Sefro Vacations from $1,337

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Sefro Vacation

Let our vacation packages to Sefro inspire your next escape. You'll find a whole lot to love about this interesting city, starting with the neighborhood of Costa, which is good for views and nature. If your trip to Sefro includes some sightseeing, don't miss major attractions such as Borgia Castle, MuPA Museo Paleontologico Archeologico and Ducal Palace of Camerino. Your dream Sefro vacation is a few clicks away. Browse flights, hotels and more on Expedia for a getaway that's tailored to suit your travel style.

The Latest Sefro vacation packages

Price found within the past 48 hours. Click for updated prices.
TH Assisi - Hotel Cenacolo

TH Assisi - Hotel Cenacolo

4 out of 5
Price was $1,396, price is now $1,337 per person
$1,337
per person
Jul 18 - Jul 22
found 12 hours ago
Roundtrip flight included
Chicago (ORD) to Ancona (AOI)
9.2/10 Wonderful! (661 reviews)
Great location when you go to Assisi by car

Reviewed on Apr 20, 2026

Sina Brufani

Sina Brufani

5 out of 5
Old Town Perugia
Price was $2,053, price is now $2,018 per person
$2,018
per person
Jun 26 - Jul 1
found 1 day ago
Roundtrip flight included
New York (NYC) to Ancona (AOI)
9.2/10 Wonderful! (632 reviews)
Breakfast was lovely. I did not use the spa. We had dinner on the property and it was the best meal and experience from our trip to Italy.

Reviewed on May 9, 2026

Don't see what you're looking for?
See all available trips from Columbus to Sefro
View all trips

Sefro Hotel Deals

TH Assisi - Hotel Cenacolo

TH Assisi - Hotel Cenacolo

4 out of 5
Viale Patrono d'Italia 70 Assisi PG
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $107 total per night from May 28 to May 29
$107 total
May 28 - May 29
Total with taxes and fees
9.2/10 Wonderful! (662 reviews)
Great location when you go to Assisi by car

Reviewed on Apr 20, 2026

TH Assisi - Hotel Cenacolo
BV Grand Hotel Assisi

BV Grand Hotel Assisi

4 out of 5
Via Giovanni Renzi No 2 Assisi PG
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $114 total per night from Jun 7 to Jun 8
$114 total
Jun 7 - Jun 8
Total with taxes and fees
8.6/10 Excellent! (335 reviews)
Excellent trip

Reviewed on Mar 20, 2026

BV Grand Hotel Assisi
Il Palazzo

Il Palazzo

3 out of 5
Via San Francesco 8 Assisi PG
$139 nightly
The price is $160 total per night from Jun 9 to Jun 10
$160 total
Jun 9 - Jun 10
Total with taxes and fees
9.6/10 Exceptional! (486 reviews)
The hotel facility was modern and clean. The location was also good. The staff and breakfast were excellent. Most hotels are on the the hill and highly recommend taking taxi to get to the hotel.

Reviewed on May 8, 2026

Il Palazzo
See all 1,244 properties in Sefro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Sefro Vacation Packages

Sefro Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Sant Egidio Airport (PEG)
Population
260
Max Temp Winter
45ºF
Max Temp Summer
80ºF
Top Sights
Parco Dinosauri Le Pietre del Drago, Borgia Castle and Lanciano Castle

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Sefro vacation package cost?
You'll find cheap prices from $1,337 on Expedia for your Sefro break. However, factors like your choice of hotel, the season and length of stay will influence how much your vacation to Sefro costs.
What are the cheapest months to go to Sefro?
You can generally find lower prices and better availability in November, December and January. Explore our cheap Sefro vacation packages and you could score some great off-season discounts.
How many days is enough for Sefro?
With a well-planned itinerary, you can easily tick off the most popular Sefro attractions in a handful of days. But if you'd like to discover hidden spots or go on day tours, think about booking your Sefro vacation for longer.
How to find the best Sefro package deals?
Begin your search for a Sefro package deal by entering your preferred travel dates and destination under our "Packages" tab. Then add a few filters, like "Property type" and "Guest rating," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the ideal Sefro package deal straight away, just play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Sefro adventure underway.
Is it cheaper to book a Sefro vacation as a package?
An Expedia vacation package could land you considerable savings when compared to arranging flights and stays individually. Better still, you can tailor your Sefro escape to match your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Sefro?
If you're considering a spur-of-the-moment Sefro trip, check out our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can score awesome deals on your flights and hotels by booking well in advance.
Does Expedia offer Book Now, Pay Later Sefro vacation packages?
Secure your perfect escape to Sefro with help from Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or wait for payday — we've joined forces with online lender Affirm to give you more flexibility with your finances. Our vacation packages with payment plans let you split the cost across 3, 6 or 12 months. With no hidden or late payment fees, it's a breeze to stick to your budget and snap up bargains before they sell out.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.