Downtown St. Louis Vacations from $418
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Your Downtown St. Louis Vacation
A sought-after riverside neighborhood, Downtown St. Louis tempts visitors with its festivals, bars and pubs and dining. Lock in a vacation package to Downtown St. Louis and look forward to experiencing all the best bits for yourself. Some top nearby attractions to check out during your trip to Downtown St. Louis include Busch Stadium, Gateway Arch and Dome at America’s Center. Expedia will help you turn your ideal Downtown St. Louis vacation into reality, no matter your travel plans or budget.
The Latest Downtown St. Louis Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The West End
Central West End
Price was $503, price is now $418 per person
$418
per person
Dec 18 - Dec 21
found 21 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to St. Louis (STL)
16.8/10 Exceptional! (386 reviews)
Everything was great. The host and staff were extremely friendly and helpful. Room was amazing and the perfect size for a nice relaxing weekend. We will return. Highly recommend.
Reviewed on Nov 17, 2025
The Knight Center at Washington University
Price was $625, price is now $531 per person
$531
per person
Feb 8 - Feb 10
found 21 hours ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
18.8/10 Exceptional! (422 reviews)
One of the absolute best places I’ve ever stayed. Facilities were immaculate and I felt safe walking around. Beautiful campus!
Reviewed on Nov 16, 2025
Hampton Inn By Hilton St Louis Airport
Woodson Terrace
Price was $569, price is now $493 per person
$493
per person
Feb 8 - Feb 10
found 21 hours ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
8.8/10 Excellent! (81 reviews)
Overall, this was the best stay I've had in St. Louis in a very long time the staff were nice. Hotel was very clean, bed super comfortable. And great breakfast option for people that don't eat pork.
Reviewed on Oct 26, 2025
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Price was $579, price is now $507 per person
$507
per person
Feb 8 - Feb 10
found 21 hours ago
Roundtrip flight included
Boston (BOS) to St. Louis (STL)
17.6/10 Exceptional! (1,019 reviews)
Room was very clean, we really appreciated Wesley and Nyla’s help checking in!
Reviewed on Nov 15, 2025
Where to stay in Downtown St. Louis
Find the best Downtown St. Louis areas and neighborhoods for the activities you enjoy most. Learn more about Downtown St. Louis
Clayton
1 out of top 10 points of interest in this area
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Downtown St. Louis Hotel Deals
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $120 total per night from Nov 23 to Nov 24
$120 total
Nov 23 - Nov 24
Total with taxes and fees
8.6/10 Excellent! (1,092 reviews)
Room was very clean, common areas could use new carpet. The hotel staff was extremely helpful and friendly. Parking was HIGH!! $57/per night after tax and before tip. Hotel felt very old European. This survey asked me about the ‘free breakfast’….that is the first Ive heard of a ‘free breakfast’. ...
Reviewed on Nov 12, 2025
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $129 total per night from Dec 7 to Dec 8
$129 total
Dec 7 - Dec 8
Total with taxes and fees
8.4/10 Very Good! (3,997 reviews)
Everything was great except the delay of the elevators. I believe half of them were working and the hotel was very busy. After checkin I waited at least 15 minutes for an elevator to get to my room.
Reviewed on Nov 10, 2025
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $161 total per night from Nov 23 to Nov 24
$161 total
Nov 23 - Nov 24
Total with taxes and fees
9.4/10 Exceptional! (3,243 reviews)
Beds were comfortable and the rooms were clean. Very friendly staff.
Reviewed on Nov 16, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Downtown St. Louis
Gateway Arch
4.5/5(2,511 reviews)
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Busch Stadium
4.5/5(1,469 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Horseshoe St. Louis Casino
4/5(14 reviews)
Why not roll the dice with a visit to Horseshoe St. Louis Casino during your time in St. Louis? Experience the area's acclaimed art scene or attend a baseball game.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$26
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
$32
per adult
100% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
$27
per adult
84% of travellers recommend
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- Gateway Arch
- Gateway Arch National Park
- Old Courthouse
- Busch Stadium
- St. Louis Vacations
- Kiener Plaza
- Wainwright Building
- Cardinals Hall of Fame and Museum
- Gateway Arch Visitor Center
- Federal Reserve Bank of St. Louis
- National Blues Museum
- Old Post Office
- Eugene Field House & St. Louis Toy Museum
- America's Center Convention Complex
- St. Louis City Hall
- Dome at America’s Center
- Eads Bridge
- Laclede's Landing Vacations
- St. Mary of Victories Catholic Church
- City Museum
- Central Public Library
- Christ Church Cathedral
- Citygarden
- Peabody Opera House
- Campbell House Museum
- Enterprise Center
- Anheuser-Busch Brewery
- St. Louis Aquarium at Union Station
- St. Louis Union Station
- Visit St. Louis
- St. Louis Union Station Mini Golf
- Meeting of the Waters Fountain
- Soulard Farmer's Market
- Car rentals near St. Louis
- Car rentals near Gateway Arch National Park
- Car rentals near Kiener Plaza
- Car rentals near Gateway Arch
- Car rentals near Busch Stadium
- Car rentals near America's Center Convention Complex
- Car rentals near Dome at America’s Center
- Car rentals near Laclede's Landing
- Car rentals near Enterprise Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.