Downtown St. Louis Vacations from $276
Book a Hotel + Flight or Car together to unlock savings
Your Downtown St. Louis Vacation
A sought-after riverside neighborhood, Downtown St. Louis tempts visitors with its festivals, bars and pubs and dining. Lock in a vacation package to Downtown St. Louis and look forward to experiencing all the best bits for yourself. Some top nearby attractions to check out during your trip to Downtown St. Louis include Busch Stadium, Gateway Arch and Dome at America’s Center. Expedia will help you turn your ideal Downtown St. Louis vacation into reality, no matter your travel plans or budget.
The Latest Downtown St. Louis Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
Save 100% on your flight
Price was $553, price is now $276 per person
$276
per person
Apr 13 - Apr 17
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Great place to stay! We arrived later at night around 11pm and the front desk gal working at that time was wonderful. Nice, quiet, clean and in a very nice area.
Reviewed on Feb 27, 2026
Crowne Plaza St. Louis Airport by IHG
Save 100% on your flight
Price was $500, price is now $340 per person
$340
per person
Apr 13 - Apr 17
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8/10 Very Good! (1,002 reviews)
Everything was amazing but parking was not enough. We had to park on ur median. Rooms are older but still nice. Good area. Friendly staff.
Reviewed on Feb 21, 2026
Hotel Saint Louis, Autograph Collection
Downtown St. Louis
Save 100% on your flight
Price was $663, price is now $455 per person
$455
per person
Apr 13 - Apr 17
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.8/10 Excellent! (458 reviews)
Not the best and not the
Reviewed on Feb 24, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Save 100% on your flight
Price was $483, price is now $336 per person
$336
per person
Apr 13 - Apr 17
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8.8/10 Excellent! (1,022 reviews)
We enjoyed the unique concept of the art gallery. I do wish room service were an option. We were so exhausted once we arrived, and had hoped to stay in for dinner. The frosted glass door on the bathroom also created complications, as an earlier riser couldn't begin getting ready in the morning without turning on lights for those still sleeping.
Reviewed on Mar 2, 2026
Home2 Suites by Hilton St. Louis Downtown
Downtown West
Price was $383, price is now $281 per person
$281
per person
Apr 13 - Apr 17
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
8/10 Very Good! (567 reviews)
Valet parking only and only one attendant. Valet doesn’t start until 7am, so you don’t have access to your car until then.
Reviewed on Mar 2, 2026
Where to stay in Downtown St. Louis
Find the best Downtown St. Louis areas and neighborhoods for the activities you enjoy most. Learn more about Downtown St. Louis
Clayton
1 out of top 10 points of interest in this area
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Downtown St. Louis Hotel Deals
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Mar 9 to Mar 10
$158 total
Mar 9 - Mar 10
Total with taxes and fees
9.4/10 Exceptional! (3,343 reviews)
The staff is extremely nice! The breakfast and happy food was great! Close to the arch and ballpark village.
Reviewed on Mar 3, 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $188 total per night from Mar 28 to Mar 29
$188 total
Mar 28 - Mar 29
Total with taxes and fees
8.4/10 Very Good! (4,002 reviews)
Great view from our room! We loved our stay!
Reviewed on Mar 2, 2026
Live by Loews - St.Louis
799 Clark ave St. Louis MO
$149 nightly
The price is $177 total per night from Apr 3 to Apr 4
$177 total
Apr 3 - Apr 4
Total with taxes and fees
9.4/10 Exceptional! (1,128 reviews)
Clean, stand staff was great
Reviewed on Mar 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Downtown St. Louis
Busch Stadium
4.5/5(1,469 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
4.5/5(2,511 reviews)
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Dome at America’s Center
4/5(530 reviews)
Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and great live music.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
$24
per adult
St. Louis Premium Small Group Tour With Arch & River Cruise
$169
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
$30
per adult
84% of travellers recommend
Explore a world of travel with Expedia
- St. Louis Hotels
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- Gateway Arch
- Gateway Arch National Park
- Old Courthouse
- Busch Stadium
- St. Louis Vacations
- Kiener Plaza
- Wainwright Building
- Cardinals Hall of Fame and Museum
- Gateway Arch Visitor Center
- Federal Reserve Bank of St. Louis
- National Blues Museum
- Old Post Office
- Eugene Field House & St. Louis Toy Museum
- America's Center Convention Complex
- St. Louis City Hall
- Dome at America’s Center
- Eads Bridge
- Laclede's Landing Vacations
- St. Mary of Victories Catholic Church
- City Museum
- Central Public Library
- Christ Church Cathedral
- Citygarden
- Peabody Opera House
- Campbell House Museum
- Enterprise Center
- Anheuser-Busch Brewery
- St. Louis Aquarium at Union Station
- St. Louis Union Station
- Visit St. Louis
- St. Louis Union Station Mini Golf
- Meeting of the Waters Fountain
- Soulard Farmer's Market
- Car rentals near St. Louis
- Car rentals near Gateway Arch National Park
- Car rentals near Kiener Plaza
- Car rentals near Gateway Arch
- Car rentals near Busch Stadium
- Car rentals near America's Center Convention Complex
- Car rentals near Dome at America’s Center
- Car rentals near Laclede's Landing
- Car rentals near Enterprise Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.