Downtown St. Louis Vacations from $540
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Your Downtown St. Louis Vacation
A sought-after riverside neighborhood, Downtown St. Louis tempts visitors with its festivals, bars and pubs and dining. Lock in a vacation package to Downtown St. Louis and look forward to experiencing all the best bits for yourself. Some top nearby attractions to check out during your trip to Downtown St. Louis include Busch Stadium, Gateway Arch and Dome at America’s Center. Expedia will help you turn your ideal Downtown St. Louis vacation into reality, no matter your travel plans or budget.
The Latest Downtown St. Louis Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Country Inn & Suites by Radisson, St. Charles Historic District
St. Charles Historic District
$703
per person
Nov 17 - Nov 23
found 1 day ago
Roundtrip flight included
New York (NYC) to St. Louis (STL)
9.4/10 Exceptional! (1,098 reviews)
Excellent location. Good parking. Clean rooms.
Reviewed on Oct 14, 2026
Where to stay in Downtown St. Louis
Find the best Downtown St. Louis areas and neighborhoods for the activities you enjoy most. Learn more about Downtown St. Louis
Clayton
1 out of top 10 points of interest in this area
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Downtown West
2 out of top 10 points of interest in this area
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Downtown St. Louis Hotel Deals
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$134 nightly
$158 total
Oct 30 - Oct 31
Total with taxes and fees
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
$158 total
Oct 25 - Oct 26
Total with taxes and fees
9.6/10 Exceptional! (3,799 reviews)
"Car broke"
Reviewed on Oct 14, 2026
Live by Loews - St.Louis
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
$189 total
Oct 18 - Oct 19
Total with taxes and fees
9.4/10 Exceptional! (1,347 reviews)
"The area was nice and in the center of what we wanted to do for the weekend!!"
Reviewed on Oct 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Downtown St. Louis attractions
Gateway Arch
9.2/10 (9,046 reviews)
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Photo by Carl Guttovz
Busch Stadium
9.4/10 (4,850 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
Dome at America’s Center
8.4/10 (1,229 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art scene.
Photo by St. Louis Convention & Visitors Commission
Gateway Arch National Park
8.6/10 (4 reviews)
This central park houses the Gateway Arch, Museum of Westward Expansion and Old Courthouse, and is a popular starting point for exploring the Mississippi River.
Old Courthouse
9.0/10 (6 reviews)
Some of America’s landmark legal battles, including the Dred Scott and Virginia Minor cases, were fought in this historic building in St. Louis.
National Blues Museum
Through live performances on a state-of-the-art stage and an array of films, talks and listening booths, this museum will teach you about the blues.
America's Center Convention Complex
8.8/10 (306 reviews)
Learn about the events happening at America's Center Convention Complex during your trip to St. Louis. Experience the area's acclaimed art scene and great live music.
Ballpark Village
You can enjoy retail therapy at Ballpark Village during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
Things to do
StL's Signature "Sights and Bites" - Private Tour in St. Louis
$175
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
100% of travellers recommend
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
$15
per traveler
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- Samuel Cupples House
- Wainwright Building
- Washington Avenue Historic District
- Dome at America’s Center
- Cathedral Basilica of St. Louis
- America's Center Convention Complex
- Gateway Arch National Park
- Eugene Field House & St. Louis Toy Museum
- Kiener Plaza
- Visit St. Louis
- St. Louis Cathedral
- Magic House - St. Louis Children's Museum
- Central Public Library
- Chaifetz Arena
- Fox Theater
- St. Louis Science Center
- St. Louis Union Station Mini Golf
- Gateway Arch Visitor Center
- Jewel Box
- St. Louis Vacations
- City Museum
- Meeting of the Waters Fountain
- St. Louis City Hall
- Christ Church Cathedral
- The MOTO Museum
- Campbell House Museum
- St. Mary of Victories Catholic Church
- Grant's Farm
- Bruno David Gallery
- St. Alphonsus Liguori Catholic Church
- St. Louis Aquarium at Union Station
- The Muny Theater
- National Blues Museum
- Where to stay in St. Louis
- Citygarden Sculpture Park
- Soulard Farmer's Market
- Missouri Botanical Gardens and Arboretum
- Museum at the Gateway Arch
- Enterprise Center
- St. Louis Art Museum
- St. Louis Zoo
- Old Post Office
- Citygarden
- Eads Bridge
- Gateway Arch
- Busch Stadium
- Old Courthouse
- Horseshoe St. Louis Casino
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.