop by sights like The Landings and Coconuts Family Entertainment Center.

Find hotels in South Sarasota

Desoto Acres Hotel Deals

Kompose Boutique Hotel

Kompose Boutique Hotel

3 out of 5
965 University Pkwy, Sarasota, FL
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Oct 16 to Oct 17
$81 total
Oct 16 - Oct 17
Total with taxes and fees
9/10 Wonderful! (4,440 reviews)
"Beautiful hotel especially for the price."

Reviewed on Oct 9, 2025

Kompose Boutique Hotel
Tropical Beach Resorts

Tropical Beach Resorts

3.5 out of 5
6717 Sara Sea Circle, Siesta Key, FL
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $166 total per night from Oct 14 to Oct 15
$166 total
Oct 14 - Oct 15
Total with taxes and fees
9.2/10 Wonderful! (5,021 reviews)
"Everything was great. It was the cutest bungalow style studio. It has everything you needed, awesome little kitchenette, little indoor atrium, comfy bed, etc... The bathroom was tiny but clean. I would def stay here again."

Reviewed on Oct 9, 2025

Tropical Beach Resorts
Compass Hotel by Margaritaville Anna Maria Sound

Compass Hotel by Margaritaville Anna Maria Sound

4 out of 5
12324 Manatee Avenue West, Bradenton, FL
Fully refundableReserve now, pay when you stay
$203 nightly
The price is $229 total per night from Oct 19 to Oct 20
$229 total
Oct 19 - Oct 20
Total with taxes and fees
9.4/10 Exceptional! (1,787 reviews)
"Check in great, graded was our 7th anniversary"

Reviewed on Oct 8, 2025

Compass Hotel by Margaritaville Anna Maria Sound
See all 14,005 properties in Desoto Acres
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Desoto Acres

Lido Beach showing general coastal views and a sandy beach

Lido Beach

4.5/5(1,225 reviews)

Visit a beach not far from an upscale shopping area. The warm waters are as inviting as the white sand.

Lido Beach
Mall at University Town Center

Mall at University Town Center

4.5/5(363 reviews)

You can search for that perfect souvenir at Mall at University Town Center during your visit to Sarasota. Attend a sporting event or discover the beautiful sunsets in this family-friendly area.

Mall at University Town Center
St. Armands Circle featuring a statue or sculpture

St. Armands Circle

4.5/5(1,234 reviews)

Consider this area as a circular outdoor mall. Like any mall, you can shop, dine, browse or just people-watch. Unlike most malls, this one never closes to walkers.

St. Armands Circle

Things to do

Kayak Tour through Mangrove Tunnels

Mangroves, Manatees, and a Hidden Beach: Kayak Tour

$55
per adult
88% of travellers recommend
Mangroves, Manatees, and a Hidden Beach: Kayak Tour
Sarasota - Clear Kayak LED Night Glass Bottom Tour

Sarasota - Clear Kayak LED Night Glass Bottom Tour

$65
per adult
74% of travellers recommend
Sarasota - Clear Kayak LED Night Glass Bottom Tour
Anna Maria Island and Bradenton Beach: Parasailing Tour

Anna Maria Island & Bradenton Beach Parasailing Tour

$99
per adult
Anna Maria Island & Bradenton Beach Parasailing Tour
See all activities in Sarasota
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.