Santa Mesa Vacations from $1,028

Book a Hotel + Flight or Car together to unlock savings

Photo by Liza Buban-Tantuco

Your Santa Mesa Vacation

Your next escape is calling your name with a vacation package to Santa Mesa. Food, fun and good times — you're bound to find it in this neighborhood. Your trip to Santa Mesa wouldn't be complete without a stop at major attractions nearby such as Rizal Park, Smart Araneta Coliseum and Baywalk. Expedia can help turn your dream Santa Mesa vacation into reality, no matter your travel plans or budget.

The Latest Santa Mesa Vacation Packages

Price found within the past 48 hours. Click for updated prices.
U Hotels Makati
Luxury Staycation beside Okada
Herald Suites Polaris
Playful 1BR Bayview Near Okada & MOA
Prince Plaza II Hotel

Where to stay in Santa Mesa

Find the best Santa Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Santa Mesa

Santa Mesa Hotel Deals

Seda Bonifacio Global City Manila

Seda Bonifacio Global City Manila

4 out of 5
30th Street cor. 11th Avenue Taguig Manila
$120 nightly
The price is $135 total per night from Nov 13 to Nov 14
$135 total
Nov 13 - Nov 14
Total with taxes and fees
Seda Bonifacio Global City Manila
Savoy Hotel Manila near Airport NAIA Terminal 3 MNL

Savoy Hotel Manila near Airport NAIA Terminal 3 MNL

4 out of 5
101 Andrews Avenue, Newport City Pasay Metro Manila
$58 nightly
The price is $66 total per night from Dec 1 to Dec 2
$66 total
Dec 1 - Dec 2
Total with taxes and fees
Savoy Hotel Manila near Airport NAIA Terminal 3 MNL
Dusit Thani Manila

Dusit Thani Manila

5 out of 5
Arnaiz Ave, Ayala Center Makati Manila
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $145 total per night from Dec 6 to Dec 7
$145 total
Dec 6 - Dec 7
Total with taxes and fees
9/10 Wonderful! (2,915 reviews)
"Staff was so polite"

Reviewed on Nov 8, 2026

Dusit Thani Manila
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Mesa attractions

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.