Santa Croce Vacations from $1,002

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Your Santa Croce Vacation

Our Santa Croce vacation packages are a fast and practical way to plan and reserve your next adventure. Uncover the true character of this unique neighborhood without the hassle of having to organize everything yourself. Some top nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can put your plans into action. Book your ultimate Santa Croce vacation now.

The Latest Santa Croce Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Price was $1,572, price is now $1,002 per person
$1,002
per person
Sep 1 - Sep 6
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,025 reviews)
The location is excellent. Close to the train station, shops and restaurants. Room was very clean. Breakfast was included. all good.

Reviewed on Jun 19, 2026

Dimora Palanca Boutique & SPA

Dimora Palanca Boutique & SPA

5 out of 5
Historic Centre of Florence
Price was $2,256, price is now $1,435 per person
$1,435
per person
Aug 24 - Aug 28
found 22 hours ago
Roundtrip non-stop flight included
Baltimore (BWI) to Florence (FLR)
9.2/10 Wonderful! (66 reviews)
I particularly love the authenticity of the building being hundreds of hundreds of years old and yet well cut, beautiful staff beautiful spa only lacking in the dining aspect but everything else was perfect. Highly recommend but recommend going out for dinner.

Reviewed on Nov 5, 2025

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

5 out of 5
Historic Centre of Florence
Price was $3,066, price is now $1,953 per person
$1,953
per person
Aug 24 - Aug 28
found 22 hours ago
Roundtrip non-stop flight included
Baltimore (BWI) to Florence (FLR)
10/10 Exceptional! (20 reviews)
Lovely stay. Highly recommend it!

Reviewed on Jun 11, 2026

Aurum Uffizi

Aurum Uffizi

4 out of 5
Historic Centre of Florence
Price was $1,995, price is now $1,280 per person
$1,280
per person
Sep 3 - Sep 8
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,011 reviews)
The hotel was conveniently located, and the service was good. Overall, it was a pleasant stay. However, I hope the hotel improves its Wi-Fi coverage, as the connection can become unstable when multiple guests are accessing the network.

Reviewed on Jun 5, 2026

LHP Certaldo Resort

LHP Certaldo Resort

5 out of 5
Price was $2,209, price is now $1,437 per person
$1,437
per person
Aug 24 - Aug 28
found 22 hours ago
Roundtrip non-stop flight included
Baltimore (BWI) to Florence (FLR)
9.2/10 Wonderful! (532 reviews)
The staff were excellent, especially Carim.

Reviewed on May 10, 2026

Where to stay in Santa Croce

Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Historic Centre of Florence

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Santa Croce Hotel Deals

Plaza Hotel Lucchesi

Plaza Hotel Lucchesi

4 out of 5
Lungarno Della Zecca Vecchia 38 Florence FI
Fully refundableReserve now, pay when you stay
$259 nightly
The price is $301 total per night from Jul 18 to Jul 19
$301 total
Jul 18 - Jul 19
Total with taxes and fees
9.4/10 Exceptional! (1,000 reviews)
"Beautiful property, nice rooftop"

Reviewed on Jun 6, 2026

Plaza Hotel Lucchesi
FH55 Grand Hotel Mediterraneo

FH55 Grand Hotel Mediterraneo

4 out of 5
Lungarno del Tempio, 44 Florence FI
$129 nightly
The price is $157 total per night from Jun 29 to Jun 30
$157 total
Jun 29 - Jun 30
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
"Good location. Well mantained. We took a room with balcony what makes the stay more comfortable. We took breakfast only once because we ordered an omelette and it was not good at all, sometimes it is difficult for non European people because the people in Europe are used to have too much bread and ..."

Reviewed on Jun 18, 2026

FH55 Grand Hotel Mediterraneo
Aurum Uffizi

Aurum Uffizi

4 out of 5
Via Osteria Del Guanto 6 Florence FI
$249 nightly
The price is $290 total per night from Jul 12 to Jul 13
$290 total
Jul 12 - Jul 13
Total with taxes and fees
7.6/10 Good! (1,002 reviews)
"Location was excellent! Highly recommended."

Reviewed on Jun 17, 2026

Aurum Uffizi
See all 891 properties in Santa Croce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Santa Croce

Piazza Santa Croce

Piazza Santa Croce

4/5(5 reviews)

Italy’s most famous soccer game takes place here once a year, but the square is better known as a nighttime hangout of choice for young people.

Piazza Santa Croce
Basilica of Santa Croce

Basilica of Santa Croce

4.5/5(1,001 reviews)

Glorious tombs mark the resting place of Michelangelo, Galileo and many other Italian greats in the largest Franciscan church in the world.

Basilica of Santa Croce

Church of Sant'Ambrogio

4/5(5 reviews)

After visiting Church of Sant'Ambrogio, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.

Church of Sant'Ambrogio

Things to do

City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

$34
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

$23
per adult
82% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
People riding scooters in Tuscany

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine

$129
per adult
100% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.