A large lake surrounded by dense forests.

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Oct 23 - Oct 25
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Oct 30 - Nov 1

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Our top choices for Downtown hotels

A hotel dining area with a long table, multiple chairs, and a bar in the background.

1. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
1.4 mi from Downtown
9.2 out of 10, Wonderful, (759 reviews)
"Great place to stay when visiting Clemson!"
United States
Lloyd
$123 nightly
The price is $136
Oct 25 - Oct 26
Total with taxes and fees
Hampton Inn & Suites Seneca-Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.

2. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
1.2 mi from Downtown
9.4 out of 10, Exceptional, (286 reviews)
"Convenient location for doing business in seneca, and parts of clemson. The staff was wonderful. The breakfast was great."
United States
Lori
$120 nightly
The price is $132
Nov 1 - Nov 2
Total with taxes and fees
Fairfield Inn & Suites Seneca Clemson Univ Area
A restaurant interior with a counter, seating area, and a TV mounted on the wall.

3. Quality Inn Seneca US-123

Quality Inn Seneca US-123
2.5 star property
2.4 mi from Downtown
8.0 out of 10, Very good, (760 reviews)
"Clean rooms clean parking area nice staff all good"
United States
Barry
$90 nightly
The price is $98
Oct 20 - Oct 21
Total with taxes and fees
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

4. Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
1 mi from Downtown
8.4 out of 10, Very good, (693 reviews)
"Friendly staff, comfortable bed"
United States
Michelle
$94 nightly
The price is $103
Oct 20 - Oct 21
Total with taxes and fees
Best Western Seneca-Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.

5. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
1.9 mi from Downtown
6.8 out of 10, (788 reviews)
"Staff were nice and accommodating"
United States
Rosario
$72 nightly
The price is $79
Oct 22 - Oct 23
Total with taxes and fees
Days Inn by Wyndham Seneca / Clemson Area
An outdoor patio area with a fire pit, seating, and string lights.

6. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
5.2 mi from Downtown
9.2 out of 10, Wonderful, (900 reviews)
"Great stay!"
United States
Melissa
$111 nightly
The price is $122
Nov 8 - Nov 9
Total with taxes and fees
Tru by Hilton Seneca Clemson
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

7. Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
5.3 mi from Downtown
9.0 out of 10, Wonderful, (1,004 reviews)
"Great location. Amenities were spot on restaurant staff excellent!"
United States
Lori
$123 nightly
The price is $135
Oct 19 - Oct 20
Total with taxes and fees
Lakeside Lodge Clemson
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

8. The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
6.3 mi from Downtown
9.6 out of 10, Exceptional, (654 reviews)
"Very conveniently located to Clemson and well maintained. We enjoyed having an afternoon beverage at the bar and grabbing a quick bite to eat in the morning. Hallways were quiet and I appreciated the bathroom amenities and robes too. I would definitely recommend staying here."
United States
Amy
$149 nightly
The price is $165
Nov 17 - Nov 18
Total with taxes and fees
The Abernathy of Clemson
A golf course with a water body, trees, and a distant view of a bridge.

9. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
6.4 mi from Downtown
9.4 out of 10, Exceptional, (1,001 reviews)
"Great property!"
United States
Lilllian
$149 nightly
The price is $165
Oct 18 - Oct 19
Total with taxes and fees
Clemson University's James F. Martin Inn
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

10. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
4.7 mi from Downtown
9.8 out of 10, Exceptional, (113 reviews)
"My wife and I enjoyed our stay here. 10/10 experience."
United States
Winston
$133 nightly
The price is $146
Nov 16 - Nov 17
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A modern kitchen area with a bar counter and seating.

11. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
6.1 mi from Downtown
8.8 out of 10, Excellent, (651 reviews)
"Staff was great especially Crystal. Breakfast was fine. A little hidden by trees so watch out or you could miss entrance. Also, driveway just a little steep to get into lot but once there everything was fine. "
United States
Blaise
$110 nightly
The price is $122
Oct 26 - Oct 27
Total with taxes and fees
Hampton Inn Clemson-University Area
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

12. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
7.3 mi from Downtown
8.0 out of 10, Very good, (1,004 reviews)
"Great place to stay."
United States
David
$105 nightly
The price is $117
Nov 16 - Nov 17
Total with taxes and fees
Best Western Plus Clemson Hotel & Conference Center
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

13. Inn @ Clemson

Inn @ Clemson
2.5 star property
7.2 mi from Downtown
8.0 out of 10, Very good, (1,000 reviews)
"Clean room, comfortable beds, good breakfast, great price!"
United States
Kristi
$73 nightly
The price is $81
Oct 27 - Oct 28
Total with taxes and fees
Inn @ Clemson
Room

14. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
7.3 mi from Downtown
8.4 out of 10, Very good, (1,002 reviews)
"We will stay here again if we go to Clemson. Room was excellent...staff was excellent and the breakfast room and food was excellent!"
United States
Beverly
$105 nightly
The price is $117
Nov 15 - Nov 16
Total with taxes and fees
Comfort Inn & Suites Clemson - University Area
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

15. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
7.7 mi from Downtown
8.8 out of 10, Excellent, (998 reviews)
"Wonderful place to stay."
United States
John
$129 nightly
The price is $143
Oct 25 - Oct 26
Total with taxes and fees
Holiday Inn Express & Suites Clemson by IHG
A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

16. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
3.5 star property
7.7 mi from Downtown
6.8 out of 10, (235 reviews)
"Very overpriced for a basic hotel. Obviously survives on game day and big events in Clemson."
United States
David
$80 nightly
The price is $89
Oct 18 - Oct 19
Total with taxes and fees
Days Inn by Wyndham Clemson
A modern bar area with a menu board, bar stools, and a countertop with various items.

17. Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
8 mi from Downtown
9.0 out of 10, Wonderful, (588 reviews)
"The staff were so friendly and accommodating. The property was very clean and room was spacious."
United States
kim
$111 nightly
The price is $123
Nov 1 - Nov 2
Total with taxes and fees
Courtyard Marriott Clemson
A kitchen with a coffee maker, microwave, and refrigerator.

18. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
8 mi from Downtown
7.6 out of 10, Good, (198 reviews)
"Good value for the price. Bed was comfortable and the price was good"
United States
Richard
$72 nightly
The price is $81
Nov 16 - Nov 17
Total with taxes and fees
Rodeway Inn & Suites Walhalla
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

19. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
6.6 mi from Downtown
9.8 out of 10, Exceptional, (899 reviews)
"Always a wonderful stay!"
United States
Laurrie
$186 nightly
The price is $206
Oct 18 - Oct 19
Total with taxes and fees
The Shepherd Hotel Downtown Clemson
A hotel lobby with a reception desk, seating area, and a view of the street outside.

20. Econo Lodge Clemson - University Area

Econo Lodge Clemson - University Area
2.0 star property
8.1 mi from Downtown
7.2 out of 10, Good, (160 reviews)
"Good location . Good price. Nice and quiet. Unusually good tv show choices. (Much better than last 4 or 5 hotels that I stayed at!)"
United States
Ruth
$73 nightly
The price is $80
Oct 25 - Oct 26
Total with taxes and fees
Econo Lodge Clemson - University Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels recommended for families in Downtown

A hallway with a wooden floor, a large mirror, and framed pictures on the walls.

Boutique hotel in historic downtown Seneca. Room #5, two King beds.

Boutique hotel in historic downtown Seneca. Room #5, two King beds.
Downtown
9.4 out of 10, Exceptional, (20)
$188 nightly
The price is $204
Oct 19 - Oct 20
Total with taxes and fees
Boutique hotel in historic downtown Seneca. Room #5, two King beds.

Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most.
A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, South Beach and Lake Keowee are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Keowee Reservoir.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Keowee Reservoir, some noteworthy sights in the nearby area.

Top Downtown Hotel Reviews

Lakeside Lodge Clemson

Lakeside Lodge Clemson

10/10 Excellent
"Excellent stay. Very beautiful property, room was clean and comfortable. Staff was very friendly and helpful. We had a wonderful dinner at the onsite restaurant. Would definitely stay again if in the area."
Ann 1-night trip
Posted 3 hours ago
Lakeside Lodge Clemson

Frequently asked questions

What is Downtown like?
Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Oconee County Library Seneca Branch and Blue Ridge Arts Center as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
For your stay in Downtown, Historic Seneca Bungalow is one of the top choices based on our traveler data.
How many hotels can I expect to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 12 hotels and other accommodations in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.
Where can I learn more about changing or cancelling my trip to Downtown?
To find more details about rescheduling or cancelling your trip to Downtown, head over to our customer service page.
What can I see and do in this Seneca neighborhood?
Oconee County Library Seneca Branch, Blue Ridge Arts Center, and Seneca Historic District are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza, and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Applewood Shopping Center or Wyndham Plaza.