Prairie City Vacations from $578

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Your Prairie City Vacation

Take the hassle out of planning your next great adventure with a Prairie City vacation package. Whether you've come for its history, food or something else, there's an inexhaustible array of experiences to be had. Neal Smith National Wildlife Refuge is one of the famous attractions to include on your itinerary during a trip to Prairie City. Whoever you're escaping with and whatever your bank balance, your dream Prairie City vacation is just a few clicks away with Expedia.

The Latest Prairie City vacation packages

Price found within the past 48 hours. Click for updated prices.
Quality Inn & Suites Des Moines - Merle Hay Road

Quality Inn & Suites Des Moines - Merle Hay Road

2.5 out of 5
Lovington
Price was $665, price is now $578 per person
$578
per person
Mar 9 - Mar 16
found 16 hours ago
Roundtrip non-stop flight included
Boise (BOI) to Des Moines (DSM)
7.6/10 Good! (1,000 reviews)
The room was nicely made up. Everything looked clean. I did appreciate that the breakfast was offered at 6am on Saturday, as I needed to leave that morning by 6:45. A couple things as a heads up. The pet fee was $25, not the $20 stated online. Also, they require a deposit at check-in. The sign on the counter stated $100 but, I was charged $50 (which I did get back). All in all, it was a good place to stay the night and rest.

Reviewed on Jan 22, 2026

Hampton Inn & Suites Ankeny

Hampton Inn & Suites Ankeny

2.5 out of 5
Price was $775, price is now $630 per person
$630
per person
Mar 9 - Mar 16
found 16 hours ago
Roundtrip non-stop flight included
Boise (BOI) to Des Moines (DSM)
8.8/10 Excellent! (470 reviews)
Convenient location and super clean with great breakfast options.

Reviewed on Dec 30, 2025

Qube Hotel

Qube Hotel

2.5 out of 5
Price was $903, price is now $769 per person
$769
per person
Mar 9 - Mar 16
found 16 hours ago
Roundtrip non-stop flight included
Boise (BOI) to Des Moines (DSM)
8.4/10 Very Good! (726 reviews)
Great staff! Enjoyed our stay.

Reviewed on Dec 3, 2025

Comfort Inn & Suites Ankeny - Des Moines

Comfort Inn & Suites Ankeny - Des Moines

2.5 out of 5
Price was $851, price is now $734 per person
$734
per person
Mar 9 - Mar 16
found 16 hours ago
Roundtrip non-stop flight included
Boise (BOI) to Des Moines (DSM)
8.8/10 Excellent! (708 reviews)
Slept well. Comfortable beds and great room

Reviewed on Dec 1, 2025

My Place Hotel - Ankeny/ Des Moines, IA

My Place Hotel - Ankeny/ Des Moines, IA

3 out of 5
Price was $694, price is now $604 per person
$604
per person
Mar 9 - Mar 16
found 16 hours ago
Roundtrip non-stop flight included
Boise (BOI) to Des Moines (DSM)
9/10 Wonderful! (758 reviews)
Friendly staff & a clean, welcoming facility! We’ll definitely be staying here again.

Reviewed on Jan 23, 2026

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Discover the most popular places to visit in Prairie City

Nice trails to walk.

Neal Smith National Wildlife Refuge

You can spend time exploring the galleries in Neal Smith National Wildlife Refuge during your trip to Prairie City. While you're in the area, wander around the natural setting.

Neal Smith National Wildlife Refuge

Prairie City Hotel Deals

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $161 total per night from Feb 1 to Feb 2
$161 total
Feb 1 - Feb 2
Total with taxes and fees
9.4/10 Exceptional! (1,075 reviews)
Loved this property! The staff was extremely helpful. The room and bathroom were very nice. We enjoyed our stay very much!

Reviewed on Jan 19, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Jan 27 to Jan 28
$100 total
Jan 27 - Jan 28
Total with taxes and fees
9.2/10 Wonderful! (1,004 reviews)
Clean modern rooms, hallways, and lobby. Loved not having an alarm clock in the room as many times they are pre set for the alarm from the last visitor. I loved how the hallway door had a barrier all the way down to the floor so you could not see the hallway light underneath it.

Reviewed on Jan 18, 2026

Home2 Suites by Hilton Des Moines at Drake University
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $189 total per night from Jan 25 to Jan 26
$189 total
Jan 25 - Jan 26
Total with taxes and fees
9.6/10 Exceptional! (1,025 reviews)
Loved it

Reviewed on Jan 18, 2026

Des Lux Hotel
See all 609 properties in Prairie City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Prairie City Vacation Packages

Prairie City Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Des Moines Intl. Airport (DSM)
Population
1,700
Top Sights
Neal Smith National Wildlife Refuge, Toad Valley Golf Course and Valle Drive In

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Frequently asked questions

How much does a Prairie City vacation package cost?
You'll find cheap prices from $578 on Expedia for your Prairie City getaway. However, factors like the hotel choice, length of stay and season will influence how much your vacation to Prairie City costs.
What are the cheapest months to go to Prairie City?
You can generally find reduced prices and better availability in November, December and January. Browse our cheap Prairie City vacation packages and you could land some great off-season deals.
How many days is enough for Prairie City?
Generally, a handful of days is enough to see the main attractions during your Prairie City vacation. But if you prefer to have time to chill out or go on day trips, think about extending your trip.
How to find the best Prairie City package deals?
Start your search for a Prairie City package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Popular locations," to tailor the results to your exact needs. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the ideal Prairie City package deal straight away, just change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Prairie City escape off to a flying start.
Is it cheaper to book a Prairie City vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your car rental, hotel and flight into one great-value price and you could save hundreds of dollars. You'll typically score a better deal than booking each component separately. And you'll still get the freedom to create a customized Prairie City vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Prairie City?
If you've got your Prairie City vacation dates confirmed, book as early as you can to snap up some outstanding deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spontaneous trips? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Prairie City vacation packages?
Jet off on your dream trip to Prairie City with Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or wait until your next paycheck — we've joined forces with online lender Affirm to give you more flexibility and choice. Our vacation packages with payment plans allow you to spread the total cost over 3, 6 or 12 months. With no hidden or late payment fees, you can easily stay on budget and snap up cheap deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.