
Santo Vacations from $702
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to $1,045 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
The Latest Santo vacation packages
Price found within the past 48 hours. Click for updated prices.

Aurum Uffizi
Historic Centre of Florence
Save 100% on your flight
Price was $1,153, price is now $702 per person
$702
per person
Oct 31 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.8/10 Good! (1,000 reviews)
Our stay was lovely, very comfortable, small but good choice of breakfast.
Beds were comfy and room was clean when we arrived and cleaned everyday.
I would only suggest maybe for a shower curtains as when we had a shower the bathroom floor would be all wet, but easily to clean. And just a note on how to use the phone if we need to call reception but overall the hotel facilities and the staff were brilliant if i could give more then 5 stars i would.
Reviewed on Aug 19, 2025

Palazzo Firenze by Baglioni Hotels & Resorts
Historic Centre of Florence
Price was $19,005, price is now $9,312 per person
$9,312
per person
Oct 6 - Oct 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.4/10 Exceptional! (230 reviews)
I VERY MUCH ENJOYED THE STAY
Reviewed on Jul 18, 2025

The Moon Boutique Hotel & Spa
Historic Centre of Florence
Save 100% on your flight
Price was $1,343, price is now $723 per person
$723
per person
Oct 30 - Nov 4
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.6/10 Exceptional! (462 reviews)
The hotel is located a 25 min walk away from the heart of Florence so very easy to access the main attractions within the city. The hotel itself is immaculate and the staff are extremely helpful with dealing with any questions you may have. Being able to access the spa everyday for 1 and 30 minutes is an excellent perk as the facilities are well worth a visit, you are also able to book massages for an extra fee. The breakfast also gives a variety of options to start each day and the room itself is spacious, with the shower particularly being very comfortable.
Reviewed on Aug 13, 2025

Aurum Firenze
Historic Centre of Florence
Save 100% on your flight
Price was $1,644, price is now $1,008 per person
$1,008
per person
Sep 26 - Oct 1
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,007 reviews)
Great location. Few minutes away from train station. Not so quiet. You could hear people from outside even the windows closed. If you are staying for a few days, it’s a great location.
Reviewed on Aug 14, 2025

Villa di Piazzano - Small Luxury Hotel of the World
Save 100% on your flight
Price was $2,214, price is now $1,454 per person
$1,454
per person
Oct 21 - Oct 26
found 2 hours ago
Roundtrip non-stop flight included
New York (NYC) to Florence (FLR)
9.8/10 Exceptional! (218 reviews)
AMAZING! Gorgeous! I would recommend to everyone!
Reviewed on Jul 29, 2025
Santo Hotel Deals

Hotel Athena
P Mascagni 55, Siena, SI
Fully refundable
$167 nightly
The price is $189 total per night from Aug 20 to Aug 21
$189 total
Aug 20 - Aug 21
Total includes taxes and fees
9.2/10 Wonderful! (1,002 reviews)
"Older, more traditional style but excellent hotel. The staff are amazing, super kind and helpful. We were really impressed, and would definately stay here again."
Reviewed on Aug 14, 2025

Palazzo Ravizza
Pian dei Mantellini 34, Siena, SI
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $139 total per night from Aug 23 to Aug 24
$139 total
Aug 23 - Aug 24
Total includes taxes and fees
9.2/10 Wonderful! (686 reviews)
Just beautiful
"The building, the views, the staff, the food, everything was just incredible. It was so quiet we felt like we were the only people there until we went for breakfast and realised there were others in the hotel. The view from the our room at the back of the hotel over the Tuscan hills will live with ..."
Reviewed on Aug 9, 2025

NH Siena
Piazza La Lizza 1, Siena, SI
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $155 total per night from Aug 20 to Aug 21
$155 total
Aug 20 - Aug 21
Total includes taxes and fees
8.2/10 Very Good! (992 reviews)
"Everything good !"
Reviewed on Aug 11, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More vacations you might like
Frequently asked questions
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Bagni di Petriolo Hotels
- Farmstay in Bagni di Petriolo
- Hotels near Terme Petriolo
- Hotels near Basso Merse Nature Reserve
- Pari Hotels
- Villas in Pari
- Resorts in Lama
- Lama Hotels
- Town Houses in Casciano di Murlo
- Casciano di Murlo Hotels
- Villas in Casciano di Murlo
- 3 Star Hotels in Casciano di Murlo
- Civitella Paganico Hotels
- Villas in Civitella Paganico
- Winery Hotels in Civitella Paganico
- Villas in Castiglione del Bosco
- Castiglione del Bosco Hotels
- Murlo Hotels
- Resorts & Hotels with Spas in Murlo
- Lupompesi Hotels
- Hotels near I Canaloni del Torrente Farma
- 5 Star Hotels in Civitella Marittima
- Civitella Marittima Hotels
- Vacation Homes in Civitella Marittima
- Farmstay in Camigliano
- Winery Hotels in Brunello di Montalcino Wine Area
- 5 Star Hotels in Brunello di Montalcino Wine Area
- Farmstay in Brunello di Montalcino Wine Area
- Villas in Brunello di Montalcino Wine Area
- Brunello di Montalcino Wine Area Hotels
- Relais & Chateaux Hotels in Brunello di Montalcino Wine Area
- Luxury Hotels in Brunello di Montalcino Wine Area
- Hotels with Free Parking in Brunello di Montalcino Wine Area
- Romantic Hotels in Brunello di Montalcino Wine Area
- Hotels with Tennis Courts in Brunello di Montalcino Wine Area
- Hotels & Resorts for Couples in Brunello di Montalcino Wine Area
- Hotel Wedding Venues Hotels in Brunello di Montalcino Wine Area
- Golf Hotels in Brunello di Montalcino Wine Area
- Hotels with Restaurants in Brunello di Montalcino Wine Area
- Pet-friendly Hotels in Brunello di Montalcino Wine Area
- Ski Hotels in Brunello di Montalcino Wine Area
- Hotels with Laundry Facilities in Brunello di Montalcino Wine Area
- Monticiano Hotels
- Resorts & Hotels with Spas in Monticiano
- Hotel Wedding Venues Hotels in Monticiano
- Winery Hotels in Monticiano
- 5 Star Hotels in Monticiano
- Golf Hotels in Monticiano
- Beach Hotels in Monticiano
- Hotels near Val di Merse
- Monte Antico Hotels
- Hostels in Orgia
- Orgia Hotels
- Guest Houses in Orgia
- Visit Bagni di Petriolo
- Castello di Montepescini
- Basso Merse Nature Reserve
- Pari Vacations
- Visit Pari
- Visit Casale di Pari
- Lama Vacations
- Visit Tocchi
- Visit San Lorenzo a Merse
- Visit Casciano di Murlo
- Visit Civitella Paganico
- Castello del Belagaio
- Visit Castiglione del Bosco
- Abbey of San Lorenzo al Lanzo
- Visit Murlo
- Visit Vescovado
- Visit Lupompesi
- I Canaloni del Torrente Farma
- Brunello di Montalcino Wine Area Vacations
- Visit Camigliano
- Visit Brunello di Montalcino Wine Area
- Visit Monticiano
- Visit Monte Antico
- Visit Torniella
- Orgia Vacations
- Visit Scalvaia
- Capanna of Cencioni
- Visit Orgia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.