St. Charles Vacation Rentals

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Our top choices for St. Charles vacation rentals

6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (1)
$230 nightly
The price is $259
Jan 8 - Jan 9
Total with taxes and fees
6th street 101 - Walk to Main St

Saint Charles 2 Bedroom Townhome by StayLage

Saint Charles 2 Bedroom Townhome by StayLage
Saint Charles
9.2 out of 10, Wonderful, (7)
"We were very happy with our experience. Everything was as advertised, all of the basics were covered for us. Great place to stay. Thanks"
United States
bill r.
$261 nightly
The price is $287
Jan 8 - Jan 9
Total with taxes and fees
Saint Charles 2 Bedroom Townhome by StayLage

Luxurious 2-Bedroom Abode with Elevated Comforts Near Main Street

Luxurious 2-Bedroom Abode with Elevated Comforts Near Main Street
Saint Charles
9.0 out of 10, Wonderful, (2)
"The overall vibe struck me as a college town apartment: the building was fine, but finishes were underwhelming. The unit itself was a little small, but workable. We had a scenario where the heater seemed to be acting up; the room actually got warmer after we shut the heat off. It was a pleasant enough stay, and served the purpose we had come for: visiting our adult children. It was a bit of a walk to get to the historic district."
United States
Greg L.
$232 nightly
The price is $256
Jan 8 - Jan 9
Total with taxes and fees
Luxurious 2-Bedroom Abode with Elevated Comforts Near Main Street

Madison House 1 -Walk to Main St

Madison House 1 -Walk to Main St
St. Charles Historic District
8.6 out of 10, Excellent, (16)
"The house was clean and well stocked, location was great, and plenty of street parking. "
United States
Brad K.
$199 nightly
The price is $224
Jan 8 - Jan 9
Total with taxes and fees
Madison House 1 -Walk to Main St

1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.6 out of 10, Good, (8)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
$199 nightly
The price is $224
Jan 8 - Jan 9
Total with taxes and fees
1st Capitol Mansion - Suite 401

The Historic Bricks on Main

The Historic Bricks on Main
St. Charles Historic District
9.0 out of 10, Wonderful, (14)
"Had a wonderful stay. Host was very responsive. Great stay in the middle of everything- so we could walk out and shop or grab a bite to eat. "
United States
Alison C.
$179 nightly
The price is $197
Jan 11 - Jan 12
Total with taxes and fees
The Historic Bricks on Main

Saint Charles White House

Saint Charles White House
Saint Charles
8.6 out of 10, Excellent, (4)
"It was great Needed towels but otherwise great"
United States
Jennifer R.
$321 nightly
The price is $321
Jan 8 - Jan 9
Total with taxes and fees
Saint Charles White House

Main Street Living! 2 Bedroom Unit right On Main!

Main Street Living! 2 Bedroom Unit right On Main!
St. Charles Historic District
9.6 out of 10, Exceptional, (34)
"Great Stay and great location! "
United States
Angela
$310 nightly
The price is $342
Jan 8 - Jan 9
Total with taxes and fees
Main Street Living! 2 Bedroom Unit right On Main!

2 Bed Townhome w/ Backyard and Laundry by StayLage

2 Bed Townhome w/ Backyard and Laundry by StayLage
Saint Charles
8.8 out of 10, Excellent, (18)
"Wish we would have had more time to stay a little longer. Will definitely stay again in the future!"
United States
Rebecca O.
$241 nightly
The price is $265
Jan 11 - Jan 12
Total with taxes and fees
2 Bed Townhome w/ Backyard and Laundry by StayLage

Spacious 2 Bedroom Townhome by StayLage

Spacious 2 Bedroom Townhome by StayLage
Saint Charles
8.0 out of 10, Very Good, (11)
"Perfect size"
United States
Barbie D.
$251 nightly
The price is $276
Jan 11 - Jan 12
Total with taxes and fees
Spacious 2 Bedroom Townhome by StayLage

Winter SALE,Cozy 2BR Chalet, Hot Tub 1.2 Acres!

Winter SALE,Cozy 2BR Chalet, Hot Tub 1.2 Acres!
Saint Charles
8.8 out of 10, Excellent, (3)
"We loved the location for our travel needs and we had everything we needed for a family of two adults and two dogs. "
United States
Leslie R.
$485 nightly
The price is $543
Jan 8 - Jan 9
Total with taxes and fees
Winter SALE,Cozy 2BR Chalet, Hot Tub 1.2 Acres!

Spacious 2-Bedroom Near Main St by StayLage

Spacious 2-Bedroom Near Main St by StayLage
St. Charles Historic District
8.8 out of 10, Excellent, (13)
"Great space! Very comfortable! "
United States
Mary H.
$232 nightly
The price is $256
Jan 8 - Jan 9
Total with taxes and fees
Spacious 2-Bedroom Near Main St by StayLage

St. Charles, MO house with Private Patio

St. Charles, MO house with Private Patio
St. Charles Historic District
8.8 out of 10, Excellent, (18)
"The responsive of our host was incredible!!We anticipate staying here again!! The location is great. And the neighbors are great.!"
United States
Tom M.
$260 nightly
The price is $287
Jan 8 - Jan 9
Total with taxes and fees
St. Charles, MO house with Private Patio

Historic 5th Street House - Fully Rehabbed # 2

Historic 5th Street House - Fully Rehabbed # 2
St. Charles Historic District
8.8 out of 10, Excellent, (11)
"Wonderful place to stay would definitely recommend "
United States
Steven S.
$210 nightly
The price is $236
Jan 11 - Jan 12
Total with taxes and fees
Historic 5th Street House - Fully Rehabbed # 2

The Great Room - fully cozy & private Townhome

The Great Room - fully cozy & private Townhome
Saint Charles
10.0 out of 10, Exceptional, (1)
"The place was beautiful and decorated well. Our experience was great and i recommend this rental. Would be nice if they honored military discount as I am a veteran. "
United States
Rodney M.
$296 nightly
The price is $296
Jan 13 - Jan 14
Total with taxes and fees
The Great Room - fully cozy & private Townhome

Victorian Gem Steps from Main St - Sleeps 9 & Pets

Victorian Gem Steps from Main St - Sleeps 9 & Pets
St. Charles Historic District
9.8 out of 10, Exceptional, (22)
"A beautiful place with Victorian charm and modern amenities! This was the perfect place for our family."
United States
Kathleen D.
$453 nightly
The price is $505
Jan 11 - Jan 12
Total with taxes and fees
Victorian Gem Steps from Main St - Sleeps 9 & Pets

3BR Historic St. Charles, MO-Walking distance to Main Street

3BR Historic St. Charles, MO-Walking distance to Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (16)
"Very clean & Great location. The host was wonderful."
United States
Anonymous traveler
$489 nightly
The price is $512
Jan 13 - Jan 14
Total with taxes and fees
3BR Historic St. Charles, MO-Walking distance to Main Street

Spacious, Beautiful St. Charles Home-Remodeled-Sleeps 10! New Patio!

Spacious, Beautiful St. Charles Home-Remodeled-Sleeps 10! New Patio!
St. Charles Historic District
9.8 out of 10, Exceptional, (55)
"We had a great time! Awesome back patio nice grill comfortable bedding "
United States
Kyle H.
$430 nightly
The price is $439
Jan 8 - Jan 9
Total with taxes and fees
Spacious, Beautiful St. Charles Home-Remodeled-Sleeps 10! New Patio!

The Olive House - Near Main Street- Fully rehabbed

The Olive House - Near Main Street- Fully rehabbed
Saint Charles
8.8 out of 10, Excellent, (9)
"Perfect location for buddies golf trip... clean comfortable house...very helpful host!"
United States
Mark H.
$310 nightly
The price is $349
Jan 8 - Jan 9
Total with taxes and fees
The Olive House - Near Main Street- Fully rehabbed

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (57)
"Great place and location. Owners were easy to work with."
United States
Cory M.
$236 nightly
The price is $252
Jan 8 - Jan 9
Total with taxes and fees
Amazing Renovated Historic Loft on Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Find out more about St. Charles

Everything you need to know about St. Charles vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Charles vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Charles in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $145 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Charles rentals

At Expedia, we put the best St. Charles vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, you can find vacation rentals near popular attractions in St. Charles, or you can choose a secluded option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in St. Charles. The live music and theater scene are some other things you might like to check out during your trip.

What are some of the best vacation rentals that St. Charles has to offer?

The St. Charles Guest House, lovely historic home, fun for families and groups: This St. Charles vacation home rental is located on a river and has a fireplace, a selection of games, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Some other top choices in St. Charles are 🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟 and Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway.

How many vacation rentals are there in St. Charles?

Expedia has 89 vacation rentals for your stay in St. Charles.

What can I see and do in St. Charles?

Katy Trail and Mississippi River are a couple of scenic spots to enjoy the outdoors, whereas Missouri Artists on Main is one of the cultural attractions. Other places in town to visit include Historic Main Street and First Missouri State Capitol Historic Site.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned accommodations you can book for several days or more in St. Charles. Vacation rentals provide amenities such as laundry facilities and kitchens to help you enjoy your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for a family getaway.