Santo Domingo Vacations from $358

Book a Hotel + Flight or Car together to unlock savings

Your Santo Domingo Vacation

Your next big journey is just around the corner with a vacation package to Santo Domingo. Entertainment, food and nonstop good times — you're bound to find it in this neighborhood. Orange Blossom Hills Golf & Country Club and Lakes Of Lady Lake Golf Club are just a couple of the nearby attractions to add to your itinerary during a trip to Santo Domingo. Expedia can help turn your ideal Santo Domingo vacation into reality, no matter your travel plans or budget.

The Latest Santo Domingo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Westgate Blue Tree Resort in Lake Buena Vista
Margaritaville Cottages Orlando by Vstays with H2O Waterpark
Seasons Florida Resort
Disney's Animal Kingdom Lodge
Westgate Cocoa Beach Resort

Where to stay in Santo Domingo

Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most. Learn more about Santo Domingo

Santo Domingo Hotel Deals

Equus Inn Ocala

Equus Inn Ocala

2.5 out of 5
3434 Sw College Rd Ocala FL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Dec 7 to Dec 8
$94 total
Dec 7 - Dec 8
Total with taxes and fees
Equus Inn Ocala
The Waterfront Inn

The Waterfront Inn

3 out of 5
1105 Lake Shore Drive The Villages FL
$130 nightly
The price is $139 total per night from Nov 29 to Nov 30
$139 total
Nov 29 - Nov 30
Total with taxes and fees
9.4/10 Exceptional! (1,571 reviews)
"Great stay! We actually coming back in November! Very excited!"

Reviewed on Nov 6, 2026

The Waterfront Inn
Brownwood Hotel & Spa

Brownwood Hotel & Spa

3 out of 5
3003 Brownwood Blvd Wildwood FL
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $152 total per night from Nov 29 to Nov 30
$152 total
Nov 29 - Nov 30
Total with taxes and fees
9.8/10 Exceptional! (1,492 reviews)
"Brownwood is the absolute best! We have stayed there many times and had an excellent experience each time."

Reviewed on Nov 6, 2026

Brownwood Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.