Santa Rosa Vacations from $657
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The Latest Santa Rosa vacation packages
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
$1,175
per person
Dec 4 - Dec 11
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (1,012 reviews)
Such a great experience! I’d recommend it to anyone and love to stay again.
Reviewed on Sep 20, 2026
Megapolis Hotel Panamá
San Francisco
$876
per person
Dec 3 - Dec 7
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.4/10 Very Good! (1,693 reviews)
Deben mejorar el servicio de atención de parte de su personal de recepción y desayuno
Reviewed on Sep 21, 2026
Hotel Casa Panamá
Casco Viejo
$821
per person
Dec 4 - Dec 11
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
7.6/10 Good! (746 reviews)
Overall a good place to stay for exploring Panama. Lots of restaurants and activities walking distance.
Reviewed on Sep 16, 2026
Santa Rosa Hotel Deals
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$138 nightly
$151 total
Sep 28 - Sep 29
Total with taxes and fees
9/10 Wonderful! (5,974 reviews)
"Excellent"
Reviewed on Sep 22, 2026
Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
$183 nightly
$202 total
Oct 21 - Oct 22
Total with taxes and fees
9/10 Wonderful! (1,007 reviews)
"Such a great experience! I’d recommend it to anyone and love to stay again."
Reviewed on Sep 20, 2026
Megapolis Hotel Panamá
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
$138 nightly
$138 total
Sep 28 - Sep 29
Total with taxes and fees
8.6/10 Excellent! (1,743 reviews)
"Deben mejorar el servicio de atención de parte de su personal de recepción y desayuno"
Reviewed on Sep 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions
How to find the best Santa Rosa package deals?
Use Expedia's handy filters to find some great Santa Rosa package deals. When you start your search, simply set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your trip for midweek, or search for Santa Rosa package deals in the low season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's typically best to book your vacation package as soon as possible.
When to book a vacation package to Santa Rosa?
Score incredible discounts by booking your flights in advance with Expedia. If being spontaneous is more your thing, grab one of our last-minute deals for an impromptu Santa Rosa vacation.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.