Title: Istia d'Ombrone Vacation Packages 2026 from $1,350 | Expedia.com [Istia d'Ombrone Travel Guide](https://expedia.com/Istia-DOmbrone.dx6361369)[Hotels in Istia d'Ombrone](https://expedia.com/Istia-DOmbrone-Hotels.d6361369.Travel-Guide-Hotels)[Vacation Rentals in Istia d'Ombrone](https://expedia.com/Istia-DOmbrone-Vacation-Rentals.d6361369.Travel-Guide-VacationRentals)[Flights to Istia d'Ombrone](https://expedia.com/Cheap-Flights-To-Istia-DOmbrone.d6361369.Travel-Guide-Flights)[Car Rentals in Istia d'Ombrone](https://expedia.com/Car-Rentals-In-Istia-DOmbrone.d6361369.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Istia d'Ombrone Vacations from $1,350 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Istia dOmbrone Vacation Build a custom vacation package to Istia dOmbrone and get ready for your next big adventure. Consider staying in the neighborhood of Marina di Grosseto, which is great for watersports and coastal beaches, for a real taste of this vibrant city. A trip to Istia dOmbrone is an ideal opportunity to do some sightseeing. Be sure to visit renowned attractions like [Roselle Archaeological Area](https://www.expedia.com/Roselle-Archaeological-Area-Grosseto.d6291801.Vacation-Attraction), [Piazza Stefano de Maria](https://www.expedia.com/Piazza-Stefano-De-Maria-Grosseto.d6291796.Vacation-Attraction) and [Court of Grosseto](https://www.expedia.com/Court-Of-Grosseto-Grosseto.d553248635975698127.Vacation-Attraction). A couple of quick clicks is all it takes to build your perfect Istia dOmbrone vacation on Expedia. ## The Latest Istia d'Ombrone vacation packages Price found within the past 48 hours. Click for updated prices. ![Eurostars Florence Boutique](https://images.trvl-media.com/lodging/2000000/1170000/1167000/1166901/10f2f159_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Eurostars Florence Boutique Historic Centre of Florence $1,350 per person May 13 - May 18 found 1 day ago Roundtrip non-stop flight included Newark Liberty Intl. Airport (EWR) to Florence (FLR) 8.6/10 Excellent! (476 reviews) The room was clean and the staff very accommodating. The breakfast was quite sufficient and had a good variety. The location is great. It's a short walk from the square, shopping and from restaurants. Reviewed on Dec 13, 2025 ![Aurum Uffizi](https://images.trvl-media.com/lodging/3000000/2550000/2541700/2541615/862ad26c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Aurum Uffizi Historic Centre of Florence $2,166 per person Apr 19 - Apr 25 found 1 day ago Roundtrip non-stop flight included Boston (BOS) to Florence (FLR) 7.8/10 Good! (1,000 reviews) Smaller room then expected and shower did flood the floor so not the best of showers. Bed very comfortable Nice friendly & helpful staff and perfect location to explore the city. Reviewed on Feb 22, 2026 ![Grand Hotel Cavour](https://images.trvl-media.com/lodging/1000000/20000/11000/10993/50470bbc_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Grand Hotel Cavour Historic Centre of Florence $1,706 per person May 8 - May 12 found 1 day ago Roundtrip non-stop flight included San Francisco (SFO) to Florence (FLR) 9.2/10 Wonderful! (1,002 reviews) Everyone is so nice and helpful! It was also in a great location with an amazing rooftop picturing the entire city. Reviewed on Feb 20, 2026 ![Hotel degli Orafi](https://images.trvl-media.com/lodging/1000000/980000/970900/970861/126e440f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel degli Orafi Historic Centre of Florence $1,398 per person May 18 - May 22 found 1 day ago Roundtrip non-stop flight included New York (NYC) to Florence (FLR) 9.6/10 Exceptional! (1,001 reviews) Room immaculate, staff always so helpful, the rooftop bar has incredible views, wouldn’t stay anywhere else! Reviewed on Feb 24, 2026 ![Hotel La Scaletta Al Ponte Vecchio](https://images.trvl-media.com/lodging/2000000/1610000/1604300/1604285/9b3b942d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel La Scaletta Al Ponte Vecchio Historic Centre of Florence $1,666 per person May 13 - May 18 found 1 day ago Roundtrip non-stop flight included Newark Liberty Intl. Airport (EWR) to Florence (FLR) 8.8/10 Excellent! (939 reviews) Great staff. Helpful. Clean Reviewed on Feb 13, 2026 Don't see what you're looking for? See all available trips from Columbus to Istia d'Ombrone [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-28/2026-04-04/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=GRS&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_6361369) ### Discover the most popular places to visit in Istia d'Ombrone #### Port of Marina di Grosseto Explore the waterfront in Marina di Grosseto with a trip to Port of Marina di Grosseto. Discover the area's countryside and waterfalls. [](https://expedia.com/Port-Of-Marina-Di-Grosseto-Grosseto.d553248621532497633.Vacation-Attraction) #### Hospital of Mercy - Emergency Room Though Hospital of Mercy - Emergency Room might be what brings you to town, perhaps you'll have a chance to explore more of Grosseto while you are here. [](https://expedia.com/Hospital-Of-Mercy-Emergency-Room-Grosseto.d553248635975711400.Vacation-Attraction) #### Grosseto Cathedral Grosseto Cathedral is just one of the places to see in Grosseto, so why not enjoy the other things to explore during your travels? Discover the area's waterfalls and monuments. [](https://expedia.com/Grosseto-Cathedral-Grosseto.d6102970.Vacation-Attraction) ### What to do in Istia d'Ombrone ![La Maliosa Farm Experience & Wine Tasting](https://mediaim.expedia.com/localexpert/44638298/2d7ee171-839d-48ec-b768-c660cead2473.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### La Maliosa Farm Experience & Wine Tasting $53 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/la-maliosa-farm-experience-wine-tasting.a44638298.activity-details) ![From Fiumicino Airport: 1-Way Bus Transfer to Paganico](https://mediaim.expedia.com/localexpert/48206464/247937e6-d734-4208-917c-ad2494f7279f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### From Fiumicino Airport: 1-Way Bus Transfer to Paganico $11 per adult [](https://expedia.com/things-to-do/from-fiumicino-airport-1-way-bus-transfer-to-paganico.a48206464.activity-details) ![In the Footstep of the Etruscans: Hike & Wine Tasting](https://mediaim.expedia.com/localexpert/47811075/9b29f97e-8b7f-40d8-9519-dd33720676e7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### In the Footstep of the Etruscans: Hike & Wine Tasting $259 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/in-the-footstep-of-the-etruscans-hike-wine-tasting.a47811075.activity-details) [See all activities in Istia d'Ombrone](https://expedia.com/things-to-do/search?rid=6361369) ## Istia d'Ombrone Hotel Deals ![Terme di Saturnia Natural Spa & Golf Resort - The Leading Hotels of the World](https://images.trvl-media.com/lodging/7000000/6490000/6488700/6488645/430d6cf9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Terme di Saturnia Natural Spa & Golf Resort - The Leading Hotels of the World Via della Follonata Manciano GR Fully refundableReserve now, pay when you stay $451 nightly $499 total Mar 4 - Mar 5 Total with taxes and fees 9.4/10 Exceptional! (462 reviews) The window in the room was not big enough, the staff was not very nice. Although the things above spa aria , the food and the outdoor space was satisfying Reviewed on Jan 4, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&selected=6488645&PinnedHotelID=6488645&HadPinnedHotel=true®ionId=6361369) ![Grand Hotel Bastiani](https://images.trvl-media.com/lodging/2000000/1280000/1277600/1277581/e5c725af_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Grand Hotel Bastiani Piazza Gioberti 64 Grosseto GR Fully refundableReserve now, pay when you stay $91 nightly $100 total Mar 2 - Mar 3 Total with taxes and fees 8.6/10 Excellent! (227 reviews) The room was spotless, the bed was comfortable and really liked the old school fittings in the bathroom. During our stay the staff were happy, friendly and very helpful. Reviewed on Feb 13, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F2%2F2026&endDate=3%2F3%2F2026&selected=1277581&PinnedHotelID=1277581&HadPinnedHotel=true®ionId=6361369) ![Hotel Airone](https://images.trvl-media.com/lodging/23000000/22490000/22481500/22481472/c64e3088_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Airone Via Senese, 35 Grosseto GR Fully refundableReserve now, pay when you stay $116 nightly $127 total Mar 1 - Mar 2 Total with taxes and fees 8.4/10 Very Good! (110 reviews) Clean rooms, friendly staff Reviewed on Oct 15, 2025 [](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=22481472&PinnedHotelID=22481472&HadPinnedHotel=true®ionId=6361369) [See all 1,865 properties in Istia d'Ombrone](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F1%2F2026&endDate=3%2F2%2F2026®ionId=6361369) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Istia d'Ombrone Vacation Packages ## Istia dOmbrone Essential Information | Language | Italian | | --------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Euros | | Local Welcome | Ciao | | Local Goodbye | Ciao | | Max Temp Winter | 55ºF | | Max Temp Summer | 80ºF | | Top Sights | [Natural Park of Maremma](https://www.expedia.com/Natural-Park-Of-Maremma-Grosseto.d6183156.Vacation-Attraction), [Cantina Sociale i Vini di Maremma](https://www.expedia.com/Cantina-Sociale-I-Vini-Di-Maremma-Grosseto.d553248621532497644.Vacation-Attraction) and [Azienda Agricola Celestina Fe](https://www.expedia.com/Azienda-Agricola-Celestina-Fe-Grosseto.d553248621532497648.Vacation-Attraction) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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