Medical Center Vacations from $509

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Your Medical Center Vacation

Your next big adventure is just around the corner with a vacation package to Medical Center. Entertainment, relaxation and good times — you're bound to find it in this neighborhood. When it's time to take in the sights, you'll find loads of top attractions nearby including Creighton University, University of Nebraska-Omaha and CHI Health Center Omaha. Tick off one, two or all during your trip to Medical Center. Expedia will help you turn your dream Medical Center vacation into reality, whatever your travel plans or budget.

The Latest Medical Center Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hampton Inn Omaha Midtown-Aksarben Area

Hampton Inn Omaha Midtown-Aksarben Area

2.5 out of 5
South Central Omaha
Price was $597, price is now $509 per person
$509
per person
Jul 9 - Jul 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Omaha (OMA)
9.2/10 Wonderful! (1,000 reviews)
Greeted at front desk as I walked in for check in. Staff are friendly and helpful and the lobby is a great spot for getting together with a small group in the evening to catch up. Breakfast options provided were typically for continental breakfast. Overall a great location and would stay here again.

Reviewed on May 13, 2026

My Place Hotel - Council Bluffs/Omaha East, IA

My Place Hotel - Council Bluffs/Omaha East, IA

2.5 out of 5
Price was $741, price is now $618 per person
$618
per person
Jul 9 - Jul 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Omaha (OMA)
9.2/10 Wonderful! (1,371 reviews)
Everything was clean and ready. TV remote or tv function was poor

Reviewed on May 17, 2026

Hotel Deco

Hotel Deco

4.5 out of 5
Downtown Omaha
Price was $691, price is now $584 per person
$584
per person
Jul 9 - Jul 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Omaha (OMA)
8.8/10 Excellent! (1,181 reviews)
We had an amazing stay in this luxurious boutique hotel. The staff were very friendly and helpful. I would stay here again!

Reviewed on May 17, 2026

Hotel Indigo Omaha Downtown by IHG

Hotel Indigo Omaha Downtown by IHG

3.5 out of 5
Downtown Omaha
Price was $665, price is now $566 per person
$566
per person
Jul 9 - Jul 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Omaha (OMA)
9.4/10 Exceptional! (1,008 reviews)
Very clean. Unique decor. Awesome shampoo, conditioner, body wash and lotion. Love the big fluffy pillows. Could not reach guest services on phone outside of building. Used shuttle to go to zoo, tried 30 minutes to call for pickup but never reached guest services. Please have shuttle drivers provide us with their own number. Had to get an Uber. Very annoying after long hot day. Or hire remote workers to handle phone calls. Also ice machines broken on several floors, and only one microwave in building and it was on main floor. Please put microwave and upkeep ice machines on all floors. Staff that we did speak with were fire and helpful

Reviewed on May 16, 2026

The Peregrine Omaha Downtown, Curio Collection by Hilton

The Peregrine Omaha Downtown, Curio Collection by Hilton

4 out of 5
Downtown Omaha
Price was $601, price is now $515 per person
$515
per person
Jul 9 - Jul 12
found 5 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Omaha (OMA)
8.8/10 Excellent! (365 reviews)
We experienced some long delays for service at breakfast time

Reviewed on May 17, 2026

Where to stay in Medical Center

Find the best Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center
Downtown Omaha

Downtown Omaha

2 out of top 10 points of interest in this area
4/5(1,490 area reviews)

Explore the historic core of Omaha, where you'll find the Old Market Historic District, offering boutique shops, dining, and cultural activities. Don't miss the Orpheum Theater and Omaha Children's Museum nearby.

Find hotels in Downtown Omaha

Medical Center Hotel Deals

Hampton Inn by Hilton Omaha UN Medical Center Area

Hampton Inn by Hilton Omaha UN Medical Center Area

2.5 out of 5
4409 Douglas Omaha NE
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from May 24 to May 25
$110 total
May 24 - May 25
Total with taxes and fees
8.8/10 Excellent! (139 reviews)
Fresh hotel

Reviewed on May 16, 2026

Hampton Inn by Hilton Omaha UN Medical Center Area
Home2 Suites by Hilton Omaha UN Medical Ctr Area

Home2 Suites by Hilton Omaha UN Medical Ctr Area

3 out of 5
4440 DOUGLAS STREET Omaha NE
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $132 total per night from May 28 to May 29
$132 total
May 28 - May 29
Total with taxes and fees
8.8/10 Excellent! (531 reviews)
This was a great hotel centrally located. Very clean

Reviewed on May 17, 2026

Home2 Suites by Hilton Omaha UN Medical Ctr Area
Days Inn by Wyndham Omaha NE

Days Inn by Wyndham Omaha NE

2 out of 5
11610 W Dodge Rd Omaha NE
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $72 total per night from May 24 to May 25
$72 total
May 24 - May 25
Total with taxes and fees
8.2/10 Very Good! (199 reviews)
Muy bueno

Reviewed on May 17, 2026

Days Inn by Wyndham Omaha NE
See all 1,052 properties in Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Medical Center

Henry Doorly Zoo and Aquarium

Henry Doorly Zoo and Aquarium

Journey through the world’s biggest indoor desert, spot magnificent creatures in the aquarium and explore indoor rainforests and swamps in Nebraska’s premier zoo.

Henry Doorly Zoo and Aquarium
Lauritzen Gardens

Lauritzen Gardens

Wander through the diverse woodland areas, admire the charming waterfall and inspect the model railway system in this botanical park.

Lauritzen Gardens
Heartland of America Park

Heartland of America Park

Gaze up at the stunning light and water show at the fountain and hold hands on a romantic stroll through this charming park.

Heartland of America Park
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.