
Santo Vacations from $626
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Santo vacation packages
Price found within the past 48 hours. Click for updated prices.


Eurostars Florence Boutique
Historic Centre of Florence
Save 100% on your flight
Price was $1,352, price is now $861 per person
$861
per person
Mar 13 - Mar 20
found 17 hours ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
8.6/10 Excellent! (476 reviews)
The room was clean and the staff very accommodating. The breakfast was quite sufficient and had a good variety. The location is great. It's a short walk from the square, shopping and from restaurants.
Reviewed on Dec 13, 2025

The Moon Boutique Hotel & Spa
Historic Centre of Florence
Save 100% on your flight
Price was $1,683, price is now $1,105 per person
$1,105
per person
Mar 13 - Mar 20
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
9.6/10 Exceptional! (495 reviews)
Everything—the breakfast, the staff, and the cleanliness—was perfect. The room was quiet and supremely comfortable. Highly recommend!
Reviewed on Nov 17, 2025

Hotel Duomo Firenze
Historic Centre of Florence
Save 100% on your flight
Price was $1,836, price is now $1,257 per person
$1,257
per person
Mar 13 - Mar 20
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
9.2/10 Wonderful! (1,002 reviews)
The breakfast was great, I don't drink but they have a pig leg and wine for breakfast that stood out. Free gelato all day long. Location spectacular. Only downside is small rooms (you are in Florence normal) and water pressure and temp was a struggle
Reviewed on Dec 22, 2025

Floren Hotel
Historic Centre of Florence
Save 100% on your flight
Price was $2,197, price is now $1,695 per person
$1,695
per person
Mar 13 - Mar 20
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
9.4/10 Exceptional! (201 reviews)
Excelente hotel and service
Reviewed on Dec 16, 2025
Santo Hotel Deals

Hotel Athena
P Mascagni 55 Siena SI
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $98 total per night from Jan 25 to Jan 26
$98 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
9.2/10 Wonderful! (1,002 reviews)
Great location, very friendly staff
Reviewed on Dec 13, 2025

Borgo Grondaie
Strada delle Grondaie, 15 Siena SI
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $93 total per night from Jan 7 to Jan 8
$93 total
Jan 7 - Jan 8, 2026
Total with taxes and fees
9.6/10 Exceptional! (439 reviews)
The sta
Reviewed on Nov 17, 2025

Palazzo Ravizza
Pian dei Mantellini 34 Siena SI
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $119 total per night from Jan 6 to Jan 7
$119 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
9.2/10 Wonderful! (749 reviews)
Having booked with another local hotel - The Athena - who were completely obnoxious and unhelpful regarding the parking. I stumbled across this gem. The staff were so helpful and accomplished ~ first class customer service.
Reviewed on Dec 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santo Vacation Packages
Santo Essential Information
Language | Italian |
|---|---|
Currency | Euros |
Local Welcome | Ciao |
Local Goodbye | Ciao |
Max Temp Winter | 50ºF |
Max Temp Summer | 85ºF |
More vacations you might like
Frequently asked questions
Explore a world of travel with Expedia
- Bagni di Petriolo Hotels
- Farmstay in Bagni di Petriolo
- Hotels near Terme Petriolo
- Hotels near Basso Merse Nature Reserve
- Pari Hotels
- Villas in Pari
- Resorts in Lama
- Lama Hotels
- Town Houses in Casciano di Murlo
- Casciano di Murlo Hotels
- Villas in Casciano di Murlo
- 3 Star Hotels in Casciano di Murlo
- Civitella Paganico Hotels
- Villas in Civitella Paganico
- Winery Hotels in Civitella Paganico
- Villas in Castiglione del Bosco
- Castiglione del Bosco Hotels
- Murlo Hotels
- Resorts & Hotels with Spas in Murlo
- Lupompesi Hotels
- Hotels near I Canaloni del Torrente Farma
- 5 Star Hotels in Civitella Marittima
- Civitella Marittima Hotels
- Vacation Homes in Civitella Marittima
- Farmstay in Camigliano
- Winery Hotels in Brunello di Montalcino Wine Area
- 5 Star Hotels in Brunello di Montalcino Wine Area
- Farmstay in Brunello di Montalcino Wine Area
- Villas in Brunello di Montalcino Wine Area
- Brunello di Montalcino Wine Area Hotels
- Relais & Chateaux Hotels in Brunello di Montalcino Wine Area
- Luxury Hotels in Brunello di Montalcino Wine Area
- Hotels with Free Parking in Brunello di Montalcino Wine Area
- Romantic Hotels in Brunello di Montalcino Wine Area
- Hotels with Tennis Courts in Brunello di Montalcino Wine Area
- Hotels & Resorts for Couples in Brunello di Montalcino Wine Area
- Hotel Wedding Venues Hotels in Brunello di Montalcino Wine Area
- Golf Hotels in Brunello di Montalcino Wine Area
- Hotels with Restaurants in Brunello di Montalcino Wine Area
- Pet-friendly Hotels in Brunello di Montalcino Wine Area
- Ski Hotels in Brunello di Montalcino Wine Area
- Hotels with Laundry Facilities in Brunello di Montalcino Wine Area
- Monticiano Hotels
- Resorts & Hotels with Spas in Monticiano
- Hotel Wedding Venues Hotels in Monticiano
- Winery Hotels in Monticiano
- 5 Star Hotels in Monticiano
- Golf Hotels in Monticiano
- Beach Hotels in Monticiano
- Hotels near Val di Merse
- Monte Antico Hotels
- Hostels in Orgia
- Orgia Hotels
- Guest Houses in Orgia
- Visit Bagni di Petriolo
- Castello di Montepescini
- Basso Merse Nature Reserve
- Pari Vacations
- Visit Pari
- Visit Casale di Pari
- Lama Vacations
- Visit Tocchi
- Visit San Lorenzo a Merse
- Visit Casciano di Murlo
- Visit Civitella Paganico
- Castello del Belagaio
- Visit Castiglione del Bosco
- Abbey of San Lorenzo al Lanzo
- Visit Murlo
- Visit Vescovado
- Visit Lupompesi
- I Canaloni del Torrente Farma
- Brunello di Montalcino Wine Area Vacations
- Visit Camigliano
- Visit Brunello di Montalcino Wine Area
- Visit Monticiano
- Visit Monte Antico
- Visit Torniella
- Orgia Vacations
- Visit Scalvaia
- Capanna of Cencioni
- Visit Orgia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.



















