Title: Top 10 Hotels in Puxico, MO from $51 - Competitive Prices | Expedia.com

[Vacation Rentals in Puxico](https://expedia.com/Puxico-Vacation-Rentals.d553248634983343452.Travel-Guide-VacationRentals)[Car Rentals in Puxico](https://expedia.com/Car-Rentals-In-Puxico.d553248634983343452.Car-Rental-Guide)[Puxico Vacation Packages](https://expedia.com/Puxico.d553248634983343452.Destination-Travel-Guides)

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## Go beyond your typical stay in Puxico

Pool

[](https://www.expedia.com/Hotel-Search?destination=Puxico%2C+Missouri%2C+United+States+of+America&regionId=553248634983343452&latLong=36.949775%2C-90.158434&adults=2&startDate=2026-02-19&d1=2026-02-19&endDate=2026-02-21&d2=2026-02-21&amenities=POOL)

Family friendly

[](https://www.expedia.com/Hotel-Search?destination=Puxico%2C+Missouri%2C+United+States+of+America&regionId=553248634983343452&latLong=36.949775%2C-90.158434&adults=2&startDate=2026-02-19&d1=2026-02-19&endDate=2026-02-21&d2=2026-02-21&travelerType=family_friendly)

Pet friendly

[](https://www.expedia.com/Hotel-Search?destination=Puxico%2C+Missouri%2C+United+States+of+America&regionId=553248634983343452&latLong=36.949775%2C-90.158434&adults=2&startDate=2026-02-19&d1=2026-02-19&endDate=2026-02-21&d2=2026-02-21&amenities=PETS)

## Check prices for these dates

Tonight

[Feb 5 - Feb 6](https://www.expedia.com/Hotel-Search?regionId=553248634983343452&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=553248634983343452&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=553248634983343452&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=553248634983343452&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Puxico hotels

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b034b164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/239bd50a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/a3a28e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/fa51e0ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Poplar Bluff

[](https://www.expedia.com/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information)

Poplar Bluff

9.2/10

Wonderful

(987 reviews)

"Great location and room "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Curtis

$94 nightly

$106 total

Feb 10 - Feb 11

Total with taxes and fees

[](https://www.expedia.com/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information)

![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/8f51ba4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/1e3aea9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/0a692e3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/419f7292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Poplar Bluff by IHG

[](https://www.expedia.com/Poplar-Bluff-Hotels-Holiday-Inn-Poplar-Bluff.h1222183.Hotel-Information)

Poplar Bluff

8.8/10

Excellent

(719 reviews)

"Amazing place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mladen

$110 nightly

$124 total

Feb 10 - Feb 11

Total with taxes and fees

[](https://www.expedia.com/Poplar-Bluff-Hotels-Holiday-Inn-Poplar-Bluff.h1222183.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/cc7b340b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/bf46ac12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/8b122520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Poplar Bluff

[](https://www.expedia.com/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information)

Poplar Bluff

9.4/10

Exceptional

(873 reviews)

"The size of the room. The staff were great. The room was very clean. Will definitely stay there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brenda

$108 nightly

$122 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information)

![Coffee service](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/22960908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/412c9f32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/a07fa840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchenette](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/8d2b66d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Poplar Bluff, MO

[](https://www.expedia.com/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

Poplar Bluff

8.0/10

Very Good

(1,000 reviews)

"Very clean and staff was very friendly!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sherry

$49 nightly

$51 total

Feb 6 - Feb 7

Total with taxes and fees

[](https://www.expedia.com/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/d3cfa5fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/665a33a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/f47e0ea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/d18ea228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn By Hilton Dexter

[](https://www.expedia.com/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information)

Dexter

10/10

Exceptional

(10 reviews)

"Great stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ashley

$98 nightly

$110 total

Feb 11 - Feb 12

Total with taxes and fees

[](https://www.expedia.com/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/b0632430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![39-inch LCD TV with cable channels, TV](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/51bc20b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/f6482ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/bc31acbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Poplar Bluff

[](https://www.expedia.com/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information)

Poplar Bluff

9.4/10

Exceptional

(800 reviews)

"Would stay again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

$106 nightly

$118 total

Feb 12 - Feb 13

Total with taxes and fees

[](https://www.expedia.com/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/a0829ae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/c0aef459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double Room | Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/f646a9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/145de6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### EC Reed's Mercantile and Hotel

[](https://www.expedia.com/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information)

Marble Hill

9.6/10

Exceptional

(84 reviews)

"Cute room, great food, fun soda fountain and friendly owners! Will return! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Leslie

$102 nightly

$112 total

Feb 16 - Feb 17

Total with taxes and fees

[](https://www.expedia.com/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8be70c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/eea0b1f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Accessible, Non Smoking | Desk, blackout drapes, iron/ironing board, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/d5132360.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/7385d4a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travelodge by Wyndham Dexter

[](https://www.expedia.com/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information)

Dexter

7.6/10

Good

(393 reviews)

"Clean room, friendly staff and quiet stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Margo

$92 nightly

$103 total

Feb 22 - Feb 23

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/80000/79500/79403/1db8fd06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking | Desk, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/80000/79500/79403/a73d6a9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking | Desk, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/80000/79500/79403/a754d6e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/80000/79500/79403/1e44f2fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn Poplar Bluff North

[](https://www.expedia.com/Poplar-Bluff-Hotels-Comfort-Inn-Poplar-Bluff-North.h79403.Hotel-Information)

Poplar Bluff

7.8/10

Good

(404 reviews)

"Everything is fine "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bob

$96 nightly

$109 total

Feb 13 - Feb 14

Total with taxes and fees

[](https://www.expedia.com/Poplar-Bluff-Hotels-Comfort-Inn-Poplar-Bluff-North.h79403.Hotel-Information)

![Breakfast area](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/f3b3697d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/df5fef26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/1413eaea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/w2304h1533x0y0-5c6ba836.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Dexter Inn

[](https://www.expedia.com/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information)

Dexter

7.0/10

Good

(334 reviews)

"Room was nice and spacious."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rebecca

$79 nightly

$89 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/40000000/39450000/39440300/39440279/10259602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/40000000/39450000/39440300/39440279/9dd5e5a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin | Desk, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/40000000/39450000/39440300/39440279/8df6c129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/40000000/39450000/39440300/39440279/dc88ded9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bullwinkles Rustic Lodge

[](https://www.expedia.com/Poplar-Bluff-Hotels-Bullwinkles-Rustic-Lodge.h39440279.Hotel-Information)

Poplar Bluff

8.4/10

Very Good

(213 reviews)

"Had to "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brenda

[](https://www.expedia.com/Poplar-Bluff-Hotels-Bullwinkles-Rustic-Lodge.h39440279.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/a26934b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/49fa46e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/2b360823.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/3340c554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Poplar Bluff Missouri

[](https://www.expedia.com/Poplar-Bluff-Hotels-Super-8-By-Wyndham-Poplar-Bluff-Missouri.h855304.Hotel-Information)

Poplar Bluff

6.6/10

(633 reviews)

"Very clean and staff was great"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dawn

$51 nightly

$58 total

Mar 6 - Mar 7

Total with taxes and fees

[](https://www.expedia.com/Poplar-Bluff-Hotels-Super-8-By-Wyndham-Poplar-Bluff-Missouri.h855304.Hotel-Information)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/caa808f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/59b72b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/cb936040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/440000/437700/437691/e5416d3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge Dexter

[](https://www.expedia.com/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information)

Dexter

6.8/10

(253 reviews)

"Room was clean, staff was AMAZING breakfast was false advertising as they don’t have hot breakfast just things like cereal."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jessica

$59 nightly

$67 total

Mar 7 - Mar 8

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Econo-Lodge-Dexter.h437691.Hotel-Information)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/1eb5943b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/415149fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/81d44800.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152272/fb2e4094.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### OYO Hickory House Inn

[](https://www.expedia.com/Sikeston-Hotels-Hickory-House-Inn.h1152272.Hotel-Information)

Dexter

5.6/10

(135 reviews)

"We enjoyed every moment of our stay. Wonderful service—everyone was friendly and helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Albert

$57 nightly

$63 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Hickory-House-Inn.h1152272.Hotel-Information)

![Free self parking](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1906x0y7-f34c7d0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1905x0y7-6be09486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2880h1907x0y6-58887435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Non Smoking | Bathroom | Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/24000000/23270000/23265800/23265745/w2274h1520x153y0-deab61df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  OYO Malden Airport Inn

[](https://www.expedia.com/Malden-Hotels-Malden-Airport-Inn.h23265745.Hotel-Information)

Malden

7.0/10

Good

(68 reviews)

"Clean room, quiet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

$47 nightly

$50 total

Mar 4 - Mar 5

Total with taxes and fees

[](https://www.expedia.com/Malden-Hotels-Malden-Airport-Inn.h23265745.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20&regionId=553248634983343452&adults=2&sort=RECOMMENDED&openPlayBack=true)

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## Learn more about Puxico

Check out the local area in Puxico—home to attractions like Mark Twain National Forest and Mingo Wilderness.

[See all hotels in Puxico](https://www.expedia.com/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20&adults=2&regionId=553248634983343452)

![Great place for sunrises, Bald Eagles in the winter, and Milkyway shots. ](https://images.trvl-media.com/place/553248634983343452/de6c5278-53d4-4238-882c-19c2c1cec581.jpg?impolicy=fcrop&w=309&h=400&p=1&q=high)

Photo by Mike McClain 

## Top Puxico Hotel Reviews

![Dexter Inn](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/4768517d_y.jpg)

### Dexter Inn

10/10 Excellent

"Nice rooms, friendly staff, "

[](https://expedia.com/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information)

![Fairfield Inn & Suites by Marriott Poplar Bluff](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720_y.jpg)

### Fairfield Inn & Suites by Marriott Poplar Bluff

10/10 Excellent

"Very clean . Every staff member was genuinely friendly and cared about your needs. Very fast check in/out. Breakfast was better than most. Great coffee. "

[](https://expedia.com/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information)

![Drury Inn & Suites Poplar Bluff](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b034b164_y.jpg)

### Drury Inn & Suites Poplar Bluff

10/10 Excellent

"Friendly and helpful staff, fast check-in, great facilities, clean rooms and comfy bed! Highly recommended! "

[](https://expedia.com/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information)

![Hampton Inn By Hilton Dexter](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/w3836h2556x4y4-c3d811b2_y.jpg)

### Hampton Inn By Hilton Dexter

10/10 Excellent

"Newly constructed- comfortable lobby. Friendly staff. Comfy beds with large flat screen TV."

[](https://expedia.com/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information)

![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg)

### Motel 6 Poplar Bluff, MO

10/10 Excellent

"The stay this time was just wonderful. The staff was more than helpful when we needed extra things and especially when we got stuck for two extra days from the snow. Normally we just get a regular room but this time decided to do a kitchenette. Best decision ever. Made the hallway smell like bacon but no complaints. Thank you for a wonderful staff. I wish I could remember names so I could give praise to the lady who went up and down the hallway getting stuff for us. She told us it was her job but she gave extra attention to detail. Thank you whoever you are. Wish we could’ve tip more!"

[](https://expedia.com/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

![Hampton Inn Poplar Bluff](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d_y.jpg)

### Hampton Inn Poplar Bluff

10/10 Excellent

"Clean room, good menu selections, great staff"

[](https://expedia.com/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information)

![Super 8 by Wyndham Poplar Bluff Missouri](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/29f9134c_y.jpg)

### Super 8 by Wyndham Poplar Bluff Missouri

10/10 Excellent

"Will be staying again. Thank you "

[](https://expedia.com/Poplar-Bluff-Hotels-Super-8-By-Wyndham-Poplar-Bluff-Missouri.h855304.Hotel-Information)

![Shop House located 8 miles from Otter Slough Conservation Area](https://images.trvl-media.com/lodging/101000000/100180000/100176800/100176703/eb6bb38f_y.jpg)

### Shop House located 8 miles from Otter Slough Conservation Area

10/10 Excellent

"Close to town, clean, friendly owner."

[](https://expedia.com/Dexter-Hotels-Shop-House-Located-8-Miles-From-Otter-Slough-Conservation-Area.h100176703.Hotel-Information)

![Private lake, beach & hot tub,  romantic getaway or family vaca](https://images.trvl-media.com/lodging/90000000/89720000/89711400/89711320/c3950ef0_y.jpg)

### Private lake, beach & hot tub, romantic getaway or family vaca

10/10 Excellent

"Very welcoming and comfortable. Host was very responsive and accommodating. Would definitely stay there again! "

[](https://expedia.com/Wappapello-Hotels-Private-Lake.h89711320.Hotel-Information)

## More cheap stays in Puxico

![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

$49 nightly

$51 total

Feb 6 - Feb 7

Total with taxes and fees

7.8/10 Good! (1,000 reviews)

[](https://expedia.com/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

![Super 8 by Wyndham Poplar Bluff Missouri](https://images.trvl-media.com/lodging/1000000/860000/855400/855304/29f9134c_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Super 8 by Wyndham Poplar Bluff Missouri

2831 N Westwood Blvd Poplar Bluff MO

$51 nightly

$58 total

Mar 6 - Mar 7

Total with taxes and fees

6.4/10 (633 reviews)

[](https://expedia.com/Poplar-Bluff-Hotels-Super-8-By-Wyndham-Poplar-Bluff-Missouri.h855304.Hotel-Information)

![Dexter Inn](https://images.trvl-media.com/lodging/1000000/860000/856200/856148/4768517d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Dexter Inn

1807 W Business US Highway 60 Dexter MO

$79 nightly

$89 total

Mar 8 - Mar 9

Total with taxes and fees

6.8/10 (334 reviews)

[](https://expedia.com/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information)

![Travelodge by Wyndham Dexter](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8be70c86_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Travelodge by Wyndham Dexter

1608 E Business US 60 Dexter MO

$92 nightly

$103 total

Feb 22 - Feb 23

Total with taxes and fees

7.4/10 Good! (392 reviews)

[](https://expedia.com/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information)

![Hampton Inn Poplar Bluff](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff MO

$106 nightly

$118 total

Feb 12 - Feb 13

Total with taxes and fees

9.2/10 Wonderful! (800 reviews)

[](https://expedia.com/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information)

![Fairfield Inn & Suites by Marriott Poplar Bluff](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Fairfield Inn & Suites by Marriott Poplar Bluff

3109 Oak Grove Poplar Bluff MO

$108 nightly

$122 total

Feb 12 - Feb 13

Total with taxes and fees

9.2/10 Wonderful! (873 reviews)

[](https://expedia.com/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information)

## Hotels in Puxico with star-rating

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

7 properties

[](https://expedia.com/3Star-Puxico-Hotels.s30-0-d553248634983343452.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

14 properties

[](https://expedia.com/2Star-Puxico-Hotels.s20-0-d553248634983343452.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### What is the best area to stay in Puxico?

> This area is the heart of Puxico, offering convenient access to local businesses and community gathering spots. You'll find the town's main park, public services, and local eateries within easy reach. It's a straightforward layout, making it simple to navigate for visitors.
> 
>   
> For families, staying in this central area is ideal due to its proximity to the community park, which often hosts local events and provides open spaces for recreation.

### When is the best time to go to Puxico?

> Spring offers mild temperatures, making it comfortable for outdoor activities like exploring the nearby Mingo National Wildlife Refuge. You'll find the local flora blooming and wildlife more active during these months. It's a great time for nature enthusiasts and those looking for a peaceful getaway.
> 
>   
> Fall also provides agreeable weather with cooler temperatures and the added beauty of changing leaves. This season is ideal for enjoying scenic drives through the surrounding countryside and participating in local harvest festivals if they are scheduled.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Puxico hotel booking with Expedia?

> \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

### How much is the nightly rate at a Puxico hotel?

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