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Our top choices for Santa Rosa hotels

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (283 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
$165 nightly
The price is $181
May 10 - May 11
Total with taxes and fees
Arcadia Condo Suites

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,006 reviews)
"Great service, very comfortable beds, truly excellent breakfast manager and staff. "
United States
Elizabeth
$93 nightly
The price is $102
May 23 - May 24
Total with taxes and fees
Courtyard by Marriott Panama Metromall

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,392 reviews)
"Very nice clean spacious rooms with great breakfast!"
United States
Petronella
$121 nightly
The price is $133
May 26 - May 27
Total with taxes and fees
Hotel Riu Plaza Panama

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (693 reviews)
"Breakfast was exceptional, everything you could think of was available. The spa was great and the staff 10/10"
United States
Aeon
$247 nightly
The price is $271
May 15 - May 16
Total with taxes and fees
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Panama Canal Inn

Panama Canal Inn
3.0 star property
Panama City
8.2 out of 10, Very Good, (20 reviews)
"Excellent hotel, good location, nice stay and great service."
United States
Rocio Hernandez
$50 nightly
The price is $55
May 15 - May 16
Total with taxes and fees
Panama Canal Inn

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,011 reviews)
"The staff were excellent!"
United States
James
$134 nightly
The price is $148
May 15 - May 16
Total with taxes and fees
Sheraton Grand Panama

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (294 reviews)
"Clean great food transportation to everything was close"
United States
celso
$153 nightly
The price is $168
May 31 - Jun 1
Total with taxes and fees
Hyatt Regency Panama City

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (332 reviews)
"Excellent stay, friendly and attentive staff, beautiful property!!!"
United States
Erica
$223 nightly
The price is $245
Jun 6 - Jun 7
Total with taxes and fees
The Westin Panama

Hotel Bardot Boutique

Hotel Bardot Boutique
3.0 star property
Casco Viejo
9.6 out of 10, Exceptional, (24 reviews)
"Excellent location in the most tourist part of Panama City, Casco Antiguo. Safe area, local to everything, and a beautiful hotel. "
United States
Fatin
$113 nightly
The price is $125
May 13 - May 14
Total with taxes and fees
Hotel Bardot Boutique

Serenade Lodging Rooms

Serenade Lodging Rooms
3.0 star property
San Francisco
8.6 out of 10, Excellent, (24 reviews)
"Nice affordable place. "
United States
Sandor
$53 nightly
The price is $59
May 7 - May 8
Total with taxes and fees
Serenade Lodging Rooms

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (208 reviews)
"Clean room and staff very friendly."
United States
Patricia
$127 nightly
The price is $140
May 13 - May 14
Total with taxes and fees
Renaissance Panama City Hotel

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,181 reviews)
"Clean room, very helpful staff and great breakfast."
United States
Emmanuela
$100 nightly
The price is $110
May 25 - May 26
Total with taxes and fees
Ramada Plaza by Wyndham Panama Punta Pacifica

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,013 reviews)
"Very nice and safe place to stay"
United States
Nilesh
$255 nightly
The price is $281
Jun 6 - Jun 7
Total with taxes and fees
JW Marriott Panama

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,004 reviews)
"Good hotel, great pool, great location, full breakfast. "
Canada
Byron
$74 nightly
The price is $81
May 13 - May 14
Total with taxes and fees
Radisson Hotel Panama Canal

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (898 reviews)
"Great place and good location. "
United States
Edward
$91 nightly
The price is $100
May 13 - May 14
Total with taxes and fees
Waymore Hotel Spa & Casino

Albrook Inn

Albrook Inn
3.0 star property
Panama City
7.8 out of 10, Good, (604 reviews)
"Awesome place near the airport. Clean great breakfast and also a pool. Beauty one night stop!"
Canada
Richard J
$58 nightly
The price is $64
May 10 - May 11
Total with taxes and fees
Albrook Inn

Modal

Modal
2.0 star property
Panama City
9.4 out of 10, Exceptional, (3 reviews)
"First of all, Expedia has it advertised as 10 minute walk or 3 minutes from airport. Far from the truth. 17km and 35 minutes 3 tolls away. No sign anywhere on the building and very dark at night. Our Uber driver could not find it neither. We finally got out and asked. Everything is modernized. Had to find the Email to find passcodes to enter. Found a women once we entered and wanted to know how we got in. 20 minutes later and in my junk mail. The building is new, everything clean. Everything!...
United States
Jose
$75 nightly
The price is $83
May 7 - May 8
Total with taxes and fees
Modal

Oasis Hotel

Oasis Hotel
3.0 star property
Casco Viejo
8.4 out of 10, Very Good, (134 reviews)
"the hotel was great, great location, Claudia very corteous and helpful "
United States
MARGARET
$55 nightly
The price is $61
May 27 - May 28
Total with taxes and fees
Oasis Hotel

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1,002 reviews)
"Everything was excellent on this visit...we were warmly welcomed by the staff."
United States
Mitzie
$161 nightly
The price is $177
May 23 - May 24
Total with taxes and fees
Marriott Panama Hotel

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (645 reviews)
"Had a lovely stay"
United States
Olly
$302 nightly
The price is $332
Jun 5 - Jun 6
Total with taxes and fees
Sofitel Legend Casco Viejo, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is the best area to stay in Santa Rosa?
The best area to stay in Santa Rosa for most travelers is the city center, particularly around Avenida Central and the Parque Central.

This area is the heart of Santa Rosa, offering a convenient base for exploring the city. You'll find a concentration of local businesses, dining options, and access to public transportation. The Parque Central is a key landmark, providing a central gathering spot.

For travelers who appreciate convenience and easy access to local amenities, staying in the city center is ideal.
When is the best time to go to Santa Rosa?
The best time to visit Santa Rosa, Colón, Panama, is during the dry season, which runs from mid-December to mid-April. This period offers the most comfortable weather for exploring.

During these months, you'll experience sunny days with lower humidity and minimal rainfall, making it ideal for outdoor activities like hiking, wildlife viewing, and enjoying the beaches. The clearer skies also provide better conditions for photography and sightseeing.

Travelers looking for a relaxed and pleasant experience will find this time particularly suitable.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Rosa.
How can I save on a Santa Rosa hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santa Rosa hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Rosa hotel?
Prices for hotels in Santa Rosa often vary, but you can find a great deal from $22 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.