Santo Vacations from $685

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The Latest Santo vacation packages

Price found within the past 48 hours. Click for updated prices.
Eurostars Florence Boutique

Eurostars Florence Boutique

4 out of 5
Historic Centre of Florence
Price was $949, price is now $685 per person
$685
per person
Feb 26 - Mar 3
found 19 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
8.6/10 Excellent! (476 reviews)
The room was clean and the staff very accommodating. The breakfast was quite sufficient and had a good variety. The location is great. It's a short walk from the square, shopping and from restaurants.

Reviewed on Dec 13, 2025

Dimora Palanca Boutique & SPA

Dimora Palanca Boutique & SPA

5 out of 5
Historic Centre of Florence
Price was $1,374, price is now $1,069 per person
$1,069
per person
Mar 9 - Mar 13
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Florence (FLR)
9.4/10 Exceptional! (59 reviews)
I particularly love the authenticity of the building being hundreds of hundreds of years old and yet well cut, beautiful staff beautiful spa only lacking in the dining aspect but everything else was perfect. Highly recommend but recommend going out for dinner.

Reviewed on Nov 5, 2025

Hotel Duomo Firenze

Hotel Duomo Firenze

3 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was $1,463, price is now $967 per person
$967
per person
Feb 28 - Mar 6
found 1 day ago
Roundtrip flight included
Boston (BOS) to Florence (FLR)
9.2/10 Wonderful! (1,002 reviews)
The rooms were great, and the location is outstanding! Located right beside the Duomo. And the family-run establishment offered impeccable service. Highly recommend.

Reviewed on Dec 4, 2025

Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Price was $1,129, price is now $763 per person
$763
per person
Mar 2 - Mar 8
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,002 reviews)
Fantastic location, exceptionally good staff, situated close to all amenities, shopping , public transport, site seeing, highly recommended

Reviewed on Dec 11, 2025

The St. Regis Florence

The St. Regis Florence

5 out of 5
Historic Centre of Florence
Price was $2,593, price is now $1,849 per person
$1,849
per person
Feb 16 - Feb 21
found 1 day ago
Roundtrip flight included
Boston (BOS) to Florence (FLR)
9.6/10 Exceptional! (261 reviews)
Nice property in a great location.

Reviewed on Jun 29, 2025

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Santo Hotel Deals

Hotel Athena

Hotel Athena

4 out of 5
P Mascagni 55 Siena SI
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $100 total per night from Jan 8 to Jan 9
$100 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
9.2/10 Wonderful! (1,003 reviews)
Excellent hotel, very helpful staff, highly recommended

Reviewed on Dec 6, 2025

Hotel Athena
Palazzo Ravizza

Palazzo Ravizza

4 out of 5
Pian dei Mantellini 34 Siena SI
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $118 total per night from Dec 14 to Dec 15
$118 total
Dec 14 - Dec 15
Total with taxes and fees
9.2/10 Wonderful! (745 reviews)
Ideal in every way.

Reviewed on Dec 2, 2025

Palazzo Ravizza
Borgo Grondaie

Borgo Grondaie

3 out of 5
Strada delle Grondaie, 15 Siena SI
Fully refundable
$82 nightly
The price is $94 total per night from Jan 12 to Jan 13
$94 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
9.6/10 Exceptional! (439 reviews)
The sta

Reviewed on Nov 17, 2025

Borgo Grondaie
See all 2,909 properties in Santo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santo Vacation Packages

Santo Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Max Temp Winter
50ºF
Max Temp Summer
85ºF

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Frequently asked questions

How much does a Santo vacation package cost?
You'll find cheap prices from $685 on Expedia for your Santo break. However, a range of factors like the length of stay, the season and your choice of hotel will influence how much your vacation to Santo costs.
What are the cheapest months to go to Santo?
If you'd like to snag a cheap Santo vacation package, consider visiting in November, December and January. You'll typically find lower prices on hotels and airfares during these months — perfect for a budget-friendly break.
How many days is enough for Santo?
The ideal length of your Santo vacation depends on what you'd like to do. Usually, a handful of days to a week will give you time to visit all the top sights and discover some hidden treasures along the way.
How to find the best Santo package deals?
Start your search for a Santo package deal by entering your destination and preferred travel dates under our "Packages" tab. Then apply a few filters, like "Popular locations" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the ideal Santo package deal right away, just play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santo escape off to a flying start.
Is it cheaper to book a Santo vacation as a package?
An Expedia vacation package could land you great savings when compared to booking flights and stays individually. Better still, you can tailor your Santo trip to match your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santo?
If you have your Santo vacation dates locked in, book as soon as you can to snap up some outstanding deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for quick escapes.
Does Expedia offer Book Now, Pay Later Santo vacation packages?
Set off on your dream getaway to Santo with our Book Now, Pay Later vacations. No need to scrimp and save or wait until your next payday — we've teamed up with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the total cost across 3, 6 or 12 months. With no hidden or late payment fees, it's easy to budget for your trip and snap up travel deals before they disappear.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.