Title: Top 10 Hotels in Santo Tomé from $21 - Competitive Prices | Expedia.com [Vacation Rentals in Santo Tomé](https://expedia.com/Santo-Tome-Vacation-Rentals.d553248634664633910.Travel-Guide-VacationRentals)[Car Rentals in Santo Tomé](https://expedia.com/Car-Rentals-In-Santo-Tome.d553248634664633910.Car-Rental-Guide)[Santo Tomé Vacation Packages](https://expedia.com/Santo-Tome.d553248634664633910.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Apr 7 - Apr 8](https://www.expedia.com/Hotel-Search?regionId=553248634664633910&startDate=2026-04-07&endDate=2026-04-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 8 - Apr 9](https://www.expedia.com/Hotel-Search?regionId=553248634664633910&startDate=2026-04-08&endDate=2026-04-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248634664633910&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=553248634664633910&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanto-Tome-Hotels.d553248634664633910.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanto-Tome-Hotels.d553248634664633910.Travel-Guide-Hotels) ## Top Santo Tomé Hotel Reviews ## More cheap stays in Santo Tomé ![Hostel Sudaka](https://images.trvl-media.com/lodging/113000000/112380000/112379400/112379357/3e964d8c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hostel Sudaka Thay Morgenstern y La Quiaca Garupá Misiones $21 nightly $21 total Apr 21 - Apr 22 [](https://expedia.com/Garupa-Hotels-Hostel-Sudaka.h112379357.Hotel-Information) ![Turismo Hotel Casino](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/a0b30be4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Turismo Hotel Casino 650 Entre Ríos Corrientes Corrientes $102 nightly $102 total Apr 19 - Apr 20 8/10 Very Good! (4 reviews) [](https://expedia.com/Corrientes-Hotels-Turismo-Hotel-Casino.h120517502.Hotel-Information) ![Hotel Casino Rio Uruguay](https://images.trvl-media.com/lodging/123000000/122660000/122659600/122659562/bb78e4e4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Casino Rio Uruguay RN117 Paso de los Libres Corrientes [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F21%2F2026&endDate=4%2F22%2F2026&selected=122659562&PinnedHotelID=122659562&HadPinnedHotel=true®ionId=553248634664633910) 10/10 Exceptional! (1 review) [](https://expedia.com/Paso-De-Los-Libres-Hotels-Hotel-Casino-Rio-Uruguay.h122659562.Hotel-Information) ![Apart Hotel Las Violetas](https://images.trvl-media.com/lodging/92000000/91280000/91272000/91271956/0b3e9773_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Apart Hotel Las Violetas Barrio del Lago Candelaria Misiones [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F21%2F2026&endDate=4%2F22%2F2026&selected=91271956&PinnedHotelID=91271956&HadPinnedHotel=true®ionId=553248634664633910) [](https://expedia.com/Candelaria-Hotels-Apart-Hotel-Las-Violetas.h91271956.Hotel-Information) ![Niyat Urban Hotel](https://images.trvl-media.com/lodging/16000000/15370000/15363300/15363217/2541162b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Niyat Urban Hotel Hipolito Yrigoyen 83 Resistencia Chaco Province [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F21%2F2026&endDate=4%2F22%2F2026&selected=15363217&PinnedHotelID=15363217&HadPinnedHotel=true®ionId=553248634664633910) 8/10 Very Good! (14 reviews) [](https://expedia.com/Resistencia-Hotels-Niyat-Urban-Hotel.h15363217.Hotel-Information) ![Guarumba Apart Hotel](https://images.trvl-media.com/lodging/5000000/4120000/4115900/4115836/1920d0e6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Guarumba Apart Hotel Paraná 479 Federacion Entre Rios [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F21%2F2026&endDate=4%2F22%2F2026&selected=4115836&PinnedHotelID=4115836&HadPinnedHotel=true®ionId=553248634664633910) [](https://expedia.com/Federacion-Hotels-Guarumba-Apart-Hotel.h4115836.Hotel-Information) ## Frequently asked questions ### If I need to cancel my hotel reservation in Santo Tomé, will I receive a refund? ### Where can I learn more about changing or cancelling my trip to Santo Tomé? ### What should I see while I'm in Santo Tomé? ### What's the weather like in Santo Tomé? ## Explore a world of travel with Expedia - Lodging - Cars - More ways to book - [Estación Torrent Hotels ](https://www.expedia.com/Estacion-Torrent-Hotels.d553248635924012274.Travel-Guide-Hotels) - [Santo Tomé Department Hotels ](https://www.expedia.com/Destinations-In-Santo-Tome-Department.d553248635975751431.Hotel-Destinations) - [Car rentals near Estación Torrent ](https://www.expedia.com/Car-Rentals-In-Estacion-Torrent.d553248635924012274.Car-Rental-Guide) - [Book Hotels in Santo Tomé on Expedia.com.ar ](https://www.expedia.com.ar/Santo-Tome-Hoteles.d553248634664633910.Guia-de-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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