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Our top choices for Downtown hotels

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (682 reviews)
"Everting was good"
United States
Susan
$84 nightly
The price is $92
Mar 10 - Mar 11
Total with taxes and fees
Quality Inn Seneca Clemson Area US-123

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
10.1 mi from Downtown
10.0 out of 10, Exceptional, (83 reviews)
"The owners are amazing. Comfy rooms, stellar breakfast and good people. "
United States
Renee
$194 nightly
The price is $215
Mar 7 - Mar 8
Total with taxes and fees
Liberty Hall Bed and Breakfast

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
4.7 mi from Downtown
9.8 out of 10, Exceptional, (63 reviews)
"Excellent stay."
United States
Beonca
$109 nightly
The price is $120
Mar 4 - Mar 5
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
6.4 mi from Downtown
9.4 out of 10, Exceptional, (979 reviews)
"Everything was very nice "
United States
Paige
$149 nightly
The price is $165
Mar 8 - Mar 9
Total with taxes and fees
Clemson University's James F. Martin Inn

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
1.2 mi from Downtown
9.4 out of 10, Exceptional, (210 reviews)
"Spotless, friendly staff, great location. "
United States
Cari
$125 nightly
The price is $138
Mar 8 - Mar 9
Total with taxes and fees
Fairfield Inn & Suites Seneca Clemson Univ Area

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
8 mi from Downtown
7.6 out of 10, Good, (176 reviews)
"Older hotel with great staff. It was safe and provided a great place for a stop over on the way to TN. I would definitely stay here again. "
United States
Laura
$72 nightly
The price is $81
Apr 2 - Apr 3
Total with taxes and fees
Rodeway Inn & Suites Walhalla

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
9.5 mi from Downtown
9.8 out of 10, Exceptional, (801 reviews)
"Clean room, great location, wonderful staff!"
United States
Joyce
$149 nightly
The price is $165
Mar 8 - Mar 9
Total with taxes and fees
The Inn at Patrick Square

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
15.5 mi from Downtown
9.0 out of 10, Wonderful, (598 reviews)
"Clean, quiet, comfortable stay- staff is always friendly and helpful!"
United States
Lori
$93 nightly
The price is $103
Mar 22 - Mar 23
Total with taxes and fees
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
7.3 mi from Downtown
8.2 out of 10, Very Good, (1,009 reviews)
"Our room was very clean and the staff were very nice and courteous!"
United States
Tina
$91 nightly
The price is $101
Mar 8 - Mar 9
Total with taxes and fees
Best Western Plus Clemson Hotel & Conference Center

Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia
2.5 star property
19.1 mi from Downtown
9.0 out of 10, Wonderful, (390 reviews)
"Room was clean and staff was very friendly."
United States
clay
$130 nightly
The price is $155
Mar 22 - Mar 23
Total with taxes and fees
Hampton Inn & Suites Lavonia

Residence Inn by Marriott Anderson Clemson

Residence Inn by Marriott Anderson Clemson
3.0 star property
15.6 mi from Downtown
9.8 out of 10, Exceptional, (96 reviews)
"fabulous stay, great service and staff, excellent price, lovely amenities. "
United States
Corrina
$143 nightly
The price is $159
Mar 15 - Mar 16
Total with taxes and fees
Residence Inn by Marriott Anderson Clemson

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
1.9 mi from Downtown
6.8 out of 10, (728 reviews)
"Very nice and helpful at the fronte desk. Nice room and very comfortable bed"
United States
Crystal
$72 nightly
The price is $79
Mar 6 - Mar 7
Total with taxes and fees
Days Inn by Wyndham Seneca / Clemson Area

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
5.3 mi from Downtown
9.0 out of 10, Wonderful, (1,002 reviews)
"Great place and location, great mattress, "
United States
Jeffrey
$123 nightly
The price is $135
Mar 4 - Mar 5
Total with taxes and fees
Lakeside Lodge Clemson

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
6.3 mi from Downtown
9.6 out of 10, Exceptional, (569 reviews)
"Great stay"
United States
Megan
$179 nightly
The price is $199
Mar 4 - Mar 5
Total with taxes and fees
The Abernathy of Clemson

Inn @ Clemson

Inn @ Clemson
2.5 star property
7.2 mi from Downtown
8.2 out of 10, Very Good, (1,006 reviews)
"Staff and hotel was amazing "
United States
Keren
$84 nightly
The price is $94
Mar 4 - Mar 5
Total with taxes and fees
Inn @ Clemson

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
7.9 mi from Downtown
9.8 out of 10, Exceptional, (9 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
$224 nightly
The price is $249
Mar 8 - Mar 9
Total with taxes and fees
Clemson Memorabilia House

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
7.3 mi from Downtown
8.2 out of 10, Very Good, (1,001 reviews)
"Room was extremely clean, continental breakfast was amazing with many options, and staff were very friendly. Great hotel! "
United States
Delaney
$99 nightly
The price is $110
Mar 23 - Mar 24
Total with taxes and fees
Comfort Inn & Suites Clemson - University Area

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
15.9 mi from Downtown
9.0 out of 10, Wonderful, (703 reviews)
"Rooms were clean, staff were friendly, and we had 2 good night’s sleep."
United States
Sadie
$99 nightly
The price is $110
Mar 10 - Mar 11
Total with taxes and fees
Hilton Garden Inn Anderson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
5.2 mi from Downtown
9.2 out of 10, Wonderful, (813 reviews)
"Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!"
United States
Cindy
$114 nightly
The price is $125
Mar 10 - Mar 11
Total with taxes and fees
Tru by Hilton Seneca Clemson

Hampton Inn Anderson

Hampton Inn Anderson
2.5 star property
15.5 mi from Downtown
8.8 out of 10, Excellent, (413 reviews)
"EXCELLENT hotel and staff"
United States
Douglas
$114 nightly
The price is $126
Mar 29 - Mar 30
Total with taxes and fees
Hampton Inn Anderson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Seneca City Hall and Oconee County Library Seneca Branch.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Seneca City Hall and Oconee County Library Seneca Branch, some noteworthy sights in the nearby area.

Top Downtown Hotel Reviews

Frequently asked questions

What is Downtown like?
Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Seneca Historic District and Oconee County Library Seneca Branch as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on Expedia customer reviews, Quality Inn Seneca Clemson Area US-123 is the highest ranked property in Downtown. This hotel offers free breakfast and free parking.
How many hotels can I expect to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 12 hotels and other accommodations in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.
Where can I learn more about changing or cancelling my trip to Downtown?
To find more details about rescheduling or cancelling your trip to Downtown, head over to our customer service page.
What can I see and do in this Seneca neighborhood?
Seneca Historic District, Oconee County Library Seneca Branch, and Seneca City Hall are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Golden Corner Plaza, Oconee Community Theatre, and Applewood Shopping Center are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Wyndham Plaza or Cross Creek Plantation Golf.