Santo Vacations from $1,620

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The Latest Santo vacation packages

Price found within the past 48 hours. Click for updated prices.
Residenza Florentia

Residenza Florentia

1 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was $2,609, price is now $1,620 per person
$1,620
per person
May 11 - May 17
found 4 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
8.6/10 Excellent! (47 reviews)
Location, accommodations, and communication. Simple but comfortable. A basic facilities, and nice AC, elevator, and luggage storage.

Reviewed on Jun 12, 2025

Hotel Alessandra

Hotel Alessandra

2 out of 5
Historic Centre of Florence
Price was $8,443, price is now $4,817 per person
$4,817
per person
Jun 9 - Jun 15
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Florence (FLR)
9.2/10 Wonderful! (853 reviews)
Staying here was a wonderful experience! Hotel Alessandra was within walking distance of everything we wanted to see in Florence, including one street away from the Ponte Vecchio. The room was always very clean and the staff was extremely welcoming and kind. We loved our stay here and would absolutely stay here on our next trip to Florence!

Reviewed on Mar 30, 2026

Hotel Berchielli

Hotel Berchielli

4 out of 5
Historic Centre of Florence
Price was $9,492, price is now $5,448 per person
$5,448
per person
Jun 9 - Jun 15
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Florence (FLR)
9.4/10 Exceptional! (1,001 reviews)
Very good Breakfast with many food options. Great service !

Reviewed on Jan 21, 2026

Hotel De La Ville

Hotel De La Ville

4 out of 5
Historic Centre of Florence
Price was $8,858, price is now $5,411 per person
$5,411
per person
Jun 2 - Jun 8
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Florence (FLR)
9.2/10 Wonderful! (1,003 reviews)
This was my second stay and my go to in Florence. Lovely hotel and staff and great location. Breakfast is expensive but everything in the core is. Only wish there was a plug by the bed for phone charging. They brought me an extension cord. Will stay again! Grazie.

Reviewed on Apr 1, 2026

The FRAME Hotel

The FRAME Hotel

4 out of 5
Historic Centre of Florence
Price was $9,024, price is now $5,593 per person
$5,593
per person
Jun 2 - Jun 8
found 1 day ago
Roundtrip flight included
Orlando (MCO) to Florence (FLR)
9.6/10 Exceptional! (623 reviews)
Staff was so nice! Room was clean and well maintained. Location is great would definitely come back

Reviewed on Mar 18, 2026

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Santo Hotel Deals

Hotel Chiusarelli

Hotel Chiusarelli

3 out of 5
Viale Curtatone 15 Siena SI
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $134 total per night from Apr 8 to Apr 9
$134 total
Apr 8 - Apr 9
Total with taxes and fees
8.8/10 Excellent! (1,000 reviews)
The hotel was just outside of the town, so the location was good. It was a beautiful property. The breakfast was good. Just be prepared to walk stairs. No lifts. But overall, good.

Reviewed on Mar 22, 2026

Hotel Chiusarelli
Palazzo Ravizza

Palazzo Ravizza

4 out of 5
Pian dei Mantellini 34 Siena SI
$150 nightly
The price is $171 total per night from Apr 6 to Apr 7
$171 total
Apr 6 - Apr 7
Total with taxes and fees
9.4/10 Exceptional! (770 reviews)
El jardín súper cómodo y a gusto para ver atardeceres

Reviewed on Apr 1, 2026

Palazzo Ravizza
Villa Scacciapensieri Boutique Hotel

Villa Scacciapensieri Boutique Hotel

4 out of 5
Strada di Scacciapensieri 10 Siena SI
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $173 total per night from Apr 3 to Apr 4
$173 total
Apr 3 - Apr 4
Total with taxes and fees
9.2/10 Wonderful! (424 reviews)
This hotel is a total scam. They state that no outside food or drinks are allowed on the premises. One night, staff saw us bringing a pizza back to our room but said nothing at the time. The next morning, they suddenly demanded a €50 fine. We tried to reason with them, but they insisted on charging ...

Reviewed on Mar 31, 2026

Villa Scacciapensieri Boutique Hotel
See all 2,868 properties in Santo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santo Vacation Packages

Santo Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Max Temp Winter
50ºF
Max Temp Summer
85ºF

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Frequently asked questions

How much does a Santo vacation package cost?
You'll find cheap prices from $1,620 on Expedia for your Santo break. However, a range of factors like the length of stay, the season and your choice of hotel will influence how much your vacation to Santo costs.
What are the cheapest months to go to Santo?
If you'd like to snag a cheap Santo vacation package, consider visiting in November, December and January. You'll typically find lower prices on hotels and airfares during these months — perfect for a budget-friendly break.
How many days is enough for Santo?
The ideal length of your Santo vacation depends on what you'd like to do. Usually, a handful of days to a week will give you time to visit all the top sights and discover some hidden treasures along the way.
How to find the best Santo package deals?
Start your search for a Santo package deal by entering your destination and preferred travel dates under our "Packages" tab. Then apply a few filters, like "Popular locations" and "Amenities," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the ideal Santo package deal right away, just play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santo escape off to a flying start.
Is it cheaper to book a Santo vacation as a package?
An Expedia vacation package could land you great savings when compared to booking flights and stays individually. Better still, you can tailor your Santo trip to match your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santo?
If you have your Santo vacation dates locked in, book as soon as you can to snap up some outstanding deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are ideal for quick escapes.
Does Expedia offer Book Now, Pay Later Santo vacation packages?
Set off on your dream getaway to Santo with our Book Now, Pay Later vacations. No need to scrimp and save or wait until your next payday — we've teamed up with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the total cost across 3, 6 or 12 months. With no hidden or late payment fees, it's easy to budget for your trip and snap up travel deals before they disappear.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.