Santana Vacations from $355

Book a Hotel + Flight or Car together to unlock savings

Your Santana Vacation

Book a Santana vacation package and get set for a fantastic adventure. Well known for its beaches and cultural experiences, there's tons to love about this captivating city. A trip to Santana is a terrific opportunity to do a bit of sightseeing. Be sure to visit renowned attractions like Cueva Ventana, Arecibo Lighthouse and La Poza Beach. Whatever your travel plans or budget, organizing your ultimate tailored Santana vacation is simple with Expedia.

The Latest Santana vacation packages

Price found within the past 48 hours. Click for updated prices.
Juliette Hostel for Women Only

Juliette Hostel for Women Only

2 out of 5
San Juan Antiguo
Save 100% on your flight
per person
Oct 16 - Oct 22
found 21 hours ago
Roundtrip non-stop flight included
Boston (BOS) to San Juan (SJU)
9.2/10 Wonderful! (67 reviews)
Juliette Hostal has potential, but cleanliness could be improved. When I stayed, there were a lot of young ladies, and it felt like there was drama and tension in the place. I understand guests enjoy going out, but quiet hours should be enforced so everyone can rest. Convenient location, but it didn’t really feel like Puerto Rico’s culture in the establishement.

Reviewed on Aug 10, 2025

San Agustin Apartments

San Agustin Apartments

3 out of 5
San Juan Antiguo
Save 100% on your flight
per person
Oct 18 - Oct 25
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9.2/10 Wonderful! (370 reviews)
Worked with me on short notice! Nice property! Great communication! Amazing hosts!

Reviewed on Aug 16, 2025

Urbana Hotel

Urbana Hotel

2 out of 5
San Juan Antiguo
Save 100% on your flight
per person
Oct 18 - Oct 25
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
8.6/10 Excellent! (317 reviews)
Is there any way i can get a refund since i checked out a day earlier

Reviewed on Aug 16, 2025

The Oliver Hotel

The Oliver Hotel

3 out of 5
San Juan Antiguo
Save 100% on your flight
per person
Oct 18 - Oct 25
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9/10 Wonderful! (32 reviews)
El hotel por dentro es muy bonito, el staff amable. Pero, como es nuevo necesitan estar mas al día con el mantenimiento (aires, inodoros, agua caliente, etc). También mejorar el manejo de los empleados de limpieza (debe hacer menos escándalo) y mejorar la comunicación con las personas de mantenimiento (horarios para hacerlo y si hay huéspedes en la habitación o no).

Reviewed on Aug 9, 2025

Lazy Parrot Inn

Lazy Parrot Inn

3 out of 5
Save 100% on your flight
per person
Oct 29 - Nov 4
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Juan (SJU)
9.2/10 Wonderful! (1,001 reviews)
Great location and friendly staff. Beautiful place. We loved.

Reviewed on Aug 14, 2025

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Discover the most popular places to visit in Santana

Great view of the Arecibo Lighthouse

La Poza Beach

Why not spend a carefree afternoon at La Poza Beach during your travels in Jarealito? You can enjoy the restaurants while in the area.

La Poza Beach
Arecibo Observatory which includes an observatory and forest scenes

Arecibo Observatory

This gigantic radio telescope has contributed to scientific discoveries since the 1960s, and has appeared in many movies and television shows.

Arecibo Observatory
Arecibo Light House

Arecibo Lighthouse

You can find out about the history of Islote when you stop by Arecibo Lighthouse. Stroll along the area's beaches or simply enjoy its restaurants.

Arecibo Lighthouse

What to do in Santana

tubing

Tanama River Cave Tubing

$100
per adult
88% of travellers recommend
Tanama River Cave Tubing
Lighthouse and Aquarium Tour in Puerto Rico

Lighthouse and Aquarium Tour in Puerto Rico

$150
per adult
Lighthouse and Aquarium Tour in Puerto Rico
Explore Indigenous Roots with Farm-to-Table Meal and Transport

Explore Indigenous Roots with Farm-to-Table Meal and Transport

$175
per adult
100% of travellers recommend
Explore Indigenous Roots with Farm-to-Table Meal and Transport
See all activities in Santana

Santana Hotel Deals

Arecibo Inn

Arecibo Inn

3 out of 5
Road #2 km 67.2, Barrio Santana, Arecibo
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $96 total per night from Aug 18 to Aug 19
$96 total
Aug 18 - Aug 19
Total includes taxes and fees
7.8/10 Good! (1,000 reviews)
"The places that I wanted to visit were nearby. Lots of eating options. It is a peaceful area."

Reviewed on Aug 12, 2025

Arecibo Inn
Hyatt Place Manati

Hyatt Place Manati

3.5 out of 5
122 Carretera PR-2, Manati
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $165 total per night from Sep 7 to Sep 8
$165 total
Sep 7 - Sep 8
Total includes taxes and fees
9.2/10 Wonderful! (1,000 reviews)
"Love it"

Reviewed on Aug 13, 2025

Hyatt Place Manati
Hotel El Guajataca

Hotel El Guajataca

3.5 out of 5
Carretera 2 Km. 103.8, Barrio Terranova, Quebradillas
$123 nightly
The price is $135 total per night from Aug 20 to Aug 21
$135 total
Aug 20 - Aug 21
Total includes taxes and fees
8.2/10 Very Good! (1,001 reviews)
"The Refrigerator didnt work good , the air conditiner was not working well and the alarm not smoking qet us crasy the frist night also no hot water , and no light. Thats my personal opinion"

Reviewed on Aug 13, 2025

Hotel El Guajataca
See all 414 properties in Santana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Santana vacation package cost?
You can snap up a vacation package to this popular destination from $355 on Expedia. However, how much your vacation to Santana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santana?
You can typically find reduced prices and greater availability in August, September and December. Check out our cheap Santana vacation packages and you could score some great off-season discounts.
How many days is enough for Santana?
With a well-organized travel plan, you can easily tick off the main Santana sights in a few days. But if you prefer to discover hidden spots or go on day trips, think about booking your Santana vacation for longer.
How to find the best Santana package deals?
Finding a cheap Santana package deal is a breeze with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your budget, add a few filters and see what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most affordable Santana package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are usually lower.
Is it cheaper to book a Santana vacation as a package?
An Expedia vacation package could score you significant savings when compared to arranging flights and accommodations separately. Better still, you can customize your Santana escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santana?
Land incredible bargains by booking your flights early with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for an impromptu Santana trip.
Does Expedia offer Book Now, Pay Later Santana vacation packages?
Your Santana break is meant to be an escape from your daily routine, not a source of money-related stress. So to give you more flexibility, we've teamed up with online lender Affirm to offer our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and spread the total cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.