
Downtown St. Louis Vacations from $275
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Your Downtown St. Louis Vacation
A sought-after riverside neighborhood, Downtown St. Louis tempts visitors with its festivals, bars and pubs and dining. Lock in a vacation package to Downtown St. Louis and look forward to experiencing all the best bits for yourself. Some top nearby attractions to check out during your trip to Downtown St. Louis include Busch Stadium, Gateway Arch and Dome at America’s Center. Expedia will help you turn your ideal Downtown St. Louis vacation into reality, no matter your travel plans or budget.
The Latest Downtown St. Louis Vacation Packages

The Wildwood Hotel
Reviewed on Dec 29, 2025

Hampton Inn By Hilton St Louis Airport
Reviewed on Dec 22, 2025

The Knight Center at Washington University
Reviewed on Dec 27, 2025

Hilton Garden Inn Chesterfield
Reviewed on Dec 22, 2025

Ameristar Casino Resort and Spa
Reviewed on Dec 28, 2025
Where to stay in Downtown St. Louis

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Downtown St. Louis Hotel Deals

Hyatt Regency St. Louis at The Arch
Everything was great.
Reviewed on Dec 28, 2025

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Breakfast area was small and crowded - did not help to have children and some teenagers on their own and not exactly being quiet.
Reviewed on Dec 19, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Great stay. Superb staff. Rooms were beautiful except bathroom very dated and the corners were not very clean
Reviewed on Dec 25, 2025
Discover the most popular places to visit in Downtown St. Louis

Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Horseshoe St. Louis Casino
Why not roll the dice with a visit to Horseshoe St. Louis Casino during your time in St. Louis? Experience the area's great live music or attend a baseball game.
Things to do

St. Louis Ghost Tour: Sinister Sins & Shadows

Lemp Haunted Neighborhood Walking Tour

St. Louis Premium Driving Tour with Boat Ride & Arch
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- Gateway Arch
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- St. Louis Vacations
- Kiener Plaza
- Wainwright Building
- Cardinals Hall of Fame and Museum
- Gateway Arch Visitor Center
- Federal Reserve Bank of St. Louis
- National Blues Museum
- Old Post Office
- Eugene Field House & St. Louis Toy Museum
- America's Center Convention Complex
- St. Louis City Hall
- Dome at America’s Center
- Eads Bridge
- Laclede's Landing Vacations
- St. Mary of Victories Catholic Church
- City Museum
- Central Public Library
- Christ Church Cathedral
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- Anheuser-Busch Brewery
- St. Louis Aquarium at Union Station
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- Visit St. Louis
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- Meeting of the Waters Fountain
- Soulard Farmer's Market
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