Skip to main content
A 4-way stop sign, a building with a sign reading "First Bank," and a brick building with a large window.
Photo by Erik Rowley
Open Photo by Erik Rowley

Guthrie County Vacations & Trips from $288

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Top destinations in Guthrie County

A rural road flanked by wind turbines and fields.
FlightsHotels

Stuart

Stuart

The Latest Guthrie County Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
    Oct 1 - Oct 4

    Sonesta Simply Suites Des Moines + Flight

    West Des Moines
    3 nights
    2.5 star property
    8.2/10 - Very Good (1,007 reviews)
    "Great room"
    Reviewed August 5, 2026
    Roundtrip • Denver (DEN) - Des Moines (DSM)
    DEN - DSM • Nonstop DSM - DEN • Nonstop
    $345
    $288
    per traveler
    found 1 day ago
    Sonesta Simply Suites Des Moines
  • Dinner served
    Oct 1 - Oct 4

    Hotel Fort Des Moines, Curio Collection by Hilton + Flight

    Downtown Des Moines
    3 nights
    4.5 star property
    9.6/10 - Exceptional (1,257 reviews)
    "Beautiful historical hotel that was up to date and clean!"
    Reviewed August 5, 2026
    Roundtrip • Denver (DEN) - Des Moines (DSM)
    DEN - DSM • Nonstop DSM - DEN • Nonstop
    $814
    $663
    per traveler
    found 1 day ago
    Hotel Fort Des Moines, Curio Collection by Hilton
  • Indoor pool
    Oct 1 - Oct 4

    La Quinta by Wyndham Altoona Des Moines + Flight

    Altoona
    3 nights
    3.0 star property
    9.0/10 - Wonderful (1,406 reviews)
    "La Quinta in Altoona was clean and generally very nice. There were a few items that could be improved: 1) There was no light on the side of the our room near the bathroom. A floor lamp there would really help. 2) We are older people and were fortunate that we brought along a bath mat. Otherwise the tub (which we used only as a shower) would have been very slick and difficult to get out of. 3) The faucet for the bathroom sink was mounted away from the basin and whenever you used it water bounced..."
    Reviewed August 6, 2026
    Roundtrip • Denver (DEN) - Des Moines (DSM)
    DEN - DSM • Nonstop DSM - DEN • Nonstop
    $425
    $362
    per traveler
    found 1 day ago
    La Quinta by Wyndham Altoona Des Moines
  • Reception
    Oct 7 - Oct 13

    Hampton Inn West Des Moines Lake Drive + Flight

    West Des Moines
    6 nights
    3.0 star property
    8.8/10 - Excellent (1,005 reviews)
    Roundtrip • Phoenix (PHX) - Des Moines (DSM)
    PHX - DSM • Nonstop DSM - PHX • Nonstop
    $1,058
    $903
    per traveler
    found 1 day ago
    Hampton Inn West Des Moines Lake Drive
  • Terrace/patio
    Oct 7 - Oct 13

    Qube Hotel + Flight

    Polk City
    6 nights
    2.5 star property
    8.4/10 - Very Good (758 reviews)
    "Nice location on a beautiful golf course. Cute town within 1/2 mile. A few restaurants and an adorable ice cream shop. Huge lake with beach nearby. Fire places on the front and back decks. Vending machines, ice machine, and laundry available. Spacious room. Very comfy beds. Quiet over night. Breakfast 4 juice choices, waffle maker, toaster, packaged sweet rolls (Hostess donuts, danish...), yogurt, fresh fruit, coffee, and milk."
    Reviewed August 5, 2026
    Roundtrip • Phoenix (PHX) - Des Moines (DSM)
    PHX - DSM • Nonstop DSM - PHX • Nonstop
    $789
    $674
    per traveler
    found 1 day ago
    Qube Hotel

Guthrie County Hotel Deals

Reception

Midway Motel

Midway Motel
2.5 star property
1 mi from Guthrie County
9.0 out of 10, Wonderful, (36 reviews)
"The property is a typical 1950's style hotel that has been remodeled. The beds were clean and comfortable. It comes with a fridge/freezer and microwave. The only amenities are very cheap bar soap and shampoo. No hair dryer, conditioner or body wash. Breakfast is not included. I felt it was very expensive for what you got"
$95 nightly
The price is $100
Aug 7 - Aug 8
Total with taxes and fees
Midway Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in Guthrie County
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.