Mesi Vacations from $265

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Your Mesi Vacation

Lock in a Mesi vacation package and get set to experience this exciting city the stress-free way. Consider staying in the neighborhood of Myli, which is great for views and hiking. If your trip to Mesi includes a little sightseeing, check out renowned attractions like Rethymnon Town Hall, Rethymnon Lighthouse and Arkadi Monastery. Check out Expedia's wide range of travel options and begin planning your dream vacation to Mesi today.

The Latest Mesi vacation packages

Price found within the past 48 hours. Click for updated prices.
Atrion Hotel

Atrion Hotel

3 out of 5
Price was $524, price is now $265 per person
$265
per person
Nov 9 - Nov 15
found 18 hours ago
Roundtrip flight included
Athens (ATH) to Heraklion (HER)
8.8/10 Excellent! (825 reviews)
The room was tiny and there were small ants crawling around on the floor.

Reviewed on Aug 19, 2025

The Noverian Antama Organic Beach Resort Chania

The Noverian Antama Organic Beach Resort Chania

5 out of 5
Price was $962, price is now $436 per person
$436
per person
Oct 13 - Oct 17
found 1 day ago
Roundtrip flight included
Athens (ATH) to Chania (CHQ)
8/10 Very Good! (3 reviews)
The Noverian Scenic Crete 5 Star Hilltop Villa Resort & Spa

The Noverian Scenic Crete 5 Star Hilltop Villa Resort & Spa

5 out of 5
Save 100% on your flight
Price was $642, price is now $328 per person
$328
per person
Oct 13 - Oct 17
found 1 day ago
Roundtrip flight included
Athens (ATH) to Heraklion (HER)
9.4/10 Exceptional! (139 reviews)
We loved this resort and will definitely be back there next year. Staff were so friendly and delightful.

Reviewed on Jul 26, 2023

Creta Blue Boutique Hotel

Creta Blue Boutique Hotel

4 out of 5
Save 100% on your flight
Price was $841, price is now $434 per person
$434
per person
Oct 7 - Oct 11
found 1 day ago
Roundtrip flight included
Athens (ATH) to Heraklion (HER)
9.4/10 Exceptional! (239 reviews)
Gorgeous hotel with wonderful staff in a lovely village full of charm and delightful restaurants and bars.

Reviewed on Jun 26, 2025

Kalypso Hotel

Kalypso Hotel

4 out of 5
Save 100% on your flight
Price was $749, price is now $395 per person
$395
per person
Oct 8 - Oct 13
found 8 hours ago
Roundtrip flight included
Athens (ATH) to Heraklion (HER)
7.8/10 Good! (26 reviews)
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Discover the most popular places to visit in Mesi

Rethymnon Venetian Port

Rethymnon Venetian Port

4.5/5(49 reviews)

Explore the waterfront in Old Town Rethymnon with a trip to Rethymnon Venetian Port. Wander the beautiful beaches and waterfront in the area.

Rethymnon Venetian Port
Roman remains amongst the newer buildings in Crete.

Rimondi Fountain

4/5(6 reviews)

After visiting Rimondi Fountain, make a plan to see the other sights and activities in Old Town Rethymnon. Wander the beautiful beaches and waterfront in the area.

Rimondi Fountain
Argyroupoli is known for the famous springs. The locals have taken advantage of the springs, respecting the surroundings and nature- by creating wonderful tavernas for visitors.

Argiroupoli Springs

Commune with nature and explore the great outdoors at Argiroupoli Springs during your travels in Argyroupoli. Wander the beautiful beaches in this relaxing area.

Argiroupoli Springs

What to do in Mesi

Having lunch at Santorini

Santorini Island Full-Day Tour from Crete

$210
per adult
Santorini Island Full-Day Tour from Crete
Gramvousa and Balos lagoon with transfer and lunch

Balos lagoon with transfer

$75
per adult
Balos lagoon with transfer
Elafonisi Beach Trip from Rethymno

Elafonisi Beach Trip from Rethymno

$58
per adult
Elafonisi Beach Trip from Rethymno
See all activities in Mesi

Mesi Hotel Deals

Grecotel Creta Palace

Grecotel Creta Palace

5 out of 5
Missiria, Rethymno, Crete Island
$289 nightly
The price is $346 total per night from Sep 13 to Sep 14
$346 total
Sep 13 - Sep 14
Total with taxes and fees
Grecotel Creta Palace
Nautilux Rethymno by Mage Hotels

Nautilux Rethymno by Mage Hotels

5 out of 5
Australon Polemiston 23, Rethymno, Crete
$179 nightly
The price is $221 total per night from Oct 4 to Oct 5
$221 total
Oct 4 - Oct 5
Total with taxes and fees
Nautilux Rethymno by Mage Hotels
Grecotel LUXME White

Grecotel LUXME White

5 out of 5
Kambos Pigis, Adelianos Kampos, Rethymno, Crete Island
$417 nightly
The price is $492 total per night from Oct 6 to Oct 7
$492 total
Oct 6 - Oct 7
Total with taxes and fees
Grecotel LUXME White
See all 4,475 properties in Mesi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Mesi vacation package cost?
Offering excellent value package deals from $265 on Expedia, you'll be thrilled with how little a vacation to Mesi costs! Expedia's packages make travel planning easier and your savings go further.
What are the cheapest months to go to Mesi?
You can typically find lower prices and better availability in November, December and January. Browse our cheap Mesi vacation packages and you could get some excellent off-season deals.
How many days is enough for Mesi?
The ideal duration for your Mesi vacation depends on what you'd like to see. Generally, a few days to a week will give you plenty of time to check out all the major attractions and explore some hidden gems along the way.
How to find the best Mesi package deals?
Use Expedia's handy filters to help you find some great Mesi package deals. When you start your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for Mesi package deals in the off-season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package as early as possible.
Is it cheaper to book a Mesi vacation as a package?
You can enjoy significant savings on your next Mesi break by booking a customized vacation package. Check the "Package" heading, then select your travel dates and destination to view the best airfares and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Mesi?
If you've got your Mesi vacation dates locked in, book early to snap up some fantastic deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spontaneous getaways? Our last-minute deals are great for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Mesi vacation packages?
If you're like us, you love jet-setting around the world but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the overall cost of your Mesi break over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.