Santana Vacations from $354

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Your Santana Vacation

Book a Santana vacation package and get set for a fantastic adventure. Well known for its beaches and cultural experiences, there's tons to love about this captivating city. A trip to Santana is a terrific opportunity to do a bit of sightseeing. Be sure to visit renowned attractions like Cueva Ventana, Arecibo Lighthouse and La Poza Beach. Whatever your travel plans or budget, organizing your ultimate tailored Santana vacation is simple with Expedia.

The Latest Santana vacation packages

Price found within the past 48 hours. Click for updated prices.
Coral by the Sea Hotel
Placid Suites
Isla Verde Beachfront Retreat With Parking
ESJ Beach Hotel
Serena Boutique Hotel
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Discover the most popular places to visit in Santana

What to do in Santana

Santana Hotel Deals

Arecibo Inn

Arecibo Inn

3 out of 5
Road #2 km 67.2 Arecibo
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $96 total per night from Nov 18 to Nov 19
$96 total
Nov 18 - Nov 19
Total with taxes and fees
7.8/10 Good! (1,006 reviews)
Limpio, tranquilo y buen servicio.

Reviewed on Nov 9, 2025

Arecibo Inn
Hyatt Place Manati

Hyatt Place Manati

3.5 out of 5
122 Carretera PR-2 Manati
Fully refundableReserve now, pay when you stay
$212 nightly
The price is $235 total per night from Nov 23 to Nov 24
$235 total
Nov 23 - Nov 24
Total with taxes and fees
9.2/10 Wonderful! (1,001 reviews)
I had a pleasant stay

Reviewed on Nov 13, 2025

Hyatt Place Manati
Hotel El Guajataca

Hotel El Guajataca

3.5 out of 5
Carretera 2 Km. 103.8 Quebradillas
$99 nightly
The price is $108 total per night from Nov 25 to Nov 26
$108 total
Nov 25 - Nov 26
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
Staff was excellent

Reviewed on Nov 10, 2025

Hotel El Guajataca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santana Vacation Packages

Santana Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Top Sights
La Poza Beach, Arecibo Observatory and Cueva Ventana

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Frequently asked questions

How much does a Santana vacation package cost?
You can snap up a vacation package to this popular destination from $354 on Expedia. However, how much your vacation to Santana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santana?
You can typically find reduced prices and greater availability in August, September and December. Check out our cheap Santana vacation packages and you could score some great off-season discounts.
How many days is enough for Santana?
With a well-organized travel plan, you can easily tick off the main Santana sights in a few days. But if you prefer to discover hidden spots or go on day trips, think about booking your Santana vacation for longer.
How to find the best Santana package deals?
Finding a cheap Santana package deal is a breeze with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your budget, add a few filters and see what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most affordable Santana package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are usually lower.
Is it cheaper to book a Santana vacation as a package?
An Expedia vacation package could score you significant savings when compared to arranging flights and accommodations separately. Better still, you can customize your Santana escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santana?
Land incredible bargains by booking your flights early with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for an impromptu Santana trip.
Does Expedia offer Book Now, Pay Later Santana vacation packages?
Your Santana break is meant to be an escape from your daily routine, not a source of money-related stress. So to give you more flexibility, we've teamed up with online lender Affirm to offer our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and spread the total cost over 3, 6 or 12 months. Plus, there are no hidden costs or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.