Santiago Vacations from $805

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Your Santiago Vacation

Santiago is beckoning! Whatever type of escape you're planning, you can see and experience the best of this neighborhood with a Santiago vacation package. Kick off your trip to Santiago by visiting nearby attractions such as Playa Miramar, Playa La Audiencia and Playa Olas Altas. No matter your travel plans or budget, booking your perfect Santiago vacation is a cinch with Expedia.

The Latest Santiago Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Costa Brava
Barceló Karmina All Inclusive
Grand Isla Navidad Golf & Spa Resort with Marina
Las Hadas By Brisas
Tesoro Manzanillo All Inclusive

Where to stay in Santiago

Find the best Santiago areas and neighborhoods for the activities you enjoy most. Learn more about Santiago

Santiago Hotel Deals

Hotel Posada Santiago Manzanillo

Hotel Posada Santiago Manzanillo

2.5 out of 5
Miguel de La Madrid Hurtado 28 Manzanillo COL
4.6/10 (26 reviews)
Very basic hotel
"This hotel is very basic and its price is low. You get what you pay for. It is not very clean, unless you get a room with air conditioning because it is considered a premium room. Otherwise the room is not clean. We booked a room with air conditioning but at first they gave us a room without AC. ..."

Reviewed on Dec 29, 2020

Hotel Posada Santiago Manzanillo
Las Hadas By Brisas

Las Hadas By Brisas

4 out of 5
Ave Vista Hermosa S N Manzanillo COL
Fully refundable
$146 nightly
The price is $173 total per night from Jun 28 to Jun 29
$173 total
Jun 28 - Jun 29
Total with taxes and fees
8.6/10 Excellent! (1,011 reviews)
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Reviewed on Jun 8, 2026

Las Hadas By Brisas
Barceló Karmina All Inclusive

Barceló Karmina All Inclusive

4 out of 5
Avenida Vista Hermosa, 13 Manzanillo COL
$218 nightly
The price is $259 total per night from Jun 28 to Jun 29
$259 total
Jun 28 - Jun 29
Total with taxes and fees
8.6/10 Excellent! (1,217 reviews)
"When we booked hotel it said that it was family friendly and it most definite was not. It had multiple pools that were adult only, there was only one very very small pool for children most arras where not accesible or kid friendly. A la carte restaurants did not allowed children. We stayed 4d/3n ..."

Reviewed on Jun 10, 2026

Barceló Karmina All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.