Wilkes Vacations from $621

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Your Wilkes Vacation

Say farewell to the worries of planning and hello to a Wilkes vacation package. With your travel details organized before you go, you can focus on discovering this city, starting with Mississippi District, which is good for shopping, nightlife and bars and pubs. Cascade Station, The Grotto and Edgefield Winery are just a few of the attractions you'll want to see during your trip to Wilkes. Stop daydreaming and start traveling. Explore the broad range of options on Expedia today and put your Wilkes vacation plans in motion!

The Latest Wilkes Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Nines, a Luxury Collection Hotel, Portland

The Nines, a Luxury Collection Hotel, Portland

5 out of 5
Downtown Portland
Price was $872, price is now $621 per person
$621
per person
May 21 - May 26
found 23 hours ago
Roundtrip flight included
Mesa (AZA) to Portland (PDX)
9.2/10 Wonderful! (1,001 reviews)
Loved this hotel. It was one of my favorite hotels that I have stayed in. The staff was amazing and so knowledgeable about the hotel and the area.

Reviewed on Apr 7, 2026

The Independence

The Independence

3 out of 5
Save 100% on your flight
Price was $968, price is now $648 per person
$648
per person
Jun 3 - Jun 9
found 21 hours ago
Roundtrip non-stop flight included
Long Beach (LGB) to Portland (PDX)
9.6/10 Exceptional! (1,012 reviews)
Absolutely beautiful hotel with all the amenities! The room was spacious, bed was extremely comfortable and it even had a balcony with a view of the cute town! Would definitely stay again!

Reviewed on Apr 5, 2026

Sanctuary by the Sea by Avantstay Waterfront + Views

Sanctuary by the Sea by Avantstay Waterfront + Views

3 out of 5
Save 100% on your flight
Price was $4,032, price is now $2,747 per person
$2,747
per person
May 16 - May 23
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Portland (PDX)
No reviews
Sunset Cove by Avantstay Beachfront w/ Balcony!

Sunset Cove by Avantstay Beachfront w/ Balcony!

3.5 out of 5
Save 100% on your flight
Price was $3,788, price is now $2,621 per person
$2,621
per person
May 16 - May 23
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Portland (PDX)
No reviews
The Castle Rock Estate by Avantstay Steps From Arch Cape Beach w/ Hot Tub & Sauna

The Castle Rock Estate by Avantstay Steps From Arch Cape Beach w/ Hot Tub & Sauna

3 out of 5
Save 100% on your flight
Price was $5,913, price is now $4,130 per person
$4,130
per person
Jun 1 - Jun 6
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to Portland (PDX)
No reviews

Where to stay in Wilkes

Find the best Wilkes areas and neighborhoods for the activities you enjoy most. Learn more about Wilkes
Downtown Portland

Downtown Portland

1 out of top 10 points of interest in this area
4.5/5(4,548 area reviews)

Explore the Portland Art Museum, Oregon Historical Society, and Tom McCall Waterfront Park in this central business district with high-rise buildings. Enjoy walkable streets, and easily access public transportation like MAX light rail and Portland Streetcar.

Find hotels in Downtown Portland

Wilkes Hotel Deals

The Paramount Hotel

The Paramount Hotel

3.5 out of 5
808 SW Taylor St Portland OR
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $121 total per night from Apr 22 to Apr 23
$121 total
Apr 22 - Apr 23
Total with taxes and fees
9.2/10 Wonderful! (3,287 reviews)
V nice stay

Reviewed on Apr 7, 2026

The Paramount Hotel
Park Lane Suites and Inn

Park Lane Suites and Inn

2.5 out of 5
809 SW King Avenue Portland OR
Fully refundable
$100 nightly
The price is $116 total per night from Apr 15 to Apr 16
$116 total
Apr 15 - Apr 16
Total with taxes and fees
8.8/10 Excellent! (1,709 reviews)
I stayed in a suite and it was excellent as usual. Clean, quiet and a kitchen with an actual full size fridge along with kitchenware and utensils.

Reviewed on Apr 6, 2026

Park Lane Suites and Inn
The Duniway Portland A Hilton Hotel

The Duniway Portland A Hilton Hotel

4.5 out of 5
545 SW Taylor St Portland OR
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $164 total per night from Apr 19 to Apr 20
$164 total
Apr 19 - Apr 20
Total with taxes and fees
8.6/10 Excellent! (1,002 reviews)
Beautiful hotel! We will definitely be back to stay again

Reviewed on Apr 8, 2026

The Duniway Portland A Hilton Hotel
See all 2,737 properties in Wilkes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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All Inclusive Vacations
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Discover the most popular places to visit in Wilkes

Aerial View of Portland Cityscape with Solar Panels and Highway

Oregon Convention Center

4.5/5(575 reviews)

Learn about the events happening at Oregon Convention Center during your trip to Portland. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Oregon Convention Center
Moda Center

Moda Center

4.5/5(1,189 reviews)

See sporting teams do battle and rock out to musical legends at one of Portland’s major venues for sports and big-ticket entertainment events.

Moda Center
Oregon Zoo

Oregon Zoo

4.5/5(621 reviews)

Awesome beasts native to America have a home alongside exotic and endangered species from around the world at this picturesque Portland attraction.

Oregon Zoo

Things to do

Portland: 2-hour Lunch Cruise on the Willamette River

Portland: 2-Hour Lunch Cruise Through Downtown

$88
per adult
98% of travellers recommend
Portland: 2-Hour Lunch Cruise Through Downtown
Portland: Willamette River 2.5-hour Dinner Cruise

Portland: Dinner Cruise on the Willamette River

$129
per adult
96% of travellers recommend
Portland: Dinner Cruise on the Willamette River
Picture 11 for Activity Portland: Champagne Brunch Cruise on Willamette River

Portland: Brunch Cruise on Willamette River

$105
per adult
92% of travellers recommend
Portland: Brunch Cruise on Willamette River
See all activities in Portland
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.