Wayne Vacations from $644

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Wayne Vacation

Wayne is calling! Whatever type of getaway you're planning, you can see and experience the best of this neighborhood with a Wayne vacation package. Plan enough time to visit well-known nearby attractions such as 8 Seconds Saloon during your trip to Wayne. No matter what your ideal Wayne vacation looks like, you can make it a reality with Expedia.

The Latest Wayne vacation packages

Price found within the past 48 hours. Click for updated prices.
Omni Severin Hotel
Embassy Suites by Hilton Indianapolis North
Two Lakefront Cabins Next Door
Hyatt Place Indianapolis / Fishers
Lakefront Hot tub Amazing Views 35 min to Indy
Don't see what you're looking for?
See all available trips from Columbus to Wayne
View all trips

Stay near popular Wayne attractions

What to do in Wayne

Wayne Hotel Deals

Delta Hotels by Marriott Indianapolis Airport

Delta Hotels by Marriott Indianapolis Airport

3.5 out of 5
5860 Fortune Cir W Indianapolis IN
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $128 total per night from Nov 20 to Nov 21
$128 total
Nov 20 - Nov 21
Total with taxes and fees
8.8/10 Excellent! (900 reviews)
"Processes with a really helpful even called ahead of time and they were able to secure an early check-in for us and our stay super helpful"

Reviewed on Nov 6, 2026

Delta Hotels by Marriott Indianapolis Airport
Baymont by Wyndham Indianapolis Airport Lynhurst

Baymont by Wyndham Indianapolis Airport Lynhurst

3 out of 5
5316 West Southern Ave Indianapolis IN
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $67 total per night from Nov 8 to Nov 9
$67 total
Nov 8 - Nov 9
Total with taxes and fees
5.2/10 (1,004 reviews)
"clean room, micro in the room a plus"

Reviewed on Nov 5, 2026

Baymont by Wyndham Indianapolis Airport Lynhurst
Red Roof Inn & Suites Indianapolis Airport

Red Roof Inn & Suites Indianapolis Airport

2 out of 5
2631 S Lynhurst Dr Indianapolis IN
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $75 total per night from Nov 8 to Nov 9
$75 total
Nov 8 - Nov 9
Total with taxes and fees
Red Roof Inn & Suites Indianapolis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Wayne Vacation Packages

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.