Downtown St. Louis Vacations from $363
Book a Hotel + Flight or Car together to unlock savings
Your Downtown St. Louis Vacation
A sought-after riverside neighborhood, Downtown St. Louis tempts visitors with its festivals, bars and pubs and dining. Lock in a vacation package to Downtown St. Louis and look forward to experiencing all the best bits for yourself. Some top nearby attractions to check out during your trip to Downtown St. Louis include Busch Stadium, Gateway Arch and Dome at America’s Center. Expedia will help you turn your ideal Downtown St. Louis vacation into reality, no matter your travel plans or budget.
The Latest Downtown St. Louis Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hilton Pennywell St. Louis at the Arch
Downtown St. Louis
Price was $453, price is now $363 per person
$363
per person
May 20 - May 23
found 15 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,029 reviews)
Yea but truly my wife was the star of theshow
Reviewed on Feb 23, 2026
The Wildwood Hotel
Save 100% on your flight
Price was $1,130, price is now $638 per person
$638
per person
May 20 - May 23
found 15 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,620 reviews)
Very nice, clean and there is a pool, a small gym and access to good things in the area
Reviewed on Mar 18, 2026
The Knight Center at Washington University
Price was $537, price is now $394 per person
$394
per person
May 20 - May 23
found 15 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.4/10 Exceptional! (496 reviews)
Great place to stay on campus. Extremely helpful and friendly staff you don’t typically find at the chain hotels.
Reviewed on Mar 14, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Price was $540, price is now $407 per person
$407
per person
May 20 - May 23
found 15 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,065 reviews)
Super close to the center. Great Breakfast. Clean room and very friendly staff. However, it would be most likely cheaper to buy breakfast the day off then prepay while booking. I got vouchers because I paid for breakfast in advance but could see what my bill would have been and I paid more when booking the room.
Reviewed on Mar 16, 2026
Where to stay in Downtown St. Louis
Find the best Downtown St. Louis areas and neighborhoods for the activities you enjoy most. Learn more about Downtown St. Louis
Clayton
1 out of top 10 points of interest in this area
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Downtown St. Louis Hotel Deals
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $189 total per night from Mar 29 to Mar 30
$189 total
Mar 29 - Mar 30
Total with taxes and fees
9.4/10 Exceptional! (3,344 reviews)
The room was great with a view of the Arch...very comfortable. Very convenient location. The food buffets were good to have...average/above average. The drink tickets were appreciated. Staff was friendly.
Reviewed on Mar 20, 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $188 total per night from Apr 2 to Apr 3
$188 total
Apr 2 - Apr 3
Total with taxes and fees
8.4/10 Very Good! (3,978 reviews)
Other than the amount for parking we had a great stay
Reviewed on Mar 19, 2026
Live by Loews - St.Louis
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $177 total per night from Apr 5 to Apr 6
$177 total
Apr 5 - Apr 6
Total with taxes and fees
9.4/10 Exceptional! (1,127 reviews)
Clean room, helpful staff. Easy check-in and parking
Reviewed on Mar 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Downtown St. Louis
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Dome at America’s Center
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's acclaimed art scene and fascinating museums.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
Lemp Haunted Neighborhood Walking Tour
$30
per adult
84% of travellers recommend
St. Louis Premium Driving Tour with Boat Ride & Arch
$174
per adult
100% of travellers recommend
Explore a world of travel with Expedia
- St. Louis Hotels
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- Gateway Arch
- Gateway Arch National Park
- Old Courthouse
- Busch Stadium
- St. Louis Vacations
- Kiener Plaza
- Wainwright Building
- Cardinals Hall of Fame and Museum
- Gateway Arch Visitor Center
- Federal Reserve Bank of St. Louis
- National Blues Museum
- Old Post Office
- Eugene Field House & St. Louis Toy Museum
- America's Center Convention Complex
- St. Louis City Hall
- Dome at America’s Center
- Eads Bridge
- Laclede's Landing Vacations
- St. Mary of Victories Catholic Church
- City Museum
- Central Public Library
- Christ Church Cathedral
- Citygarden
- Peabody Opera House
- Campbell House Museum
- Enterprise Center
- Anheuser-Busch Brewery
- St. Louis Aquarium at Union Station
- St. Louis Union Station
- Visit St. Louis
- St. Louis Union Station Mini Golf
- Meeting of the Waters Fountain
- Soulard Farmer's Market
- Car rentals near St. Louis
- Car rentals near Gateway Arch National Park
- Car rentals near Kiener Plaza
- Car rentals near Gateway Arch
- Car rentals near Busch Stadium
- Car rentals near America's Center Convention Complex
- Car rentals near Dome at America’s Center
- Car rentals near Laclede's Landing
- Car rentals near Enterprise Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.