A clear stream flowing over rocks with surrounding dense forest.
Photo by Martin Tucker
Open Photo by Martin Tucker

Wayne County Vacations & Trips from $681

Book a Hotel + Flight or Car together to unlock savings

Your Wayne County Vacation

When wanderlust beckons, answer it with a vacation package to Wayne County. Get set to enjoy golfing, family-friendly attractions, nature, and more in this vibrant destination. During your trip to Wayne County, you'll want to tour a few of its leading cities. What shouldn't you miss? Clifton. Stop dreaming and start packing, because your Wayne County vacation is just a few clicks away with Expedia.

Top destinations in Wayne County

The Latest Wayne County Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Dec 15 - Dec 18

    Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals + Flight

    Tuscumbia
    3 nights
    2.0 star property
    8.2/10 - Very good (1,002 reviews)
    Roundtrip • Chicago (CHI) - Muscle Shoals (MSL)
    ORD - MSL • 1 stop MSL - ORD • 1 stop
    $714
    $681
    per traveler
    found 19 hours ago
    Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
  • Dec 15 - Dec 18

    GunRunner Boutique Hotel + Flight

    Florence
    3 nights
    3.5 star property
    9.4/10 - Exceptional (218 reviews)
    Roundtrip • Chicago (CHI) - Muscle Shoals (MSL)
    ORD - MSL • 1 stop MSL - ORD • 1 stop
    $979
    $869
    per traveler
    found 19 hours ago
    GunRunner Boutique Hotel
  • Dec 15 - Dec 18

    The Stricklin Hotel + Flight

    Florence
    3 nights
    3.5 star property
    9.0/10 - Wonderful (949 reviews)
    Roundtrip • Chicago (CHI) - Muscle Shoals (MSL)
    ORD - MSL • 1 stop MSL - ORD • 1 stop
    $884
    $824
    per traveler
    found 19 hours ago
    The Stricklin Hotel
  • Dec 15 - Dec 18

    Budget Inn & Suites + Flight

    East Florence
    3 nights
    2.5 star property
    7.4/10 - Good (194 reviews)
    "Disappointed"
    Reviewed November 3, 2026
    Roundtrip • Chicago (CHI) - Muscle Shoals (MSL)
    ORD - MSL • 1 stop MSL - ORD • 1 stop
    $912
    $857
    per traveler
    found 19 hours ago
    Budget Inn & Suites
  • Dec 15 - Dec 18

    Comfort Suites Florence Shoals Area + Flight

    Florence
    3 nights
    2.5 star property
    8.8/10 - Excellent (886 reviews)
    "Great lodging! We would stay here again!"
    Reviewed November 7, 2026
    Roundtrip • Chicago (CHI) - Muscle Shoals (MSL)
    ORD - MSL • 1 stop MSL - ORD • 1 stop
    $789
    $754
    per traveler
    found 19 hours ago
    Comfort Suites Florence Shoals Area

Discover the most popular places to visit in Wayne County

Wayne County Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.