Santa Clara Vacations from $1,174
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Santa Clara Vacation
Planning your next escape just got easier with a vacation package to Santa Clara. Immerse yourself in the very best this neighborhood has to offer while creating beautiful memories that'll stay with you for years. Can't wait to head out and see the sights during your trip to Santa Clara? Be sure to stop by nearby attractions like Seville Cathedral, Alcázar and Plaza de España. Whatever your travel plans or budget, booking your ideal Santa Clara vacation is easy with Expedia.
The Latest Santa Clara Vacation Packages
Ocean Drive Sevilla
Reviewed on Jan 13, 2026
Eurostars Sevilla Boutique
Reviewed on Nov 17, 2025
Apartamentos Metrópolis Sevilla
Reviewed on Dec 23, 2025
Hotel Vincci Selección Unuk 5* GL
Reviewed on Jan 12, 2026
Where to stay in Santa Clara
Historical Center
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
Santa Clara Hotel Deals
Las Casas de la Judería, Sevilla Historic City Center
Gorgeous property. Great location.
Reviewed on Jan 11, 2026
Only YOU Hotel Sevilla
Check-in was a breeze working with Sara. She was amazing and super helpful. Room was perfect and could have not asked for a better experience. Unfortunately my only negative was the resturant on first floor. I went when it was not busy at all. The host sat me and then no one else came at all to take ...
Reviewed on Jan 9, 2026
Hotel Sevilla Center
A very clean and modern hotel. Close to all the major sites.
Reviewed on Jan 12, 2026
Discover the most popular places to visit in Santa Clara
Seville Cathedral
See Columbus’ tomb, artwork by Goya and Murillo and plenty of breathtaking architecture all within the largest Gothic cathedral in Europe.
Royal Alcázar of Seville
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Plaza de España
You can find out about the history of Paseo de Las Delicias when you stop by Plaza de España. Discover the acclaimed art scene and shops in this vibrant area.
Things to do
Cathedral & Alcázar of Seville Guided Tour Combo
Ticket for Casa de la Guitarra Flamenco Show
