Title: Top 10 Hotels in Santa Rosa from $22 - Competitive Prices | Expedia.com [Santa Rosa Travel Guide](https://expedia.com/Santa-Rosa.dx829297946878021632)[Vacation Rentals in Santa Rosa](https://expedia.com/Santa-Rosa-Vacation-Rentals.d829297946878021632.Travel-Guide-VacationRentals)[Flights to Santa Rosa](https://expedia.com/Cheap-Flights-To-Santa-Rosa.d829297946878021632.Travel-Guide-Flights)[Car Rentals in Santa Rosa](https://expedia.com/Car-Rentals-In-Santa-Rosa.d829297946878021632.Car-Rental-Guide)[Santa Rosa Vacation Packages](https://expedia.com/Santa-Rosa.d829297946878021632.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Rosa Pool [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-29&d2=2026-03-29&amenities=POOL) Family friendly [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-29&d2=2026-03-29&travelerType=family_friendly) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-29&d2=2026-03-29&amenities=PETS) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-29&d2=2026-03-29&amenities=HOT_TUB) Spa [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-29&d2=2026-03-29&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-29&d2=2026-03-29&lodging=APART_HOTEL) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-29&d2=2026-03-29&lodging=APARTMENT) Condo [](https://www.expedia.com/Hotel-Search?destination=Santa+Rosa%2C+Col%C3%B3n%2C+Panama®ionId=829297946878021632&latLong=9.204619%2C-79.678563&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-29&d2=2026-03-29&lodging=CONDO) ## Check prices for these dates Tonight [Mar 13 - Mar 14](https://www.expedia.com/Hotel-Search?regionId=829297946878021632&startDate=2026-03-13&endDate=2026-03-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 14 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=829297946878021632&startDate=2026-03-14&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=829297946878021632&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=829297946878021632&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Rosa hotels ![Food and drink](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/c1dda5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/d12ac1da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/f53158fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/afc6d0da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Panama Metromall [](https://www.expedia.com/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) San Antonio 9.0/10 Wonderful (1,002 reviews) "Staff was good rooms clean just a good experience " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adrian $118 nightly $130 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dc088c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfbf214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites [](https://www.expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Costa del Este 9.4/10 Exceptional (235 reviews) "The stay was wonderful and seamless they are very friendly and efficient as always" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clifford $162 nightly $178 total Mar 14 - Mar 15 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/166e4001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ea9ff933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c579d87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City [](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Juan Diaz 9.6/10 Exceptional (674 reviews) "As usual the stay was amazing in this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose $224 nightly $247 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/616200e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w2560h3836x0y4-b9b31746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/6fa9ba2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w5759h3838x0y0-d4c8ab5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Panama City [](https://www.expedia.com/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) Bella Vista 9.8/10 Exceptional (217 reviews) "Amazing hotel 🏨 " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Camilo Ernesto $164 nightly $181 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/fe3d7092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/dea447f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/93c6a3dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/7b45a441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Panama Canal [](https://www.expedia.com/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) Amador 8.6/10 Excellent (1,017 reviews) "Great ocean view with views of Panama Canal. Wonderful staff and walking trail on Amador Causeway." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck $74 nightly $81 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/23fa73c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/5a498bf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/8d6ae106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed | Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/2fee40c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Panama [](https://www.expedia.com/Panama-City-Hotels-The-Westin-Panama.h5781845.Hotel-Information) Costa del Este 9.0/10 Wonderful (323 reviews) "Clean room, helpful staff, good breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie $206 nightly $226 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-The-Westin-Panama.h5781845.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/4235e7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/d4b0e49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/a2139207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/530000/527200/527169/9e56ccf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Panama City Hotel [](https://www.expedia.com/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information) Bella Vista 8.8/10 Excellent (166 reviews) "Very good hotel, well located. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) AndrĂ©s $127 nightly $140 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Renaissance-Panama-City-Hotel.h527169.Hotel-Information) ![Daily buffet breakfast (PAB 21 per person)](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/c780324d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/22409c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/58ea7ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama [](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) San Francisco 8.6/10 Excellent (1,001 reviews) "Nice convenient placed hotel. Pleasant and very helpful staff. Lovely comfortable place to stay" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Mark $127 nightly $139 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/75c7ddd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![aloft, Suite, 2 Queen Beds, City View | Living room | 42-inch LED TV with digital channels, TV, pay movies](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/8e89de30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/02a8cee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/8c2779b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Panama [](https://www.expedia.com/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information) San Francisco 8.6/10 Excellent (983 reviews) "Very clean room great staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Derenique Shann $112 nightly $123 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed, Partial Ocean View | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/2c21fbc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/08d313d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/w3996h2667x4y0-a167c2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) San Francisco 9.0/10 Wonderful (1,002 reviews) "Beautiful hotel, great service. Breakfast buffet is amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamara $246 nightly $270 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (In the heart of the City) | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/8d82f49a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (In the heart of the City) | City view](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/81e63597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/f2fa3d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Panama [](https://www.expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) Bella Vista 9.0/10 Wonderful (5,076 reviews) "Great breakfast, clean room, friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joy $157 nightly $172 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/123000000/122990000/122982800/122982720/bfe823fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/123000000/122990000/122982800/122982720/52be3704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/123000000/122990000/122982800/122982720/09bfa0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, Garden View | Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/123000000/122990000/122982800/122982720/ebafbcf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modal [](https://www.expedia.com/Panama-City-Hotels-Modal.h122982720.Hotel-Information) Panama City 9.0/10 Wonderful (2 reviews) "First of all, Expedia has it advertised as 10 minute walk or 3 minutes from airport. Far from the truth. 17km and 35 minutes 3 tolls away. No sign anywhere on the building and very dark at night. Our Uber driver could not find it neither. We finally got out and asked. Everything is modernized. Had to find the Email to find passcodes to enter. Found a women once we entered and wanted to know how we got in. 20 minutes later and in my junk mail. The building is new, everything clean. Everything!... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose $59 nightly $66 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Modal.h122982720.Hotel-Information) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/94455d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/094aef75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/c826c327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Plaza by Wyndham Panama Punta Pacifica [](https://www.expedia.com/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) San Francisco 9.6/10 Exceptional (1,165 reviews) "Always my hotel in Panama. Good location great staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nizar $115 nightly $126 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![2 bars/lounges, gastropub](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/f3b8e5d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/6db7ada6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/d27e0b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, gastropub](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/8e100c2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Urban Hotel [](https://www.expedia.com/Panama-City-Hotels-Riande-Urban-Hotel.h185277.Hotel-Information) Bella Vista 8.8/10 Excellent (1,046 reviews) "The hotel is amazing, friendly staff." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) ROBERTO ENRIQUE $84 nightly $93 total Mar 14 - Mar 15 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Riande-Urban-Hotel.h185277.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/194428d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 Queen Bed | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/a0d45136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Double Beds | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/8ab07dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, garden views ](https://images.trvl-media.com/lodging/2000000/1420000/1410100/1410051/fa98dd9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Albrook Inn [](https://www.expedia.com/Panama-City-Hotels-Albrook-Inn.h1410051.Hotel-Information) Panama City 7.8/10 Good (589 reviews) "Friendly front desk staff, comfortable bed, close proximity to airport" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hildi $63 nightly $70 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Albrook-Inn.h1410051.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/6ae0cc51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/2e6f2507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/8c9eeca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/34e202d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Felipe [](https://www.expedia.com/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) Casco Viejo 9.4/10 Exceptional (322 reviews) "I really enjoyed my stay here. The location was great and the staff is outstanding. " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Michael $121 nightly $133 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518500/518415/e50f0da8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/520000/518500/518415/258774a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518415/ae98d4e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave (Living Room;with Sofabed) | Premium bedding, down comforters, Select Comfort beds, in-room safe](https://images.trvl-media.com/lodging/1000000/520000/518500/518415/17db5548.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western El Dorado Panama Hotel [](https://www.expedia.com/Panama-City-Hotels-Best-Western-El-Dorado-Panama-Hotel.h518415.Hotel-Information) Bethania 9.0/10 Wonderful (676 reviews) "Staff super nice as always. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather $90 nightly $99 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Best-Western-El-Dorado-Panama-Hotel.h518415.Hotel-Information) ![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/7bb8f38a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/860def94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Panama Hotel [](https://www.expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) Panama City 9.0/10 Wonderful (1,000 reviews) "Good room, good breakfast, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bret $161 nightly $177 total Apr 10 - Apr 11 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/91ac7bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/4ac2734a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/3db8be94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, individually furnished](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/05c7fc0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza Paitilla Inn Hotel [](https://www.expedia.com/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) San Francisco 9.4/10 Exceptional (2,118 reviews) "excellent value for the money with a very good breakfast buffet" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Gary $108 nightly $119 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Superior Suite Duplex, Balcony, Sea View | In-room safe, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/83c9df4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Duplex, Balcony, City View | Living area](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/c880798a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/1dd7c6ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119740000/119739400/119739302/14d9a23b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bardot Boutique [](https://www.expedia.com/Panama-City-Hotels-Hotel-Bardot-Boutique.h119739302.Hotel-Information) Casco Viejo 9.0/10 Wonderful (10 reviews) "What a special place! Very reasonable rate for an amazing location. 2 level suite was sweet! Love the decor. The staff and restuarant/bar is magnificent in every way!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveler $113 nightly $126 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Panama-City-Hotels-Hotel-Bardot-Boutique.h119739302.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-27&endDate=2026-03-28®ionId=829297946878021632&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_829297946878021632) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Rosa-Hotels.d829297946878021632.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Rosa-Hotels.d829297946878021632.Travel-Guide-Hotels) ## Top Santa Rosa Hotel Reviews ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/a1c4d702_y.jpg) ### Waymore Hotel Spa & Casino 8/10 Good "Great quiet hotel. Pool a decent size and never crowded. No nice relaxing evening bar was the only disadvantage. Metro near. Good room. Would stay again. " [](https://expedia.com/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Hotel was very clean and staff was very kind " [](https://expedia.com/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Very enjoyable stay" [](https://expedia.com/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "It was an excellent area overall for staying. " [](https://expedia.com/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Aloft Panama](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/75c7ddd0_y.jpg) ### Aloft Panama 10/10 Excellent "Great stay Staff was great Rooms need drawers weird???? Restaurant staff at Aloft great Horrible at neighboring Hotel Sheraton “awful” Walked out 3 times!!!!" [](https://expedia.com/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "Yes" [](https://expedia.com/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 6/10 Okay "The hotel was fine. The hallway on the 19th floor had a weird odor, which I believe hotel was aware of because an air purifier was always there. One could hardly sleep most nights due to the guests in the end room next to us. They had booming music that woke us up, with altercations and door slamming throughout the nights during our stay. " [](https://expedia.com/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/bd4cfae6_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Excellent hotel, staff, and re" [](https://expedia.com/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7_y.jpg) ### The Executive Hotel 10/10 Excellent "Great stay overall. Attentive staff, great breakfast, extremely clean rooms. Great free parking. Would stay again for sure. " [](https://expedia.com/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ## More cheap stays in Santa Rosa ![HOTEL SAN THOMAS INN](https://images.trvl-media.com/lodging/102000000/101070000/101069500/101069427/6ca70005_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL SAN THOMAS INN AVE. JUSTO AROSEMENA, CALLE 33 Panama City $21 nightly $23 total Mar 26 - Mar 27 Total with taxes and fees 6.4/10 (56 reviews) [](https://expedia.com/Panama-City-Hotels-HOTEL-SAN-THOMAS-INN.h101069427.Hotel-Information) ![Hotel RepĂşblica](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/77400971_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel RepĂşblica Plaza 5 De Mayo Final Ave Panama City Panama $23 nightly $26 total Mar 26 - Mar 27 Total with taxes and fees 6.6/10 (187 reviews) [](https://expedia.com/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ![Panama House Bed & Breakfast](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/bf18b63d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Panama House Bed & Breakfast Calle 1era El Carmen- Casa # 32 Panama City $34 nightly $38 total Mar 16 - Mar 17 Total with taxes and fees 9/10 Wonderful! (196 reviews) [](https://expedia.com/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) ![Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals](https://images.trvl-media.com/lodging/60000000/59270000/59264500/59264464/b5e8c48b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals Avenida Peru Y Calle 30 Panama City Panama Province $66 nightly $72 total Mar 16 - Mar 17 Total with taxes and fees 7.6/10 Good! (218 reviews) [](https://expedia.com/Panama-City-Hotels-Veracruz-Hotel.h59264464.Hotel-Information) ![Magnolia Inn](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/60cd745e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Magnolia Inn 8-18 Calle 8 y Calle Boquete Panama City Panama $119 nightly $131 total Mar 16 - Mar 17 Total with taxes and fees 8.8/10 Excellent! (456 reviews) [](https://expedia.com/Panama-City-Hotels-Magnolia-Inn.h24165406.Hotel-Information) ![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Arcadia Condo Suites Calle rio mar Panama City Panamá Province $162 nightly $178 total Mar 14 - Mar 15 Total with taxes and fees 9.4/10 Exceptional! (235 reviews) [](https://expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ## Hotels in Santa Rosa with star-rating ![5 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/25600/25559/c6e0103a_z.jpg) 5 Star Hotels 11 properties [](https://expedia.com/5Star-Santa-Rosa-Hotels.s50-0-d829297946878021632.Travel-Guide-Filter-Hotels) ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 75 properties [](https://expedia.com/4Star-Santa-Rosa-Hotels.s40-0-d829297946878021632.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 234 properties [](https://expedia.com/3Star-Santa-Rosa-Hotels.s30-0-d829297946878021632.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 434 properties [](https://expedia.com/2Star-Santa-Rosa-Hotels.s20-0-d829297946878021632.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Santa Rosa? > This area is the heart of Santa Rosa, offering a convenient base for exploring the city. You'll find a concentration of local businesses, dining options, and access to public transportation. The Parque Central is a key landmark, providing a central gathering spot. > > > For travelers who appreciate convenience and easy access to local amenities, staying in the city center is ideal. ### When is the best time to go to Santa Rosa? > During these months, you'll experience sunny days with lower humidity and minimal rainfall, making it ideal for outdoor activities like hiking, wildlife viewing, and enjoying the beaches. The clearer skies also provide better conditions for photography and sightseeing. > > > Travelers looking for a relaxed and pleasant experience will find this time particularly suitable. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Rosa hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Santa Rosa hotel? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app