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Our top choices for Santa Ana hotels

MOMORA DISTRITO SELVA

MOMORA DISTRITO SELVA
3.0 star property
Santa Ana
$282 nightly
The price is $286
Dec 25 - Dec 26
MOMORA DISTRITO SELVA

La Mision Posadas Hotel

La Mision Posadas Hotel
3.5 star property
Posadas
7.8 out of 10, Good, (134)
"I enjoyed the service I received from the staff, as well as the help with my suitcase up the stairs to my room. I loved the comfortable bed! Breakfast was limited, but adequate. "
United States
James
$53 nightly
The price is $55
Dec 25 - Dec 26
La Mision Posadas Hotel

Hotel Maitei Posadas

Hotel Maitei Posadas
3.5 star property
Posadas
8.2 out of 10, Very Good, (41)
"Very old mattresses, not comfortable sleeping, parts of the building seems abandoned "
United States
Fredy
$59 nightly
The price is $61
Jan 4 - Jan 5, 2026
Hotel Maitei Posadas

Hostel Sudaka

Hostel Sudaka
2.0 star property
Garupá
10.0 out of 10, Exceptional, (1)
$21 nightly
The price is $21
Dec 25 - Dec 26
Hostel Sudaka

Continental Posadas Hotel

Continental Posadas Hotel
3.5 star property
Posadas
7.8 out of 10, Good, (96)
"Nice place fore the price."
United States
Katiuska
Continental Posadas Hotel

Hostería Montes

Hostería Montes
3.0 star property
San Ignacio
10.0 out of 10, Exceptional, (1)
"Lugar acolhedor. Quarto limpo e cheiroso com cama confortável. Café da manhã a parte, saboroso e com preço justo."
Brazil
Ellen
$38 nightly
The price is $40
Dec 30 - Dec 31
Hostería Montes

Irová Apart Hotel

Irová Apart Hotel
3.0 star property
Posadas
9.6 out of 10, Exceptional, (4)
"Nuestra experiencia en el hotel fue muy grata, el personal siempre dispuesto a ayudar y las instalaciones súper cómodas, hicieron nuestra estadía muy confortable. Muchas gracias "
Argentina
Adrian
Irová Apart Hotel

BAGU URBANO

BAGU URBANO
3.0 star property
Posadas
8.2 out of 10, Very Good, (14)
"..."
United States
Rafael
$64 nightly
The price is $66
Jan 1 - Jan 2, 2026
BAGU URBANO

Hotel Grand Lago

Hotel Grand Lago
3.0 star property
Posadas
$65 nightly
The price is $67
Dec 25 - Dec 26
Hotel Grand Lago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Ana attractions

Top Santa Ana Hotel Reviews

More cheap stays in Santa Ana

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Cultural Immersion: Explore the charming streets and historic sites, offering a deep connection to the local culture.
  • Wellness Retreats: Indulge in rejuvenating body treatments and spa experiences for relaxation and rejuvenation.
  • Historical Attractions: Visit fascinating ruins and historic houses that provide rich cultural experiences.
  • Family-Friendly Activities: Enjoy fun outings at the nearby Santa Ana Zoo, perfect for family visits.
  • Diverse Accommodations: Choose from a variety of lodging options, from budget motels to vibrant hostels.

Find great hotels in and around Santa Ana

Santa Ana, Misiones Province, offers a variety of lodging options perfect for any traveler. Whether you're looking for a pet-friendly hotel, a budget-friendly motel, or a vibrant hostel experience, you'll find accommodations that cater to your needs. With a range of prices and amenities, from affordable motels to comfortable business-themed hotels, Santa Ana ensures a pleasant stay for everyone visiting this charming destination.

  • Continental Posadas Hotel: Offering a sophisticated blend of business and romance, the Continental Posadas Hotel is a 3.5-star gem located 19 miles from Santa Ana. Ideal for travelers seeking a city-themed getaway, this hotel provides numerous amenities tailored for business needs, including multiple meeting rooms. For couples looking for a romantic escape, the hotel features exclusive romance packages and limited-hour room service for an intimate dining experience. Nestled in the heart of the city, guests can enjoy convenient access to local attractions while indulging in a comfortable stay.
  • Sihostel: A budget-friendly option, Sihostel is a charming hostel located 8 miles from Santa Ana, perfect for pet-loving adventurers. Known for its welcoming atmosphere, this hostel allows pets onsite, making it an ideal choice for travelers wishing to bring their furry friends along. With a pet-friendly policy and amenities that cater to both budget-conscious guests and their pets, Sihostel stands out as a cozy and convenient base for exploring the area.
  • Al Kamar Lodge Spa: Nestled within Santa Ana, Al Kamar Lodge Spa is a tranquil retreat for those seeking relaxation and rejuvenation. This lodge features an extensive spa service that includes daily treatments, a sauna, and a hot tub, inviting guests to unwind in a serene environment. With a focus on wellness, Al Kamar Lodge Spa offers the perfect atmosphere for travelers looking to indulge in pampering and self-care, making it a fantastic choice for a spa-themed vacation.

Where to stay near Santa Ana

Santa Ana, Misiones Province, is a delightful destination for travelers seeking cultural immersion and wellness experiences. Explore the charming streets rich in history, where friendly locals welcome you. Discover vibrant neighborhoods that reflect the area's unique atmosphere. Nearby attractions offer a blend of historical significance and natural beauty, making Santa Ana a perfect base for your Argentine adventure. Embrace the local vibe and create unforgettable memories in this captivating region.

  • Loreto: Located approximately 4 miles from Santa Ana, Loreto offers a rich cultural experience for travelers. Known for its adventure and outdoor activities, this charming city attracts visitors year-round, with peak arrivals in January to February and November. While exploring, you can immerse yourself in its historic sites and ruins, which tell the story of the region's past. The laid-back atmosphere makes it an ideal spot for those looking to enjoy a blend of culture and nature.
  • San Ignacio: About 10 miles from Santa Ana, San Ignacio is a vibrant city that draws families and culture enthusiasts alike. This destination sees a moderate influx of visitors, particularly from December to February. San Ignacio boasts a variety of entertainment options, including a popular water park and relaxing spa treatments. The city's historic landmarks and ruins are must-see attractions that provide insight into the area's heritage, making it a great spot for family-friendly fun and cultural exploration.
  • Bonpland: Also situated 10 miles from Santa Ana, Bonpland is a city that invites visitors to delve into its cultural offerings. While travel numbers are steady throughout the year, the peak season occurs from December to February. Here, you can explore intriguing ruins and historic places that showcase the region's history. Bonpland is a fantastic choice for those seeking a culturally rich experience in a less crowded environment, allowing for a more intimate connection with the local heritage.

Things to do near Santa Ana

Santa Ana, located in Misiones Province, Argentina, is an ideal destination for culture-themed and wellness vacations. Visitors can indulge in rejuvenating body treatments and enjoy spa experiences. Key activities include sightseeing around Santa Ana, taking welcome breaks, and exploring day trips, making it perfect for spa enthusiasts looking to unwind and immerse themselves in the local culture.

Shopping

In Santa Ana, explore local markets for unique crafts and souvenirs. For a larger shopping experience, visit Shopping del Sol, located about 15 miles away, where you'll find a variety of shops and dining options. If you're up for a drive, check out the nearby shopping centers in Posadas for more choices.

Recreation

Experience the rejuvenating treatments at Aloe-Spa Salute per Aloe, located 22 miles from Santa Ana. Immerse yourself in a serene atmosphere designed for relaxation, where you can indulge in body treatments that promote wellness and tranquility, leaving you refreshed and revitalized.

Adventure

Experience the thrill of zip-lining through the lush canopies of Santa Ana's jungle. Explore the area's scenic trails while hiking, where you'll encounter diverse wildlife and stunning landscapes. For a unique touch, consider a boat tour on the Paraná River to enjoy the serene beauty of the surroundings.

Nightlife

Experience the vibrant nightlife in Santa Ana at Tiki Bar, where you can enjoy tropical cocktails and lively music. For a more relaxed vibe, visit Bar del Parque to savor local wines amidst a cozy atmosphere, perfect for unwinding after a day of exploring.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Ana

To save money on your trip to Santa Ana, consider traveling during the months of May, August, or October, when prices are lower. Sundays are the cheapest days to stay, while Mondays are the priciest. Utilize Expedia’s search tool to find budget-friendly hotel options and consider bundling your hotel, flights, and activities for better deals. Joining Expedia's One Key membership can provide additional discounts and cash back for future bookings. Explore the area on foot to save on public transport costs and enjoy free activities.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Ana are May, August and October, where the prices are slightly lower. This is in comparison to April, July and December, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Ana is Sunday. The most expensive day to stay in Santa Ana is Monday.
  • Find cheap hotels on Expedia: Make the most of Expedia’s search tool by customizing your options based on your budget, preferred destination, and the type of hotel you’re looking for. To find the best deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by putting together a package deal on Expedia that combines your Santa Ana hotel, flights, and activities.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions in and around Santa Ana

Santa Ana in Misiones Province, Argentina, is perfect for culture-themed and wellness vacations. Visitors can explore fascinating ruins and historic houses that provide rich cultural experiences. To enhance your stay, consider finding hotels near the Santa Ana Zoo, which adds a fun and family-friendly aspect to your trip. Whether you're seeking relaxation or cultural immersion, Santa Ana offers a delightful blend of attractions for every traveler.

  • San Ignacio Miní: Explore the captivating ruins of San Ignacio Miní, located 8 miles from Santa Ana. This UNESCO World Heritage site showcases the rich cultural history of the Jesuit missions, with stunning stone structures and lush surroundings that transport you back in time.
  • Casa de Horacio Quiroga: Visit the historic house of renowned writer Horacio Quiroga, also 8 miles away. This charming home reflects the life and works of the author, surrounded by beautiful gardens that inspired many of his stories, offering a unique glimpse into Argentine literature.
  • Nuestra Senora de Santa Ana: Discover the ruins of Nuestra Senora de Santa Ana, situated within the town. These historical remains highlight the area's colonial past and provide a peaceful setting for reflection and exploration of local heritage.

Best time to go to Santa Ana

The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Ana falls in January, when visitor numbers are moderately high and weather is mostly sunny with light rain. The coolest average temperature in Santa Ana falls in July, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January79.9°F (26.6°C)Light RainMostly SunnyModerately HighAverage
February79.2°F (26.2°C)Light RainMostly SunnyModerately HighAverage
March75.9°F (24.4°C)Light RainMostly SunnyAverageAverage
April70.5°F (21.4°C)Light RainMostly SunnyAverageSlightly High
May63.9°F (17.7°C)Light RainMostly SunnyModerately LowSlightly Low
June60.3°F (15.7°C)Light RainMostly SunnyModerately LowAverage
July59.9°F (15.5°C)Light RainMostly SunnyAverageSlightly High
August63.7°F (17.6°C)Light RainMostly SunnyModerately LowSlightly Low
September67.5°F (19.7°C)Light RainMostly SunnyAverageAverage
October70.9°F (21.6°C)Moderate RainMostly SunnyAverageSlightly Low
November74.5°F (23.6°C)Light RainMostly SunnyAverageAverage
December78.4°F (25.8°C)Light RainMostly SunnyModerately HighSlightly High

The nearest major airports for your trip to Santa Ana

To reach Santa Ana, Misiones Province, you can fly into Posadas (PSS-Libertador General Jose de San Martin), which is 24 miles away. This airport serves several airlines and offers convenient access to nearby accommodations. Recommended hotels include La Mision Posadas Hotel, a 3.5-star property located 2 miles from the airport; Continental Posadas Hotel, also rated 3.5 stars, situated 5 miles away; and Hotel Batista, a similarly rated hotel just 3 miles from the airport. Transportation options are available for easy access from these hotels to the airport, ensuring a smooth start to your vacation in Santa Ana.

Frequently asked questions

What is the best area to stay in Santa Ana?
For a convenient and focused visit to Santa Ana, the best area to stay is near the central plaza, Plaza San Martin, and the Jesuit Ruins of Santa Ana.

This central area offers easy walking access to Santa Ana's main attractions. You'll find the town's small selection of local eateries and shops clustered around the plaza. The Jesuit Ruins, a UNESCO World Heritage site, are just a short walk away, making it ideal for visitors primarily interested in exploring this historical landmark.

Couples looking for a quiet and culturally rich experience will appreciate staying in this central part of Santa Ana. It allows for relaxed strolls to the ruins and a peaceful evening atmosphere, with local restaurants providing a taste of the region.

Travelers prioritizing historical exploration will find this area exceptionally convenient.
When is the best time to go to Santa Ana?
The best time to go to Santa Ana, Misiones Province, Argentina, is during the shoulder seasons of autumn (March to May) and spring (September to November).

These periods offer pleasant weather with moderate temperatures and less humidity, making it comfortable for exploring the Jesuit Ruins of Santa Ana, a UNESCO World Heritage site, and the surrounding natural attractions. You'll find fewer crowds compared to the peak summer months, allowing for a more relaxed experience.

For travelers who prefer outdoor activities and sightseeing without intense heat, autumn provides comfortable conditions for visiting the ruins and enjoying the lush Misiones landscape. The temperatures are generally mild, ideal for walking and exploring at your own pace.

Spring is also an excellent choice, as the weather is agreeable, and the region's flora is in full bloom.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Ana.
How can I save on a Santa Ana hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santa Ana hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Ana hotel?
Prices for hotels in Santa Ana often vary, but you can find a great deal from $21 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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