Title: Visit Mayo: 2026 Travel Guide for Mayo, Florida | Expedia.com

[Hotels in Mayo](https://expedia.com/Mayo-Hotels.d6286979.Travel-Guide-Hotels)[Vacation Rentals in Mayo](https://expedia.com/Mayo-Vacation-Rentals.d6286979.Travel-Guide-VacationRentals)[Flights to Mayo](https://expedia.com/Cheap-Flights-To-Mayo.d6286979.Travel-Guide-Flights)[Car Rentals in Mayo](https://expedia.com/Car-Rentals-In-Mayo.d6286979.Car-Rental-Guide)[Mayo Vacation Packages](https://expedia.com/Mayo.d6286979.Destination-Travel-Guides)

# Mayo, FL

## Travel Guide

![The view of Manatee Springs and Suwannee River. Manatee Springs State Park is in Chiefland, Florida](https://images.trvl-media.com/place/6286979/5dd23773-1205-4776-836a-48316c56dcec.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![The view of Manatee Springs and Suwannee River. Manatee Springs State Park is in Chiefland, Florida](https://images.trvl-media.com/place/6286979/5dd23773-1205-4776-836a-48316c56dcec.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![The view of Manatee Springs and Suwannee River. Manatee Springs State Park is in Chiefland, Florida](https://images.trvl-media.com/place/6286979/e8b753d1-d95a-44dd-a5fb-c464b2e827a6.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![The view of Manatee Springs and Suwannee River. Manatee Springs State Park is in Chiefland, Florida](https://images.trvl-media.com/place/6286979/82b53b85-7423-4a41-9262-e332ff7b3262.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

## Visit Mayo

Things to do

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_6286979)

- Mayo Hotel Deals
- Vacation Rentals in Mayo

![Suwannee River Rendezvous](https://images.trvl-media.com/lodging/112000000/111770000/111760600/111760596/994169e1_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Suwannee River Rendezvous

828 NE Primrose Rd Mayo FL

$43 nightly

$46 total

Mar 12 - Mar 13

Total with taxes and fees

Stay at this resort in Mayo. Enjoy free WiFi, free parking, and 3 outdoor pools. Popular attractions Wes Skiles Peacock Springs State Park and Telford Spring ...

8.8/10 Excellent! (24 reviews)

Friendly staff, nice views, good food at the cook shack, pool and hot tub in the 21+ section were great!

Reviewed on Feb 16, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F12%2F2026&endDate=3%2F13%2F2026&selected=111760596&PinnedHotelID=111760596&HadPinnedHotel=true&regionId=6286979)

![Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,](https://images.trvl-media.com/lodging/118000000/117030000/117028300/117028207/b939a190_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

 Mayo FL

$64 nightly

$67 total

Mar 12 - Mar 13

Total with taxes and fees

Stay at this cabin in Mayo. Enjoy free WiFi, a garden, and patios. Popular attraction Allen Mill Pond Spring is located nearby.

9.8/10 Exceptional! (6 reviews)

Nice and pet friendly

Reviewed on Mar 7, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F12%2F2026&endDate=3%2F13%2F2026&selected=117028207&PinnedHotelID=117028207&HadPinnedHotel=true&regionId=6286979)

![Cindys Motel](https://images.trvl-media.com/lodging/40000000/39450000/39448900/39448879/f9b4a9c4_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Cindys Motel

487 W Main St Mayo FL

$83 nightly

$89 total

Apr 5 - Apr 6

Total with taxes and fees

Stay at this motel in Mayo. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions Veteran's ...

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=39448879&PinnedHotelID=39448879&HadPinnedHotel=true&regionId=6286979)

[See all 475 properties in Mayo](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F12%2F2026&endDate=3%2F13%2F2026&regionId=6286979)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,](https://images.trvl-media.com/lodging/118000000/117030000/117028300/117028207/b939a190_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

 Mayo FL

Stay at this cabin in Mayo. Enjoy free WiFi, a garden, and patios. Popular attraction Allen Mill Pond Spring is located nearby.

9.8/10 Exceptional! (6 reviews)

Nice and pet friendly

Reviewed on Mar 7, 2026

[](https://expedia.com/Mayo-Hotels-Friendlys-River-Retreat-1-Cozy-Couples-Cabin-In-Awesome-Mayo-With-WiFi.h117028207.Hotel-Information)

![Suwannee River Retreat with Private Dock, Free Kayaks, and Fire pit](https://images.trvl-media.com/lodging/61000000/60340000/60338600/60338546/9fae31c0_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Suwannee River Retreat with Private Dock, Free Kayaks, and Fire pit

 Mayo FL

Stay at this vacation home in Mayo. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Wes Skiles Peacock Springs State Park and Telford ...

10/10 Exceptional! (73 reviews)

Everything was great and accurate. We loved it. If I had younger children I would be concerned about the river but if you watch the kids it is all cool. Lots of wildlife and close to all the springs. We would stay again. Very quite and secluded.

Reviewed on Nov 3, 2025

[](https://expedia.com/Mayo-Hotels-The-River-House.h60338546.Hotel-Information)

![Friendlys River Retreat private 
Rustic Camping Cabin sleeps 4+with tent camping](https://images.trvl-media.com/lodging/116000000/115960000/115956900/115956827/a05c6668_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

 Mayo FL

Stay at this cabin in Mayo. Enjoy a garden, patios, and air conditioning. Popular attraction Allen Mill Pond Spring is located nearby.

9.8/10 Exceptional! (9 reviews)

Extremely pet friendly & the cabin was warm and cozy even on cold nights. Be prepared for a short walk to the shared restroom to use the toilet and shower.

Reviewed on Jan 2, 2026

[](https://expedia.com/Mayo-Hotels-Friendlys-River-Retreat-Private-Rustic-Camping-Cabin-Sleeps-4with-Tent-Camping.h115956827.Hotel-Information)

[See all properties in Mayo](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&regionId=6286979&sort=VACATION_RENTAL)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Check Mayo hotel availability

[Tonight

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6286979&startDate=2026-03-11&endDate=2026-03-12)[Mar 11 - Mar 12](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6286979&startDate=2026-03-11&endDate=2026-03-12)

[Tomorrow night

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6286979&startDate=2026-03-12&endDate=2026-03-13)[Mar 12 - Mar 13](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6286979&startDate=2026-03-12&endDate=2026-03-13)

[This weekend

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6286979&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026)[Mar 13 - Mar 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6286979&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026)

[Next weekend

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6286979&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)[Mar 20 - Mar 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=6286979&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)

### Popular places to visit

#### Lafayette Blue Springs State Park

3.5/5(4 reviews)

You can take time to visit Lafayette Blue Springs State Park during your travels to Mayo. While you're in the area, wander around the parks. 

[](https://expedia.com/Lafayette-Blue-Springs-State-Park-Mayo.d553248621532654049.Vacation-Attraction)

#### Perry Spring

Commune with nature and explore the great outdoors at Perry Spring during your travels in Mayo. While you're in the area, wander around the parks. 

[](https://expedia.com/Perry-Spring-Mayo.d874556687860871168.Vacation-Attraction)

#### Lafayette County Library

After visiting Lafayette County Library, make a plan to see the other sights and activities in Mayo. While you're in the area, wander around the parks. 

[](https://expedia.com/Lafayette-County-Library-Mayo.d874555788411269120.Vacation-Attraction)

## Cities near Mayo

![kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Live Oak

![Aerial panorama of St. Augustine, Florida. Founded in 1565 by Spanish explorers, it is the oldest continuously inhabited European-established settlement in what is now the contiguous United States.](https://images.trvl-media.com/place/3000441023/3e420597-9084-4b42-b318-4270f08bfce5.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Old Town

![Branford Spring (A.K.A. Ivey Spring) in Ivey Memorial Park, Branford, Florida](https://images.trvl-media.com/place/6188028/c2e52b5f-3ee1-46e5-87da-f05b9ed110f8.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Branford

![An amazing state Park 2 hours drive from Orlando. Swimming and snorkeling in this crystal clear water is allowed and i really recommend to do it! 🐟🐢](https://images.trvl-media.com/place/6286968/6ef14131-623c-497c-b3f3-edb4a56b8714.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### O Brien

## Explore a world of travel with Expedia

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- [Alton Hotels ](https://www.expedia.com/Alton-Hotels.d553248635975876473.Travel-Guide-Hotels)
- [Hotels near Lafayette Blue Springs State Park ](https://www.expedia.com/Lafayette-Blue-Springs-State-Park-Hotels.0-l553248621532654049-0.Travel-Guide-Filter-Hotels)
- [Hotels near Wes Skiles Peacock Springs State Park ](https://www.expedia.com/Wes-Skiles-Peacock-Springs-State-Park-Hotels.0-l553248621532654050-0.Travel-Guide-Filter-Hotels)
- [Hotels near Troy Spring State Park ](https://www.expedia.com/Troy-Spring-State-Park-Hotels.0-l6285999-0.Travel-Guide-Filter-Hotels)
- [Day Hotels ](https://www.expedia.com/Day-Hotels.d553248635975869176.Travel-Guide-Hotels)
- [Dowling Park Hotels ](https://www.expedia.com/Dowling-Park-Hotels.d97729.Travel-Guide-Hotels)
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- [Flights to Lafayette County ](https://www.expedia.com/Destinations-In-Lafayette-County.d553248635976430567.Flight-Destinations)
- [Flights to Dowling Park ](https://www.expedia.com/Cheap-Flights-To-Dowling-Park.d97729.Travel-Guide-Flights)
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- [Flights from Mcalpin ](https://www.expedia.com/lp/flights/3000345299/flights-from-mcalpin)
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- [Flights from Live Oak ](https://www.expedia.com/lp/flights/10072/flights-from-live-oak)

- [Wes Skiles Peacock Springs State Park ](https://www.expedia.com/Wes-Skiles-Peacock-Springs-State-Park-Live-Oak.d553248621532654050.Vacation-Attraction)
- [Visit Dowling Park ](https://www.expedia.com/Dowling-Park.dx97729)
- [Visit O Brien ](https://www.expedia.com/O-Brien.dx3000431472)
- [Dowling Park Vacations ](https://www.expedia.com/Dowling-Park.d97729.Destination-Travel-Guides)
- [Visit Mcalpin ](https://www.expedia.com/Mcalpin.dx3000345299)
- [Visit Branford ](https://www.expedia.com/Branford.dx6188028)
- [First Federal Sportsplex ](https://www.expedia.com/First-Federal-Sportsplex-Live-Oak.d6185397.Vacation-Attraction)
- [Visit Live Oak ](https://www.expedia.com/Live-Oak.dx10072)

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- [Car rentals near Dowling Park ](https://www.expedia.com/Car-Rentals-In-Dowling-Park.d97729.Car-Rental-Guide)
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- [Car rentals near Mcalpin ](https://www.expedia.com/Car-Rentals-In-Mcalpin.d3000345299.Car-Rental-Guide)
- [Car rentals near Branford ](https://www.expedia.com/Car-Rentals-In-Branford.d6188028.Car-Rental-Guide)
- [Car rentals near Athena ](https://www.expedia.com/Car-Rentals-In-Athena.d553248635975848836.Car-Rental-Guide)
- [Car rentals near Live Oak ](https://www.expedia.com/Car-Rentals-In-Live-Oak.d10072.Car-Rental-Guide)
- [Enterprise Rental Cars in Live Oak ](https://www.expedia.com/Enterprise-Car-Rentals-In-Live-Oak.d10072-c15.Car-Rental-Guide-Suppliers)
- [Budget Rental Cars in Live Oak ](https://www.expedia.com/Budget-Car-Rentals-In-Live-Oak.d10072-c39.Car-Rental-Guide-Suppliers)
- [Avis Rental Cars in Live Oak ](https://www.expedia.com/Avis-Car-Rentals-In-Live-Oak.d10072-c41.Car-Rental-Guide-Suppliers)
- [Van Car Rentals in Live Oak ](https://www.expedia.com/Van-Car-Rentals-In-Live-Oak.d10072-tVan.Car-Rental-Guide-Class)
- [Hertz Rental Cars in Live Oak ](https://www.expedia.com/Hertz-Car-Rentals-In-Live-Oak.d10072-c40.Car-Rental-Guide-Suppliers)

- [Dowling Park Vacation Rentals ](https://www.expedia.com/Dowling-Park-Vacation-Rentals.d97729.Travel-Guide-VacationRentals)
- [O Brien Vacation Rentals ](https://www.expedia.com/O-Brien-Vacation-Rentals.d3000431472.Travel-Guide-VacationRentals)
- [Mcalpin Vacation Rentals ](https://www.expedia.com/Mcalpin-Vacation-Rentals.d3000345299.Travel-Guide-VacationRentals)
- [Branford Vacation Rentals ](https://www.expedia.com/Branford-Vacation-Rentals.d6188028.Travel-Guide-VacationRentals)
- [Live Oak Vacation Rentals ](https://www.expedia.com/Live-Oak-Vacation-Rentals.d10072.Travel-Guide-VacationRentals)

- Cities near Mayo
- Places of interest

[Live Oak](https://expedia.com/Live-Oak.dx10072)[Dowling Park](https://expedia.com/Dowling-Park.dx97729)[Old Town](https://expedia.com/Old-Town.dx183110)[Branford](https://expedia.com/Branford.dx6188028)[O Brien](https://expedia.com/O-Brien.dx3000431472)

- [Ichetucknee Springs State Park ](https://expedia.com/Ichetucknee-Springs-State-Park-Florida.d6285986.Vacation-Attraction)
- [Madison Blue Springs State Park ](https://expedia.com/Madison-Blue-Springs-State-Park-Lee.d553248621561885532.Vacation-Attraction)
- [Suwannee River State Park ](https://expedia.com/Suwannee-River-State-Park-Florida.d6128386.Vacation-Attraction)
- [Santa Fe River ](https://expedia.com/Santa-Fe-River-Florida.d684510373599707136.Vacation-Attraction)
- [Sea Hag Marina ](https://expedia.com/Sea-Hag-Marina-Steinhatchee.d6184506.Vacation-Attraction)
- [Steinhatchee Falls ](https://expedia.com/Steinhatchee-Falls-Steinhatchee.d6184509.Vacation-Attraction)
- [Yogi Bear's Jellystone Park ](https://expedia.com/Yogi-Bears-Jellystone-Park-Madison.d553248621532654110.Vacation-Attraction)
- [Steinhatchee Public Boat Ramp ](https://expedia.com/Steinhatchee-Public-Boat-Ramp-Steinhatchee.d6184496.Vacation-Attraction)
- [Bob's River Place ](https://expedia.com/Bobs-River-Place-Old-Town.d553248633992473977.Vacation-Attraction)
- [One More Cast ](https://expedia.com/One-More-Cast-Perry.d553248621561885554.Vacation-Attraction)
- [Wes Skiles Peacock Springs State Park ](https://expedia.com/Wes-Skiles-Peacock-Springs-State-Park-Live-Oak.d553248621532654050.Vacation-Attraction)
- [Perry Train Depot ](https://expedia.com/Perry-Train-Depot-Perry.d6184295.Vacation-Attraction)
- [Fort Steinhatchee Pier ](https://expedia.com/Fort-Steinhatchee-Pier-Steinhatchee.d553248635975635233.Vacation-Attraction)
- [Lake Frances Recreation Area ](https://expedia.com/Lake-Frances-Recreation-Area-Madison.d6183971.Vacation-Attraction)
- [Gibson Park ](https://expedia.com/Gibson-Park-Jasper.d6183615.Vacation-Attraction)
- [Doctors Memorial Hospital ](https://expedia.com/Doctors-Memorial-Hospital-Perry.d6184280.Vacation-Attraction)
- [Suwannee County Historical Museum ](https://expedia.com/Suwannee-County-Historical-Museum-Live-Oak.d6185403.Vacation-Attraction)
- [Hagen Cove ](https://expedia.com/Hagen-Cove-Florida.d6184500.Vacation-Attraction)

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