Medical Center Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Medical Center Vacation
Your next big adventure is just around the corner with a vacation package to Medical Center. Entertainment, relaxation and good times — you're bound to find it in this neighborhood. When it's time to take in the sights, you'll find loads of top attractions nearby including Creighton University, University of Nebraska-Omaha and CHI Health Center Omaha. Tick off one, two or all during your trip to Medical Center. Expedia will help you turn your dream Medical Center vacation into reality, whatever your travel plans or budget.
Price found within the past 48 hours. Click for updated prices.
- Hampton Inn Omaha Midtown-Aksarben Area
Jul 25 - Jul 28Hampton Inn Omaha Midtown-Aksarben Area + Flight
South Central Omaha3 nights9.2/10 - Wonderful (1,003 reviews)"Room clean and stocked well. Pool small and full of kids. Beds not very comfy. Pillows way too soft and not very supportive. If we are in the area again would probably try somewhere else. There is a great Italian restaurant down the road that I would definitely go to again."Reviewed May 24, 2026Roundtrip • Austin (AUS) - Omaha (OMA)AUS - OMA • Nonstop OMA - AUS • Nonstop$568$493found 1 day agoper traveler - Hilton Omaha
Jul 8 - Jul 11Hilton Omaha + Flight
Downtown Omaha3 nights8.8/10 - Excellent (1,003 reviews)"Help desk was not very friendly"Reviewed May 23, 2026Roundtrip • Chicago (MDW) - Omaha (OMA)MDW - OMA • Nonstop OMA - RFD • Nonstop$769$614found 22 hours agoper traveler - Home2 Suites by Hilton Omaha I-80 at 72nd Street, NE
Jul 25 - Jul 28Home2 Suites by Hilton Omaha I-80 at 72nd Street, NE + Flight
South Central Omaha3 nights9.4/10 - Exceptional (302 reviews)"Great place with great service and amenities!"Reviewed May 10, 2026Roundtrip • Austin (AUS) - Omaha (OMA)AUS - OMA • Nonstop OMA - AUS • Nonstop$575$493found 1 day agoper traveler - Magnolia Hotel Omaha
Jul 25 - Jul 28Magnolia Hotel Omaha + Flight
Downtown Omaha3 nights9.0/10 - Wonderful (1,928 reviews)"The room was OK and had comfortable beds. I was very disappointed in the bathroom as it was small and not well cleaned. The grout and edges of the of the floor, around the toilet and baseboard had visible grime and stains, not cleaned well at all. The vanity/sink chrome legs were dirty and rusted. I would not want to be barefoot in there, yuk. The vending machine prices were unreasonably high at $5.50 for a Dasani water and $5.00+ for a regular Hershey bar. There was no ice machine on my floor,..."Reviewed May 24, 2026Roundtrip • Austin (AUS) - Omaha (OMA)AUS - OMA • Nonstop OMA - AUS • Nonstop$602$519found 1 day agoper traveler - Hotel Deco
Jul 25 - Jul 28Hotel Deco + Flight
Downtown Omaha3 nights8.8/10 - Excellent (1,196 reviews)"We had to change rooms 3 times as what we booked( a king suite) and what we got was different. They put us into the 3rd room, with similar qualities and the big bathtub didn’t work. Wanted to move us again, but had already unpacked for our 3 night stay. I understand it’s under new management, but we had to ask for robes, ice machine unacceptable, and it was a waste of our time and money! Don’t open, if you’re not dotting all the eyes and crossing the ts! Expedia has some responsibility here as..."Reviewed May 25, 2026Roundtrip • Austin (AUS) - Omaha (OMA)AUS - OMA • Nonstop OMA - AUS • Nonstop$614$531found 1 day agoper traveler
Where to stay in Medical Center
Find the best Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center
Downtown Omaha
3 out of top 10 points of interest in this area
4/5(1,490 area reviews)
Explore the historic core of Omaha, where you'll find the Old Market Historic District, offering boutique shops, dining, and cultural activities. Don't miss the Orpheum Theater and Omaha Children's Museum nearby.
Medical Center Hotel Deals
Hampton Inn by Hilton Omaha UN Medical Center Area
4409 Douglas Omaha NE
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $123 total per night from May 28 to May 29
$123 total
May 28 - May 29
Total with taxes and fees
8.8/10 Excellent! (145 reviews)
"Comfortable stay!"
Reviewed on May 25, 2026
Home2 Suites by Hilton Omaha UN Medical Ctr Area
4440 DOUGLAS STREET Omaha NE
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from May 28 to May 29
$140 total
May 28 - May 29
Total with taxes and fees
8.8/10 Excellent! (533 reviews)
"Everything was good but our shower head was very week and the breakfast was ok"
Reviewed on May 24, 2026
Days Inn by Wyndham Omaha NE
11610 W Dodge Rd Omaha NE
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $71 total per night from Jun 4 to Jun 5
$71 total
Jun 4 - Jun 5
Total with taxes and fees
8.2/10 Very Good! (230 reviews)
"It was good, the photos online are a little misleading, but the property was very clean and the staff were very nice and friendly. I could have gotten a nicer hotel for the price but overall it was good."
Reviewed on May 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Medical Center
Henry Doorly Zoo and Aquarium
Journey through the world’s biggest indoor desert, spot magnificent creatures in the aquarium and explore indoor rainforests and swamps in Nebraska’s premier zoo.
Lauritzen Gardens
Wander through the diverse woodland areas, admire the charming waterfall and inspect the model railway system in this botanical park.
Charles Schwab Field Omaha
Catch an event at Charles Schwab Field Omaha during your trip to Omaha. Attend a sporting event or simply visit the area's shops.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.