Zacatecas Centro Vacations from $718

Book a Hotel + Flight or Car together to unlock savings

Photo by Gabriela Butchart
  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Zacatecas Centro Vacation

Immerse yourself in all this neighborhood has to offer with a tailor-made Zacatecas Centro vacation package. However you picture yourself spending your time here, you'll find countless opportunities for fun, adventure and relaxation. Not sure what to do during your trip to Zacatecas Centro? Nearby attractions like Zacatecas Cathedral, El Eden Mine and Bicentennial Plaza are great places to start. Don't just imagine it — make it a reality! Reserve your ideal Zacatecas Centro vacation with Expedia and travel your way.

The Latest Zacatecas Centro Vacation Packages

Price found within the past 48 hours. Click for updated prices.
OYO Hotel Colon, Plaza Bicentenario, Zacatecas Centro
Quinta Real Zacatecas
Fiesta Inn Zacatecas
Hotel Emporio Zacatecas
Casa Cuarzo Hotel Boutique

Zacatecas Centro Hotel Deals

Hotel Emporio Zacatecas

Hotel Emporio Zacatecas

3.5 out of 5
Av. Hidalgo, 703, Centro Historico Zacatecas ZAC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $80 total per night from Nov 9 to Nov 10
$80 total
Nov 9 - Nov 10
Total with taxes and fees
9.4/10 Exceptional! (1,005 reviews)
"Was a great experience. Marcos and Jesus were amazing people not only them there whole team. Thank you for the great experience"

Reviewed on Nov 4, 2026

Hotel Emporio Zacatecas
Hotel Mesón de la Merced

Hotel Mesón de la Merced

3 out of 5
Av Juarez # 114, Centro Historico Zacatecas ZAC
Fully refundableReserve now, pay when you stay
$45 nightly
The price is $54 total per night from Nov 8 to Nov 9
$54 total
Nov 8 - Nov 9
Total with taxes and fees
8.6/10 Excellent! (1,007 reviews)
"The room smelled a drainage leak smell. The heat didn’t work properly. Poor breakfast"

Reviewed on Nov 1, 2026

Hotel Mesón de la Merced
Hotel Argento Zacatecas

Hotel Argento Zacatecas

3.5 out of 5
Avenida Hidalgo No 407 Centro Zacatecas ZAC
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $68 total per night from Nov 18 to Nov 19
$68 total
Nov 18 - Nov 19
Total with taxes and fees
Hotel Argento Zacatecas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Zacatecas Centro attractions

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.