A coastal town with a beach, marina, and white buildings surrounded by greenery and mountains.

Santiago Vacations from $650

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Santiago Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Sep 2 - Sep 7

    Hotel Marina Puerto Dorado + Flight

    Manzanillo
    5 nights
    3.0 star property
    6.2/10 - (100 reviews)
    "La comida es buena, la playa es muy bonita. Personal muy amable. Las habitaciones les falta una manita de gato. Pero relación costo beneficio quedamos satisfechos."
    Reviewed November 30, 2025
    Roundtrip Tijuana (TIJ) - Manzanillo (ZLO)
    TIJ - ZLO1 stop ZLO - TIJ1 stop
    Save 100% on your flight
    $1,007
    $650
    per traveler
    found 18 hours ago
    Hotel Marina Puerto Dorado
  • Oct 8 - Oct 13

    Grand Isla Navidad Golf & Spa Resort with Marina + Flight

    Isla Navidad
    5 nights
    4.5 star property
    8.8/10 - Excellent (1,000 reviews)
    "The property was very well maintained. The rooms were very clean. We had a very good time. Very rested and comfortable. Just what we needed."
    Reviewed July 21, 2026
    Roundtrip Los Angeles (LAX) - Manzanillo (ZLO)
    LAX - ZLONonstop ZLO - LAX1 stop
    Save 100% on your flight
    $1,560
    $842
    per traveler
    found 15 hours ago
    Grand Isla Navidad Golf & Spa Resort with Marina
  • Oct 6 - Oct 11

    Tesoro Manzanillo All Inclusive + Flight

    Peninsulas de Santiago
    5 nights
    3.0 star property
    7.6/10 - Good (1,001 reviews)
    "The beach view was amazing and clean rooms as well."
    Reviewed July 24, 2026
    Roundtrip Tijuana (TIJ) - Manzanillo (ZLO)
    TIJ - ZLO1 stop ZLO - TIJ1 stop
    Save 100% on your flight
    $1,743
    $1,080
    per traveler
    found 1 day ago
    Tesoro Manzanillo All Inclusive
  • Sep 15 - Sep 20

    El Corazón Golf & Spa Resort Manzanillo + Flight

    Manzanillo
    5 nights
    4.0 star property
    10/10 - Exceptional (15 reviews)
    "Corazon resort was hands down the best place we’ve ever had the pleasure of staying at. From the exceptional staff who froze the marlin we caught on our deep sea fishing excursion and prepared not 1 but 2 delicious gourmet meals for our group to the accommodating staff all around pool/shuttle/house keeping/chefs/management/wait staff. They get to know you by name. It is with our utmost enthusiasm that we recommend this beautiful property and superb staff. You won’t be dissatisfied."
    Reviewed November 12, 2025
    Roundtrip Los Angeles (LAX) - Manzanillo (ZLO)
    LAX - ZLO1 stop ZLO - LAX1 stop
    Save 100% on your flight
    $1,489
    $973
    per traveler
    found 12 hours ago
    El Corazón Golf & Spa Resort Manzanillo
  • Oct 8 - Oct 13

    Las Hadas By Brisas + Flight

    Las Hadas
    5 nights
    4.0 star property
    8.6/10 - Excellent (1,001 reviews)
    Roundtrip Los Angeles (LAX) - Manzanillo (ZLO)
    LAX - ZLONonstop ZLO - LAX1 stop
    $1,215
    $822
    per traveler
    found 15 hours ago
    Las Hadas By Brisas

What to do near Santiago

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.