Santana Vacations from $658

Book a Hotel + Flight or Car together to unlock savings

Your Santana Vacation

Book a Santana vacation package and get set for a fantastic adventure. Well known for its beaches and cultural experiences, there's tons to love about this captivating city. A trip to Santana is a terrific opportunity to do a bit of sightseeing. Be sure to visit renowned attractions like Cueva Ventana, Arecibo Lighthouse and La Poza Beach. Whatever your travel plans or budget, organizing your ultimate tailored Santana vacation is simple with Expedia.

The Latest Santana Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • A modern building with a unique curved roof structure and a central water feature.
    Jan 10 - Jan 14

    Hotel Puerto Valdes + Flight

    Puerta de Tierra
    4 nights
    4.0 star property
    8.8/10 - Excellent (765 reviews)
    "Staff was excellent and very helpful during our stay especially Hector. Unfortunately the shuttle has been out of service and the hot tub needed cleaning. There were several other issues we encountered that were rectified by the Hector as well as other staff members at the time of need."
    Reviewed November 7, 2026
    Roundtrip • Boston (BOS) - San Juan (SJU)
    BOS - SJU • Nonstop SJU - BOS • 1 stop
    $1,040
    $658
    per traveler
    found 2 days ago
    Hotel Puerto Valdes
  • A modern two-story house with a swimming pool, surrounded by lush greenery.
    Jan 18 - Jan 23

    WALD HAUS by DW + Flight

    Naguabo
    5 nights
    4.0 star property
    9.2/10 - Wonderful (11 reviews)
    "The home itself is absolutely stunning but the road to the villa is not just narrow, it's washed out in many places, we struggled to navigate the potholes even with a jeep and an SUV, I would not drive it at night. There are great amenities like the fridge and bathroom downstairs, the coffee / cocktail bar is fabulous.The kitchen was well-stocked with basic spices and supplies but it was crawling with roaches. Wifi is spotty so be sure to have the guidebook downloaded and screenshots of the..."
    Reviewed August 13, 2026
    Roundtrip • Boston (BOS) - San Juan (SJU)
    BOS - SJU • Nonstop SJU - BOS • 1 stop
    $3,866
    $2,456
    per traveler
    found 1 day ago
    WALD HAUS by DW
  • A private infinity pool with a wooden deck and metal railings, surrounded by lush greenery and a scenic view of distant hills.
    Jan 18 - Jan 23

    SELVA by DW + Flight

    Pitahaya
    5 nights
    4.0 star property
    10/10 - Exceptional (3 reviews)
    "Todo estuvo perfecto limpieza 💯communication al 💯 y los servicios ofrecido todo me parecio exelente buen olor en las toallas y sabanas ,"
    Reviewed June 25, 2026
    Roundtrip • Boston (BOS) - San Juan (SJU)
    BOS - SJU • Nonstop SJU - BOS • 1 stop
    $5,220
    $3,376
    per traveler
    found 1 day ago
    SELVA by DW
  • A pool area with a hammock, lounge chairs, and a view of a white building with a balcony.
    Jan 14 - Jan 20

    Villa Gaviota with private pool by Otium + Flight

    Zarzal
    6 nights
    3.0 star property
    Roundtrip • Boston (BOS) - San Juan (SJU)
    BOS - SJU • Nonstop SJU - BOS • 2 stops
    $3,061
    $2,004
    per traveler
    found 1 day ago
    Villa Gaviota with private pool by Otium
  • A bedroom with a bed, a view of the ocean, a ceiling fan, and a painting on the wall.
    Jan 10 - Jan 16

    Ocean Breeze Villa + Flight

    Puerta de Tierra
    6 nights
    4.0 star property
    9.2/10 - Wonderful (45 reviews)
    "Room was very clean and accessible to major parts I wanted to see in the city. No food or drink available and no conditioner in the shower. I didn't access the pool but the staff was kind."
    Reviewed November 10, 2026
    Roundtrip • Boston (BOS) - San Juan (SJU)
    BOS - SJU • Nonstop SJU - BOS • 2 stops
    $1,846
    $1,210
    per traveler
    found 1 day ago
    Ocean Breeze Villa

Santana Hotel Deals

A hotel room with a bed, a nightstand, a lamp, and a bathroom visible through an open door.

Arecibo Inn

Arecibo Inn
3.0 star property
0.8 mi from Santana
8.0 out of 10, Very good, (1,044 reviews)
"👍🏻"
$102 nightly
The price is $111
Nov 12 - Nov 13
Total with taxes and fees
Arecibo Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in Santana

Frequently Asked Questions

How much does a Santana vacation package cost?

You can snap up a vacation package to this popular destination from $658 on Expedia. However, how much your vacation to Santana costs will depend on the season, hotel choice and length of stay.

What are the cheapest months to go to Santana?

You can typically find reduced prices and greater availability in August, September and December. Check out our cheap Santana vacation packages and you could score some great off-season discounts.

How many days is enough for Santana?

With a well-organized travel plan, you can easily tick off the main Santana sights in a few days. But if you prefer to discover hidden spots or go on day trips, think about booking your Santana vacation for longer.

How to find the best Santana package deals?

Finding a cheap Santana package deal is a breeze with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your budget, add a few filters and see what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most affordable Santana package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are usually lower.

Is it cheaper to book a Santana vacation as a package?

An Expedia vacation package could score you significant savings when compared to arranging flights and accommodations separately. Better still, you can customize your Santana escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.

When to book a vacation package to Santana?

Land incredible bargains by booking your flights early with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for an impromptu Santana trip.

Does Expedia offer Book Now, Pay Later Santana vacation packages?

Your Santana break is meant to be an escape from your daily routine, not a source of money-related stress. So to give you more flexibility, we've teamed up with online lender Affirm to offer our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and spread the total cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.