Mesa de Otay Vacations from $592

Book a Hotel + Flight or Car together to unlock savings

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The Latest Mesa de Otay Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Posada San Antonio
Alma Liebre Viñedos del Valle
Casa Santacruz
Sarab Hotel
Villas La Morita Valle de Guadalupe

Where to stay in Mesa de Otay

Find the best Mesa de Otay areas and neighborhoods for the activities you enjoy most. Learn more about Mesa de Otay

Mesa de Otay Hotel Deals

Quartz Hotel & SPA

Quartz Hotel & SPA

4.5 out of 5
Paseo Centenario 4210, Zona Urbana Rio Tijuana BC
$169 nightly
The price is $191 total per night from Dec 24 to Dec 25
$191 total
Dec 24 - Dec 25
Total with taxes and fees
9/10 Wonderful! (1,306 reviews)
Clean room

Reviewed on Dec 15, 2025

Quartz Hotel & SPA
One Tijuana Otay

One Tijuana Otay

3 out of 5
Ave. Aeropuerto 1600, Lote 20 Tijuana BC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $96 total per night from Jan 1 to Jan 2
$96 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
8.6/10 Excellent! (1,319 reviews)
Nice service

Reviewed on Dec 18, 2025

One Tijuana Otay
Hotel Pueblo Amigo Plaza & Casino

Hotel Pueblo Amigo Plaza & Casino

3.5 out of 5
Via Oriente 9211 Tijuana BC
Fully refundable
$126 nightly
The price is $142 total per night from Jan 22 to Jan 23
$142 total
Jan 22 - Jan 23, 2026
Total with taxes and fees
9.4/10 Exceptional! (1,564 reviews)
Not appilcable

Reviewed on Dec 21, 2025

Hotel Pueblo Amigo Plaza & Casino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Mesa de Otay

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.