Title: Mayo Lake Tours - Book Now | Expedia.com [Mayo Lake Hotels](https://expedia.com/Mayo-Lake-Hotels.0-l553248635976197372-0.Travel-Guide-Filter-Hotels)[Flights to Roxboro](https://expedia.com/Cheap-Flights-To-Roxboro.d6441.Travel-Guide-Flights)[Car Rentals in Mayo Lake](https://expedia.com/Car-Rentals-In-Mayo-Lake.d553248635976197372.Car-Rental-Guide)[Roxboro Vacation Packages](https://expedia.com/Roxboro.d6441.Destination-Travel-Guides) # Mayo Lake Tours ## Visit Mayo Lake Activities [Roxboro Travel Guide](https://expedia.com/Roxboro.dx6441) --- --- ## Plan a trip to see Mayo Lake Price found within the past 48 hours. Click for updated prices. ![Comfort Inn University Durham - Chapel Hill](https://images.trvl-media.com/lodging/1000000/10000/5000/4989/3e593195_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Comfort Inn University Durham - Chapel Hill $328 per person Jun 5 - Jun 8 found 14 hours ago Roundtrip flight included Boston (BOS) to Raleigh (RDU) 7.8/10 Good! (995 reviews) Bathrooms really need updated. Pain peeling off the bathtub and the handle was not secure Reviewed on Mar 6, 2026 ![Sheraton Raleigh Hotel](https://images.trvl-media.com/lodging/1000000/10000/8900/8897/b7c72cba_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Sheraton Raleigh Hotel Downtown Raleigh Save 100% on your flight $500 per person Jun 5 - Jun 8 found 14 hours ago Roundtrip flight included Boston (BOS) to Raleigh (RDU) 8.2/10 Very Good! (1,004 reviews) The staff was very kind at check in. We had a wonderful time. We came in for a concert. The parking garage was difficult to navigate with pricing. But this is not affiliate with the hotel. We highly recommend that you stay here. Reviewed on Mar 18, 2026 ![University Inn Durham next to Duke University Medical Center](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/80e8b722_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### University Inn Durham next to Duke University Medical Center $787 per person May 7 - May 10 found 1 day ago Roundtrip non-stop flight included Boston (BOS) to Raleigh (RDU) 9/10 Wonderful! (1,012 reviews) Solid & affordable choice, close to the hospital and clinics. Reviewed on Mar 10, 2026 ### Popular places to visit ![Ben Lomond is a historic site in Manassas Virginia, which was built by Benjamin Tasker Chinn and used as a former plantation and then hospital during](https://images.trvl-media.com/place/6304507/c4e30b79-0c8f-4fda-ab57-5680df6b197c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Person County Museum You can spend an afternoon exploring the galleries in Person County Museum during your trip to Roxboro. Wander the lakeside in this family-friendly area. [](https://expedia.com/Person-County-Museum-Roxboro.d6304507.Vacation-Attraction) ![Old South United Methodist Church aerial view panorama at sunset in historic town center, Reading, Massachusetts, MA, USA.](https://images.trvl-media.com/place/909171578584346624/0b765c34-47fc-4a17-8961-a94cd6e15610.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### South Boston Town Hall South Boston Town Hall is just one of the places to see in South Boston, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can enjoy the restaurants. [](https://expedia.com/South-Boston-Town-Hall-South-Boston.d909171578584346624.Vacation-Attraction) #### Mayo Park Explore the great outdoors at Mayo Park, a lovely green space in Roxboro. Stroll along the lakeside or visit the shops in this family-friendly area. [](https://expedia.com/Mayo-Park-Roxboro.d907564612755742720.Vacation-Attraction) #### Piedmont Community College Explore the campus of Piedmont Community College as part of your travels around Roxboro. Stroll along the lakeside or visit the shops in this family-friendly area. [](https://expedia.com/Piedmont-Community-College-Roxboro.d907568931529908224.Vacation-Attraction) #### Longhurst Park After visiting Longhurst Park, make a plan to see the other sights and activities in Roxboro. Stroll along the lakeside or visit the shops in this family-friendly area. [](https://expedia.com/Longhurst-Park-Roxboro.d907564725056114688.Vacation-Attraction) #### Person Memorial Hospital Though Person Memorial Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Roxboro while you are here. [](https://expedia.com/Person-Memorial-Hospital-Roxboro.d907569995144585216.Vacation-Attraction) --- ## Best Lodging Options Near Mayo Lake ## Check availability on hotels close to Mayo Lake [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248635976197372&startDate=2026-03-19&endDate=2026-03-20)[Mar 19 - Mar 20](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248635976197372&startDate=2026-03-19&endDate=2026-03-20) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248635976197372&startDate=2026-03-20&endDate=2026-03-21)[Mar 20 - Mar 21](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248635976197372&startDate=2026-03-20&endDate=2026-03-21) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248635976197372&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026)[Mar 20 - Mar 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248635976197372&startDate=3%2F20%2F2026&endDate=3%2F22%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248635976197372&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248635976197372&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) ![Budget Inn Roxboro](https://images.trvl-media.com/lodging/12000000/11720000/11713000/11712961/c3cfb2d7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Budget Inn Roxboro 1033 N Madison Blvd Roxboro NC [](https://expedia.com/Roxboro-Hotels-Budget-Inn-Roxboro.h11712961.Hotel-Information) ![Fairfield Inn & Suites South Boston](https://images.trvl-media.com/lodging/3000000/2830000/2827400/2827362/6fa5e52d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fairfield Inn & Suites South Boston 1120 Bill Tuck Hwy South Boston VA [](https://expedia.com/Danville-Hotels-Fairfield-Inn-Suites-South-Boston.h2827362.Hotel-Information) ![Super 8 by Wyndham South Boston VA](https://images.trvl-media.com/lodging/1000000/40000/40000/39984/d6f96c55_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Super 8 by Wyndham South Boston VA 1040 Bill Tuck Hwy South Boston VA [](https://expedia.com/Danville-Hotels-Super-8-By-Wyndham-South-Boston-VA.h39984.Hotel-Information) ![Clarion Pointe South Boston - Danville East](https://images.trvl-media.com/lodging/1000000/70000/60800/60769/21d537f1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Clarion Pointe South Boston - Danville East 1074 Bill Tuck Hwy South Boston VA [](https://expedia.com/Danville-Hotels-Clarion-Pointe-South-Boston-Danville-East.h60769.Hotel-Information) ![Americas Best Value Inn & Suites South Boston](https://images.trvl-media.com/lodging/1000000/20000/10400/10336/7587f6ce_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Americas Best Value Inn & Suites South Boston 2050 Philpott Rd South Boston VA [](https://expedia.com/Danville-Hotels-Americas-Best-Value-Inn-Suites-South-Boston.h10336.Hotel-Information) ![Hampton Inn Roxboro](https://images.trvl-media.com/lodging/1000000/160000/151400/151325/9c7dbd5a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Roxboro 920 Durham Rd Roxboro NC [](https://expedia.com/Roxboro-Hotels-Hampton-Inn-Roxboro.h151325.Hotel-Information) ![The Berry Hill Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/910000/907700/907687/53f7bca8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Berry Hill Resort & Conference Center 3105 River Road South Boston VA [](https://expedia.com/Danville-Hotels-The-Berry-Hill-Resort-Conference-Center.h907687.Hotel-Information) ![Quality Inn South Boston - Danville East](https://images.trvl-media.com/lodging/1000000/20000/12700/12631/cfd50284_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Quality Inn South Boston - Danville East 2001 Seymour Drive South Boston VA [](https://expedia.com/Danville-Hotels-Quality-Inn-South-Boston-Danville-East.h12631.Hotel-Information) ![Lakefront, Kayaks, SUPs, Hot Tub & Boat Options](https://images.trvl-media.com/lodging/34000000/33710000/33704000/33703912/8fcc8364_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Lakefront, Kayaks, SUPs, Hot Tub & Boat Options Leasburg NC [](https://expedia.com/Leasburg-Hotels-Lakefront.h33703912.Hotel-Information) [See all 813 properties in Mayo Lake](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=553248635976197372) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.