
Prairie City Vacations from $273
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Your Prairie City Vacation
Take the hassle out of planning your next great adventure with a Prairie City vacation package. Whether you've come for its history, food or something else, there's an inexhaustible array of experiences to be had. Neal Smith National Wildlife Refuge is one of the famous attractions to include on your itinerary during a trip to Prairie City. Whoever you're escaping with and whatever your bank balance, your dream Prairie City vacation is just a few clicks away with Expedia.
The Latest Prairie City vacation packages
Price found within the past 48 hours. Click for updated prices.

AmericInn by Wyndham Ankeny/Des Moines
Price was $333, price is now $273 per person
$273
per person
Oct 22 - Oct 25
found 10 hours ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
8/10 Very Good! (784 reviews)
Is a nice hotel with a decent size poll and a hut tub, grate for kids. However, there is no elevator and the pool area need some renovations.
Reviewed on Aug 18, 2025



GrandStay Hotel & Suites
Price was $354, price is now $311 per person
$311
per person
Oct 22 - Oct 25
found 10 hours ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
9.4/10 Exceptional! (379 reviews)
All was really fine -- the one huge glitch we were charged 3 times for the room accidentally, but then it took 3 days and multiple promises to fix it, before it finally got handled. so there is really only one issue - management do what you said you'd do, when you said you'd do it.
Reviewed on Sep 3, 2025

Hampton Inn & Suites Des Moines Downtown
Downtown Des Moines
Price was $452, price is now $398 per person
$398
per person
Oct 22 - Oct 25
found 10 hours ago
Roundtrip flight included
Denver (DEN) to Des Moines (DSM)
8.6/10 Excellent! (1,004 reviews)
The expedia website says it can sleep 5 people in the room, however it cannot sleep 5 and the room isn't ADA compliant big enough to legally fit a roll away bed in it
Reviewed on Aug 31, 2025
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See all available trips from Columbus to Prairie City
View all tripsDiscover the most popular places to visit in Prairie City

Neal Smith National Wildlife Refuge
5/5(2 reviews)
You can spend time exploring the galleries in Neal Smith National Wildlife Refuge during your trip to Prairie City. While you're in the area, wander around the natural setting.
Prairie City Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $156 total per night from Sep 7 to Sep 8
$156 total
Sep 7 - Sep 8
Total with taxes and fees

Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave, Des Moines, IA
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $82 total per night from Sep 6 to Sep 7
$82 total
Sep 6 - Sep 7
Total with taxes and fees

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
5000 Merle Hay Rd, Urbandale, IA
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $87 total per night from Sep 17 to Sep 18
$87 total
Sep 17 - Sep 18
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.