Santana Vacations from $633

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Santana Vacation

Book a Santana vacation package and get set for a fantastic adventure. Well known for its beaches and cultural experiences, there's tons to love about this captivating city. A trip to Santana is a terrific opportunity to do a bit of sightseeing. Be sure to visit renowned attractions like Cueva Ventana, Arecibo Lighthouse and La Poza Beach. Whatever your travel plans or budget, organizing your ultimate tailored Santana vacation is simple with Expedia.

The Latest Santana vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Puerto Valdes
Lazy Parrot Inn
Aire de O:live
Serenity by Otium
Hyatt Vacation Club at Hacienda del Mar, Dorado
Don't see what you're looking for?
See all available trips from Columbus to Santana
View all trips

Discover the most popular places to visit in Santana

What to do in Santana

Santana Hotel Deals

Arecibo Inn

Arecibo Inn

3 out of 5
Road #2 km 67.2 Arecibo
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $111 total per night from Mar 30 to Mar 31
$111 total
Mar 30 - Mar 31
Total with taxes and fees
8/10 Very Good! (1,001 reviews)
The breakfast was a joke,the room they did not cleaned they claim that the do not disturb sign was on which was not 3out 5 was not cleaned.Ac was difficult to adjust. I took pictures which I will post soon.

Reviewed on Mar 27, 2026

Arecibo Inn
Hyatt Place Manati

Hyatt Place Manati

3.5 out of 5
122 Carretera PR-2 Manati
Fully refundableReserve now, pay when you stay
$256 nightly
The price is $284 total per night from Apr 5 to Apr 6
$284 total
Apr 5 - Apr 6
Total with taxes and fees
9.2/10 Wonderful! (1,003 reviews)
Breakfast was amazing. Rooms are super clean. Staff is friendly.

Reviewed on Mar 27, 2026

Hyatt Place Manati
Hotel El Guajataca

Hotel El Guajataca

3.5 out of 5
Carretera 2 Km. 103.8 Quebradillas
$124 nightly
The price is $136 total per night from Apr 7 to Apr 8
$136 total
Apr 7 - Apr 8
Total with taxes and fees
8.4/10 Very Good! (1,001 reviews)
I loved this place! The room was a little far and downhill but to me it didn’t matter because as soon as I opened the door to my room I was greeted to a balcony room overlooking a beautiful ocean view! I slept the whole night with the door to the balcony open just to hear the waves crashing! The ...

Reviewed on Mar 24, 2026

Hotel El Guajataca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santana Vacation Packages

Santana Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Top Sights
La Poza Beach, Arecibo Observatory and Cueva Ventana

More vacations you might like

Frequently asked questions

How much does a Santana vacation package cost?
You can snap up a vacation package to this popular destination from $633 on Expedia. However, how much your vacation to Santana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santana?
You can typically find reduced prices and greater availability in August, September and December. Check out our cheap Santana vacation packages and you could score some great off-season discounts.
How many days is enough for Santana?
With a well-organized travel plan, you can easily tick off the main Santana sights in a few days. But if you prefer to discover hidden spots or go on day trips, think about booking your Santana vacation for longer.
How to find the best Santana package deals?
Finding a cheap Santana package deal is a breeze with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your budget, add a few filters and see what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most affordable Santana package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are usually lower.
Is it cheaper to book a Santana vacation as a package?
An Expedia vacation package could score you significant savings when compared to arranging flights and accommodations separately. Better still, you can customize your Santana escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santana?
Land incredible bargains by booking your flights early with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for an impromptu Santana trip.
Does Expedia offer Book Now, Pay Later Santana vacation packages?
Your Santana break is meant to be an escape from your daily routine, not a source of money-related stress. So to give you more flexibility, we've teamed up with online lender Affirm to offer our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and spread the total cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.