Prairie Home Vacations from $220

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The Latest Prairie Home vacation packages

Price found within the past 48 hours. Click for updated prices.
Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

$220
per person
Nov 19 - Nov 21
found 1 day ago
Roundtrip flight included
Denver (DEN) to Columbia (COU)
5.6/10 (411 reviews)
Holiday Inn Express & Suites Kingdom City by IHG

Holiday Inn Express & Suites Kingdom City by IHG

$544
per person
Nov 20 - Nov 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to Columbia (COU)
9.4/10 Exceptional! (569 reviews)
Very nice place to stay was very quiet and very convenient

Reviewed on Sep 3, 2026

Capital O Amerihost Inn and Suites Fulton Hwy 54 MO

Capital O Amerihost Inn and Suites Fulton Hwy 54 MO

$408
per person
Nov 20 - Nov 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to Columbia (COU)
5.6/10 (497 reviews)
Days Inn by Wyndham Mexico

Days Inn by Wyndham Mexico

$506
per person
Nov 20 - Nov 22
found 11 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Columbia (COU)
7/10 Good! (308 reviews)
No pool.

Reviewed on Sep 2, 2026

Capital O Amerihost Inn and Suites Kingdom City Hwy 54 MO

Capital O Amerihost Inn and Suites Kingdom City Hwy 54 MO

$450
per person
Nov 20 - Nov 22
found 1 day ago
Roundtrip non-stop flight included
Denver (DEN) to Columbia (COU)
6.6/10 (373 reviews)
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Prairie Home Hotel Deals

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$59 nightly
$67 total
Sep 21 - Sep 22
Total with taxes and fees
8.2/10 Very Good! (1,001 reviews)
"Good location, friendly staff. Big mini fridge in the room! I wish the vending machine had bottled water though. Or maybe just keeping a few in the room. The water fountain had a dispenser to fill a bottle but it’s not the same. Overall I’d stay here again. The price is hard to beat!"

Reviewed on Sep 4, 2026

Baymont by Wyndham Columbia, MO
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3100 Interstate 70 Dr. SE Columbia MO
$94 nightly
$106 total
Sep 13 - Sep 14
Total with taxes and fees
Drury Plaza Hotel Columbia East
Hotel Blu

Hotel Blu

3402 Interstate 70 Dr SE Columbia MO
Fully refundableReserve now, pay when you stay
$46 nightly
$52 total
Sep 8 - Sep 9
Total with taxes and fees
6.8/10 (172 reviews)
"You get what you pay for. The price was cheap but the room was still not worth it. Everything was dirty and run down. The refrigerator was not working. We asked to have someone fix it but no one did. Seldom was there anyone at the front desk. We had to check in using a kiosk instead of talking to ..."

Reviewed on Sep 4, 2026

Hotel Blu
See all 244 properties in Prairie Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Prairie Home Vacation Packages

Prairie Home Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Columbia Regional Airport (COU)
Top Sights
Hail Ridge Golf Course and Warm Springs Ranch

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Frequently asked questions

How much does a Prairie Home vacation package cost?
You'll find cheap prices from $220 on Expedia for your Prairie Home break. However, factors like the season, choice of hotel and length of stay will determine how much your vacation to Prairie Home costs.
What are the cheapest months to go to Prairie Home?
December, January and February are great times to look for cheap Prairie Home vacation packages. Traveling in quieter periods means you'll typically find better prices on hotels and flights.
How many days is enough for Prairie Home?
With a well-planned schedule, you can easily tick off the top Prairie Home attractions in a handful of days. But if you want to discover lesser-known spots or go on day trips, consider booking your Prairie Home vacation for longer.
How to find the best Prairie Home package deals?
Use Expedia's filters to help you find some tempting Prairie Home package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or search for Prairie Home package deals in the off-peak season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your vacation package well in advance.
Is it cheaper to book a Prairie Home vacation as a package?
You can enjoy significant savings on your Prairie Home escape by booking a tailored vacation package. Click on the "Package" heading, then select your travel dates and destination to see the best airfares and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Prairie Home?
If you're considering a spontaneous Prairie Home trip, check out our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can find amazing deals on your flights and hotels by booking ahead.
Does Expedia offer Book Now, Pay Later Prairie Home vacation packages?
Jet off on your perfect escape to Prairie Home with Expedia's Book Now, Pay Later vacations. There's no need to save up or wait until payday — we've joined forces with online lender Affirm to offer you flexibility and choice. Our vacation packages with payment plans let you spread the total cost over 3, 6 or 12 months. With no hidden charges or late payment fees, you can easily stick to your budget and snag great deals before they sell out.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.