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St. Ann Vacation Rentals

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Check prices for these dates

In two weeks
Sep 11 - Sep 13
In two months
Oct 23 - Oct 25
In three months
Nov 20 - Nov 22
In four months
Dec 18 - Dec 20

Our top choices for St. Ann vacation rentals

A dining table set with plates, glasses, and a vase.

1. Cozy Cottage in the City

Cozy Cottage in the City
Saint Ann
9.2 out of 10, Wonderful, (5 reviews)
"This was a great house with comfortable beds and a very well equipped kitchen! The host was very accommodating and quick to respond. "
United States
Jennifer L.
$290 nightly
The price is $317
Aug 30 - Aug 31
Total with taxes and fees
Cozy Cottage in the City
A kitchen with a stainless steel sink, a countertop, and wooden flooring.

2. Delightful studio apartment with AC in Saint Ann

Delightful studio apartment with AC in Saint Ann
Saint Ann
Delightful studio apartment with AC in Saint Ann

3. Charming 1 bedroom with AC and WiFi in lovely Saint Ann

Charming 1 bedroom with AC and WiFi in lovely Saint Ann
Saint Ann
$158 nightly
The price is $174
Aug 31 - Sep 1
Total with taxes and fees
Charming 1 bedroom with AC and WiFi in lovely Saint Ann
A modern kitchen with a stone accent wall, a central island, and pendant lighting.

4. Lots of Space! Central to St Charles and STL. Newly Remodeled. Large Backyard!

Lots of Space! Central to St Charles and STL. Newly Remodeled. Large Backyard!
Pinehurst
8.6 out of 10, Excellent, (36 reviews)
"Our family, daughters/husbands and grandmother stayed at the rental for a three day weekend. The rental was very clean, the kitchen has new appliances and is well equipped. The beds were very comfortable and everyone got good nice sleeps. "
United States
Steve H.
$623 nightly
The price is $713
Sep 7 - Sep 8
Total with taxes and fees
Lots of Space! Central to St Charles and STL. Newly Remodeled. Large Backyard!

5. Great for Business Travelers! Comfortable Suite in St. Louis | BBQ Area

Great for Business Travelers! Comfortable Suite in St. Louis | BBQ Area
Westport
10.0 out of 10, Exceptional, (5 reviews)
"Everything from the staff to the amenities to the rooms were amazing! Definitely recommend staying here! "
Canada
Lashon C.
$249 nightly
The price is $283
Sep 13 - Sep 14
Total with taxes and fees
Great for Business Travelers! Comfortable Suite in St. Louis | BBQ Area
A hotel lobby with a staircase, a reception desk, and a chandelier.

6. 2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
Westport
9.8 out of 10, Exceptional, (38 reviews)
"Fantastic place!"
United States
Anonymous traveler
$65 nightly
The price is $75
Aug 31 - Sep 1
Total with taxes and fees
2 Queen Beds | Non-Smoking, Kitchen
A compact kitchen with white cabinets, a stainless steel refrigerator, a coffee maker, and a hanging pendant light.

7. Convenience 2 Bedroom House to Explore All of St Louis

Convenience 2 Bedroom House to Explore All of St Louis
University City
9.8 out of 10, Exceptional, (50 reviews)
"The house was immaculately clean and beds were extremely comfortable!"
United States
Anna M.
$246 nightly
The price is $266
Sep 27 - Sep 28
Total with taxes and fees
Convenience 2 Bedroom House to Explore All of St Louis
A neatly made bed with a stack of folded towels, a bedside lamp, and a ceiling fan in a room with a large window and a wall-mounted artwork.

8. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
9.8 out of 10, Exceptional, (10 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
$253 nightly
The price is $278
Sep 1 - Sep 2
Total with taxes and fees
Walk to Main | Pet-Friendly Yard & Workspace
A living room with a flat-screen TV, a sofa with patterned cushions, a coffee table, and a rug.

9. Cottage on Historic Main Street- Low Cleaning fee

Cottage on Historic Main Street- Low Cleaning fee
St. Charles Historic District
10.0 out of 10, Exceptional, (23 reviews)
"Great location to Main Street. "
United States
Daneen H.
$289 nightly
The price is $309
Aug 30 - Aug 31
Total with taxes and fees
Cottage on Historic Main Street- Low Cleaning fee
A modern kitchen with white cabinets, a built-in microwave, a stove, and a window providing natural light.

10. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (25 reviews)
"Great location"
United States
todd p.
$230 nightly
The price is $253
Sep 1 - Sep 2
Total with taxes and fees
Pet-Friendly Duplex | Historic Main
A modern kitchen with white cabinets, a black refrigerator, and a central island.

11. Cottage on Main st- Low Cleaning Fee

Cottage on Main st- Low Cleaning Fee
St. Charles Historic District
10.0 out of 10, Exceptional, (10 reviews)
"Good location. Decorated very nicely. "
United States
Debbie A.
$285 nightly
The price is $305
Sep 1 - Sep 2
Total with taxes and fees
Cottage on Main st- Low Cleaning Fee
A living room with a beige sofa, a wooden coffee table, and a ceiling fan.

12. Music House · Music House on Main Street at The Wine Garden

Music House · Music House on Main Street at The Wine Garden
Saint Charles
9.4 out of 10, Exceptional, (17 reviews)
$800 nightly
The price is $898
Aug 31 - Sep 1
Total with taxes and fees
Music House · Music House on Main Street at The Wine Garden
A modern kitchen with white cabinetry, stainless steel appliances, and a dining area with a wooden table and chairs.

13. Historic 1805 Main Street 2BR

Historic 1805 Main Street 2BR
St. Charles Historic District
9.6 out of 10, Exceptional, (42 reviews)
"The location is excellent. "
United States
McRay H.
$298 nightly
The price is $328
Sep 1 - Sep 2
Total with taxes and fees
Historic 1805 Main Street 2BR
A modern kitchen with stainless steel appliances, white cabinetry, and a brick accent wall.

14. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
$332 nightly
The price is $365
Sep 6 - Sep 7
Total with taxes and fees
Historic Main St. Customs House Upstairs Apartment
A modern living room with a spiral staircase, a brick wall, a dining area, and a gray sofa.

15. Historic Main St 2BR | Steps to Shops

Historic Main St 2BR | Steps to Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (41 reviews)
"This property has a nice renovation while keeping a lot of its original character. Very clean and comfortable beds as well. The location couldn’t be better! We really enjoyed our stay."
United States
William O.
$346 nightly
The price is $381
Sep 1 - Sep 2
Total with taxes and fees
Historic Main St 2BR | Steps to Shops
A row of multi-story buildings with commercial storefronts, including a cafe and a restaurant.

16. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (37 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
$187 nightly
The price is $206
Sep 1 - Sep 2
Total with taxes and fees
Historic Main Street Studio | Dog-Friendly
A modern kitchen with a central island, a dining area with a sofa, and a living room with a TV.

17. Main Street 2BR Apartment with Garage and Deck

Main Street 2BR Apartment with Garage and Deck
St. Charles Historic District
9.4 out of 10, Exceptional, (21 reviews)
"We loved our stay for Memorial Day weekend! It was the perfect space to unwind after a day of walking around historic Saint Charles. Our favorite spot was the back deck. Having the garage was so convenient and the space itself is really beautiful. The only thing we wish we had prepared for was a lack of basic kitchen cooking items. We bought breakfast food to cook but did not think to bring cooking oil/s&p. Would love to stay again sometime! We had a great weekend."
United States
Jennifer M.
$279 nightly
The price is $307
Sep 1 - Sep 2
Total with taxes and fees
Main Street 2BR Apartment with Garage and Deck
A cozy living room with a brick wall, a white sofa with colorful cushions, a small black table, and a potted plant.

18. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (116 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveler
$246 nightly
The price is $263
Aug 30 - Aug 31
Total with taxes and fees
Prime Loft of Main Street
A staircase with white railings and a ceiling fan.

19. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (68 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
$246 nightly
The price is $263
Aug 30 - Aug 31
Total with taxes and fees
Amazing Renovated Historic Loft on Main Street
A spacious living area with a wooden floor, a dining table with chairs, a flat-screen TV mounted on the wall, and a kitchen area with modern appliances.

20. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (187 reviews)
"It was great! Clean and great communication with host."
United States
Natalie H.
$246 nightly
The price is $263
Aug 30 - Aug 31
Total with taxes and fees
The Lofts of North Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Ann Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"A good place to take off your shoes and stay awile."
Kenneth 1-night trip
Posted less than an hour ago
Drury Plaza Hotel St. Louis Union Station

Find out more about St. Ann

Everything you need to know about St. Ann vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Ann vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Ann vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Ann vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Ann. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Ann in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $75 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Ann rentals

At Expedia, we put the best St. Ann vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Ann rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Ann vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Ann. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in St. Ann?

Yes, we give you a choice of vacation rentals where you'll be just 8.5 mi (13.7 km) from St. Louis Zoo, offering you a secluded option if you want a quiet place to stay. Our travelers say St. Ann has a good selection of restaurants and the bars. Make sure you have time to check out the baseball games and shopping during your trip.

What are some of the best vacation home rentals in St. Ann?

4BR 2BA Modern Family Home with Private Heated Inground Pool Open March 1-Nov11: This vacation home rental near St. Ann offers an outdoor pool, a fireplace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and a selection of games so you can immerse yourself in your vacation.

How many vacation rentals are there in St. Ann?

With 10 Expedia vacation rentals, you're sure to find just the right place for your St. Ann stay.

What can I see and do in St. Ann?

While exploring the area, visit family-friendly sights like St. Louis Zoo, or get outside and enjoy nature at Lou Fusz Soccer Complex. While in the area, you can also visit popular places like St. Louis Union Station and Busch Stadium.

What are vacation rentals like in St. Ann?

Vacation rentals are private properties you can stay in for several days or more in St. Ann. Vacation rentals feature extras like kitchens and laundry facilities so you'll have all the conveniences of home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of security away from shared hotel elevators and busy front desks while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a great choice for a family getaway.