Name: Ortea Palace Hotel, Sicily, Autograph Collection
Price range: $450 total

Your Epipoli Vacation

Reserving a tailor-made Epipoli vacation package is a wonderful way to become familiar with this neighborhood. From its must-see spots to its lesser-known delights, you won't be short of new adventures. When it's time to get out and explore, you'll find a lot of popular attractions nearby including Cathedral of Syracuse, Temple of Apollo and Castello Eurialo. Visit one, two or more during your trip to Epipoli. Expedia will help you turn your ideal Epipoli vacation into reality, no matter your budget or travel plans.

The Latest Epipoli Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Continental

Taormina City Centre

$1,243

per person

Aug 26 - Aug 30

found 13 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Catania (CTA)

9.2/10 Wonderful! (658 reviews)

Excellent for location - two minutes to the main Corso and with a fabulous terrace overlooking Etna.

Reviewed on Jul 17, 2026

Wellness & Spa Hotel Principe di Fitalia

Save 100% on your flight

$2,145

per person

Sep 19 - Sep 25

found 1 day ago

Roundtrip non-stop flight included

New York (NYC) to Catania (CTA)

9.6/10 Exceptional! (96 reviews)

A very well maintained hotel. An excellent pool. Incredibly helpful staff even though we speak very limited Italian and an exceptional breakfast.

Reviewed on Jul 12, 2026

Duomo Suites & Spa

Catania City Centre

Save 100% on your flight

$2,558

per person

Sep 20 - Sep 25

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Catania (CTA)

9/10 Wonderful! (451 reviews)

I Love this hotel, please get Smart TV with YouTube and Netflix, I only stayed one night, I looked for accommodation with Smart TV for my next 3 days, please 🙏 I would like to stay in your hotel, Please get Smart TV 🙏

Reviewed on Jul 17, 2026

The Ashbee Hotel - The Leading Hotels of the World

Save 100% on your flight

$4,578

per person

Sep 20 - Sep 23

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Catania (CTA)

9.2/10 Wonderful! (139 reviews)

Hotel Elios

$1,427

per person

Aug 27 - Aug 31

found 1 day ago

Roundtrip non-stop flight included

New York (JFK) to Catania (CTA)

7/10 Good! (29 reviews)

I liked where it was located with a gorgeous view, very friendly staff, and a great room for resting! I would stay again!

Reviewed on May 26, 2026

Where to stay in Epipoli

Find the best Epipoli areas and neighborhoods for the activities you enjoy most. Learn more about Epipoli

Ancient ruins with stone columns and a building with green shutters in the background.

Ortigia

4 out of top 10 points of interest in this area

The historic heart of Syracuse is dotted with churches and atmospheric piazzas, where visitors enjoy sweeping sea views while dining at gourmet restaurants.

Epipoli Hotel Deals

Mangia's Brucoli, Sicily, Autograph Collection

Contrada Gisira 1 Augusta SR

Fully refundableReserve now, pay when you stay

$327 nightly

$371 total

Jul 24 - Jul 25

Total with taxes and fees

8.6/10 Excellent! (140 reviews)

"Staff is amazing!"

Reviewed on Jul 8, 2026

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR

Fully refundableReserve now, pay when you stay

$197 nightly

$228 total

Jul 20 - Jul 21

Total with taxes and fees

9.6/10 Exceptional! (993 reviews)

"Wow! This hotel is exceptional. The staff are kind, patient, and helpful. The breakfast is very good. The location is fantastic! Would return in a heartbeat."

Reviewed on Jul 17, 2026

Ortea Palace Hotel, Sicily, Autograph Collection

Via Riva Nazario Sauro Syracuse SR

Fully refundableReserve now, pay when you stay

$398 nightly

$450 total

Aug 1 - Aug 2

Total with taxes and fees

See all 3,896 properties in Epipoli

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.