Find hotels in Mayo, FL from $55

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Check Mayo hotel prices

Tonight
May 20 - May 21
Tomorrow night
May 21 - May 22
This weekend
May 24 - May 26
Next weekend
May 31 - Jun 2

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Compare 495 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Property grounds
Country Estate Villa, Private Pool, 30min to Beach
10.0 out of 10, Exceptional, (2)
"If you’re looking to book a house for a trip to Perry or anywhere remotely close, this place is it. Great location, beautiful and VERY spacious! Super clean! Great pool! Well stocked kitchen! We had a blast fishing during the days and enjoying the wide amenities of the property in the evenings! Property manager is an absolute gem of a woman who checked on us throughout our stay and even brought us wood and starter for the fire pit they have outside. She is amazing! Stop your search and go ahead...
The price is $371
$753 total
includes taxes & fees
Jun 6 - Jun 7
Country Estate Villa, Private Pool, 30min to Beach
Property grounds
The River House
10.0 out of 10, Exceptional, (47)
"The Suwannee River has become our favorite destination for vacation. Although it had rained and flooded the springs during our visit we had a wonderful time. We caught 3 big catfish! We played basketball, & darts. The porch is amazing for sitting and drinking coffee and watching the river. We will definitely be back. The owners were awesome with getting us to the house as the GPS took us down the wrong road. Everything was clean and I sure appreciated the creamers provided as I forgot to buy...
The River House
Property grounds
250 acres Wilderness cabin on the Suwannee River
10.0 out of 10, Exceptional, (6)
"The property is amazing! Very well maintained, quiet, and peaceful. Loved the cabin and it’s decor. Very cozy and had the comforts of home. Our family that lives in Mayo, FL (near the cabin) has atvs so we were able to take advantage of the trails across the street from the cabin. The river was flowing super fast due to the weather so we weren’t able to fish or kayak but we still had a blast! We would definitely recommend this place and cannot wait to come back!!"
250 acres Wilderness cabin on the Suwannee River
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Beach
The Best memories are made on the Suwannee River
10.0 out of 10, Exceptional, (50)
"The little house on the river is very homey and cozy. The river view from the windows is amazing. So many stars to gaze at during the night and the peaceful flow of the river washes away all your worries. Great place for a couples getaway or a family gathering. Dorothy the host was amazing. Very attentive and kind. I would certainly stay again. The house is very close to springs and very country. Just what I was looking for. Thanks again for opening your home to a lovely vacation."
The price is $145
$297 total
includes taxes & fees
May 21 - May 22
The Best memories are made on the Suwannee River
Property grounds
The Sea Shed
9.8 out of 10, Exceptional, (7)
"Very nice and clean, would definitely recommend staying here!"
The price is $89
$176 total
includes taxes & fees
May 31 - Jun 1
The Sea Shed
Exterior
Suwannee river hides
9.8 out of 10, Exceptional, (46)
"Location was the primary attraction. We were in town for a family holiday within close proximity to the rental. The tiny house has everything you need to feel at home. We slept well. Enjoyed coffee on the deck. Watched the river slip by."
Suwannee river hides
Property grounds
15 ACRE RIVER FRONT CABIN HOUSE ON THE SUWANNEE, WITH SPRING WALKING DISTANCE
9.8 out of 10, Exceptional, (33)
"gorgeous"
15 ACRE RIVER FRONT CABIN HOUSE ON THE SUWANNEE, WITH SPRING WALKING DISTANCE
Property grounds
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
9.6 out of 10, Exceptional, (50)
"We have stayed at margaritaville once before we really enjoy the property and cabin! Unfortunately the River was flooded and the kayaks weren’t in the best condition for such an intense River. Over all we had a blast. The second floor was perfect for the teenage boys to have some privacy and fun. We had everything we need to have awesome family dinners and our pets we’re safe and in heaven!"
The price is $199
$434 total
includes taxes & fees
May 21 - May 22
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
Exterior
Suwannee River Seclusion
9.6 out of 10, Exceptional, (15)
"When enjoyed our stay. Overall, the house was neat and clean and included several extras. We had friends a couple doors down with a vacation home, so they helped us maneuver around town. We were disappointed that there was no TV in the master bedroom as per the description. The property manager explained the last guests broke it. No compensation was offered. We would stay again."
Suwannee River Seclusion
BBQ/picnic area
Cindys Motel
2.5 star property
9.0 out of 10, Wonderful, (89)
"Nice owner who is very attentive and helpful. It’s sort of what you would expect for a small motel in a small town, reasonable price with no frills."
The price is $98
$104 total
includes taxes & fees
May 23 - May 24
Cindys Motel
LCD TV
Royal Inn Motel
2.0 star property
8.6 out of 10, Excellent, (782)
"Clean, worth it!! Very happy..."
The price is $79
$88 total
includes taxes & fees
May 21 - May 22
Royal Inn Motel
Suite, 2 Bedrooms, Jetted Tub (1 King Bed) | In-room safe, desk, laptop workspace, blackout drapes
Holiday Inn Express Hotel & Suites PERRY, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (569)
"Rooms were very nice and clean! Breakfast good also"
The price is $134
$150 total
includes taxes & fees
May 25 - May 26
Holiday Inn Express Hotel & Suites PERRY, an IHG Hotel
Exterior
Hampton Inn Perry
2.5 star property
8.6 out of 10, Excellent, (590)
"Clean place"
The price is $118
$132 total
includes taxes & fees
Jun 6 - Jun 7
Hampton Inn Perry
Room, 2 Double Beds, Non Smoking | Individually decorated, individually furnished, bed sheets
Skylark Motel
2.5 star property
5.8 out of 10, (40)
"I booked a room online and paid with a card at that time. There were instructions as well as an email sent to me which include check in times/office hours until 10 pm. We got there about 20 minutes before 10 pm to find the office locked. On the door, a piece of paper where the office hours had been altered by scribbling out "10pm" with a sharpie and replacing it with "9pm.""
Skylark Motel
Individually furnished, soundproofing, iron/ironing board, free WiFi
Regency Inn
2.5 star property
5.2 out of 10, (208)
"The staff was very helpful "
The price is $55
$62 total
includes taxes & fees
Jun 2 - Jun 3
Regency Inn
Property grounds
Newish luxury RV on private 8 acres on SUWANNEE
Newish luxury RV on private 8 acres on SUWANNEE
Don't see what you're looking for?
See all available properties in Mayo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More cheap stays in Mayo

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283

6819 Us Highway 129, Live Oak, FL
The price is $91 per night from Jun 16 to Jun 17
$91
$100 total
includes taxes & fees
Jun 16 - Jun 17
6.8/10 (404 reviews)

Stay near popular Mayo attractions

Image for Lafayette Blue Springs State Park

Lafayette Blue Springs State Park

3.5/5(4 reviews)

Explore the great outdoors at Lafayette Blue Springs State Park, a lovely green space in Mayo.

See properties
Lafayette Blue Springs State Park

Mayo Travel Info

Number of reviews
2,920
Accommodation
495 hotels
Highest price
$371
Lowest price
$55
Why to go
Lafayette Blue Springs State Park

Frequently asked questions

Where is the best place to stay in Mayo?

Based on Expedia's traveler preferences, Cindys Motel is a top place to stay in Mayo. Two other choices for your trip to the area are Holiday Inn Express Hotel & Suites LIVE OAK, an IHG Hotel and Best Western Plus Madison. See all available top hotels, or vacation rentals in Mayo.

What are some of the best vacation home rentals in Mayo?

Dekle Beach Darling - Beautiful Sunsets and Great Fishing : Visitors like this Mayo vacation home rental. It offers a balcony, a spa tub, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Mayo.

If I need to cancel my hotel reservation in Mayo, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Mayo.

Where can I learn more about changing or cancelling my trip to Mayo?

For more information about picking new dates or cancelling your trip to Mayo, click here.

What's the best pet-friendly hotel in Mayo?

Cindys Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Mayo.

Where is the best hotel to stay near Lafayette Blue Springs State Park?

Cindys Motel is one of the top choices for your stay based on our traveler data, and this property offers free parking and free WiFi. You'll find it 5.7 mi (9.2 km) from Lafayette Blue Springs State Park. Other good choices around the area include PEACOCK SPRINGS CAMPING!! 1 GENERATOR HOOKUP. 1 ELECTRIC HOOKUP! and Your Safari on the Suwannee River.

What are some accommodations with pools in Mayo?

Holiday Inn Express Hotel & Suites LIVE OAK, an IHG Hotel: Provides buffet, an outdoor pool, and free self parking. Best Western Plus Madison and Hampton Inn Perry are two additional hotels that offer an onsite pool. View all hotels with pools in Mayo.

What is the best accommodation for staying close to Jacksonville International Airport (JAX)?

DoubleTree by Hilton Hotel Jacksonville Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Jacksonville Intl. Airport. Other choices within close proximity to the airport include Microtel Inn & Suites by Wyndham Jacksonville Airport and Hampton Inn Suites Jacksonville Airport.

How is it to stay in Mayo?

Visitors can enjoy all that Mayo has to offer including its parks. In Mayo, there are 12 hotels and other accommodations to choose from. Find out more about Mayo.

What are the top places to visit in Mayo?

Natural beauty is on display at Lafayette Blue Springs State Park, Suwannee River, and Veteran's Memorial Park of Mayo. A couple of additional sights to add to your agenda are Lafayette County Library and Perry Spring. Check out what more to see and do in Expedia's Mayo guide.

What's the seasonal weather like in Mayo?

The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for Mayo is 51 inches.

Recent reviews of Mayo hotels
Expedia verified reviews

Royal Inn Motel

Royal Inn Motel

5/5 Excellent
"Clean, worth it!! Very happy..."
A verified traveler stayed at Royal Inn Motel
Posted 6 days ago
Royal Inn Motel