St. Anthony Vacations from $409

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The Latest St. Anthony vacation packages

Price found within the past 48 hours. Click for updated prices.
AmericInn by Wyndham Ankeny/Des Moines

AmericInn by Wyndham Ankeny/Des Moines

3 out of 5
Price was $467, price is now $409 per person
$409
per person
Jan 8 - Jan 11
found 24 hours ago
Roundtrip flight included
Los Angeles (LAX) to Des Moines (DSM)
8/10 Very Good! (818 reviews)
The room was nice. Staff was very pleasant.

Reviewed on Nov 23, 2025

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
Downtown Des Moines
Price was $614, price is now $514 per person
$514
per person
Jan 8 - Jan 11
found 24 hours ago
Roundtrip flight included
Los Angeles (LAX) to Des Moines (DSM)
9.6/10 Exceptional! (1,037 reviews)
This is our second time staying here. It feels like a 5 star hotel. The details in the decor are unique and well designed. The bed and bedding is comfortable. I love the lobby, large and spacious with lots of seating options for gatherings small or large. Great restaurant, Proudfoot and Bird with a bar that has great happy hour from 2-6 daily. The happy hour has great food options, not so much for drinks on special. The HOBNob restaurant for breakfast is ok, but service there is slow. Will definitely stay there again. Great price for the quality of the hotel.

Reviewed on Dec 6, 2025

Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown

2.5 out of 5
Downtown Des Moines
Price was $584, price is now $496 per person
$496
per person
Jan 8 - Jan 11
found 24 hours ago
Roundtrip flight included
Los Angeles (LAX) to Des Moines (DSM)
8.6/10 Excellent! (1,001 reviews)
Everything was amazing except our TV had only one channel and toliet would always run.

Reviewed on Nov 29, 2025

Cobblestone Inn & Suites - Winterset, IA

Cobblestone Inn & Suites - Winterset, IA

2.5 out of 5
Price was $531, price is now $451 per person
$451
per person
Jan 8 - Jan 11
found 24 hours ago
Roundtrip flight included
Los Angeles (LAX) to Des Moines (DSM)
9.2/10 Wonderful! (708 reviews)
We found a bug on our bed, it bite Russ.

Reviewed on Nov 5, 2025

Hilton Des Moines Downtown

Hilton Des Moines Downtown

3.5 out of 5
Downtown Des Moines
Price was $716, price is now $625 per person
$625
per person
Jan 8 - Jan 11
found 24 hours ago
Roundtrip flight included
Los Angeles (LAX) to Des Moines (DSM)
9/10 Wonderful! (1,000 reviews)
Clean and quiet room, excellent restaurant, and very accommodating staff.

Reviewed on Nov 1, 2025

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St. Anthony Hotel Deals

Comfort Inn Marshalltown South

Comfort Inn Marshalltown South

2.5 out of 5
2613 S Center St Marshalltown IA
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Jan 3 to Jan 4
$76 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
8.4/10 Very Good! (345 reviews)
Clan room and helpful staff and great location and the breakfast was great and the pool was relaxing and fun

Reviewed on Nov 8, 2025

Comfort Inn Marshalltown South
Quality Inn & Suites Ames Conference Center Near ISU Campus

Quality Inn & Suites Ames Conference Center Near ISU Campus

2.5 out of 5
2601 E 13th St Ames IA
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $74 total per night from Dec 14 to Dec 15
$74 total
Dec 14 - Dec 15
Total with taxes and fees
6.8/10 (461 reviews)
Pool and breakfast area was very nice.

Reviewed on Nov 1, 2025

Quality Inn & Suites Ames Conference Center Near ISU Campus
Comfort Inn Story City

Comfort Inn Story City

2.5 out of 5
425 Timberland Dr Story City IA
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $90 total per night from Jan 2 to Jan 3
$90 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
8.6/10 Excellent! (383 reviews)
The staff was very friendly and helpful. I loved that they decorated the lobby and elevator. Definitely made my stay feel comfortable ☺️

Reviewed on Nov 5, 2025

Comfort Inn Story City
See all 43 properties in St. Anthony
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best St. Anthony Vacation Packages

St. Anthony Essential Information

Language
English
Currency
U.S dollars

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Frequently asked questions

How much does a St. Anthony vacation package cost?
You'll find cheap prices from $409 on Expedia for your St. Anthony escape. However, a range of factors like the season, length of stay and your choice of hotel will influence how much your vacation to St. Anthony costs.
What are the cheapest months to go to St. Anthony?
You can generally find lower rates and better availability in November, December and January. Explore our cheap St. Anthony vacation packages and you could land some great off-season deals.
How many days is enough for St. Anthony?
The ideal duration of your St. Anthony vacation depends on what you'd like to do. Usually, a few days to a week will give you time to go to all the top sights and discover some hidden gems along the way.
How to find the best St. Anthony package deals?
Landing a cheap St. Anthony package deal is easy with Expedia. After you've entered your trip dates and destination under our "Packages" tab, set your maximum budget, apply a couple of filters and browse what's available. You can customize your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most affordable St. Anthony package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a St. Anthony vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking hotels and flights individually. Better still, you can customize your St. Anthony escape to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Browse our great deals to see how much you can save.
When to book a vacation package to St. Anthony?
Secure incredible discounts by reserving your flights in advance with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for an impromptu St. Anthony adventure.
Does Expedia offer Book Now, Pay Later St. Anthony vacation packages?
If you're like us, you love traveling but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can spread the cost of your St. Anthony trip over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up cheap vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.