Santa Croce Vacations from $1,003
Book a Hotel + Flight or Car together to unlock savings
Your Santa Croce Vacation
Our Santa Croce vacation packages are a fast and practical way to plan and reserve your next adventure. Uncover the true character of this unique neighborhood without the hassle of having to organize everything yourself. Some top nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can put your plans into action. Book your ultimate Santa Croce vacation now.
The Latest Santa Croce Vacation Packages
Price found within the past 48 hours. Click for updated prices.
- Aurum Firenze
Jan 12 - Jan 17Aurum Firenze + Flight
Historic Centre of Florence4 nights4.0 star property7.4/10 - Good (1,004 reviews)Roundtrip ā¢ New York (JFK) - Florence (FLR)JFK - FLR ā¢ 1 stop FLR - JFK ā¢ 1 stop$1,518$1,003found 1 day agoper traveler - The Place Firenze
Jan 2 - Jan 8The Place Firenze + Flight
Historic Centre of Florence5 nights5.0 star property9.8/10 - Exceptional (203 reviews)Roundtrip ā¢ Boston (BOS) - Florence (FLR)BOS - FCO ā¢ Nonstop FCO - BOS ā¢ 1 stop$3,177$2,229found 16 hours agoper traveler - Donati Luxury Tower Suites
Jan 15 - Jan 22Donati Luxury Tower Suites + Flight
Historic Centre of Florence6 nights5.0 star property9.8/10 - Exceptional (82 reviews)"Great location. Historical building. Rooms were stunning. Lovely breakfast box delivered daily. Nice staff. The only negative is the roof is ā¬250 per 2 hour booking, which I didn't expect, and would have been a reason for booking. Hence 4/5."Reviewed October 19, 2026Roundtrip ā¢ New York (JFK) - Florence (FLR)JFK - FLR ā¢ 1 stop FLR - JFK ā¢ 1 stop$2,952$2,186found 1 day agoper traveler - Hotel Berchielli
Jan 17 - Jan 23Hotel Berchielli + Flight
Historic Centre of Florence5 nights4.0 star property9.4/10 - Exceptional (1,000 reviews)Roundtrip ā¢ Boston (BOS) - Florence (FLR)BOS - FLR ā¢ 1 stop FLR - BOS ā¢ 1 stop$1,372$1,030found 1 day agoper traveler - Portrait Firenze - Lungarno Collection
Jan 2 - Jan 8Portrait Firenze - Lungarno Collection + Flight
Historic Centre of Florence5 nights5.0 star property9.8/10 - Exceptional (324 reviews)Roundtrip ā¢ Boston (BOS) - Florence (FLR)BOS - FCO ā¢ Nonstop FCO - BOS ā¢ 1 stop$3,408$2,669found 16 hours agoper traveler
Where to stay in Santa Croce
Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Learn more about Santa Croce
Historic Centre of Florence
Lose yourself in the Renaissance charm of Florenceās old town, where masterpieces by Brunelleschi and Giotto line up alongside cafĆ©s, gelato shops and trattorias.
Santa Maria Novella
Spend some time in an attractive neighborhood close to the city center that encompasses ancient buildings and churches and a large park of outstanding beauty.
Duomo
Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.
Photo by Giorgio Galeotti
Open Photo by Giorgio Galeotti
Photo by Michelle Maria
Open Photo by Michelle Maria
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Discover the most popular places to visit in Santa Croce
What to do near Santa Croce
City Sightseeing Florence Hop-on Hop-off Bus Tour
$26
per adult
74% of travelers recommend
The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery
$90
per adult
98% of travelers recommend
Accademia timed-entry Ticket with App Guide
$44
per adult
90% of travelers recommend
Santa Croce Hotel Deals
8.2 out of 10, Very good, (1,005 reviews)
8.2/10
Very good
(1,005 reviews)
"Buena ubicaciĆ³n cerca del tren y bus"
$111 nightly
The price is $138
$138 total
Nov 23 - Nov 24
Total with taxes and fees
9.4 out of 10, Exceptional, (1,006 reviews)
9.4/10
Exceptional
(1,006 reviews)
$162 nightly
The price is $194
$194 total
Dec 9 - Dec 10
Total with taxes and fees
La Maison du Sage
La Maison du SageSanta Croce
9.6 out of 10, Exceptional, (400 reviews)
9.6/10
Exceptional
(400 reviews)
"Breakfast was really expensive"
$105 nightly
The price is $129
$129 total
Nov 19 - Nov 20
Total with taxes and fees
8.6 out of 10, Excellent, (510 reviews)
8.6/10
Excellent
(510 reviews)
$83 nightly
The price is $106
$106 total
Dec 8 - Dec 9
Total with taxes and fees
Palazzo Firenze by Baglioni Hotels & Resorts
Palazzo Firenze by Baglioni Hotels & Resorts5.0 star property
Santa Croce
9.4 out of 10, Exceptional, (244 reviews)
9.4/10
Exceptional
(244 reviews)
$413 nightly
The price is $472
$472 total
Nov 17 - Nov 18
Total with taxes and fees
8.8 out of 10, Excellent, (292 reviews)
8.8/10
Excellent
(292 reviews)
$131 nightly
The price is $162
$162 total
Dec 9 - Dec 10
Total with taxes and fees
9.2 out of 10, Wonderful, (722 reviews)
9.2/10
Wonderful
(722 reviews)
$81 nightly
The price is $99
$99 total
Nov 9 - Nov 10
Total with taxes and fees
7.8 out of 10, Good, (801 reviews)
7.8/10
Good
(801 reviews)
"Was exactly what we needed, a close walk to everywhere we wanted to go and a friendly nice staff and hotel."
$73 nightly
The price is $93
$93 total
Dec 1 - Dec 2
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.