O Brien Vacations from $248

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The Latest O Brien vacation packages

Price found within the past 48 hours. Click for updated prices.
Nature Coast Inn and Cottages

Nature Coast Inn and Cottages

3 out of 5
Price was $288, price is now $248 per person
$248
per person
Jan 8 - Jan 11
found 5 hours ago
Roundtrip flight included
Boston (BOS) to Gainesville (GNV)
9.2/10 Wonderful! (93 reviews)
Staff was nice anything you need they would help

Reviewed on Oct 29, 2025

Equus Inn Ocala

Equus Inn Ocala

2.5 out of 5
Save 100% on your flight
Price was $497, price is now $302 per person
$302
per person
Jan 25 - Jan 31
found 1 day ago
Roundtrip flight included
Boston (BOS) to Gainesville (GNV)
9/10 Wonderful! (1,638 reviews)
The water pressure was very low in the shower. The tv was not working.

Reviewed on Nov 5, 2025

Landing Apartments Newberry

Landing Apartments Newberry

4 out of 5
Price was $1,039, price is now $835 per person
$835
per person
Dec 17 - Dec 22
found 7 hours ago
Roundtrip flight included
Miami (MIA) to Gainesville (GNV)
10/10 Exceptional! (41 reviews)
Every thing was great

Reviewed on Oct 20, 2025

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 out of 5
Price was $849, price is now $708 per person
$708
per person
Dec 17 - Dec 22
found 8 hours ago
Roundtrip flight included
Miami (MIA) to Gainesville (GNV)
9.4/10 Exceptional! (1,014 reviews)
Convenient location off 95

Reviewed on Nov 6, 2025

Americas Best Value Inn Alachua

Americas Best Value Inn Alachua

2 out of 5
Price was $610, price is now $554 per person
$554
per person
Dec 17 - Dec 22
found 7 hours ago
Roundtrip flight included
Miami (MIA) to Gainesville (GNV)
4.8/10 (588 reviews)
Staff was helpful and so courteous..

Reviewed on Nov 4, 2025

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O Brien Hotel Deals

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

obrien
9.8/10 Exceptional! (28 reviews)
This was an absolutely delightful house on the water. Plenty of room for the kids to run, it didn't feel sketchy with the river nearby (if you're anxious like me and worried about kids near a river, there's a decent land barrier), tons of stuff to do at the house and nearby, gorgeous area and great ...

Reviewed on Oct 12, 2025

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Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr, Lake City, FL
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $94 total per night from Nov 16 to Nov 17
$94 total
Nov 16 - Nov 17
Total with taxes and fees
9/10 Wonderful! (1,046 reviews)
Yes, yes

Reviewed on Nov 3, 2025

Best Western Plus Lake City
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE, Lake City, FL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Nov 16 to Nov 17
$105 total
Nov 16 - Nov 17
Total with taxes and fees
8.6/10 Excellent! (1,006 reviews)
Check in was an extremely easy process with the pre-check in link. Friendly courteous staff. Room was clean and comfortable. Will definitely stay in the future

Reviewed on Nov 2, 2025

La Quinta Inn & Suite by Wyndham Lake City
See all 339 properties in O Brien
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best O Brien Vacation Packages

O Brien Essential Information

Language
English
Currency
U.S dollars

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Frequently asked questions

How much does an O Brien vacation package cost?
Offering great value package deals from $248 on Expedia, you'll be surprised at how little a vacation to O Brien costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to O Brien?
If you're hoping to book a cheap O Brien vacation package, consider planning a trip in January, April and June. You'll generally find lower prices on airfares and hotels during these quieter months — ideal for a budget-friendly break.
How many days is enough for O Brien?
The ideal length for your O Brien vacation depends on what you'd like to see. Typically, a few days to a week will give you time to go to all the major attractions and discover some hidden treasures along the way.
How to find the best O Brien package deals?
Landing a cheap O Brien package deal is a breeze with Expedia. After you've entered your preferred dates and destination under our "Packages" tab, set your budget range, apply a couple of filters and browse what's available. You can customize your search by "Popular locations," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most economical O Brien package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book an O Brien vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging flights and hotels separately. Better still, you can personalize your O Brien trip to match your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to O Brien?
If you're planning a spur-of-the-moment O Brien vacation, browse our last-minute deals that can be booked up to one week before you take off. Don't want to leave things to the last minute? You can land amazing deals on your flights and hotels by booking well in advance.
Does Expedia offer Book Now, Pay Later O Brien vacation packages?
If you're anything like us, you love going away but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your O Brien trip over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can snap up great vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.