Santo Tomás Vacations from $750

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Santo Tomás Vacation

Reserving a Santo Tomás vacation package is a great way to become familiar with this unique neighborhood. From its hot spots to its lesser-known gems, there's a lot to delve into. Hoping to do some sightseeing during your trip to Santo Tomás? Be sure to check out nearby attractions such as New Cathedral of Salamanca, San Esteban Convent and Art Nouveau and Art Deco Museum. Expedia can help you turn your dream Santo Tomás vacation into reality, no matter your budget or travel plans.

The Latest Santo Tomás Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Petit Hostel Palacio Real

Petit Hostel Palacio Real

2 out of 5
Moncloa-Aravaca
Price was $1,100, price is now $750 per person
$750
per person
Oct 25 - Oct 31
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
8.8/10 Excellent! (390 reviews)
Everything was great! Staff was helpful! We were comfortable. However, our bathroom was only cleaned once and the room was hot. Everything else was great

Reviewed on Aug 20, 2025

Hotel Atlantico Madrid

Hotel Atlantico Madrid

4 out of 5
Madrid Centro
Save 100% on your flight
Price was $1,482, price is now $899 per person
$899
per person
Nov 6 - Nov 11
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9.8/10 Exceptional! (2,133 reviews)
Large, comfortable, quiet room. Very helpful staff. Street area outside is noisy and crowded but you do not hear in the room. Hotel is located within walking distance to attractions and also convenient to Metro.

Reviewed on Sep 3, 2025

Hotel Riu Plaza España

Hotel Riu Plaza España

4 out of 5
Madrid Centro
Save 100% on your flight
Price was $1,571, price is now $957 per person
$957
per person
Nov 6 - Nov 11
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Madrid (MAD)
9.4/10 Exceptional! (4,310 reviews)
Very attentive staff fluent in English, which was very helpful for me. My room was great. Had a little porch attached to it. The rooftop was fantastic a magnificent view of the city. Again, compliments to the staff, especially at the front desk the doorman the person who help with my luggage. Everyone was great. I enjoyed the breakfast buffet, but one complaint would be that the crowds of people seemed a little chaotic. Everyone was going in their own direction and there should have been an orderly flow.

Reviewed on Sep 3, 2025

Casa Faraona Luxury Residences

Casa Faraona Luxury Residences

4 out of 5
Salamanca
Save 100% on your flight
Price was $4,977, price is now $3,257 per person
$3,257
per person
Nov 13 - Nov 18
found 1 day ago
Roundtrip flight included
New York (JFK) to Madrid (MAD)
9.6/10 Exceptional! (33 reviews)
Perfect location. Excelent room, it even had a sauna!

Reviewed on Jun 9, 2025

The First One Madrid Preciados

The First One Madrid Preciados

4 out of 5
Madrid Centro
Save 100% on your flight
Price was $1,446, price is now $960 per person
$960
per person
Nov 13 - Nov 18
found 1 day ago
Roundtrip flight included
New York (JFK) to Madrid (MAD)
9/10 Wonderful! (739 reviews)
Julian was the best!!!! the room the location everything was a dream.

Reviewed on Sep 1, 2025

Where to stay in Santo Tomás

Find the best Santo Tomás areas and neighborhoods for the activities you enjoy most. Learn more about Santo Tomás
Plaza Mayor showing a square or plaza, outdoor eating and heritage elements

Salamanca Centro

9 out of top 10 points of interest in this area

Salamanca Centro is noteworthy for its historic sites, and you can make a stop at top attractions like Plaza Mayor and Casa de las Conchas.

Find hotels in Salamanca Centro

Santo Tomás Hotel Deals

Exe Salamanca

Exe Salamanca

4 out of 5
Calle Alava, 8, Salamanca, Salamanca
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $87 total per night from Sep 8 to Sep 9
$87 total
Sep 8 - Sep 9
Total with taxes and fees
Exe Salamanca
ibis Salamanca

ibis Salamanca

2 out of 5
Calle la Marina 15-19, Salamanca, Salamanca
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $70 total per night from Sep 30 to Oct 1
$70 total
Sep 30 - Oct 1
Total with taxes and fees
ibis Salamanca
Hotel Sercotel Las Torres Salamanca

Hotel Sercotel Las Torres Salamanca

3 out of 5
C/ Concejo Nº 4, Salamanca
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $69 total per night from Sep 10 to Sep 11
$69 total
Sep 10 - Sep 11
Total with taxes and fees
Hotel Sercotel Las Torres Salamanca
See all 307 properties in Santo Tomás
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Santo Tomás

Plaza Mayor

Plaza Mayor

5/5(77 reviews)

Gaze up at the majestic walls enclosing the heart of one of Spain’s most lively plazas where cobblestone paths pass upscale boutiques and restaurants serving traditional tapas.

Plaza Mayor
University of Salamanca

University of Salamanca

5/5(58 reviews)

Marvel at the historic buildings and learn about the student culture in one of the oldest educational institutions in the world.

University of Salamanca
San Esteban Convent

San Esteban Convent

5/5(48 reviews)

Go on a self-guided tour of the church, chapels and cloister of this centuries-old convent. Admire gorgeous religious art and see where a saint confessed her sins.

San Esteban Convent

Things to do

Salamanca: Miguel de Cervantes walking tour

Salamanca: Miguel de Cervantes walking tour

$140
per traveler
Salamanca: Miguel de Cervantes walking tour
The Best of Salamanca Evening

The Best of Salamanca Evening (English)

$53
per adult
The Best of Salamanca Evening (English)
Salamanca: Private Sightseeing & Cultural Walking Tour

Salamanca: Private Sightseeing & Cultural Walking Tour

$199
per traveler
Salamanca: Private Sightseeing & Cultural Walking Tour
See all activities in Salamanca
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.