Seneca Vacation Rentals

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Check prices for these dates

In two weeks
Feb 6 - Feb 8
In two months
Mar 20 - Mar 22
In three months
Apr 17 - Apr 19
In four months
May 15 - May 17

Our top choices for Seneca vacation rentals

Exterior

Cabin in Seneca

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
9.8 out of 10, Exceptional, (55 reviews)
"Excellent stay."
United States
Beonca
$129 nightly
The price is $142
Jan 21 - Jan 22
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Private kitchen

Vacation Home in Seneca

The Clemson Cottage - 3.6 mi. to Memorial Stadium
10.0 out of 10, Exceptional, (12 reviews)
"Adorable and clean home convenient to Clemson’s campus. We enjoyed our stay and Tyler was an exceptional host! "
United States
Mandy H.
$360 nightly
The price is $396
Jan 21 - Jan 22
Total with taxes and fees
The Clemson Cottage - 3.6 mi. to Memorial Stadium
Smart TV, video games, table tennis

Condo in Seneca

Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
10.0 out of 10, Exceptional, (21 reviews)
"Very nice accommodations and great location for stay in Clemson. "
United States
Marisa G.
$313 nightly
The price is $344
Jan 21 - Jan 22
Total with taxes and fees
Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
Exterior

Cabin in Seneca

Cozy Clemson TIny House Cabin
2.0 star property
$197 nightly
The price is $217
Jan 21 - Jan 22
Total with taxes and fees
Cozy Clemson TIny House Cabin
Living area

Camping in Seneca

So Mushroom Silver Streak Travel Trailer
2.0 star property
$144 nightly
The price is $159
Jan 21 - Jan 22
Total with taxes and fees
So Mushroom Silver Streak Travel Trailer
Microwave, oven, stovetop, dishwasher

Vacation Home in Seneca

The Big Golf House- 10 miles to Clemson
10.0 out of 10, Exceptional, (2 reviews)
"Absolutely! Perfect space for our needs, so for accommodating for our family & pet. "
United States
Gennifer Q.
$498 nightly
The price is $541
Jan 21 - Jan 22
Total with taxes and fees
The Big Golf House- 10 miles to Clemson
Interior

Vacation Home in Seneca

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
9.6 out of 10, Exceptional, (8 reviews)
"Owner was on point with contact prior to arrival and during stay. Check in was super easy and property was clean and decorated nicely. Everything that we needed was already at the house. There is a marina close by with restaurant also."
United States
Benjamin J.
$657 nightly
The price is $695
Jan 21 - Jan 22
Total with taxes and fees
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Smart TV

Vacation Home in Seneca

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
8.0 out of 10, Very Good, (3 reviews)
"Everything was in great condition! Items provided were good quality. You can tell a lot of time and thought has been put into this property. We would love to stay again. "
United States
Alisa W.
$264 nightly
The price is $290
Jan 21 - Jan 22
Total with taxes and fees
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
1 bedroom, WiFi, bed sheets

Camping in Seneca

Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
10.0 out of 10, Exceptional, (12 reviews)
"Very clean and comfortable - very close to Clemson and easy access. "
United States
Jim A.
$181 nightly
The price is $199
Jan 21 - Jan 22
Total with taxes and fees
Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!
Fridge, microwave, oven, stovetop

Vacation Home in Seneca

3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
10.0 out of 10, Exceptional, (5 reviews)
"Great place with a lot close by"
United States
Aldor D.
$289 nightly
The price is $317
Jan 22 - Jan 23
Total with taxes and fees
3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
4 bedrooms, desk, iron/ironing board, WiFi

Vacation Home in Seneca

Johnsons Cove - Lakefront Retreat With EV Charger
10.0 out of 10, Exceptional, (1 review)
"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."
United States
Rebecca G.
$749 nightly
The price is $795
Jan 21 - Jan 22
Total with taxes and fees
Johnsons Cove - Lakefront Retreat With EV Charger
Property grounds

Vacation Home in Serenity Bay

Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger
9.8 out of 10, Exceptional, (130 reviews)
"A wonderful stay! The house offered many different spaces and the lake access/dock was perfect!!"
United States
stacy s.
$566 nightly
The price is $623
Jan 21 - Jan 22
Total with taxes and fees
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger
Interior

Vacation Home in Seneca

Timber Trail Estate: Stunning Views + Waterfront
2.0 star property
6.4 out of 10, (5 reviews)
"Main floor was clean but basement and loft, cleaners missed a lot. It was very dusty with lots of cobwebs. Cleaners have missed a lot of places over and over again. The downstairs deck was full of pollen and so dirty we couldn’t sit out there. Wish there was an umbrella on top deck- no shade or cover when rains. Wish there was somewhere to put suitcases but w no closet space and no dresser tops, suitcases were all over floors. Was just hoping for a cleaner space for what we paid. Overall it was...
United States
Kristen F.
$468 nightly
The price is $532
Jan 21 - Jan 22
Total with taxes and fees
Timber Trail Estate: Stunning Views + Waterfront
Interior

Mobile Home in Westminster

Glamping with a partial lake view, 30 minutes to Clemson University
9.4 out of 10, Exceptional, (14 reviews)
"The camper was very clean and the set up was very nice. Didn’t have a view of the lake, but all in all had a very nice stay. "
United States
Scott S.
$189 nightly
The price is $208
Jan 26 - Jan 27
Total with taxes and fees
Glamping with a partial lake view, 30 minutes to Clemson University
Cabin, 2 Bedrooms, Non Smoking (No Pets, Linens Included) | In-room dining

Mobile Home in Fair Play

Carolina Landing RV Resort - Caravan Park
2.0 star property
7.6 out of 10, Good, (47 reviews)
"Lake "
United States
Milton
$130 nightly
The price is $143
Feb 11 - Feb 12
Total with taxes and fees
Carolina Landing RV Resort - Caravan Park
Smart TV

Mobile Home in Pendleton

The Pendle-Tin
9.8 out of 10, Exceptional, (9 reviews)
"Perfect for weekend getaway!"
United States
Gregg H.
$177 nightly
The price is $196
Feb 2 - Feb 3
Total with taxes and fees
The Pendle-Tin
Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix

Cottage in Clemson

Clemson Memorabilia House
3.0 star property
9.8 out of 10, Exceptional, (9 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
$214 nightly
The price is $238
Jan 21 - Jan 22
Total with taxes and fees
Clemson Memorabilia House
Interior

Apartment in Clemson

Ballgame Bungalow, Entire 2BR/2BA Apt in Clemson
9.2 out of 10, Wonderful, (9 reviews)
"We had a great stay in this clean and centrally located two bedroom place - including quick communication with the property managers when we had some problems with the WiFi! Loved the location, will absolutely visit again. "
United States
Agatha L.
$327 nightly
The price is $351
Jan 21 - Jan 22
Total with taxes and fees
Ballgame Bungalow, Entire 2BR/2BA Apt in Clemson
Outdoor spa tub

Cottage in Anderson

Lake Hartwell cottage - Hot Tub! ~we have no lake water till it rains
9.8 out of 10, Exceptional, (82 reviews)
"This house was perfect for our family for the weekend, very comfortable and peaceful. The house had everything we needed and more, and hot was very thoughtful and communicative. We enjoyed kayaking on the lake and hiking in the area, would stay here again."
United States
Corrie H.
$243 nightly
The price is $270
Jan 21 - Jan 22
Total with taxes and fees
Lake Hartwell cottage - Hot Tub! ~we have no lake water till it rains
Exterior

Cottage in Townville

Broyles Landing Cottage at Lake Hartwell SC
10.0 out of 10, Exceptional, (17 reviews)
"Easy check in, the place was stocked with awesome snacks we werent expecting. The cots were very comfortable. "
United States
Damian D.
$178 nightly
The price is $198
Jan 21 - Jan 22
Total with taxes and fees
Broyles Landing Cottage at Lake Hartwell SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"Awesome hotel and very convenient for visiting Clemson."
Nina 1-night trip
Posted 3 days ago
The Shepherd Hotel Downtown Clemson

Find out more about Seneca

Everything you need to know about Seneca vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Seneca vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Seneca vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Seneca vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Seneca. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Seneca in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $142 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Seneca rentals

At Expedia, we put the best Seneca vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Seneca rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Seneca vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Seneca. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Seneca?

Yes, there are vacation rentals close to popular attractions in Seneca, or you can select a secluded option if you'd like a relaxing place to stay. Discover why Seneca is known for its marina and lakeside. While you're here, grab a bite or have a drink at the coffeehouses.

What's the top vacation rental in Seneca?

Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock: This highly rated vacation home rental in Seneca is located on a lake and has a patio, a private yard, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Some other homes for rent in Seneca include Luxury 4BR/4BA Lake Keowee Retreat- Mountain Cabin Vibes + Private Dock and Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub.

How many vacation rentals are there in Seneca?

Choose from 189 Expedia vacation rentals in Seneca for a memorable vacation.

What’s there to see and do in Seneca?

Cultural attractions include The Gauntlet and Oconee Community Theatre, whereas Keowee Reservoir and Lake Keowee are a couple of picturesque spots to enjoy the outdoors. While here, Keowee Key Golf Course and Lake Hartwell are other places worth a visit.

What’s a vacation rental in Seneca like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Seneca. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll have all the conveniences of home. If you're concerned about cleanliness, vacation rentals can provide a sense of security away from shared hotel elevators and busy concierge desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family trips.