A city skyline reflected in a calm body of water, a bridge, and a sunset sky.

Uptown Central Vacations from $604

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Your Uptown Vacation

Book a customized vacation package to Uptown and experience the charms of this neighborhood from dawn till dusk. From its shopping and nature to its unique personality and vibe, there are plenty of fabulous reasons to visit Uptown. Your trip to Uptown wouldn't be complete without exploring big-name attractions nearby such as San Antonio Zoo and Aquarium, San Antonio Botanical Gardens and Marion Koogler McNay Art Museum. Whatever your travel plans or the size of your budget, booking your perfect Uptown vacation is easy with Expedia.

The Latest Uptown Central Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • A riverside courtyard with outdoor seating, a brick building with multiple windows, and a bridge in the background.
    Jan 28 - Feb 1

    Club Wyndham Riverside Suites + Flight

    Downtown San Antonio
    4 nights
    3.5 star property
    7.6/10 - Good (94 reviews)
    "There were shops and food nearby on the riverwalk and elsewhere. Have no idea if the place was pet friendly as I am not a pet owner."
    Reviewed May 7, 2026
    Roundtrip • Minneapolis (MSP) - San Antonio (SAT)
    MSP - AUS • Nonstop AUS - MSP • 1 stop
    $767
    $604
    per traveler
    found 9 hours ago
    Club Wyndham Riverside Suites
  • A patio area with outdoor seating, a fire feature, and a view of a residential building.
    Jan 14 - Jan 20

    WorldMark New Braunfels + Flight

    Gruene
    6 nights
    3.0 star property
    9.6/10 - Exceptional (220 reviews)
    "This location was perfect for our purpose, a small family reunion with our 94 year old aunt. The facility had an almost new feel to it. The facility provided enough space for my wife, two of our daughters ( one spouse), and one adult granddaughter. Neither Greune or New Braunfels is where I would choose to visit without a family purpose but the visit was enjoyable and WorldMark added to that joy."
    Reviewed November 4, 2026
    Roundtrip • Boston (BOS) - San Antonio (SAT)
    BOS - SAT • Nonstop SAT - BOS • Nonstop
    $1,036
    $782
    per traveler
    found 1 day ago
    WorldMark New Braunfels
  • A modern interior with a curved seating area, a staircase, and greenery.
    Dec 17 - Dec 21

    Sítio El Tropicano + Flight

    Downtown San Antonio
    4 nights
    4.5 star property
    Roundtrip • Boston (BOS) - San Antonio (SAT)
    BOS - SAT • Nonstop SAT - BOS • Nonstop
    $1,156
    $880
    per traveler
    found 1 day ago
    Sítio El Tropicano
  • An outdoor cafe area with tables and chairs, a sign for OSTRA, and balconies with railings.
    Jan 14 - Jan 20

    Mokara Hotel & Spa San Antonio + Flight

    Downtown San Antonio
    6 nights
    4.5 star property
    9.6/10 - Exceptional (1,001 reviews)
    Roundtrip • Boston (BOS) - San Antonio (SAT)
    BOS - SAT • Nonstop SAT - BOS • Nonstop
    $1,563
    $1,230
    per traveler
    found 1 day ago
    Mokara Hotel & Spa San Antonio
  • A wooden deck with a table and two chairs, overlooking a river and city buildings.
    Jan 14 - Jan 20

    Inn on the Riverwalk + Flight

    Downtown San Antonio
    6 nights
    3.5 star property
    9.4/10 - Exceptional (238 reviews)
    "Nice balcony that's shared which you can't see in pics. Bed is firm but comfortable. Room is really small but just right if you using it to sleep in for 2 people. It's an older building but was very pleasant to stay in and seems to be really well insulated,the only sound you hear is if someone from the next room is going in or out their door."
    Reviewed October 30, 2026
    Roundtrip • Boston (BOS) - San Antonio (SAT)
    BOS - SAT • Nonstop SAT - BOS • Nonstop
    $943
    $787
    per traveler
    found 1 day ago
    Inn on the Riverwalk

Where to stay in Uptown Central

Find the best Uptown Central areas and neighborhoods for the activities you enjoy most. Learn more about Uptown Central
Learn more about Uptown Central
A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

A cityscape with a prominent tower, a large body of water, and a sunset.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

A historic stone building with a large wooden door, arched windows, and ornate columns.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

Discover the most popular places to visit in Uptown Central

A large, abstract sculpture with a flowing design, set against a dramatic sky.
Photo by Sarah C.
Open Photo by Sarah C.

North Star Mall

8.8/10 (1,193 reviews)
You can enjoy retail therapy at North Star Mall during your visit to San Antonio. Experience the great live music and acclaimed theater scene in this walkable area.
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What to do near Uptown Central

San Antonio: Fredericksburg Wineries Day Trip with Tastings

San Antonio: Fredericksburg Wineries Day Trip with Tastings

$179
per adult
100% of travelers recommend
San Antonio: Fredericksburg Wineries Day Trip with Tastings
See all activities near Uptown Central

Uptown Central Hotel Deals

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
2.5 star property
Uptown Central
9.0 out of 10, Wonderful, (2,383 reviews)
"We had a great stay. The staff even went the extra mile when my son lost his ID. It was a great rate and I was pleasantly surprised how well maintained everything is. Will stay here again"
$79 nightly
The price is $94
Nov 12 - Nov 13
Total with taxes and fees
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.