Guthrie County Vacations & Trips from $416

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Your Guthrie County Vacation

Make planning your next big adventure a piece of cake with a Guthrie County vacation package. Whether it's the food scene, history or something else that brings you here, our package deals will help you discover it all. A trip to Guthrie County is a terrific opportunity to tour its leading cities. Panora and Coon Rapids are a couple that should be on everyone's travel itinerary. If you're ready to stop dreaming and start discovering, Expedia will help turn your Guthrie County vacation into a reality.

Top destinations in Guthrie County

A rural road flanked by wind turbines and fields.

Stuart

Stuart
A covered bridge with a white railing, surrounded by trees and grass.

Adair

Adair
A calm lake reflecting trees with autumn foliage.

Guthrie Center

Guthrie Center

The Latest Guthrie County Vacation Packages

Price found within the past 48 hours. Click for updated prices.
SpringHill Suites Des Moines West

SpringHill Suites Des Moines West

$416
per person
Nov 6 - Nov 9
found 24 hours ago
Roundtrip non-stop flight included
Los Angeles (QLA) to Des Moines (DSM)
8.6/10 Excellent! (1,006 reviews)
Wildwood Lodge

Wildwood Lodge

$786
per person
Nov 24 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
Daytona Beach (DAB) to Des Moines (DSM)
9.6/10 Exceptional! (1,213 reviews)
Lodge was very quiet even on Saturday night. Warm, cozy feeling throughout the hotel. Staff very knowledgable and helpful.

Reviewed on Sep 19, 2026

AmericInn by Wyndham Ankeny/Des Moines

AmericInn by Wyndham Ankeny/Des Moines

$700
per person
Nov 24 - Nov 28
found 2 hours ago
Roundtrip non-stop flight included
Daytona Beach (DAB) to Des Moines (DSM)
8/10 Very Good! (942 reviews)
Surpassed my expectations traveling with family and there was room for all in the king suite! The staff were very polite and accommodating during our stay!! Perfect choice especially if traveling with family!

Reviewed on Sep 19, 2026

GrandStay Hotel & Suites

GrandStay Hotel & Suites

$714
per person
Nov 24 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
Daytona Beach (DAB) to Des Moines (DSM)
9.2/10 Wonderful! (793 reviews)
New place ,everything was great .Issue with key and door . Could use more proteins.I will look for more GrandStay for my next trip.

Reviewed on Sep 20, 2026

My Place Hotel - Ankeny/ Des Moines, IA

My Place Hotel - Ankeny/ Des Moines, IA

$711
per person
Nov 24 - Nov 28
found 2 hours ago
Roundtrip non-stop flight included
Daytona Beach (DAB) to Des Moines (DSM)
9/10 Wonderful! (830 reviews)
Clean room with a mini kitchen. Great value.

Reviewed on Sep 12, 2026

Find the Best Guthrie County Vacation Packages

Guthrie County Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Des Moines Intl. Airport (DSM)

Guthrie County Hotel Deals

Midway Motel

Midway Motel

2301 State St Guthrie Center IA
$96 nightly
$100 total
Oct 21 - Oct 22
Total with taxes and fees
Midway Motel
Rustic cottage in river valley with access to hiking and mountain biking trails

Rustic cottage in river valley with access to hiking and mountain biking trails

Coon Rapids IA
10/10 Exceptional! (75 reviews)
"Awesome place to stay"

Reviewed on Jul 31, 2026

Get rates
Rustic cottage in river valley with access to hiking and mountain biking trails
Lake Panorama Studio

Lake Panorama Studio

Panora IA
Lake Panorama Studio
See all 105 properties in Guthrie County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Guthrie County attractions

Sheeder Prairie State Preserve

8.0/10 (4 reviews)
Explore the great outdoors at Sheeder Prairie State Preserve, a lovely green space in Guthrie Center.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.