Santa Croce Vacations from $1,166
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Your Santa Croce Vacation
Our Santa Croce vacation packages are a fast and practical way to plan and reserve your next adventure. Uncover the true character of this unique neighborhood without the hassle of having to organize everything yourself. Some top nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can put your plans into action. Book your ultimate Santa Croce vacation now.
The Latest Santa Croce Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Ginori al DUOMO
Historic Centre of Florence
$1,166
per person
Nov 24 - Nov 28
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
8.8/10 Excellent! (61 reviews)
Fantastic stay, thank you for the upgrade, spacious, cool rooms. Great location, walk to the station and across the road is a convenience store and great restaurants and gelato in the same street
Reviewed on Sep 4, 2026
Aurum Firenze
Historic Centre of Florence
$1,233
per person
Oct 21 - Oct 27
found 15 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,003 reviews)
Breakfast was great. Our room was a little small but okay. Close to Mercato Centrale and Piazza del Duomo. Lots of great places to eat. Special mention to Trattoria Palle d’oro.
Reviewed on Sep 20, 2026
Grand Hotel Cavour
Historic Centre of Florence
$2,465
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.2/10 Wonderful! (1,004 reviews)
Lovely hotel and great position in Florence. Staff were friendly and helpful. Breakfast was lovely plenty of choice. Wouldn’t hesitate to stay there again. Perfect for the usual sightseeing !
Reviewed on Sep 15, 2026
Aurum Uffizi
Historic Centre of Florence
$1,189
per person
Oct 22 - Oct 27
found 15 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,001 reviews)
We had a terrible stay. The first night there the air conditioner leaked and most of my clothes were soaked as my suitcase was on the beach under the air conditioner! When I brought it to their attention. And asked for help on drying my clothes, They didn’t seem to care! Shower was also cold! Also brought this to their attention and again didn’t care. I asked for a small compensation for the inconvenience and they said no!!! None of my what’s app messages were answered!! My whole stay was awful! I would not recommend !
Reviewed on Sep 20, 2026
Where to stay in Santa Croce
Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Duomo
Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.
Santa Maria Novella
Spend some time in an attractive neighborhood close to the city center that encompasses ancient buildings and churches and a large park of outstanding beauty.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Santa Croce Hotel Deals
Plaza Hotel Lucchesi
Lungarno Della Zecca Vecchia 38 Florence FI
Fully refundableReserve now, pay when you stay
$284 nightly
$328 total
Oct 18 - Oct 19
Total with taxes and fees
9.4/10 Exceptional! (1,000 reviews)
"Rooms were small especially the shower. Good location for walking to everything."
Reviewed on Sep 17, 2026
FH55 Grand Hotel Mediterraneo
Lungarno del Tempio, 44 Florence FI
$179 nightly
$213 total
Oct 20 - Oct 21
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
"Great place to stay at."
Reviewed on Sep 15, 2026
LHP Hotel River & SPA
Lungarno Della Zecca Vecchia 18 Florence FI
$306 nightly
$355 total
Oct 11 - Oct 12
Total with taxes and fees
8.8/10 Excellent! (281 reviews)
"The staff was really great. We did the check-in with Costanza, who was very nice, knowledgeable, and welcoming. We felt very comfortable immediately. The room was clean, a bit small and comfortable. The breakfast was really good with many different choices for everyone. We really enjoyed our stay ..."
Reviewed on Sep 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Croce attractions
Piazza Santa Croce
8.8/10 (12 reviews)
Italy’s most famous soccer game takes place here once a year, but the square is better known as a nighttime hangout of choice for young people.
Basilica of Santa Croce
9.2/10 (3,079 reviews)
Glorious tombs mark the resting place of Michelangelo, Galileo and many other Italian greats in the largest Franciscan church in the world.
Teatro Verdi
9.0/10 (2 reviews)
Get tickets for a show at Teatro Verdi, a storied theater in Florence. Discover the acclaimed art scene and notable monuments in this vibrant area.
Church of Sant'Ambrogio
9.0/10 (13 reviews)
After visiting Church of Sant'Ambrogio, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or visit the notable monuments in this vibrant area.
Mercato di Sant'Ambrogio
10.0/10 (1 review)
You can browse for the perfect souvenirs at Mercato di Sant'Ambrogio during your trip to Florence. Discover the fascinating museums and notable monuments in this vibrant area.
National Central Library of Florence
Find out about the history of Florence when you take a trip to National Central Library of Florence. Discover the area's beautiful sunsets and notable monuments.
Casa Buonarroti
8.0/10 (3 reviews)
You can study the exhibits at Casa Buonarroti, a museum with a story of its own, during your trip to Florence. Discover the fascinating museums and stunning cathedral in this vibrant area.
Palazzo dell'Antella
You can find out about the history of Florence with a trip to Palazzo dell'Antella. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
$29
per adult
76% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
$19
per adult
94% of travellers recommend
Accademia timed-entry Ticket with Instant Delivery & Priority Access
$45
per adult
94% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.