Default HTG hotel image

Find hotels in Santa Rosa

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Star rating

Our top choices for Santa Rosa hotels

Arcadia Condo Suites

Arcadia Condo Suites
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (305 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
$132 nightly
The price is $145
Jun 22 - Jun 23
Total with taxes and fees
Arcadia Condo Suites

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
Colon
8.0 out of 10, Very Good, (776 reviews)
"Great place to stay."
United States
Oscar
$132 nightly
The price is $145
Jun 29 - Jun 30
Total with taxes and fees
Gamboa Rainforest Reserve

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (231 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
$127 nightly
The price is $140
Jun 28 - Jun 29
Total with taxes and fees
Renaissance Panama City Hotel

Hotel Andros

Hotel Andros
3.0 star property
Barrio Sur
8.0 out of 10, Very Good, (165 reviews)
"Excelente "
Mexico
Jairo
$34 nightly
The price is $38
Jun 30 - Jul 1
Total with taxes and fees
Hotel Andros

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,001 reviews)
"The breakfast was very good. We love staying here"
United States
Patricia
$86 nightly
The price is $94
Jun 28 - Jun 29
Total with taxes and fees
Radisson Hotel Panama Canal

SAND DIAMOND HOTEL

SAND DIAMOND HOTEL
3.0 star property
Colon
8.6 out of 10, Excellent, (270 reviews)
"Hotel was a perfect location "
United States
Ari
$116 nightly
The price is $128
Jun 23 - Jun 24
Total with taxes and fees
SAND DIAMOND HOTEL

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,002 reviews)
"Solid property with excellent staff."
United States
Craig
$132 nightly
The price is $145
Jul 4 - Jul 5
Total with taxes and fees
Sheraton Grand Panama

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,003 reviews)
"The stay was amazing"
United States
Desmond
$109 nightly
The price is $120
Jul 19 - Jul 20
Total with taxes and fees
Courtyard by Marriott Panama Metromall

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,618 reviews)
"Great Location, good food."
United States
Yohan
$147 nightly
The price is $162
Jun 29 - Jun 30
Total with taxes and fees
Hotel Riu Plaza Panama

Hotel San Felipe

Hotel San Felipe
4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (403 reviews)
"The location is excellent!"
United States
Christine
$120 nightly
The price is $132
Jun 24 - Jun 25
Total with taxes and fees
Hotel San Felipe

Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
3.0 star property
Bethania
9.0 out of 10, Wonderful, (727 reviews)
"Great hotel for family visit"
United States
ZULEMA MARTA PHUN
$90 nightly
The price is $99
Jun 22 - Jun 23
Total with taxes and fees
Best Western El Dorado Panama Hotel

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1,003 reviews)
"Our stay was great ! Definitely worth staying here 👍"
United States
CODY
$174 nightly
The price is $192
Jul 15 - Jul 16
Total with taxes and fees
Central Hotel Panama Casco Viejo

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (972 reviews)
"I would stay here again rooms where very clean"
United States
nicole
$115 nightly
The price is $127
Jun 22 - Jun 23
Total with taxes and fees
Waymore Hotel Spa & Casino

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (703 reviews)
"Stunning ! Beautiful Hotel ! Excelent Service Delicious Food Luxury modern room Can’t wait to go back ! Love it so much !"
United States
Marina
$269 nightly
The price is $296
Jul 2 - Jul 3
Total with taxes and fees
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Summit Rainforest Golf Resort & All Inclusive

Summit Rainforest Golf Resort & All Inclusive
4.0 star property
Panama City
8.4 out of 10, Very Good, (1,001 reviews)
"Excellent location and clean hotel"
United States
Mark
$215 nightly
The price is $236
Jun 22 - Jun 23
Total with taxes and fees
Summit Rainforest Golf Resort & All Inclusive

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,568 reviews)
"I love my stay, very convenient for everything, shopping, close by red bus stop and airport!!!"
United States
Carla
$131 nightly
The price is $145
Jul 19 - Jul 20
Total with taxes and fees
Megapolis Hotel Panamá

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (346 reviews)
"Great stay! We enjoyed the hospitality!"
United States
Craig
$214 nightly
The price is $235
Jun 28 - Jun 29
Total with taxes and fees
Hyatt Regency Panama City

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
4.0 star property
Barrio Sur
8.2 out of 10, Very Good, (942 reviews)
"Excellent location prior to boarding cruise! "
United States
Valarie
$116 nightly
The price is $128
Jul 5 - Jul 6
Total with taxes and fees
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

Hotel Bardot Boutique

Hotel Bardot Boutique
3.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (33 reviews)
"Excellent location in the most tourist part of Panama City, Casco Antiguo. Safe area, local to everything, and a beautiful hotel. "
United States
Fatin
$110 nightly
The price is $122
Jul 12 - Jul 13
Total with taxes and fees
Hotel Bardot Boutique

La Cubana Hotel & Residencial

La Cubana Hotel & Residencial
2.5 star property
Cristobal
8.4 out of 10, Very Good, (128 reviews)
"The price reflects the area where it is located, the room was clean and well maintained. Appreciated the ability to check in early without extra cost. "
Canada
Clara
$30 nightly
The price is $33
Jun 27 - Jun 28
Total with taxes and fees
La Cubana Hotel & Residencial
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Rosa Hotel Reviews

Frequently asked questions

What is the best area to stay in Santa Rosa?
The best area to stay in Santa Rosa for most travelers is the city center, particularly around Avenida Central and the Parque Central.

This area is the heart of Santa Rosa, offering a convenient base for exploring the city. You'll find a concentration of local businesses, dining options, and access to public transportation. The Parque Central is a key landmark, providing a central gathering spot.

For travelers who appreciate convenience and easy access to local amenities, staying in the city center is ideal.
When is the best time to go to Santa Rosa?
The best time to visit Santa Rosa, Colón, Panama, is during the dry season, which runs from mid-December to mid-April. This period offers the most comfortable weather for exploring.

During these months, you'll experience sunny days with lower humidity and minimal rainfall, making it ideal for outdoor activities like hiking, wildlife viewing, and enjoying the beaches. The clearer skies also provide better conditions for photography and sightseeing.

Travelers looking for a relaxed and pleasant experience will find this time particularly suitable.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Rosa.
How can I save on a Santa Rosa hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santa Rosa hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Rosa hotel?
Prices for hotels in Santa Rosa often vary, but you can find a great deal on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.