San Juan de Dios Vacations from $142

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Your San Juan de Dios Vacation

From its shopping to its markets and cafes, there are loads of fabulous reasons to book a vacation package to San Juan de Dios. When you're ready to leave the everyday behind, this busy neighborhood has a spot just for you. Some leading nearby attractions to visit during your trip to San Juan de Dios include Hospicio Cabanas, Guadalajara Cathedral and Jalisco Stadium. No matter what your ideal San Juan de Dios vacation looks like, you can make it a reality with Expedia.

The Latest San Juan de Dios Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Casa 8

Casa 8

2 out of 5
Downtown Guadalajara
Save 100% on your flight
Price was $246, price is now $142 per person
$142
per person
Jan 16 - Jan 19
found 5 hours ago
Roundtrip flight included
Ciudad Juarez (CJS) to Guadalajara (GDL)
7.8/10 Good! (28 reviews)
Tribu Centro Histórico

Tribu Centro Histórico

3.5 out of 5
Downtown Guadalajara
Save 100% on your flight
Price was $308, price is now $165 per person
$165
per person
Dec 12 - Dec 15
found 6 hours ago
Roundtrip flight included
Ciudad Juarez (CJS) to Guadalajara (GDL)
7.4/10 Good! (49 reviews)
Hace un año me hospedé y fue un estancia agradable pero, en esta ocasión no. Estaba el loft sucio y descuidado por ejemplo, estaba un pedazo de piso de la escalera sobrepuesto, la sala estaba toda sucia y olía mal, el foco del patio estaba fundido, tuve que pedir una plancha, solo dejaron un cobertor pequeño para 3 camas y cuando le solicité más a la persona de limpieza me comentó que no, que no manejaban más que puras sábanas… Mala experiencia porque olía mal, a sucio

Reviewed on Aug 11, 2025

Hotel Alcazar

Hotel Alcazar

3.5 out of 5
Downtown Guadalajara
Save 100% on your flight
Price was $344, price is now $188 per person
$188
per person
Jan 16 - Jan 19
found 5 hours ago
Roundtrip flight included
Ciudad Juarez (CJS) to Guadalajara (GDL)
8.6/10 Excellent! (1,005 reviews)
The place wa clean and very close the historic area.

Reviewed on Oct 13, 2025

Hotel Don Quijote Plaza

Hotel Don Quijote Plaza

3 out of 5
Downtown Guadalajara
Save 100% on your flight
Price was $313, price is now $171 per person
$171
per person
Dec 12 - Dec 15
found 10 hours ago
Roundtrip flight included
Ciudad Juarez (CJS) to Guadalajara (GDL)
8.4/10 Very Good! (1,003 reviews)
Everything was good

Reviewed on Oct 17, 2025

Hotel Casino Plaza

Hotel Casino Plaza

3.5 out of 5
Downtown Guadalajara
Save 100% on your flight
Price was $290, price is now $162 per person
$162
per person
Jan 16 - Jan 19
found 5 hours ago
Roundtrip flight included
Ciudad Juarez (CJS) to Guadalajara (GDL)
9.4/10 Exceptional! (1,004 reviews)
Breakfast Buffet was kind of basic …

Reviewed on Oct 18, 2025

Where to stay in San Juan de Dios

Find the best San Juan de Dios areas and neighborhoods for the activities you enjoy most. Learn more about San Juan de Dios
Downtown Guadalajara

Downtown Guadalajara

1 out of top 10 points of interest in this area
4/5(1,327 area reviews)

Guadalajara’s historic center is a vibrant area where stories of the city’s past come to life at grand colonial landmarks, excellent museums and elegant squares.

Find hotels in Downtown Guadalajara

San Juan de Dios Hotel Deals

Hotel Riu Plaza Guadalajara

Hotel Riu Plaza Guadalajara

5 out of 5
Av. Lopez Mateos 830 Col. Chapalita, Guadalajara, JAL
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $129 total per night from Nov 17 to Nov 18
$129 total
Nov 17 - Nov 18
Total with taxes and fees
9/10 Wonderful! (4,051 reviews)
I loved the stay! Definitely will be coming back

Reviewed on Oct 25, 2025

Hotel Riu Plaza Guadalajara
Hotel Dali Ejecutivo

Hotel Dali Ejecutivo

3 out of 5
Av. Pedro Moreno N. 570 Col. Centro, Guadalajara, JAL
Fully refundableReserve now, pay when you stay
$31 nightly
The price is $38 total per night from Nov 10 to Nov 11
$38 total
Nov 10 - Nov 11
Total with taxes and fees
8.8/10 Excellent! (2,253 reviews)
We didn't eat breakfast or any food there.

Reviewed on Oct 21, 2025

Hotel Dali Ejecutivo
Hotel Velvet Plaza

Hotel Velvet Plaza

3.5 out of 5
Avenida Vallarta 2477, Colonia Arcos Vallarta, Guadalajara, JAL
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $74 total per night from Nov 1 to Nov 2
$74 total
Nov 1 - Nov 2
Total with taxes and fees
9.2/10 Wonderful! (3,291 reviews)
Great hotel! We stayed 4 nights and enjoyed our stay.

Reviewed on Oct 28, 2025

Hotel Velvet Plaza
See all 1,319 properties in San Juan de Dios
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in San Juan de Dios

Hospicio Cabanas showing heritage architecture and a castle

Hospicio Cabanas

Discover famous murals, admire fine architecture and explore the grounds of one of South America’s largest former hospitals at this World Heritage Site.

Hospicio Cabanas

Magno Centro Joyero

During your trip to Guadalajara, you can browse for the perfect souvenirs at Magno Centro Joyero. Attend a sporting event or visit the stunning cathedral in this culturally rich area.

Magno Centro Joyero

Mercado Libertad

During your visit to Guadalajara, you can enjoy retail therapy at Mercado Libertad. Check out the stunning cathedral and top-notch restaurants in this culturally rich area.

Mercado Libertad

Things to do

Mazamitla tour from Guadalajara with Mundo Aventura

Mazamitla tour from Guadalajara visiting Mundo Aventura

$49
per adult
88% of travellers recommend
Mazamitla tour from Guadalajara visiting Mundo Aventura
From Guadalajara to Chapala Lake: Funny and cultural tour

From Guadalajara to Chapala Lake: Funny and cultural tour

$33
per adult
96% of travellers recommend
From Guadalajara to Chapala Lake: Funny and cultural tour
Complete Tour on the Tequila Route from Guadalajara

Complete Tour on the Tequila Route from Guadalajara

$54
per adult
88% of travellers recommend
Complete Tour on the Tequila Route from Guadalajara
See all activities in Guadalajara
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.