Title: Visit Santa Rosa: 2026 Travel Guide for Santa Rosa, Colón | Expedia.com [Hotels in Santa Rosa](https://expedia.com/Santa-Rosa-Hotels.d829297946878021632.Travel-Guide-Hotels)[Vacation Rentals in Santa Rosa](https://expedia.com/Santa-Rosa-Vacation-Rentals.d829297946878021632.Travel-Guide-VacationRentals)[Flights to Santa Rosa](https://expedia.com/Cheap-Flights-To-Santa-Rosa.d829297946878021632.Travel-Guide-Flights)[Car Rentals in Santa Rosa](https://expedia.com/Car-Rentals-In-Santa-Rosa.d829297946878021632.Car-Rental-Guide)[Santa Rosa Vacation Packages](https://expedia.com/Santa-Rosa.d829297946878021632.Destination-Travel-Guides) # Santa Rosa ## Travel Guide ## Visit Santa Rosa ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_829297946878021632) - Santa Rosa Hotel Deals - Vacation Rentals in Santa Rosa ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Riu Plaza Panama Calle 50, Urb. Marbella Panama City Panama $147 nightly $162 total Mar 30 - Mar 31 Total with taxes and fees Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ... 9/10 Wonderful! (5,080 reviews) Renaldo at the breakfast buffet was excellent he made our breakfast wonderful Reviewed on Mar 7, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F30%2F2026&endDate=3%2F31%2F2026&selected=3900395&PinnedHotelID=3900395&HadPinnedHotel=true®ionId=829297946878021632) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sheraton Grand Panama Via Israel And 77th Street Panama City Panama $134 nightly $148 total Apr 3 - Apr 4 Total with taxes and fees Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ... 8.6/10 Excellent! (1,005 reviews) Multiplaza mall very close by Reviewed on Mar 5, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F3%2F2026&endDate=4%2F4%2F2026&selected=1161&PinnedHotelID=1161&HadPinnedHotel=true®ionId=829297946878021632) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### W Panama Calle Aquilino de la Guardia & Calle 50 Panama City $199 nightly $219 total Mar 31 - Apr 1 Total with taxes and fees Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ... 9/10 Wonderful! (1,014 reviews) Staff not friendly Reviewed on Mar 6, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F31%2F2026&endDate=4%2F1%2F2026&selected=21314035&PinnedHotelID=21314035&HadPinnedHotel=true®ionId=829297946878021632) [See all 1,541 properties in Santa Rosa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=829297946878021632) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Arcadia Condo Suites Calle rio mar Panama City Panamá Province Stay at this aparthotel in Panama City. Enjoy free WiFi, free parking, and a rooftop terrace. Popular attractions Multiplaza Pacific Mall and Avenida Balboa ... 9.4/10 Exceptional! (233 reviews) I absolutely love this place. I’ve stayed in two different apartments here so far, and I already have another two-week booking scheduled for next month. That alone says everything. I have not had any issues at all during my stays. Each unit has been super clean and well maintained. The facilities ... Reviewed on Mar 4, 2026 [](https://expedia.com/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Marriott Executive Apartments Panama City, Finisterre](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/b4d43ebd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Marriott Executive Apartments Panama City, Finisterre Calle Colombia Y Ave.,3ra A Sur, Bella V Panama City Panama Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ... 8.8/10 Excellent! (696 reviews) On checking day, we arrived around 7pm on Saturday. It was national holiday and carnival for 4 days in Panama City, Panamá. Jonathan, the receptionist, stated that the hotel is fully occupied even though we had a fully paid reservation for 17 nights . He apologized and asked us to stay in another ... Reviewed on Mar 5, 2026 [](https://expedia.com/Panama-City-Hotels-Marriott-Executive-Apartments-Panama-City.h4958983.Hotel-Information) ![Torres de Alba Hotel & Suites](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1012405e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Torres de Alba Hotel & Suites Calle Eusebio A. Morales y Calle 55 Panama City Panama Book a stay at this business-friendly aparthotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ... 8.8/10 Excellent! (512 reviews) Very nice hotel, shops nearby, clean, rooms are very comfortable includes a living room area, kitchen with utensils and a washer/dryer Reviewed on Mar 3, 2026 [](https://expedia.com/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) [See all properties in Santa Rosa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=829297946878021632&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Rosa hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297946878021632&startDate=2026-03-07&endDate=2026-03-08)[Mar 7 - Mar 8](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297946878021632&startDate=2026-03-07&endDate=2026-03-08) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297946878021632&startDate=2026-03-08&endDate=2026-03-09)[Mar 8 - Mar 9](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297946878021632&startDate=2026-03-08&endDate=2026-03-09) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297946878021632&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026)[Mar 13 - Mar 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=829297946878021632&startDate=3%2F13%2F2026&endDate=3%2F15%2F2026) ## Cities near Santa Rosa ![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Panama City ![Protected nature surrounding Gatun Lake, a freshwater artificial lake to the south of Colón, Panama. It forms a major part of the Panama Canal](https://images.trvl-media.com/place/601867/0f4b2986-19e2-41b5-93da-ec0bc70c4cc2.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Colon ![Panama canal](https://images.trvl-media.com/place/6245737/7da344da-6502-4576-9683-bc1f17970e07.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Chilibre ![Adobe](https://images.trvl-media.com/place/553248635921431980/08f3117c-1641-4cbd-a4d6-07c2d5757057.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Ancon - Cities near Santa Rosa - Places of interest [Panama City](https://expedia.com/Panama-City.dx2897)[Colon](https://expedia.com/Colon.dx601867)[Chilibre](https://expedia.com/Chilibre.dx6245737)[Ancon](https://expedia.com/Ancon.dx553248635921431980)[San Juan](https://expedia.com/San-Juan.dx829297950514503680)[Buena Vista](https://expedia.com/Buena-Vista.dx829297953834291200) - [Albrook Shopping Mall ](https://expedia.com/Albrook-Shopping-Mall-Panama-City.d6159851.Vacation-Attraction) - [Multiplaza Pacific Mall ](https://expedia.com/Multiplaza-Pacific-Mall-San-Francisco.d6158227.Vacation-Attraction) - [Avenida Balboa ](https://expedia.com/Avenida-Balboa-Calidonia.d553248623453290531.Vacation-Attraction) - [Cinta Costera ](https://expedia.com/Cinta-Costera-Calidonia.d6245970.Vacation-Attraction) - [Via Espana ](https://expedia.com/Via-Espana-Bella-Vista.d6125940.Vacation-Attraction) - [Amador Causeway ](https://expedia.com/Amador-Causeway-Amador.d6286127.Vacation-Attraction) - [Colon Free Zone ](https://expedia.com/Colon-Free-Zone-Barrio-Sur.d6078503.Vacation-Attraction) - [El Dorado Mall ](https://expedia.com/El-Dorado-Mall-Bethania.d553248621532963614.Vacation-Attraction) - [Veracruz Beach ](https://expedia.com/Veracruz-Beach-Panama-Oeste-Province.d553248621562725884.Vacation-Attraction) - [Miraflores Locks ](https://expedia.com/Miraflores-Locks-Panama-City.d6078505.Vacation-Attraction) - [Colon 2000 ](https://expedia.com/Colon-2000-Barrio-Sur.d6286212.Vacation-Attraction) - [Panama Viejo ](https://expedia.com/Panama-Viejo-Parque-Lefevre.d6285192.Vacation-Attraction) - [Gamboa Rainforest Resort ](https://expedia.com/Gamboa-Rainforest-Resort-Colon.d6078513.Vacation-Attraction) - [Metromall Panama ](https://expedia.com/Metromall-Panama-Rufina-Alfaro.d6158234.Vacation-Attraction) - [Los Pueblos Commercial Center ](https://expedia.com/Los-Pueblos-Commercial-Center-Juan-Diaz.d6158237.Vacation-Attraction) - [Calle 50 ](https://expedia.com/Calle-50-Bella-Vista.d782156551080820736.Vacation-Attraction) - [Amador Convention Center ](https://expedia.com/Amador-Convention-Center-Amador.d553248635976809818.Vacation-Attraction) - [ATLAPA Conventions Center ](https://expedia.com/ATLAPA-Conventions-Center-San-Francisco.d6286123.Vacation-Attraction) - [Uruguay Street ](https://expedia.com/Uruguay-Street-Bella-Vista.d6294103.Vacation-Attraction) - [Panama Canal Railway ](https://expedia.com/Panama-Canal-Railway-Panama-City.d553248621532619522.Vacation-Attraction) - [Iglesia del Carmen ](https://expedia.com/Iglesia-Del-Carmen-Bella-Vista.d553248634285189314.Vacation-Attraction) - [Metropolitan Cathedral of Panama ](https://expedia.com/Metropolitan-Cathedral-Of-Panama-Casco-Viejo.d6078477.Vacation-Attraction) - [Megapolis Convention Center ](https://expedia.com/Megapolis-Convention-Center-Bella-Vista.d553248634285187604.Vacation-Attraction) - [Crown Casino ](https://expedia.com/Crown-Casino-Bella-Vista.d6159855.Vacation-Attraction) - [Estadio Rommel Fernandez ](https://expedia.com/Estadio-Rommel-Fernandez-Juan-Diaz.d6078481.Vacation-Attraction) - [Panama Canal Murals ](https://expedia.com/Panama-Canal-Murals-San-Francisco.d553248621532965255.Vacation-Attraction) - [Chagres National Park ](https://expedia.com/Chagres-National-Park-Panama.d6252818.Vacation-Attraction) - [Bridge of the Americas ](https://expedia.com/Bridge-Of-The-Americas-Arraijan.d6078487.Vacation-Attraction) - [Multicentro Panama ](https://expedia.com/Multicentro-Panama-San-Francisco.d6158230.Vacation-Attraction) - [Pacific Center ](https://expedia.com/Pacific-Center-San-Francisco.d633625826652135424.Vacation-Attraction) - [Hospital Punta Pacífica ](https://expedia.com/Hospital-Punta-Pacifica-San-Francisco.d553248635976653100.Vacation-Attraction) - [Avenida Central ](https://expedia.com/Avenida-Central-Calidonia.d553248634285194371.Vacation-Attraction)