Uptown Vacations from $518

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Your Uptown Vacation

Book a customized vacation package to Uptown and experience the charms of this neighborhood from dawn till dusk. From its shopping and nature to its unique personality and vibe, there are plenty of fabulous reasons to visit Uptown. Your trip to Uptown wouldn't be complete without exploring big-name attractions nearby such as San Antonio Zoo and Aquarium, San Antonio Botanical Gardens and Marion Koogler McNay Art Museum. Whatever your travel plans or the size of your budget, booking your perfect Uptown vacation is easy with Expedia.

The Latest Uptown Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Tx Home Group- San Antonio

Tx Home Group- San Antonio

Midtown
$518
per person
Oct 19 - Oct 24
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Antonio (SAT)
7.8/10 Good! (10 reviews)
Hotel Contessa

Hotel Contessa

Downtown San Antonio
Save 100% on your flight
$691
per person
Oct 19 - Oct 24
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Antonio (SAT)
9/10 Wonderful! (3,768 reviews)
The St. Anthony, A Luxury Collection Hotel, San Antonio

The St. Anthony, A Luxury Collection Hotel, San Antonio

Downtown San Antonio
Save 100% on your flight
$935
per person
Oct 19 - Oct 24
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Antonio (SAT)
8.8/10 Excellent! (1,004 reviews)
Great staycation for us! Had an amazing day at the pool. Room was gorgeous and the bedding was so comfortable! Highly recommend staying here!! We will be back

Reviewed on Aug 16, 2026

Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

Far West Side
Save 100% on your flight
$1,207
per person
Oct 19 - Oct 24
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Antonio (SAT)
8.8/10 Excellent! (1,003 reviews)
Hotel Gibbs Downtown Riverwalk

Hotel Gibbs Downtown Riverwalk

Downtown San Antonio
$633
per person
Oct 19 - Oct 24
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to San Antonio (SAT)
9/10 Wonderful! (2,122 reviews)
Great hotel. Great staff. Great food & wine! That you all had a wonderful time!

Reviewed on Aug 19, 2026

Where to stay in Uptown

Find the best Uptown areas and neighborhoods for the activities you enjoy most. Learn more about Uptown
A boat tour on a canal with a bridge in the background.

Downtown San Antonio

5 out of top 10 points of interest in this area

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Find hotels in Downtown San Antonio
An old church with a bell tower and arches, surrounded by greenery and a stone structure.

Far West Side

1 out of top 10 points of interest in this area

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Find hotels in Far West Side
A cityscape with a prominent tower, a large body of water, and a sunset.

Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and Cinemark San Antonio 16.

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A nighttime amusement park with roller coasters, a bridge, and a full moon.

La Cantera District

2 out of top 10 points of interest in this area

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Find hotels in La Cantera District
A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Dub Farris Athletic Complex.

Find hotels in Northwest Side

Uptown Hotel Deals

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

143 NE Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
$80 nightly
$95 total
Aug 23 - Aug 24
Total with taxes and fees
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport

95 NE Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
$114 nightly
$135 total
Aug 24 - Aug 25
Total with taxes and fees
Drury Plaza Hotel San Antonio Airport
Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport

8818 Jones Maltsberger Rd San Antonio TX
Fully refundableReserve now, pay when you stay
$85 nightly
$101 total
Aug 30 - Aug 31
Total with taxes and fees
Wyndham Garden San Antonio Airport
See all 6,276 properties in Uptown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations
Golf Vacations
Golf Vacations
Luxury Vacations
Luxury Vacations
Romantic Vacations
Romantic Vacations
Ski Vacations
Ski Vacations
Gay Friendly Vacations
LGBTQ Friendly Vacations
LGBTQ Friendly Vacations
Adventure Vacations
Adventure Vacations
Vacations in Month
Where to go when
Where to go when
Honeymoon Vacations
Honeymoon Vacations
Mountain Vacations
Mountain Vacations
Fishing Vacations
Fishing Vacations
Adults Only Vacations
Adults Only Vacations
Waterpark Vacations
Waterpark Vacations
Scuba Diving Vacations
Scuba Diving Vacations
Yoga Vacations
Yoga Vacations
Cheap Vacations
Cheap Vacations
Solo Vacations
Solo Vacations

Stay near popular Uptown attractions

A large, abstract sculpture with a flowing design, set against a dramatic sky.
Photo by Sarah C.

North Star Mall

8.8/10 (1,193 reviews)
You can enjoy retail therapy at North Star Mall during your visit to San Antonio. Experience the great live music and lively festivals in this walkable area.
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An art gallery with abstract paintings on the walls and a bench in the center.

Marion Koogler McNay Art Museum

8.6/10 (139 reviews)
You can spend time studying the exhibits at Marion Koogler McNay Art Museum in San Antonio. Experience the great live music and acclaimed theater scene in this walkable area.
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Alamo Quarry Market

8.6/10 (23 reviews)
You can do some window-shopping at Alamo Quarry Market during your stay in San Antonio. Experience the acclaimed art scene or attend a sporting event in this walkable area.
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McAllister Park

10.0/10 (1 review)
After visiting McAllister Park, make a plan to see the other sights and activities in San Antonio. Discover the top-notch restaurants and lively festivals in this walkable area.
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Quarry Golf Club

10.0/10 (1 review)
Enjoy a round of golf in San Antonio at Quarry Golf Club. Experience the acclaimed theater scene and great live music in this walkable area.
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Ice & Golf Center at Northwoods

You can take time to visit Ice & Golf Center at Northwoods during your travels to San Antonio. Amble around this family-friendly area's riverfront or attend a sporting event.
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Bowlero Thousand Oaks

You can take time to visit Bowlero Thousand Oaks during your travels to San Antonio.
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Toyota Field

Catch an event at Toyota Field during your trip to San Antonio.
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Things to do

Picture 5 for Activity San Antonio: Six Flags Fiesta Texas Admission Ticket

San Antonio: Six Flags Fiesta Texas Admission Ticket

$49
per adult
80% of travellers recommend
San Antonio: Six Flags Fiesta Texas Admission Ticket
San Antonio: Discovery Tour at Natural Bridge Caverns

San Antonio: Discovery Tour at Natural Bridge Caverns

$38
per adult
98% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
San Antonio: Botanical Garden Admission Ticket

San Antonio: Botanical Garden Admission Ticket

$18
per adult
100% of travellers recommend
San Antonio: Botanical Garden Admission Ticket
See all activities in San Antonio
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.