A 4-way stop sign, a building with a sign reading "First Bank," and a brick building with a large window.
Photo by Erik Rowley
Open Photo by Erik Rowley

Guthrie County Vacations & Trips from $400

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Your Guthrie County Vacation

Make planning your next big adventure a piece of cake with a Guthrie County vacation package. Whether it's the food scene, history or something else that brings you here, our package deals will help you discover it all. A trip to Guthrie County is a terrific opportunity to tour its leading cities. Panora and Coon Rapids are a couple that should be on everyone's travel itinerary. If you're ready to stop dreaming and start discovering, Expedia will help turn your Guthrie County vacation into a reality.

Top destinations in Guthrie County

A rural road flanked by wind turbines and fields.
FlightsHotels

Stuart

Stuart

The Latest Guthrie County Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • An indoor swimming pool with a waterfall feature, surrounded by Adirondack chairs and a wooden deck.
    Dec 7 - Dec 9

    Stoney Creek Hotel Des Moines - Johnston + Flight

    Johnston
    2 nights
    2.5 star property
    8.8/10 - Excellent (1,933 reviews)
    "Woke up to a mouse running through the room and staff didn’t seem concerned when reported."
    Reviewed November 5, 2026
    Roundtrip • Austin (AUS) - Des Moines (DSM)
    AUS - DSM • 1 stop DSM - AUS • 1 stop
    $442
    $400
    per traveler
    found 1 day ago
    Stoney Creek Hotel Des Moines - Johnston
  • A building with a stone facade, multiple windows, and outdoor seating with tables and chairs.
    Dec 6 - Dec 10

    Qube Hotel + Flight

    Polk City
    4 nights
    2.5 star property
    8.4/10 - Very good (831 reviews)
    Roundtrip • Seattle (SEA) - Des Moines (DSM)
    SEA - DSM • 1 stop DSM - SEA • 1 stop
    $639
    $573
    per traveler
    found 10 hours ago
    Qube Hotel
  • A spacious lobby with high ceilings, large windows, and a chandelier.
    Dec 7 - Dec 9

    Hotel Fort Des Moines, Curio Collection by Hilton + Flight

    Downtown Des Moines
    2 nights
    4.5 star property
    9.6/10 - Exceptional (1,412 reviews)
    Roundtrip • Austin (AUS) - Des Moines (DSM)
    AUS - DSM • 1 stop DSM - AUS • 1 stop
    $505
    $461
    per traveler
    found 1 day ago
    Hotel Fort Des Moines, Curio Collection by Hilton
  • A hotel room with two beds, a TV, a window with blinds, a framed picture on the wall, and a bedside lamp.
    Dec 6 - Dec 10

    My Place Hotel - Altoona/Des Moines, IA + Flight

    Altoona
    4 nights
    3.0 star property
    8.8/10 - Excellent (1,002 reviews)
    Roundtrip • Seattle (SEA) - Des Moines (DSM)
    SEA - DSM • 1 stop DSM - SEA • 1 stop
    $579
    $530
    per traveler
    found 10 hours ago
    My Place Hotel - Altoona/Des Moines, IA
  • A spacious lobby with a high ceiling, a central seating area with a blue sofa and chairs, a dining area, and a staircase leading to an upper level.
    Dec 6 - Dec 10

    Fairfield Inn and Suites by Marriott Des Moines West + Flight

    West Des Moines
    4 nights
    3.0 star property
    9.0/10 - Wonderful (1,005 reviews)
    Roundtrip • Seattle (SEA) - Des Moines (DSM)
    SEA - DSM • 1 stop DSM - SEA • 1 stop
    $631
    $589
    per traveler
    found 10 hours ago
    Fairfield Inn and Suites by Marriott Des Moines West

Discover the most popular places to visit in Guthrie County

Sheeder Prairie State Preserve

8.0/10 (4 reviews)
Explore the great outdoors at Sheeder Prairie State Preserve, a lovely green space in Guthrie Center.
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Guthrie County Hotel Deals

A room with a large mirror, a Christmas tree, and string lights.

Midway Motel

Midway Motel
2.5 star property
1 mi from Guthrie County
8.8 out of 10, Excellent, (38 reviews)
"The property is a typical 1950's style hotel that has been remodeled. The beds were clean and comfortable. It comes with a fridge/freezer and microwave. The only amenities are very cheap bar soap and shampoo. No hair dryer, conditioner or body wash. Breakfast is not included. I felt it was very expensive for what you got"
$99 nightly
The price is $104
Nov 20 - Nov 21
Total with taxes and fees
Midway Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in Guthrie County
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.