
San Francesco Vacations from $620
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your San Francesco Vacation
Organizing your next adventure just got a whole lot simpler with a vacation package to San Francesco. Experience everything this neighborhood has to offer while making wonderful memories you'll replay for years. Can't wait to get out and see the sights during your trip to San Francesco? Be sure to check out nearby attractions like Tonnarella, Piazza Plebiscito and Piazza della Repubblica. Stop daydreaming and start doing. When it's time to lock in your next vacation to San Francesco, Expedia is here to help.
The Latest San Francesco Vacation Packages



Grand Hotel et Des Palmes
Reviewed on Nov 10, 2025


Porta di Castro Boutique Hotel & Spa
Reviewed on Nov 11, 2025
Where to stay in San Francesco

Giudecca
Though Giudecca might not have many top sights, you can venture to the surrounding area to see attractions like Royal Saint Nicholas and Piazza della Repubblica.
San Francesco Hotel Deals

Le Porte Del Tempo Dimora Storica
The room was lovely and spacious. The building itself is a delight with real charm and history and definitely part of the Old Town vibe. Breakfast was very good too.
Reviewed on Nov 10, 2025

Grand Hotel Palace
Hotel was a bit "tired" but a good value for the price
Reviewed on Oct 16, 2025

Baitan Hotel
everything is wonderful
Reviewed on Oct 6, 2025
Discover the most popular places to visit in San Francesco
St. Vitus on the Sea
Learn about the local history of Mazara del Vallo when you take a trip to St. Vitus on the Sea. Discover the area's countryside and monuments.
Royal Saint Nicholas
You can learn about the history of Mazara del Vallo with a trip to Royal Saint Nicholas. Discover the area's countryside and monuments.
Museum Satiro
You can spend time studying the exhibits at Museum Satiro in Mazara del Vallo. Make time to visit the monuments and churches while you're in the area.
Things to do

Quad tour between vineyards and the sea with a glass of wine.





















